Itgb8 (integrin subunit beta 8) - Rat Genome Database

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Gene: Itgb8 (integrin subunit beta 8) Rattus norvegicus
Analyze
Symbol: Itgb8
Name: integrin subunit beta 8
RGD ID: 1311374
Description: Enables signaling receptor binding activity. Predicted to be involved in several processes, including integrin-mediated signaling pathway; regulation of gene expression; and vasculogenesis. Predicted to act upstream of or within several processes, including hard palate development; mononuclear cell differentiation; and transforming growth factor beta receptor signaling pathway. Predicted to be located in plasma membrane. Predicted to be part of integrin alphav-beta8 complex. Predicted to be active in cell surface and focal adhesion. Orthologous to human ITGB8 (integrin subunit beta 8); PARTICIPATES IN integrin mediated signaling pathway; arrhythmogenic right ventricular cardiomyopathy pathway; cell-extracellular matrix signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: integrin beta 8; integrin beta-8; integrin, beta 8; LOC362800
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86146,267,982 - 146,351,245 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl6146,165,484 - 146,351,245 (-)EnsemblGRCr8
mRatBN7.26140,125,002 - 140,208,261 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6140,127,203 - 140,208,476 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx6143,573,946 - 143,657,246 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06140,191,426 - 140,274,719 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06140,739,279 - 140,829,172 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.06147,089,280 - 147,172,846 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6147,094,097 - 147,172,813 (-)Ensemblrn6Rnor6.0
Rnor_5.06156,002,320 - 156,082,312 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.46146,494,978 - 146,573,064 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera6137,774,003 - 137,851,814 (-)NCBICelera
RGSC_v3.16146,501,164 - 146,578,733 (-)NCBI
Cytogenetic Map6q33NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-hydroxypropanoic acid  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
3-methylcholanthrene  (EXP)
6-propyl-2-thiouracil  (EXP)
acrolein  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
alpha-naphthoflavone  (EXP)
alpha-pinene  (ISO)
alpha-Zearalanol  (EXP)
amitrole  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
Azoxymethane  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
choline  (ISO)
cobalt atom  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
crotonaldehyde  (ISO)
Cuprizon  (EXP)
DDE  (ISO)
dextran sulfate  (ISO)
dibutyl phthalate  (ISO)
dimethylarsinic acid  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
fluoranthene  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
gentamycin  (EXP)
L-methionine  (ISO)
lipopolysaccharide  (ISO)
lithium chloride  (ISO)
malathion  (ISO)
maneb  (ISO)
metformin  (EXP)
methimazole  (EXP)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
methylarsonic acid  (ISO)
methylmercury chloride  (ISO)
nickel dichloride  (ISO)
Nutlin-3  (ISO)
oxaliplatin  (ISO)
ozone  (ISO)
paracetamol  (EXP)
paraquat  (EXP,ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP,ISO)
phenylephrine  (EXP)
phenylmercury acetate  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
poly(I:C)  (ISO)
potassium dichromate  (ISO)
progesterone  (ISO)
pterostilbene  (ISO)
pyridaben  (ISO)
rac-lactic acid  (ISO)
Rutecarpine  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
S-nitrosoglutathione  (ISO)
SB 431542  (ISO)
serpentine asbestos  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
temozolomide  (ISO)
tetrachloromethane  (ISO)
thiram  (ISO)
titanium dioxide  (EXP,ISO)
trichostatin A  (ISO)
triclosan  (ISO)
trimellitic anhydride  (ISO)
Tungsten carbide  (ISO)
valproic acid  (EXP,ISO)
vincristine  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Integrins: bidirectional, allosteric signaling machines. Hynes RO Cell 2002 Sep 20;110(6):673-87.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. The integrins. Takada Y, etal., Genome Biol. 2007;8(5):215.
10. Calcium-sensing receptor modulates cell adhesion and migration via integrins. Tharmalingam S, etal., J Biol Chem. 2011 Nov 25;286(47):40922-33. doi: 10.1074/jbc.M111.265454. Epub 2011 Oct 3.
Additional References at PubMed
PMID:1918072   PMID:7525578   PMID:12050137   PMID:16251442   PMID:19056867   PMID:22278742   PMID:23376485   PMID:24312400   PMID:24461183   PMID:25801897   PMID:31894320   PMID:37931653  


