Qng1 (Q-nucleotide N-glycosylase 1) - Rat Genome Database

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Gene: Qng1 (Q-nucleotide N-glycosylase 1) Rattus norvegicus
Analyze
Symbol: Qng1
Name: Q-nucleotide N-glycosylase 1
RGD ID: 1311345
Description: Predicted to enable queuosine nucleosidase activity. Predicted to be involved in nucleoside salvage and tRNA modification. Predicted to be active in cytosol. Orthologous to human QNG1 (Q-nucleotide N-glycosylase 1); INTERACTS WITH 4,4'-sulfonyldiphenol; amitrole; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: hypothetical protein LOC361201; LOC361201; MGC112925; queuosine 5'-phosphate N-glycosylase/hydrolase; RGD1311345; similar to CG9752-PA; uncharacterized protein LOC361201; UPF0553 protein C9orf64 homolog
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8176,286,801 - 6,294,400 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl176,286,827 - 6,294,399 (+)EnsemblGRCr8
mRatBN7.2176,281,377 - 6,288,976 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl176,281,400 - 6,288,975 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx176,304,129 - 6,311,726 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0177,837,472 - 7,844,364 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0176,300,502 - 6,308,103 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0176,683,152 - 6,690,724 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl176,683,152 - 6,690,723 (+)Ensemblrn6Rnor6.0
Rnor_5.0178,887,525 - 8,895,097 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41712,212,222 - 12,219,878 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera176,391,119 - 6,398,686 (+)NCBICelera
RGSC_v3.11712,212,215 - 12,218,802 (+)NCBI
Cytogenetic Map17p14NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932  


