Advanced Search (OLGA)

Gene: Abcb10 (ATP binding cassette subfamily B member 10) Rattus norvegicus

Analyze

Symbol:

Abcb10

Name:

ATP binding cassette subfamily B member 10

RGD ID:

1311222

Description:

Predicted to enable several functions, including ABC-type oligopeptide transporter activity; ATP binding activity; and ATP hydrolysis activity. Predicted to be involved in several processes, including mitochondrial unfolded protein response; oligopeptide export from mitochondrion; and positive regulation of erythrocyte differentiation. Predicted to be located in mitochondrial membrane. Predicted to be active in mitochondrial inner membrane. Orthologous to human ABCB10 (ATP binding cassette subfamily B member 10); INTERACTS WITH acetamide; aflatoxin B1; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

ATP-binding cassette sub-family B member 10, mitochondrial; ATP-binding cassette, sub-family B (MDR/TAP), member 10; ATP-binding cassette, subfamily B (MDR/TAP), member 10; LOC361439; MGC109142

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ABCB10 (ATP binding cassette subfamily B member 10)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Abcb10 (ATP-binding cassette, sub-family B member 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Abcb10 (ATP binding cassette subfamily B member 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ABCB10 (ATP binding cassette subfamily B member 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ABCB10 (ATP binding cassette subfamily B member 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Abcb10 (ATP binding cassette subfamily B member 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ABCB10 (ATP binding cassette subfamily B member 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ABCB10 (ATP binding cassette subfamily B member 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Abcb10 (ATP binding cassette subfamily B member 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Abcb10 (ATP binding cassette subfamily B member 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	CLYBL (citramalyl-CoA lyase)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	ABCB10 (ATP binding cassette subfamily B member 10)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	ABCB10 (ATP binding cassette subfamily B member 10)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Abcb10 (ATP-binding cassette, sub-family B member 10)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	abcb10 (ATP-binding cassette, sub-family B (MDR/TAP), member 10)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG3156	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG3156	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	MDL1	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	MDL1	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	MDL2	Alliance	DIOPT (InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	MDL2	Alliance	DIOPT (InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	haf-1	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	haf-1	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	haf-3	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	haf-3	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	abcb10	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	19	68,850,108 - 68,881,689 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	19	68,850,134 - 68,880,203 (-)	Ensembl				GRCr8
mRatBN7.2	19	51,952,655 - 51,982,910 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	19	51,952,681 - 51,982,753 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	19	58,736,070 - 58,766,133 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	19	59,588,145 - 59,618,408 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	19	61,662,495 - 61,692,560 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	19	56,742,809 - 56,772,904 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	19	56,742,835 - 56,772,904 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	19	67,458,422 - 67,488,456 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	19	54,151,400 - 54,181,495 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	19	51,327,207 - 51,357,149 (-)	NCBI		Celera
RGSC_v3.1	19	54,156,300 - 54,186,376 (-)	NCBI
Cytogenetic Map	19	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Colorectal Neoplasms (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

(1->4)-beta-D-glucan (ISO)

1,2-dichloroethane (ISO)

17alpha-ethynylestradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2-butoxyethanol (ISO)

4,4'-sulfonyldiphenol (ISO)

acetamide (EXP)

aflatoxin B1 (EXP,ISO)

Aflatoxin B2 alpha (ISO)

all-trans-retinoic acid (ISO)

aristolochic acid A (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP)

butanal (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

calcitriol (ISO)

choline (ISO)

cisplatin (ISO)

cobalt dichloride (ISO)

copper atom (ISO)

copper(0) (ISO)

copper(II) sulfate (ISO)

CU-O LINKAGE (ISO)

cyclosporin A (ISO)

Dibutyl phosphate (ISO)

dibutyl phthalate (ISO)

doxorubicin (ISO)

epoxiconazole (ISO)

eugenol (EXP)

flutamide (EXP)

folic acid (ISO)

gentamycin (EXP)

L-methionine (ISO)

microcystin-LR (ISO)

N,N-diethyl-m-toluamide (EXP)

N-nitrosomorpholine (EXP)

oxaliplatin (EXP)

paracetamol (EXP,ISO)

perfluorooctane-1-sulfonic acid (ISO)

permethrin (EXP)

phosphane (EXP)

pinosylvin (ISO)

potassium dichromate (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenite (ISO)

Soman (EXP)

sulforaphane (ISO)

thioacetamide (EXP)

topotecan (EXP)

trans-pinosylvin (ISO)

trichloroethene (EXP)

triphenyl phosphate (ISO)

troglitazone (ISO)

urethane (ISO)

valproic acid (EXP,ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

erythrocyte development (IEA,ISO)

export from the mitochondrion (IEA,ISO)

heme biosynthetic process (IEA,ISO)

mitochondrial unfolded protein response (IEA,ISO)

oligopeptide export from mitochondrion (IBA)

positive regulation of erythrocyte differentiation (IEA,ISO)

positive regulation of hemoglobin biosynthetic process (IEA,ISO)

transmembrane transport (IEA)

Cellular Component

ATP-binding cassette (ABC) transporter complex (IEA,ISO)

membrane (IEA)

mitochondrial inner membrane (IBA,IEA,ISO)

mitochondrial membrane (IEA,ISO)

mitochondrion (IEA,ISO)

Molecular Function

ABC-type oligopeptide transporter activity (IBA)

ABC-type transporter activity (IEA,ISO)

ATP binding (IEA,ISO)

ATP hydrolysis activity (IEA,ISO)

identical protein binding (IEA,ISO)

metal ion binding (IEA)

nucleotide binding (IEA)

protein binding (ISO)

protein homodimerization activity (IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	GOA pipeline	RGD automated data pipeline
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
6.	Comprehensive gene review and curation	RGD comprehensive gene curation

Additional References at PubMed

PMID:10835348	PMID:10922475	PMID:12477932	PMID:12865426	PMID:15215243	PMID:18614015

Genomics

Comparative Map Data

Abcb10
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	19	68,850,108 - 68,881,689 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	19	68,850,134 - 68,880,203 (-)	Ensembl				GRCr8
mRatBN7.2	19	51,952,655 - 51,982,910 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	19	51,952,681 - 51,982,753 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	19	58,736,070 - 58,766,133 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	19	59,588,145 - 59,618,408 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	19	61,662,495 - 61,692,560 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	19	56,742,809 - 56,772,904 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	19	56,742,835 - 56,772,904 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	19	67,458,422 - 67,488,456 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	19	54,151,400 - 54,181,495 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	19	51,327,207 - 51,357,149 (-)	NCBI		Celera
RGSC_v3.1	19	54,156,300 - 54,186,376 (-)	NCBI
Cytogenetic Map	19	q12	NCBI

ABCB10
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	229,516,582 - 229,558,707 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	229,516,582 - 229,558,957 (-)	Ensembl			hg38	GRCh38
GRCh37	1	229,652,329 - 229,694,454 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	227,718,953 - 227,761,065 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	1	225,959,064 - 226,001,177	NCBI
Celera	1	202,920,623 - 202,962,354 (-)	NCBI		Celera
Cytogenetic Map	1	q42.13	NCBI
HuRef	1	200,142,671 - 200,175,525 (-)	NCBI		HuRef
CHM1_1	1	230,924,663 - 230,966,754 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	228,895,342 - 228,937,469 (-)	NCBI		T2T-CHM13v2.0

Abcb10
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	124,679,198 - 124,709,877 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	124,679,198 - 124,709,861 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	8	123,952,459 - 123,983,122 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	123,952,459 - 123,983,122 (-)	Ensembl			mm10	GRCm38
MGSCv37	8	126,476,359 - 126,507,022 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	8	126,838,549 - 126,869,212 (-)	NCBI		MGSCv36	mm8
Celera	8	128,227,020 - 128,263,115 (-)	NCBI		Celera
Cytogenetic Map	8	E2	NCBI
cM Map	8	72.31	NCBI

Abcb10
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955492	8,532,240 - 8,577,041 (+)	Ensembl
ChiLan1.0	NW_004955492	8,532,240 - 8,573,211 (+)	NCBI	ChiLan1.0	ChiLan1.0

ABCB10
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	19,653,065 - 19,695,228 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	19,845,357 - 19,887,515 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	205,061,329 - 205,103,568 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	210,092,755 - 210,134,061 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	210,094,355 - 210,134,496 (-)	Ensembl			panPan2	panpan1.1

ABCB10
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	4	9,711,509 - 9,746,785 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	4	9,711,100 - 9,745,106 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	4	9,702,226 - 9,737,954 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	4	9,741,696 - 9,777,427 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	4	9,741,480 - 9,777,422 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	4	9,745,419 - 9,781,139 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	4	9,860,036 - 9,895,735 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	4	10,112,058 - 10,147,786 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Abcb10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	43,989,241 - 44,014,346 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936484	20,155,595 - 20,180,183 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936484	20,154,467 - 20,179,748 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ABCB10
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	60,309,931 - 60,346,280 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	14	60,309,893 - 60,346,283 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	65,142,017 - 65,168,725 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ABCB10
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	25	66,786,618 - 66,829,118 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	25	66,786,484 - 66,828,916 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666055	68,647,514 - 68,689,837 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Abcb10
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624775	19,546,192 - 19,578,728 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624775	19,546,002 - 19,579,767 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Abcb10
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	17	43,505,480 - 43,536,397 (-)	NCBI		Rrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	145
Count of miRNA genes:	113
Interacting mature miRNAs:	127
Transcripts:	ENSRNOT00000024232
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
724546	Kidm3	Kidney mass QTL 3	3.1		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	19	46226778	74246245	Rat
631840	Niddm38	Non-insulin dependent diabetes mellitus QTL 38	3.86		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	19	10329076	74246245	Rat
7411549	Bw130	Body weight QTL 130	5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	19	32365311	74246245	Rat
724518	Uae19	Urinary albumin excretion QTL 19	5.5		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	19	24093973	69093973	Rat
1331737	Uae29	Urinary albumin excretion QTL 29	5.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	19	36289	74246245	Rat
61423	Cia14	Collagen induced arthritis QTL 14	3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	19	10833618	74246245	Rat
2313395	Anxrr26	Anxiety related response QTL 26			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	19	44385134	74246245	Rat
1578764	Stresp19	Stress response QTL 19	3.6	0.001	blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	19	32539615	74246245	Rat
5135224	Leukc1	Leukocyte quantity QTL 1			eosinophil quantity (VT:0002602)	blood eosinophil count (CMO:0000033)	19	61249161	74246245	Rat
1331788	Rf45	Renal function QTL 45	2.818		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	19	31777888	74246245	Rat
1549835	Tcas7	Tongue tumor susceptibility QTL 7		0.001	tongue integrity trait (VT:0010553)	squamous cell carcinoma of the head and neck tumor number (CMO:0001876)	19	41722546	74246245	Rat
7247442	Uae39	Urinary albumin excretion QTL 39			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	19	2194317	74246245	Rat
724566	Uae12	Urinary albumin excretion QTL 12	5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	19	2194317	74246245	Rat

Markers in Region

RH127611

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	19	51,952,371 - 51,952,561 (+)	MAPPER	mRatBN7.2
Rnor_6.0	19	56,742,526 - 56,742,715	NCBI	Rnor6.0
Rnor_5.0	19	67,458,139 - 67,458,328	UniSTS	Rnor5.0
RGSC_v3.4	19	54,151,117 - 54,151,306	UniSTS	RGSC3.4
Celera	19	51,326,924 - 51,327,113	UniSTS
RH 3.4 Map	19	716.6	UniSTS
Cytogenetic Map	19	q12	UniSTS

BI276801

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	19	51,952,843 - 51,953,002 (+)	MAPPER	mRatBN7.2
Rnor_6.0	19	56,742,998 - 56,743,156	NCBI	Rnor6.0
Rnor_5.0	19	67,458,611 - 67,458,769	UniSTS	Rnor5.0
RGSC_v3.4	19	54,151,589 - 54,151,747	UniSTS	RGSC3.4
Celera	19	51,327,396 - 51,327,554	UniSTS
RH 3.4 Map	19	713.01	UniSTS
Cytogenetic Map	19	q12	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	161	91	90	59	92	59	6	356	192	11	140	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001012166	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039097899	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063278167	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063278168	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC133405	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC089900	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000019	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000024232 ⟹ ENSRNOP00000024232

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	19	68,850,134 - 68,880,203 (-)	Ensembl
mRatBN7.2 Ensembl	19	51,952,681 - 51,982,753 (-)	Ensembl
Rnor_6.0 Ensembl	19	56,742,835 - 56,772,904 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000113091 ⟹ ENSRNOP00000096653

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	19	68,851,349 - 68,880,203 (-)	Ensembl
mRatBN7.2 Ensembl	19	51,953,896 - 51,982,744 (-)	Ensembl

RefSeq Acc Id:

NM_001012166 ⟹ NP_001012166

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	19	68,850,108 - 68,880,203 (-)	NCBI
mRatBN7.2	19	51,952,655 - 51,982,753 (-)	NCBI
Rnor_6.0	19	56,742,809 - 56,772,904 (-)	NCBI
Rnor_5.0	19	67,458,422 - 67,488,456 (-)	NCBI
RGSC_v3.4	19	54,151,400 - 54,181,495 (-)	RGD
Celera	19	51,327,207 - 51,357,149 (-)	RGD

Sequence:

show sequence

GGCCGGGCCGGGAGGGTCCCGGGTCCTGCGGCCCGGCCGGCTGGTGAGACTGTCGGGGCAGACG
CAGCGCCATGCGCGCCCCTCCTGCCAGGGCGCTGCTGCTGTTTCCGCGCCGGGGCCCTGCTGTG
CGAGCTTGGGCCCCGGCCGTCTCCTCTCGGACATGGTTGGCTTCTGAGTGGACTCCGCTCGTAC
GCGCGTGGACCTCTCTGATCCACGAGCCGAGCCCGGGCCTCCGCTTTCCCGTGCCCCTTTCGGG
GCTGCCTGGCGGCGTGGGACGGTGGGCCACCTCCTCGGGGATCCGCAGGTGTTGGGTGCTGGCA
GGACCCCGCGCCGCGCATCCCCTGTTCGCCAGGCTCCAGGGAGCAGCGGCCACCGGTGTGCGAG
ACCTTGGGAACGACTCGCAGCGGCGGCCCGCGACGACCGGGCGCTCAGAAGTGTGGAAGCTCCT
GGGGTTGGTGCGCCCGGAGCGCGGGAGACTGTCAGCTGCGGTTGGCTTTCTTGCCGTGTCCAGT
GTCATCACCATGTCGGCCCCCTTCTTCCTGGGGAAGATCATTGATGTCATCTACACCAACCCAA
CCGAGGACTTTGGCGACAGCCTGACTCGCCTCTGTGCTGGGCTCACCTGTGTGTTCCTGTGTGG
CGCTGCCGCGAACAGCATCCGTGTCTACCTCATGCAGTCTTCAGGTCAGAGCATTGTGAACAGG
CTGCGCACCTCACTCTTCTCCTCCATTCTAAGGCAAGAGGTTGCCTTCTTTGACAAGACCCGCA
CGGGCGAGTTGATTAACCGCCTCTCTTCGGATACCGCACTCCTGGGCCACTCCGTGACCGAGAA
TCTCTCTGACGGGCTGAGGGCTGTGGCCCAGGCCTCGGTTGGTGTTGGCATGATGTTCTTTGTG
TCACCAAGTCTGGCCACCTTTGTTCTGAGTGTGGTGCCACCTATCTCTGTCCTCGCTGTGATTT
ACGGGCGATATCTACGGAAACTGTCCAAAGCCACACAGGACTCTTTGGCAGAAGCCACACAGCT
AGCTGAGGAGCGGATTGGAAACATAAGAACCATCCGAGCTTTTGGGAAGGAGATGACAGAAGTG
GAGAAGTACACCAGCCGAGTGGACCAGTTGCTGCAGCTGGCACGGAAGGAGGCCTTGGCACGAG
CCGGCTTCTTTGGAGCGGCTGGGCTCTCGGGAAACTTGATTGTGCTGTCTGTCCTGTACAAAGG
AGGCCTGTTGCTGGGCAGCACCCACATGACAGTGGGCGAGCTCTCTTCCTTCCTCATGTACGCT
TTCTGGGTCGGACTGAGCATCGGAGGTCTGAGTTCATTCTACTCCCAGCTGATGAAGGGCCTGG
GTGCTGGCGGGCGGCTCTGGGAGCTGCTGGAGAGACAACCACGGCTGCCTTTTAACGAGGGGAT
CGTGTTAGATGAGAAAACCTTCCAGGGCGCCCTGGAGTTCAGAAATGTGCATTTCACGTACCCT
GCTCGCCCGGAGGTGTCCGTGTTCCAGGATTTCAGTCTTTCCATCCCATCTGGATCTGTCACAG
CGCTGGTTGGCCCTAGTGGTTCTGGGAAATCAACGGTGGTCTCACTCCTGCTGCGGTTGTACGA
CCCCAGTTCTGGAACAGTCAGTCTTGATGGCCATGACATTCGTCAGCTAAACCCCGTCTGGCTG
AGATCCAAGATTGGGACAGTAAGTCAGGAGCCAGTCCTGTTCTCCTGCTCTGTTGCTGAAAACA
TTGCCTATGGTGCTGACAACCTCTCCTCGGTCACAGCCCGGCAGGTGGAGAGGGCCGCAGAAGT
GGCCAATGCTGCTGAGTTCATTCGTAGCTTCCCACAGGGCTTCGACACTGTGGTCGGGGAGAAG
GGTGTCCTCCTGTCTGGTGGGCAGAAGCAGAGGATCGCAATAGCCAGAGCTCTGCTGAAGAACC
CCAAAATTCTTCTCCTCGATGAAGCAACCAGCGCACTGGATGCCGAAAACGAGCACCTGGTCCA
GGAGGCGCTTGACCGGCTGATGGAGGGAAGAACCGTGTTGATCATAGCCCACCGCCTCTCCACC
ATTAAGAACGCCAATTTCGTTGCCGTCCTTAACCAAGGAAAGATCTGTGAACATGGGACACATG
AGGAGCTGCTTTTGAAGCCCAATGGGCTTTACAGAAAACTGATGAACAAGCAGAGTCTCCTGCT
ACATAACGGGGCAGAGCAGTTCCTGGAACCTGCACAGGCGTAGCCTGCCATCCAGCTCTCGGGT
AGCTGAGGCCGAAGGACTGGACTCCAGCATTTACTTATCAATACCCTGTCTAAAGACAGGGACA
AAGCAGCGGTCAGGGGTGGGCTGTCTGAGAGACCTTAAAGCCAAACAGCATTGGGGAACAGATC
CTAGAGGCTGAGTGAAGCCTGTGAGTACTTCGGTTGTTTGAAACATGCCTCTTTCCACGAAGAA
TGTACAAAATTGTTTTATGGGTGTACCTGTCCTCCCAGGCCTTTGTGCCGCTGTAAAATTGTAA
CTTTCTAAATGTCTAAGGCACTGACGTGACTGCAGGTTTCCAGTGTTTGCTGGCTGAGCGGAAC
ACCTCACCTCCTGTGCTTGCTGCCAGAGTTGAGCTGGTCTCAGGTGACAGCTTTAAAAAGGGAA
CTGGAAACTAAATGCCTAACCAGTTTAAGCCAGTTTCCTAATCACTGGGGCACCTACCTGGGCC
ACTGAGGGAAAGTTTGCCTTTTCTGTCCCCTTCATCTTCAGGTGTCGGAATTCTGGGACACTAC
AGGCCGTCCGTACCTGTCAGAATGTGCAGTGTCCCCATCTGGGTACTGGAGAGCCTGATGTATT
TGCCAAAGGTAGAAATCCCGTTCTGTGAGCTGGAAAGCTTCTGTTTTTATCACTTCCTCGTTCT
TTGACTCCTTTTGAGAAGCAAGGTACAAACAACCAGGTATTACCAACAGAGGTGAATGAAAATC
CATTTCACATTCGTTGAAGCGTGTATTTTGAGAAAAAATACCCATTTTAAATATGTAACTCACA
GGTATATTGTAGTTTTATATTTTAAATTTTTATTAATGAGGCCGAATCTGAATAATAGAATTTT
CAGACTTGAGTACGGTGGCTCTTGCAGAAGCAAGGCAACAAAAGGAACGTCATCCTTTGGAAAG
CTTCAGAACTAAGACACGTTGTCCTGCTTCCATTACGCTAAGTCCTACCACCCTCCGAAGTCGA
CCTGTAGTGGCGGCGAGTGTGGCTGCCCTGCCAAGCACAAGTGAGTCTTTAACAGAGTGCCAAG
ACCAGGAGGCGGAACAGTGCTGGGCCTGGGGGAATGAGGCTCCTGGATTGTCTATCCTAGGTTT
AGACATGGCTCCTGTGAAGGAAAAACCTAGACCCAAGAGTGAAATTGTTGCAGCATCCAGTTCA
TGTTGAAGATTTCAGCACTCATGAAATAAGTGTTCTGGTTTCAAAAAAAAAAAAAAAAAAAAAA
AAAA

hide sequence

RefSeq Acc Id:

XM_039097899 ⟹ XP_038953827

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	19	68,858,062 - 68,881,689 (-)	NCBI
mRatBN7.2	19	51,960,609 - 51,982,907 (-)	NCBI

RefSeq Acc Id:

XM_063278167 ⟹ XP_063134237

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	19	68,855,627 - 68,881,689 (-)	NCBI

RefSeq Acc Id:

XM_063278168 ⟹ XP_063134238

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	19	68,860,763 - 68,881,689 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001012166	(Get FASTA)	NCBI Sequence Viewer
	XP_038953827	(Get FASTA)	NCBI Sequence Viewer
	XP_063134237	(Get FASTA)	NCBI Sequence Viewer
	XP_063134238	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH89900	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000024232
	ENSRNOP00000024232.3
	ENSRNOP00000096653.1

RefSeq Acc Id:

NP_001012166 ⟸ NM_001012166

- UniProtKB:

Q5FVL8 (UniProtKB/TrEMBL), A0A8I6ATQ1 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MRAPPARALLLFPRRGPAVRAWAPAVSSRTWLASEWTPLVRAWTSLIHEPSPGLRFPVPLSGLP
GGVGRWATSSGIRRCWVLAGPRAAHPLFARLQGAAATGVRDLGNDSQRRPATTGRSEVWKLLGL
VRPERGRLSAAVGFLAVSSVITMSAPFFLGKIIDVIYTNPTEDFGDSLTRLCAGLTCVFLCGAA
ANSIRVYLMQSSGQSIVNRLRTSLFSSILRQEVAFFDKTRTGELINRLSSDTALLGHSVTENLS
DGLRAVAQASVGVGMMFFVSPSLATFVLSVVPPISVLAVIYGRYLRKLSKATQDSLAEATQLAE
ERIGNIRTIRAFGKEMTEVEKYTSRVDQLLQLARKEALARAGFFGAAGLSGNLIVLSVLYKGGL
LLGSTHMTVGELSSFLMYAFWVGLSIGGLSSFYSQLMKGLGAGGRLWELLERQPRLPFNEGIVL
DEKTFQGALEFRNVHFTYPARPEVSVFQDFSLSIPSGSVTALVGPSGSGKSTVVSLLLRLYDPS
SGTVSLDGHDIRQLNPVWLRSKIGTVSQEPVLFSCSVAENIAYGADNLSSVTARQVERAAEVAN
AAEFIRSFPQGFDTVVGEKGVLLSGGQKQRIAIARALLKNPKILLLDEATSALDAENEHLVQEA
LDRLMEGRTVLIIAHRLSTIKNANFVAVLNQGKICEHGTHEELLLKPNGLYRKLMNKQSLLLHN
GAEQFLEPAQA

hide sequence

Ensembl Acc Id:

ENSRNOP00000024232 ⟸ ENSRNOT00000024232

RefSeq Acc Id:	XP_038953827 ⟸ XM_039097899
- Peptide Label:	isoform X2

Ensembl Acc Id:

ENSRNOP00000096653 ⟸ ENSRNOT00000113091

RefSeq Acc Id:	XP_063134237 ⟸ XM_063278167
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_063134238 ⟸ XM_063278168
- Peptide Label:	isoform X3

Protein Domains

ABC transmembrane type-1 ABC transporter

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5FVL8-F1-model_v2	AlphaFold	Q5FVL8	1-715	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13701232

Promoter ID:

EPDNEW_R11756

Type:

multiple initiation site

Name:

Abcb10_1

Description:

ATP binding cassette subfamily B member 10

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	19	56,772,869 - 56,772,929	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1311222	AgrOrtholog
BioCyc Gene	G2FUF-5259	BioCyc
Ensembl Genes	ENSRNOG00000017993	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000024232	ENTREZGENE
	ENSRNOT00000024232.6	UniProtKB/TrEMBL
	ENSRNOT00000113091.2	UniProtKB/TrEMBL
Gene3D-CATH	1.20.1560.10	UniProtKB/TrEMBL
	3.40.50.300	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7383307	IMAGE-MGC_LOAD
InterPro	ABC1_TM_sf	UniProtKB/TrEMBL
	ABC_transporter-like	UniProtKB/TrEMBL
	ABC_transporter_CS	UniProtKB/TrEMBL
	ABC_transptrTM_dom_typ1	UniProtKB/TrEMBL
	ATPase_AAA+_core	UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/TrEMBL
	Type_I_exporter	UniProtKB/TrEMBL
KEGG Report	rno:361439	UniProtKB/TrEMBL
MGC_CLONE	MGC:109142	IMAGE-MGC_LOAD
NCBI Gene	361439	ENTREZGENE
PANTHER	ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL	UniProtKB/TrEMBL
	ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL	UniProtKB/TrEMBL
Pfam	ABC_membrane	UniProtKB/TrEMBL
	ABC_tran	UniProtKB/TrEMBL
PharmGKB	ABCB10	RGD
PhenoGen	Abcb10	PhenoGen
PIRSF	ABC_prm/ATPase_B	UniProtKB/TrEMBL
PROSITE	ABC_TM1F	UniProtKB/TrEMBL
	ABC_TRANSPORTER_1	UniProtKB/TrEMBL
	ABC_TRANSPORTER_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000017993	RatGTEx
SMART	AAA	UniProtKB/TrEMBL
Superfamily-SCOP	ABC_TM_1	UniProtKB/TrEMBL
	SSF52540	UniProtKB/TrEMBL
UniProt	A0A8I6ATQ1	ENTREZGENE, UniProtKB/TrEMBL
	Q5FVL8	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-12-09	Abcb10	ATP binding cassette subfamily B member 10	Abcb10	ATP-binding cassette, subfamily B (MDR/TAP), member 10	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2010-11-16	Abcb10	ATP-binding cassette, subfamily B (MDR/TAP), member 10	Abcb10	ATP-binding cassette, sub-family B (MDR/TAP), member 10	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	Abcb10	ATP-binding cassette, sub-family B (MDR/TAP), member 10	Abcb10_predicted	ATP-binding cassette, sub-family B (MDR/TAP), member 10 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Abcb10_predicted	ATP-binding cassette, sub-family B (MDR/TAP), member 10 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Send us a Message

Imported Disease Annotations - CTD