Genomics

Comparative Map Data
Itgb8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86146,267,982 - 146,351,245 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl6146,165,484 - 146,351,245 (-)EnsemblGRCr8
mRatBN7.26140,125,002 - 140,208,261 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6140,127,203 - 140,208,476 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx6143,573,946 - 143,657,246 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06140,191,426 - 140,274,719 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06140,739,279 - 140,829,172 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.06147,089,280 - 147,172,846 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6147,094,097 - 147,172,813 (-)Ensemblrn6Rnor6.0
Rnor_5.06156,002,320 - 156,082,312 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.46146,494,978 - 146,573,064 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera6137,774,003 - 137,851,814 (-)NCBICelera
RGSC_v3.16146,501,164 - 146,578,733 (-)NCBI
Cytogenetic Map6q33NCBI
ITGB8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38720,329,766 - 20,415,754 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl720,330,609 - 20,415,754 (+)Ensemblhg38GRCh38
GRCh37720,370,523 - 20,455,377 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36720,337,250 - 20,421,907 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34720,143,985 - 20,223,659NCBI
Celera720,354,962 - 20,439,624 (+)NCBICelera
Cytogenetic Map7p21.1NCBI
HuRef720,258,397 - 20,343,469 (+)NCBIHuRef
CHM1_1720,370,975 - 20,455,655 (+)NCBICHM1_1
T2T-CHM13v2.0720,464,766 - 20,550,710 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2720,422,044 - 20,506,723 (+)NCBI
Itgb8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912119,121,757 - 119,202,891 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12119,121,757 - 119,202,537 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm3812119,162,803 - 119,238,276 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12119,158,022 - 119,238,802 (-)Ensemblmm10GRCm38
MGSCv3712120,401,276 - 120,476,749 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3612119,602,124 - 119,682,903 (-)NCBIMGSCv36mm8
MGSCv3612113,383,602 - 113,464,521 (-)NCBIMGSCv36mm8
Cytogenetic Map12F2NCBI
cM Map1263.48NCBI
Itgb8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541023,011,973 - 23,097,021 (+)Ensembl
ChiLan1.0NW_00495541023,011,874 - 23,099,191 (+)NCBIChiLan1.0ChiLan1.0
ITGB8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2625,198,693 - 25,283,917 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1773,523,421 - 73,608,644 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0721,019,917 - 21,105,143 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1720,336,031 - 20,415,666 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl720,336,031 - 20,415,666 (+)EnsemblpanPan2panpan1.1
ITGB8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11434,370,957 - 34,449,091 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1434,349,232 - 34,444,235 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1433,907,455 - 33,985,373 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01434,291,410 - 34,369,408 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1434,292,368 - 34,369,397 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11434,409,582 - 34,487,497 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01434,110,235 - 34,188,365 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01434,421,084 - 34,499,007 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Itgb8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511878,677,498 - 78,772,514 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365466,353,986 - 6,442,756 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365466,352,186 - 6,447,458 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ITGB8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl989,341,162 - 89,448,665 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1989,342,245 - 89,450,701 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2998,589,298 - 98,771,852 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ITGB8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12137,811,811 - 37,896,539 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2137,817,572 - 37,895,560 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604266,676,831 - 66,761,359 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Itgb8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473910,168,495 - 10,259,804 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473910,164,645 - 10,261,732 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Itgb8
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v17116,906,842 - 116,986,340 (+)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:21
Count of miRNA genes:19
Interacting mature miRNAs:21
Transcripts:ENSRNOT00000066545
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331797Bp213Blood pressure QTL 2133.291arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)6114241077147156653Rat
4145118Mcs26Mammary carcinoma susceptibility QTL 260.0001mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)6112483610147156653Rat
737976Pia24Pristane induced arthritis QTL 24joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)6118366855147156653Rat
1298087Iddm18Insulin dependent diabetes mellitus QTL 180.0001urine glucose amount (VT:0001758)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)6122236101147156653Rat
71111Iddm8Insulin dependent diabetes mellitus QTL 81.90.002blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)6110921244147156653Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6106095977147156653Rat
12801471Schws9Schwannoma susceptibility QTL 9nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)6101593607146593607Rat
2293085Iddm29Insulin dependent diabetes mellitus QTL 297.66blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)6121444670147156653Rat

Markers in Region
BF386390  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26140,196,093 - 140,196,278 (+)MAPPERmRatBN7.2
Rnor_6.06147,160,680 - 147,160,864NCBIRnor6.0
Rnor_5.06156,070,141 - 156,070,325UniSTSRnor5.0
RGSC_v3.46146,561,055 - 146,561,239UniSTSRGSC3.4
Celera6137,840,077 - 137,840,261UniSTS
RH 3.4 Map6899.1UniSTS
Cytogenetic Map6q33UniSTS
ITGB8  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26140,129,915 - 140,130,331 (+)MAPPERmRatBN7.2
Rnor_6.06147,094,194 - 147,094,609NCBIRnor6.0
Rnor_5.06156,003,655 - 156,004,070UniSTSRnor5.0
RGSC_v3.46146,494,877 - 146,495,292UniSTSRGSC3.4
Celera6137,773,902 - 137,774,317UniSTS
Cytogenetic Map6q33UniSTS
MARC_23311-23312:1024579300:3  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26140,156,685 - 140,157,351 (+)MAPPERmRatBN7.2
Rnor_6.06147,120,964 - 147,121,629NCBIRnor6.0
Rnor_5.06156,030,425 - 156,031,090UniSTSRnor5.0
RGSC_v3.46146,521,647 - 146,522,312UniSTSRGSC3.4
Celera6137,800,672 - 137,801,337UniSTS
Cytogenetic Map6q33UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
21 10 78 180 80 79 48 81 48 6 381 191 13 165 113 114 31 27 27

