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Gene: Rbm17 (RNA binding motif protein 17) Rattus norvegicus

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Symbol:

Rbm17

Name:

RNA binding motif protein 17

RGD ID:

1311208

Description:

Predicted to enable RNA binding activity. Predicted to be involved in alternative mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of protein-containing complex. Orthologous to human RBM17 (RNA binding motif protein 17); PARTICIPATES IN spliceosome pathway; INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC291295; splicing factor 45

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	RBM17 (RNA binding motif protein 17)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Rbm17 (RNA binding motif protein 17)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Rbm17 (RNA binding motif protein 17)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	RBM17 (RNA binding motif protein 17)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	RBM17 (RNA binding motif protein 17)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Rbm17 (RNA binding motif protein 17)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	RBM17 (RNA binding motif protein 17)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	RBM17 (RNA binding motif protein 17)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Rbm17 (RNA binding motif protein 17)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Rbm17 (RNA binding motif protein 17)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	RBM17 (RNA binding motif protein 17)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Rbm17 (RNA binding motif protein 17)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	rbm17 (RNA binding motif protein 17)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	rbm-17	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Spf45	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	rbm17	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	17	71,846,941 - 71,863,834 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	17	71,846,916 - 71,864,431 (+)	Ensembl				GRCr8
mRatBN7.2	17	66,937,140 - 66,954,034 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	17	66,937,140 - 66,954,014 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	17	70,422,794 - 70,439,754 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	17	74,251,622 - 74,268,582 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	17	68,294,616 - 68,311,577 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	17	70,586,345 - 70,603,289 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	17	70,586,394 - 70,603,267 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	17	72,288,967 - 72,305,900 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	17	78,139,912 - 78,156,805 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	17	66,441,566 - 66,458,459 (+)	NCBI		Celera
RGSC_v3.1	17	78,150,744 - 78,167,631 (+)	NCBI
Cytogenetic Map	17	q12.2	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Spinocerebellar Ataxias (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

1,2-dimethylhydrazine (ISO)

1-chloro-2,4-dinitrobenzene (ISO)

17alpha-ethynylestradiol (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-diaminodiphenylmethane (ISO)

4-(ethoxymethylene)-2-phenyloxazol-5-one (ISO)

antirheumatic drug (ISO)

aristolochic acid A (ISO)

Aroclor 1254 (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (EXP,ISO)

Bisphenol A diglycidyl ether (ISO)

bisphenol AF (ISO)

Brodifacoum (EXP)

cadmium dichloride (EXP)

caffeine (ISO)

cannabidiol (ISO)

carboplatin (ISO)

chlorpyrifos (ISO)

cisplatin (ISO)

coumarin (ISO)

deoxynivalenol (ISO)

dexamethasone (ISO)

diarsenic trioxide (ISO)

Dibutyl phosphate (ISO)

doxorubicin (ISO)

enzyme inhibitor (ISO)

etoposide (ISO)

fenvalerate (EXP)

flutamide (EXP)

folic acid (ISO)

FR900359 (ISO)

gemcitabine (ISO)

genistein (ISO)

indometacin (ISO)

ivermectin (ISO)

lipopolysaccharide (ISO)

LY 117018 (ISO)

menadione (ISO)

mitoxantrone (ISO)

nickel sulfate (ISO)

nitrates (ISO)

Nivalenol (ISO)

paracetamol (ISO)

pemetrexed (ISO)

phorone (EXP)

resveratrol (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

sodium arsenite (ISO)

tamoxifen (ISO)

temozolomide (ISO)

tetrachloromethane (EXP)

thioacetamide (EXP)

valproic acid (ISO)

vinclozolin (EXP)

vincristine (ISO)

vinorelbine (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

alternative mRNA splicing, via spliceosome (IBA,IEA,ISO)

mRNA cis splicing, via spliceosome (IEA)

mRNA processing (IEA)

mRNA splicing, via spliceosome (IEA)

RNA splicing (IEA)

RNA splicing, via transesterification reactions (IEA)

Cellular Component

nucleoplasm (IEA,ISO)

nucleus (IEA,ISO)

protein-containing complex (IEA,ISO)

spliceosomal complex (IEA)

Molecular Function

nucleic acid binding (IEA)

protein binding (ISO)

RNA binding (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

spliceosome pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
4.	GOA pipeline	RGD automated data pipeline
5.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
7.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:17589525	PMID:18337722	PMID:25931508

Genomics

Comparative Map Data

Rbm17
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	17	71,846,941 - 71,863,834 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	17	71,846,916 - 71,864,431 (+)	Ensembl				GRCr8
mRatBN7.2	17	66,937,140 - 66,954,034 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	17	66,937,140 - 66,954,014 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	17	70,422,794 - 70,439,754 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	17	74,251,622 - 74,268,582 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	17	68,294,616 - 68,311,577 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	17	70,586,345 - 70,603,289 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	17	70,586,394 - 70,603,267 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	17	72,288,967 - 72,305,900 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	17	78,139,912 - 78,156,805 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	17	66,441,566 - 66,458,459 (+)	NCBI		Celera
RGSC_v3.1	17	78,150,744 - 78,167,631 (+)	NCBI
Cytogenetic Map	17	q12.2	NCBI

RBM17
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	10	6,089,034 - 6,117,447 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	10	6,086,898 - 6,117,457 (+)	Ensembl			hg38	GRCh38
GRCh37	10	6,130,997 - 6,159,410 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	6,171,013 - 6,198,849 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	10	6,171,012 - 6,198,845	NCBI
Celera	10	6,060,328 - 6,088,794 (+)	NCBI		Celera
Cytogenetic Map	10	p15.1	NCBI
HuRef	10	6,057,262 - 6,085,729 (+)	NCBI		HuRef
CHM1_1	10	6,131,060 - 6,159,561 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	10	6,089,199 - 6,117,608 (+)	NCBI		T2T-CHM13v2.0

Rbm17
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	11,590,250 - 11,608,061 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	11,590,248 - 11,608,964 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	2	11,585,439 - 11,603,199 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	11,585,437 - 11,604,153 (-)	Ensembl			mm10	GRCm38
MGSCv37	2	11,507,066 - 11,524,826 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	2	11,503,292 - 11,521,052 (-)	NCBI		MGSCv36	mm8
Celera	2	11,504,598 - 11,522,403 (-)	NCBI		Celera
Cytogenetic Map	2	A1	NCBI
cM Map	2	8.85	NCBI

Rbm17
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955421	22,732,757 - 22,746,014 (+)	Ensembl
ChiLan1.0	NW_004955421	22,732,757 - 22,745,926 (+)	NCBI	ChiLan1.0	ChiLan1.0

RBM17
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	8	18,642,158 - 18,670,043 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	10	18,647,503 - 18,675,366 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	10	6,129,708 - 6,157,513 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	10	6,120,488 - 6,140,085 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	10	6,120,488 - 6,140,085 (+)	Ensembl			panPan2	panpan1.1

RBM17
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	29,828,720 - 29,853,922 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	29,829,210 - 29,853,841 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	26,859,360 - 26,884,558 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	30,209,817 - 30,235,027 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	30,209,024 - 30,234,985 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	27,306,882 - 27,332,090 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	28,142,934 - 28,168,134 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	28,862,842 - 28,888,059 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Rbm17
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	32,292,267 - 32,312,839 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936484	8,457,462 - 8,478,309 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936484	8,457,469 - 8,478,030 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RBM17
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	10	64,885,870 - 64,908,963 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	10	64,886,433 - 64,909,006 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	10	70,943,098 - 70,964,954 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RBM17
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	9	6,213,477 - 6,240,945 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	9	6,221,570 - 6,239,678 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666051	11,517,551 - 11,549,925 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rbm17
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624775	1,041,348 - 1,071,194 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624775	1,041,666 - 1,067,195 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Rbm17
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	14	17,618,080 - 17,635,544 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Rbm17
141 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	141
Count of miRNA genes:	117
Interacting mature miRNAs:	125
Transcripts:	ENSRNOT00000025550
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
70210	Cm15	Cardiac mass QTL 15	6.5		heart right ventricle mass (VT:0007033)	heart right ventricle wet weight (CMO:0000072)	17	30066472	75066472	Rat
152023626	Bp403	Blood pressure QTL 403	3.86		arterial blood pressure trait (VT:2000000)		17	24136127	84432719	Rat
2301412	Kidm40	Kidney mass QTL 40		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	17	42388164	87388164	Rat
631502	Cm26	Cardiac mass QTL 26	3.71		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	17	70613502	86062352	Rat
1354588	Bvd4	Brain ventricular dilatation QTL 4	5.31	0.001	brain ventricle morphology trait (VT:0000822)	hydrocephalus severity score (CMO:0001881)	17	58194064	87388164	Rat
9590107	Sffal7	Serum free fatty acids level QTL 7	4.81	0.001	blood free fatty acid amount (VT:0001553)	plasma free fatty acids level (CMO:0000546)	17	33104645	78104645	Rat
1354654	Spl7	Serum phospholipid level QTL 7	5.5		blood phospholipid amount (VT:0006084)	blood phospholipid level (CMO:0001169)	17	38031354	83031354	Rat
2317038	Ginf3	Gastrointestinal inflammation QTL 3	2.89	0.005	liver integrity trait (VT:0010547)	liver granuloma severity score (CMO:0002157)	17	54829503	93515804	Rat
1598871	Memor5	Memory QTL 5	5.3		exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	17	40968017	89341781	Rat
1581512	Cm55	Cardiac mass QTL 55	2.8	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	17	27233445	83975845	Rat
1354629	Scl31	Serum cholesterol level QTL 31	4.1		blood cholesterol amount (VT:0000180)	blood total cholesterol level (CMO:0000051)	17	38031354	83031354	Rat
1600398	Edcs5	Endometrial carcinoma susceptibility QTL 5	2.2		uterus morphology trait (VT:0001120)	percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)	17	35446949	75762341	Rat
152025238	Slep14	Serum leptin concentration QTL 14	4.62		blood leptin amount (VT:0005667)		17	24390595	84432719	Rat
1354638	Insul1	Insulin level QTL 1	4.8		blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	17	38031354	83031354	Rat
61466	Niddm12	Non-insulin dependent diabetes mellitus QTL 12	3.2	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	17	65154872	93515804	Rat
1354635	Bp245	Blood pressure QTL 245	6		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	17	38031354	83031354	Rat
8552928	Pigfal9	Plasma insulin-like growth factor 1 level QTL 9	9		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	17	33104645	78104645	Rat
12904736	Cm121	Cardiac mass QTL 121		0.043	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	17	42388164	87388164	Rat
1300148	Bp192	Blood pressure QTL 192	3.47		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	17	46050126	91050126	Rat
4889891	Eae32	Experimental allergic encephalomyelitis QTL 32	4.8	0.0002	nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis severity score (CMO:0001419)	17	27233445	72233445	Rat
4889894	Eae33	Experimental allergic encephalomyelitis QTL 33	5.2	0.0001	nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis severity score (CMO:0001419)	17	55604597	93006569	Rat
2324621	Coatc5	Coat color QTL 5			coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	17	42654895	87654895	Rat
1354619	Bp242	Blood pressure QTL 242	6.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	17	37687877	82687877	Rat
1300131	Bp193	Blood pressure QTL 193	3.3		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	17	68550040	93515804	Rat
7488963	Bp369	Blood pressure QTL 369		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	17	63697147	82818564	Rat
1300129	Rf25	Renal function QTL 25	3.03		blood creatinine amount (VT:0005328)	creatinine clearance (CMO:0000765)	17	41062352	86062352	Rat
152023740	Bp406	Blood pressure QTL 406	6.06		arterial blood pressure trait (VT:2000000)		17	24136127	84432719	Rat
1354663	Bvd5	Brain ventricular dilatation QTL 5	3.51	0.001	brain ventricle morphology trait (VT:0000822)	hydrocephalus severity score (CMO:0001881)	17	32199534	86201342	Rat
152023737	Bp405	Blood pressure QTL 405	5.06		arterial blood pressure trait (VT:2000000)			24136127	84432719	Rat
152023736	Bp404	Blood pressure QTL 404	3.78		arterial blood pressure trait (VT:2000000)		17	24136127	84432719	Rat
724528	Uae4	Urinary albumin excretion QTL 4	4.9	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	17	36045537	81045537	Rat
2302365	Gluco40	Glucose level QTL 40	4.79		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	17	64569820	86954580	Rat

Markers in Region

AI385205

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	17	66,952,439 - 66,953,772 (+)	MAPPER	mRatBN7.2
Rnor_6.0	17	70,601,693 - 70,603,025	NCBI	Rnor6.0
Rnor_5.0	17	72,304,304 - 72,305,636	UniSTS	Rnor5.0
RGSC_v3.4	17	78,155,211 - 78,156,543	UniSTS	RGSC3.4
Celera	17	66,456,865 - 66,458,197	UniSTS
Cytogenetic Map	17	q12.3	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001013058	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006254205	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC141172	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC079248	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473990	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ230702	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000017	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000025550 ⟹ ENSRNOP00000025550

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	17	71,846,916 - 71,864,431 (+)	Ensembl
mRatBN7.2 Ensembl	17	66,937,140 - 66,954,014 (+)	Ensembl
Rnor_6.0 Ensembl	17	70,586,394 - 70,603,267 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000101458 ⟹ ENSRNOP00000083361

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	17	66,937,140 - 66,953,136 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000106718 ⟹ ENSRNOP00000083907

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	17	71,847,181 - 71,863,654 (+)	Ensembl
mRatBN7.2 Ensembl	17	66,937,140 - 66,953,854 (+)	Ensembl

RefSeq Acc Id:

NM_001013058 ⟹ NP_001013076

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	17	71,846,941 - 71,863,834 (+)	NCBI
mRatBN7.2	17	66,937,140 - 66,954,034 (+)	NCBI
Rnor_6.0	17	70,586,394 - 70,603,287 (+)	NCBI
Rnor_5.0	17	72,288,967 - 72,305,900 (+)	NCBI
RGSC_v3.4	17	78,139,912 - 78,156,805 (+)	RGD
Celera	17	66,441,566 - 66,458,459 (+)	RGD

Sequence:

show sequence

GGTGGAGGCTCGGTGCTGCGGCGGGCTCCGGCGGTGGGCGGGCTTCCGCGCAGGGCGGCCGGGC
TCGGCGCTGCCGCCGCCGTGGCCCATGGGCACAGTCGTCTCGGAAGGCCGGTATTAAACCAAAA
AGATGTCCCTATATGATGACCTGGGAGTGGAGACCAGTGACTCAAAAACTGAAGGCTGGTCCAA
AAACTTCAAGCTTCTGCAGTCCCAGCTCCAGGTGAAGAAGGCAGCTCTCACTCAAGCCAAGAGC
CAAAGGACAAAGCAAAGTACAGTCCTCGCTCCAGTCATCGACCTGAAGCGAGGAGGCTCCTCAG
ATGACCGACAGATCGTAGACACGCCACCTCATGTGGCAGCTGGGCTGAAGGACCCTGTGCCCAG
TGGGTTCTCTGCAGGGGAAGTCCTGATCCCCTTGGCTGATGAATATGACCCAATGTTTCCTAAC
GACTATGAGAAAGTGGTGAAGCGCCAGAGAGAAGAGCGGCAGAGGCAGCGGGAGCTGGAAAGAC
AGAAGGAAATAGAGGAAAGAGAAAAGAGGCGTAAAGACAGACATGAAGCCAGTGGGTTTTCAAG
ACGCCCAGACCCGGACTCGGATGAGGATGAAGATTATGAGCGAGAGCGGAGGAAAAGAAGTATG
GGGGGAGCTGCCATCGCCCCACCGACCTCTCTGGTAGAGAAAGACAAAGAGTTACCCCGAGATT
TTCCCTATGAAGAGGACTCAAGACCTCGATCACAGTCTTCCAAAGCTGCTATTCCTCCCCCAGT
GTATGAGGAGCCGGACAGACCAAGGTCTCCAACCGGCCCCAGCAACTCCTTCCTCGCTAACATG
GGTGGCACCGTGGCTCATAAGATCATGCAGAAGTATGGCTTCCGGGAAGGTCAGGGGCTGGGGA
AACATGAGCAAGGGCTAAGCACTGCATTGTCCGTGGAGAAGACCAGCAAGCGTGGCGGCAAGAT
CATTGTTGGTGACGCCACAGAGAAGGGCGAGTCTCAGGATGCATCCAAGAAGTCGGATTCAAAT
CCATTAACTGAAATTCTTAAGTGCCCTACTAAAGTGGTCTTGCTGAGGAACATGGTCGGTGCAG
GAGAGGTCGATGAAGACTTGGAAGTTGAAACCAAGGAAGAATGTGAAAAATATGGCAAAGTTGG
GAAATGTGTGATATTTGAGATTCCTGGTGCCCCTGATGATGAAGCAGTACGGATATTTCTAGAA
TTTGAGAGAGTCGAATCGGCAATTAAAGCTGTTGTCGATCTGAATGGGAGGTATTTTGGTGGAC
GGGTGGTTAAAGCCTGTTTCTACAATTTGGATAAATTCAGGGTCTTGGATCTAGCAGAGCAAGT
GTGATTGTAACTTAAAGTCACCTCCTTGATCCTTACACGAGCTGCAGACTGAGCAATGGCACAG
GCGTCAGCCTCCATGGCTGCTGGACACTGAAACTCTTGGATGGACTTCTAAGATATATGTTGAT
GGATCCCTTTTTTATTTTGTGTTTTTTTAATATAGTATAAAAATCCTTTAAAAATCAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006254205 ⟹ XP_006254267

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	17	71,846,973 - 71,863,834 (+)	NCBI
mRatBN7.2	17	66,937,172 - 66,954,034 (+)	NCBI
Rnor_6.0	17	70,586,345 - 70,603,289 (+)	NCBI
Rnor_5.0	17	72,288,967 - 72,305,900 (+)	NCBI

Sequence:

show sequence

CGGCAGCCCCCGCTCTCCTACCCCGCGCGGTGCATCACTTTGCGGACTCGGTGGAGGCTCGGTG
CTGCGGCGGGCTCCGGCGGTGGGCGGGCTTCCGCGCAGGGCGGCCGGGCTCGGCGCTGCCGCCG
CCGTGGCCCATGGGCACAGTCGTCTCGGAAGGCCGGGTGAGTGGCGCCGCGGCGGCCCTGGCAG
GCGGTTCCGATCTGGAACGGAGACTCGGTATTAAACCAAAAAGATGTCCCTATATGATGACCTG
GGAGTGGAGACCAGTGACTCAAAAACTGAAGGCTGGTCCAAAAACTTCAAGCTTCTGCAGTCCC
AGCTCCAGGTGAAGAAGGCAGCTCTCACTCAAGCCAAGAGCCAAAGGACAAAGCAAAGTACAGT
CCTCGCTCCAGTCATCGACCTGAAGCGAGGAGGCTCCTCAGATGACCGACAGATCGTAGACACG
CCACCTCATGTGGCAGCTGGGCTGAAGGACCCTGTGCCCAGTGGGTTCTCTGCAGGGGAAGTCC
TGATCCCCTTGGCTGATGAATATGACCCAATGTTTCCTAACGACTATGAGAAAGTGGTGAAGCG
CCAGAGAGAAGAGCGGCAGAGGCAGCGGGAGCTGGAAAGACAGAAGGAAATAGAGGAAAGAGAA
AAGAGGCGTAAAGACAGACATGAAGCCAGTGGGTTTTCAAGACGCCCAGACCCGGACTCGGATG
AGGATGAAGATTATGAGCGAGAGCGGAGGAAAAGAAGTATGGGGGGAGCTGCCATCGCCCCACC
GACCTCTCTGGTAGAGAAAGACAAAGAGTTACCCCGAGATTTTCCCTATGAAGAGGACTCAAGA
CCTCGATCACAGTCTTCCAAAGCTGCTATTCCTCCCCCAGTGTATGAGGAGCCGGACAGACCAA
GGTCTCCAACCGGCCCCAGCAACTCCTTCCTCGCTAACATGGGTGGCACCGTGGCTCATAAGAT
CATGCAGAAGTATGGCTTCCGGGAAGGTCAGGGGCTGGGGAAACATGAGCAAGGGCTAAGCACT
GCATTGTCCGTGGAGAAGACCAGCAAGCGTGGCGGCAAGATCATTGTTGGTGACGCCACAGAGA
AGGGCGAGTCTCAGGATGCATCCAAGAAGTCGGATTCAAATCCATTAACTGAAATTCTTAAGTG
CCCTACTAAAGTGGTCTTGCTGAGGAACATGGTCGGTGCAGGAGAGGTCGATGAAGACTTGGAA
GTTGAAACCAAGGAAGAATGTGAAAAATATGGCAAAGTTGGGAAATGTGTGATATTTGAGATTC
CTGGTGCCCCTGATGATGAAGCAGTACGGATATTTCTAGAATTTGAGAGAGTCGAATCGGCAAT
TAAAGCTGTTGTCGATCTGAATGGGAGGTATTTTGGTGGACGGGTGGTTAAAGCCTGTTTCTAC
AATTTGGATAAATTCAGGGTCTTGGATCTAGCAGAGCAAGTGTGATTGTAACTTAAAGTCACCT
CCTTGATCCTTACACGAGCTGCAGACTGAGCAATGGCACAGGCGTCAGCCTCCATGGCTGCTGG
ACACTGAAACTCTTGGATGGACTTCTAAGATATATGTTGATGGATCCCTTTTTTATTTTGTGTT
TTTTTAATATAGTATAAAAATCCTTTAAAAATCTG

hide sequence

Protein Sequences


Protein RefSeqs	NP_001013076	(Get FASTA)	NCBI Sequence Viewer
	XP_006254267	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH79248	(Get FASTA)	NCBI Sequence Viewer
	EDL78598	(Get FASTA)	NCBI Sequence Viewer
	EDL78599	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000025550
	ENSRNOP00000025550.3
	ENSRNOP00000083907
	ENSRNOP00000083907.1

RefSeq Acc Id:

NP_001013076 ⟸ NM_001013058

- UniProtKB:

Q6AY02 (UniProtKB/TrEMBL), A0A8I5ZW65 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSLYDDLGVETSDSKTEGWSKNFKLLQSQLQVKKAALTQAKSQRTKQSTVLAPVIDLKRGGSSD
DRQIVDTPPHVAAGLKDPVPSGFSAGEVLIPLADEYDPMFPNDYEKVVKRQREERQRQRELERQ
KEIEEREKRRKDRHEASGFSRRPDPDSDEDEDYERERRKRSMGGAAIAPPTSLVEKDKELPRDF
PYEEDSRPRSQSSKAAIPPPVYEEPDRPRSPTGPSNSFLANMGGTVAHKIMQKYGFREGQGLGK
HEQGLSTALSVEKTSKRGGKIIVGDATEKGESQDASKKSDSNPLTEILKCPTKVVLLRNMVGAG
EVDEDLEVETKEECEKYGKVGKCVIFEIPGAPDDEAVRIFLEFERVESAIKAVVDLNGRYFGGR
VVKACFYNLDKFRVLDLAEQV

hide sequence

RefSeq Acc Id:	XP_006254267 ⟸ XM_006254205
- Peptide Label:	isoform X1
- UniProtKB:	Q6AY02 (UniProtKB/TrEMBL), A0A8I5ZW65 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSLYDDLGVETSDSKTEGWSKNFKLLQSQLQVKKAALTQAKSQRTKQSTVLAPVIDLKRGGSSD DRQIVDTPPHVAAGLKDPVPSGFSAGEVLIPLADEYDPMFPNDYEKVVKRQREERQRQRELERQ KEIEEREKRRKDRHEASGFSRRPDPDSDEDEDYERERRKRSMGGAAIAPPTSLVEKDKELPRDF PYEEDSRPRSQSSKAAIPPPVYEEPDRPRSPTGPSNSFLANMGGTVAHKIMQKYGFREGQGLGK HEQGLSTALSVEKTSKRGGKIIVGDATEKGESQDASKKSDSNPLTEILKCPTKVVLLRNMVGAG EVDEDLEVETKEECEKYGKVGKCVIFEIPGAPDDEAVRIFLEFERVESAIKAVVDLNGRYFGGR VVKACFYNLDKFRVLDLAEQV hide sequence

Ensembl Acc Id:

ENSRNOP00000025550 ⟸ ENSRNOT00000025550

Ensembl Acc Id:

ENSRNOP00000083907 ⟸ ENSRNOT00000106718

Ensembl Acc Id:

ENSRNOP00000083361 ⟸ ENSRNOT00000101458

Protein Domains

G-patch

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q6AY02-F1-model_v2	AlphaFold	Q6AY02	1-405	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13700556

Promoter ID:

EPDNEW_R11080

Type:

initiation region

Name:

Rbm17_1

Description:

RNA binding motif protein 17

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	17	70,586,381 - 70,586,441	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1311208	AgrOrtholog
BioCyc Gene	G2FUF-8797	BioCyc
Ensembl Genes	ENSRNOG00000018767	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000025550	ENTREZGENE
	ENSRNOT00000025550.8	UniProtKB/TrEMBL
	ENSRNOT00000106718	ENTREZGENE
	ENSRNOT00000106718.2	UniProtKB/TrEMBL
Gene3D-CATH	3.30.70.330	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7132972	IMAGE-MGC_LOAD
InterPro	G_patch	UniProtKB/TrEMBL
	Nucleotide-bd_a/b_plait_sf	UniProtKB/TrEMBL
	RBD_domain_sf	UniProtKB/TrEMBL
	RBM17	UniProtKB/TrEMBL
	RNA-recognition_dom1	UniProtKB/TrEMBL
	RRM_dom	UniProtKB/TrEMBL
	SPF45_RRM	UniProtKB/TrEMBL
KEGG Report	rno:291295	UniProtKB/TrEMBL
MGC_CLONE	MGC:94338	IMAGE-MGC_LOAD
NCBI Gene	291295	ENTREZGENE
PANTHER	PTHR13288	UniProtKB/TrEMBL
	SPLICING FACTOR 45	UniProtKB/TrEMBL
Pfam	G-patch	UniProtKB/TrEMBL
	RRM_1	UniProtKB/TrEMBL
PhenoGen	Rbm17	PhenoGen
PIRSF	Splicing_factor_SPF45	UniProtKB/TrEMBL
PROSITE	G_PATCH	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000018767	RatGTEx
SMART	G_patch	UniProtKB/TrEMBL
	RRM_1	UniProtKB/TrEMBL
Superfamily-SCOP	SSF54928	UniProtKB/TrEMBL
UniProt	A0A8I5ZW65	ENTREZGENE, UniProtKB/TrEMBL
	A6JLS1_RAT	UniProtKB/TrEMBL
	A6JLS2_RAT	UniProtKB/TrEMBL
	Q6AY02	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2005-12-06	Rbm17	RNA binding motif protein 17	Rbm17_predicted	RNA binding motif protein 17 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Rbm17_predicted	RNA binding motif protein 17 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - CTD

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - CTD

Imported Annotations - KEGG (archival)