Genomics

Comparative Map Data
Qng1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8176,286,801 - 6,294,400 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl176,286,827 - 6,294,399 (+)EnsemblGRCr8
mRatBN7.2176,281,377 - 6,288,976 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl176,281,400 - 6,288,975 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx176,304,129 - 6,311,726 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0177,837,472 - 7,844,364 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0176,300,502 - 6,308,103 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0176,683,152 - 6,690,724 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl176,683,152 - 6,690,723 (+)Ensemblrn6Rnor6.0
Rnor_5.0178,887,525 - 8,895,097 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41712,212,222 - 12,219,878 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera176,391,119 - 6,398,686 (+)NCBICelera
RGSC_v3.11712,212,215 - 12,218,802 (+)NCBI
Cytogenetic Map17p14NCBI
QNG1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38983,938,311 - 83,956,986 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl983,938,311 - 83,956,986 (-)Ensemblhg38GRCh38
GRCh37986,553,226 - 86,571,901 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36985,743,046 - 85,761,483 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34983,782,782 - 83,801,455NCBI
Celera957,124,248 - 57,142,674 (-)NCBICelera
Cytogenetic Map9q21.32NCBI
HuRef956,378,909 - 56,397,294 (-)NCBIHuRef
CHM1_1986,699,916 - 86,718,354 (-)NCBICHM1_1
T2T-CHM13v2.0996,088,591 - 96,107,266 (-)NCBIT2T-CHM13v2.0
Qng1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391358,527,860 - 58,533,039 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1358,527,631 - 58,533,039 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381358,380,046 - 58,385,225 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1358,379,817 - 58,385,225 (-)Ensemblmm10GRCm38
MGSCv371358,481,407 - 58,486,586 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
Celera1359,442,408 - 59,447,588 (-)NCBICelera
Cytogenetic Map13B1NCBI
cM Map1331.04NCBI
Qng1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554323,273,161 - 3,288,035 (+)Ensembl
ChiLan1.0NW_0049554323,273,161 - 3,284,261 (+)NCBIChiLan1.0ChiLan1.0
QNG1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21183,097,251 - 83,115,894 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1983,103,194 - 83,121,833 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0940,921,349 - 40,940,380 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1983,294,908 - 83,313,024 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl983,294,908 - 83,312,792 (-)EnsemblpanPan2panpan1.1
QNG1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1175,526,468 - 75,538,740 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl175,526,674 - 75,538,381 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha176,176,386 - 76,188,637 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0175,827,816 - 75,840,080 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl175,827,783 - 75,840,073 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1175,641,751 - 75,654,004 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0175,404,593 - 75,416,857 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0176,107,462 - 76,119,721 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Qng1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947122,205,562 - 122,213,890 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936828810,088 - 819,675 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936828810,332 - 820,018 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
QNG1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1031,001,005 - 31,016,753 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11031,000,959 - 31,011,431 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21035,066,634 - 35,077,300 (-)NCBISscrofa10.2Sscrofa10.2susScr3
QNG1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11294,750,924 - 94,767,092 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1294,749,789 - 94,766,914 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603883,168,788 - 83,185,597 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Qng1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248097,506,605 - 7,525,788 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248097,508,683 - 7,525,983 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Qng1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11479,750,496 - 79,758,101 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Qng1
37 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:180
Count of miRNA genes:139
Interacting mature miRNAs:154
Transcripts:ENSRNOT00000061249
Prediction methods:Miranda, Pita, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354613Kidm14Kidney mass QTL 146.2kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)17136045694Rat
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17143999106Rat
2293664Bmd28Bone mineral density QTL 285.10.0001femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)17436005727233623Rat
2324619Coatc4Coat color QTL 40.001coat/hair pigmentation trait (VT:0010463)pigmented dorsal coat/hair area to total dorsal coat/hair area ratio (CMO:0001811)17121499218Rat
1300123Bp194Blood pressure QTL 1942.82arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)17212084342054133Rat
2303627Vencon8Ventilatory control QTL 80.001respiration trait (VT:0001943)tidal volume (CMO:0000222)17473353449733534Rat
2302377Scl61Serum cholesterol level QTL 614.36blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)17622199858177198Rat
631207Niddm41Non-insulin dependent diabetes mellitus QTL 41blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)17138037084Rat
10401807Kidm52Kidney mass QTL 52kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)17131706603Rat
10054088Scort28Serum corticosterone level QTL 282.040.0102blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17473353449733534Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17143999106Rat
2293648Bmd31Bone mineral density QTL 314.50.0001femur size trait (VT:1000369)femoral neck cortical cross-sectional area (CMO:0001702)17436005727233623Rat
1354658Spl8Serum phospholipid level QTL 83.8blood VLDL phospholipid amount (VT:0010507)blood very low density lipoprotein phospholipid level (CMO:0001571)17143999106Rat
1641902Colcr7Colorectal carcinoma resistance QTL 73.350.0044intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)17212084322087569Rat
1549900Iddm20Insulin dependent diabetes mellitus QTL 203.7pancreas integrity trait (VT:0010560)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)17122181410Rat
9590316Scort21Serum corticosterone level QTL 214.750.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17122877318Rat