Sequence


Ensembl Acc Id: ENSRNOT00000066545   ⟹   ENSRNOP00000060968
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl6146,267,989 - 146,351,245 (-)Ensembl
mRatBN7.2 Ensembl6140,127,203 - 140,208,232 (-)Ensembl
Rnor_6.0 Ensembl6147,094,295 - 147,172,813 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000080675   ⟹   ENSRNOP00000069619
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl6146,267,989 - 146,351,245 (-)Ensembl
mRatBN7.2 Ensembl6140,127,203 - 140,208,476 (-)Ensembl
Rnor_6.0 Ensembl6147,094,097 - 147,172,022 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000137663   ⟹   ENSRNOP00000105872
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl6146,165,484 - 146,351,245 (-)Ensembl
RefSeq Acc Id: NM_001401817   ⟹   NP_001388746
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86146,267,989 - 146,351,245 (-)NCBI
mRatBN7.26140,125,002 - 140,208,261 (-)NCBI
RefSeq Acc Id: XM_063262164   ⟹   XP_063118234
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86146,267,982 - 146,311,526 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001388746 (Get FASTA)   NCBI Sequence Viewer  
  XP_063118234 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL89094 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000060968.2
  ENSRNOP00000069619
  ENSRNOP00000069619.1
  ENSRNOP00000105872.1
Ensembl Acc Id: ENSRNOP00000069619   ⟸   ENSRNOT00000080675
Ensembl Acc Id: ENSRNOP00000060968   ⟸   ENSRNOT00000066545
RefSeq Acc Id: NP_001388746   ⟸   NM_001401817
- UniProtKB: A0A0G2JVU1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063118234   ⟸   XM_063262164
- Peptide Label: isoform X1
- UniProtKB: A6KDM9 (UniProtKB/TrEMBL),   D3ZP06 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000105872   ⟸   ENSRNOT00000137663
Protein Domains
EGF-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JVU1-F1-model_v2 AlphaFold A0A0G2JVU1 1-767 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694912
Promoter ID:EPDNEW_R5437
Type:initiation region
Name:Itgb8_1
Description:integrin subunit beta 8
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.06147,172,876 - 147,172,936EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311374 AgrOrtholog
BioCyc Gene G2FUF-35454 BioCyc
Ensembl Genes ENSRNOG00000006569 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000066545.3 UniProtKB/TrEMBL
  ENSRNOT00000080675 ENTREZGENE
  ENSRNOT00000080675.3 UniProtKB/TrEMBL
  ENSRNOT00000137663.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.410 UniProtKB/TrEMBL
  Laminin UniProtKB/TrEMBL
  ligand-binding face of the semaphorins, domain 2 UniProtKB/TrEMBL
  ntegrin, alpha v. Chain A, domain 3 UniProtKB/TrEMBL
InterPro EGF-like_dom UniProtKB/TrEMBL
  EGF_extracell UniProtKB/TrEMBL
  EGF_integrin_2 UniProtKB/TrEMBL
  Integin_beta_N UniProtKB/TrEMBL
  Integrin_bsu UniProtKB/TrEMBL
  Integrin_bsu_N UniProtKB/TrEMBL
  Integrin_dom UniProtKB/TrEMBL
  Integrin_I-EGF_CS UniProtKB/TrEMBL
  Plexin-like_fold UniProtKB/TrEMBL
  vWFA_dom_sf UniProtKB/TrEMBL
NCBI Gene 362800 ENTREZGENE
PANTHER Integrin_beta_C UniProtKB/TrEMBL
  PTHR10082:SF9 UniProtKB/TrEMBL
Pfam EGF_2 UniProtKB/TrEMBL
  EGF_integrin UniProtKB/TrEMBL
  Integrin_beta UniProtKB/TrEMBL
  PSI_integrin UniProtKB/TrEMBL
PhenoGen Itgb8 PhenoGen
PIRSF Integrin_B UniProtKB/TrEMBL
PRINTS INTEGRINB UniProtKB/TrEMBL
PROSITE EGF_1 UniProtKB/TrEMBL
  I_EGF_2 UniProtKB/TrEMBL
  INTEGRIN_BETA UniProtKB/TrEMBL
RatGTEx ENSRNOG00000006569 RatGTEx
SMART INB UniProtKB/TrEMBL
  PSI UniProtKB/TrEMBL
Superfamily-SCOP EGF/Laminin UniProtKB/TrEMBL
  Plexin repeat UniProtKB/TrEMBL
  SSF53300 UniProtKB/TrEMBL
  SSF69179 UniProtKB/TrEMBL
UniProt A0A0G2JVU1 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0L719_RAT UniProtKB/TrEMBL
  A6KDM9 ENTREZGENE, UniProtKB/TrEMBL
  D3ZP06 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-23 Itgb8  integrin subunit beta 8  Itgb8  integrin, beta 8  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-02-09 Itgb8  integrin, beta 8  Itgb8  integrin beta 8   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Itgb8  integrin beta 8   Itgb8_predicted  integrin beta 8 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Itgb8_predicted  integrin beta 8 (predicted)      Symbol and Name status set to approved 70820 APPROVED