Markers in Region
RH131493  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21343,346,742 - 43,346,926 (+)MAPPERmRatBN7.2
mRatBN7.2176,288,728 - 6,288,911 (+)MAPPERmRatBN7.2
Rnor_6.0176,690,477 - 6,690,659NCBIRnor6.0
Rnor_6.01348,681,415 - 48,681,598NCBIRnor6.0
Rnor_5.01353,754,936 - 53,755,119UniSTSRnor5.0
Rnor_5.0178,894,850 - 8,895,032UniSTSRnor5.0
RGSC_v3.41712,219,543 - 12,219,725UniSTSRGSC3.4
Celera176,398,439 - 6,398,621UniSTS
Celera1343,683,783 - 43,683,966UniSTS
Cytogenetic Map6q33UniSTS
Cytogenetic Map17p14UniSTS
RH140116  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2176,287,809 - 6,288,019 (+)MAPPERmRatBN7.2
Rnor_6.0176,689,558 - 6,689,767NCBIRnor6.0
Rnor_5.0178,893,931 - 8,894,140UniSTSRnor5.0
RGSC_v3.41712,218,624 - 12,218,833UniSTSRGSC3.4
Celera176,397,520 - 6,397,729UniSTS
RH 3.4 Map1769.8UniSTS
Cytogenetic Map17p14UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 92 59 6 356 192 11 143 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000061249   ⟹   ENSRNOP00000057961
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl176,286,827 - 6,294,399 (+)Ensembl
mRatBN7.2 Ensembl176,281,400 - 6,288,975 (+)Ensembl
Rnor_6.0 Ensembl176,683,152 - 6,690,723 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000089138   ⟹   ENSRNOP00000073107
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl176,288,297 - 6,294,399 (+)Ensembl
mRatBN7.2 Ensembl176,282,869 - 6,288,975 (+)Ensembl
Rnor_6.0 Ensembl176,684,621 - 6,690,723 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000104923   ⟹   ENSRNOP00000091026
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl176,281,775 - 6,288,144 (+)Ensembl
RefSeq Acc Id: NM_001173436   ⟹   NP_001166907
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8176,286,828 - 6,294,400 (+)NCBI
mRatBN7.2176,281,400 - 6,288,976 (+)NCBI
Rnor_6.0176,683,152 - 6,690,724 (+)NCBI
Rnor_5.0178,887,525 - 8,895,097 (+)NCBI
Celera176,391,119 - 6,398,686 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039095848   ⟹   XP_038951776
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8176,286,801 - 6,294,400 (+)NCBI
mRatBN7.2176,281,377 - 6,288,976 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001166907 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951776 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH98862 (Get FASTA)   NCBI Sequence Viewer  
  AAI68185 (Get FASTA)   NCBI Sequence Viewer  
  EDL93911 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000057961
  ENSRNOP00000057961.3
  ENSRNOP00000073107.1
RefSeq Acc Id: NP_001166907   ⟸   NM_001173436
- UniProtKB: F7FM32 (UniProtKB/TrEMBL),   A6KAK3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000073107   ⟸   ENSRNOT00000089138
Ensembl Acc Id: ENSRNOP00000057961   ⟸   ENSRNOT00000061249
RefSeq Acc Id: XP_038951776   ⟸   XM_039095848
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000091026   ⟸   ENSRNOT00000104923

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F7FM32-F1-model_v2 AlphaFold F7FM32 1-341 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700280
Promoter ID:EPDNEW_R10803
Type:multiple initiation site
Name:RGD1311345_1
Description:similar to CG9752-PA
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0176,683,172 - 6,683,232EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311345 AgrOrtholog
BioCyc Gene G2FUF-10354 BioCyc
Ensembl Genes ENSRNOG00000019232 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000061249 ENTREZGENE
  ENSRNOT00000061249.5 UniProtKB/TrEMBL
  ENSRNOT00000089138.3 UniProtKB/TrEMBL
InterPro DUF2419 UniProtKB/TrEMBL
KEGG Report rno:361201 UniProtKB/TrEMBL
NCBI Gene 361201 ENTREZGENE
PANTHER PTHR21314 UniProtKB/TrEMBL
  QUEUOSINE SALVAGE PROTEIN UniProtKB/TrEMBL
Pfam DUF2419 UniProtKB/TrEMBL
PhenoGen Qng1 PhenoGen
RatGTEx ENSRNOG00000019232 RatGTEx
UniProt A6KAK3 ENTREZGENE, UniProtKB/TrEMBL
  B4F797_RAT UniProtKB/TrEMBL
  F7FM32 ENTREZGENE, UniProtKB/TrEMBL
  Q4KM26_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-03-09 Qng1  Q-nucleotide N-glycosylase 1  RGD1311345  similar to CG9752-PA  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 RGD1311345  similar to CG9752-PA  RGD1311345_predicted  similar to CG9752-PA (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1311345_predicted  similar to CG9752-PA (predicted)  LOC361201_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC361201_predicted  similar to CG9752-PA (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL