Cda (cytidine deaminase) - Rat Genome Database

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Gene: Cda (cytidine deaminase) Rattus norvegicus
Analyze
Symbol: Cda
Name: cytidine deaminase
RGD ID: 1311101
Description: Predicted to enable several functions, including cytidine deaminase activity; protein homodimerization activity; and zinc ion binding activity. Involved in cellular response to external biotic stimulus. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Orthologous to human CDA (cytidine deaminase); PARTICIPATES IN beta-ureidopropionase deficiency pathway; capecitabine pharmacodynamics pathway; capecitabine pharmacokinetics pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',5,5'-tetrabromobisphenol A; 5-fluorouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: cytidine deaminase-like; LOC100909857; LOC362638
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85155,839,929 - 155,866,541 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5155,839,929 - 155,866,541 (-)EnsemblGRCr8
mRatBN7.25150,556,615 - 150,583,231 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5150,556,615 - 150,583,231 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5153,252,247 - 153,279,877 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05155,026,533 - 155,054,163 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05155,008,554 - 155,036,184 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05156,703,579 - 156,734,541 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5156,703,579 - 156,734,541 (-)Ensemblrn6Rnor6.0
Rnor_6.0 Ensembl5156,757,044 - 156,781,291 (-)Ensemblrn6Rnor6.0
Rnor_5.05160,452,101 - 160,482,729 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45157,117,303 - 157,143,989 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5148,950,060 - 148,976,672 (-)NCBICelera
RGSC_v3.15157,127,441 - 157,153,991 (-)NCBI
Cytogenetic Map5q36NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-diaminotoluene  (ISO)
2-hydroxypropanoic acid  (ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP)
3-methylcholanthrene  (ISO)
4-hydroxyphenyl retinamide  (ISO)
4-tert-Octylphenol  (ISO)
5'-Deoxy-5-fluorocytidine  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-fluorocytidine  (ISO)
5-fluorouracil  (EXP)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amiodarone  (ISO)
arsenite(3-)  (ISO)
Azoxymethane  (ISO)
benzo[a]pyrene  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
brequinar  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calciol  (ISO)
calcitriol  (ISO)
captan  (ISO)
carbon nanotube  (ISO)
celastrol  (ISO)
chlorambucil  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
copper(II) sulfate  (ISO)
crizotinib  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
Dibutyl phosphate  (ISO)
dichloroacetic acid  (ISO)
dioxygen  (EXP)
dorsomorphin  (ISO)
entinostat  (ISO)
epoxiconazole  (ISO)
fipronil  (EXP)
folic acid  (ISO)
folpet  (ISO)
formaldehyde  (ISO)
furan  (EXP)
gardiquimod  (ISO)
gemcitabine  (ISO)
genistein  (ISO)
gentamycin  (EXP)
gold atom  (ISO)
gold(0)  (ISO)
hydrogen peroxide  (ISO)
ifosfamide  (EXP)
inulin  (ISO)
isotretinoin  (ISO)
L-methionine  (ISO)
melphalan  (ISO)
methimazole  (EXP)
mitomycin C  (ISO)
oxaliplatin  (ISO)
p-tert-Amylphenol  (ISO)
paclitaxel  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
progesterone  (ISO)
protein kinase inhibitor  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
succimer  (ISO)
sulforaphane  (ISO)
tamoxifen  (ISO)
Tegafur  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
titanium dioxide  (ISO)
trichloroethene  (EXP)
triphenyl phosphate  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
cytosol  (IBA,IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Adenosine deaminase, 5'-nucleotidase, guanase and cytidine deaminase activities in gastric tissues from patients with gastric cancer. Durak I, etal., Cancer Lett. 1994 Sep 15;84(2):199-202. doi: 10.1016/0304-3835(94)90376-x.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Development of multidrug resistance due to multiple factors including P-glycoprotein overexpression under K-selection after MYC and HRAS oncogene activation. Nakamura Y, etal., Int J Cancer. 2006 May 15;118(10):2448-54.
6. Identification of new SNPs associated with severe toxicity to capecitabine. Pellicer M, etal., Pharmacol Res. 2017 Jun;120:133-137. doi: 10.1016/j.phrs.2017.03.021. Epub 2017 Mar 27.
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Pyrimidine nucleotide synthesis in rat liver after the administration of cycloheximide. Seifert J and Vacha J, Toxicology. 1978 May;10(1):29-38.
12. Pharmacokinetics of gemcitabine in Japanese cancer patients: the impact of a cytidine deaminase polymorphism. Sugiyama E, etal., J Clin Oncol. 2007 Jan 1;25(1):32-42.
13. Correlation of CDA, ERCC1, and XPD polymorphisms with response and survival in gemcitabine/cisplatin-treated advanced non-small cell lung cancer patients. Tibaldi C, etal., Clin Cancer Res. 2008 Mar 15;14(6):1797-803.
Additional References at PubMed
PMID:7923172   PMID:9596658   PMID:11591653   PMID:15689149   PMID:31515488  


Genomics

Comparative Map Data
Cda
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85155,839,929 - 155,866,541 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5155,839,929 - 155,866,541 (-)EnsemblGRCr8
mRatBN7.25150,556,615 - 150,583,231 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5150,556,615 - 150,583,231 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5153,252,247 - 153,279,877 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05155,026,533 - 155,054,163 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05155,008,554 - 155,036,184 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05156,703,579 - 156,734,541 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5156,703,579 - 156,734,541 (-)Ensemblrn6Rnor6.0
Rnor_6.0 Ensembl5156,757,044 - 156,781,291 (-)Ensemblrn6Rnor6.0
Rnor_5.05160,452,101 - 160,482,729 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45157,117,303 - 157,143,989 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5148,950,060 - 148,976,672 (-)NCBICelera
RGSC_v3.15157,127,441 - 157,153,991 (-)NCBI
Cytogenetic Map5q36NCBI
CDA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38120,589,097 - 20,618,903 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl120,588,932 - 20,618,908 (+)Ensemblhg38GRCh38
GRCh37120,915,590 - 20,945,396 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36120,788,031 - 20,817,988 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34120,660,836 - 20,690,702NCBI
Celera119,239,772 - 19,269,752 (+)NCBICelera
Cytogenetic Map1p36.12NCBI
HuRef119,161,467 - 19,190,528 (+)NCBIHuRef
CHM1_1121,025,824 - 21,055,781 (+)NCBICHM1_1
T2T-CHM13v2.0120,414,048 - 20,443,922 (+)NCBIT2T-CHM13v2.0
Cda
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394138,065,839 - 138,095,623 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4138,065,735 - 138,095,303 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm384138,338,528 - 138,368,311 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4138,338,424 - 138,367,992 (-)Ensemblmm10GRCm38
MGSCv374137,894,443 - 137,923,870 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv364137,610,604 - 137,640,031 (-)NCBIMGSCv36mm8
Celera4140,122,623 - 140,152,350 (-)NCBICelera
Cytogenetic Map4D3NCBI
cM Map470.17NCBI
Cda
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554521,132,049 - 1,156,565 (+)Ensembl
ChiLan1.0NW_0049554521,131,968 - 1,156,777 (+)NCBIChiLan1.0ChiLan1.0
CDA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21206,506,028 - 206,535,363 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11205,618,335 - 205,647,685 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0119,538,696 - 19,568,008 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1120,583,441 - 20,612,711 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl120,583,441 - 20,612,711 (+)EnsemblpanPan2panpan1.1
CDA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1278,305,328 - 78,327,229 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl278,304,726 - 78,327,247 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha274,819,639 - 74,841,500 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0278,872,416 - 78,894,283 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl278,870,359 - 78,894,541 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1275,690,869 - 75,712,919 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0276,702,707 - 76,724,560 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0277,706,391 - 77,728,271 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Cda
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505840,718,495 - 40,739,795 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364746,543,220 - 6,566,308 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364746,543,295 - 6,564,575 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl678,824,270 - 78,849,547 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1678,824,248 - 78,849,154 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2673,017,555 - 73,042,459 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CDA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120111,931,365 - 111,960,172 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20111,931,364 - 111,960,036 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660334,270,608 - 4,299,725 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cda
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247645,621,899 - 5,645,850 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247645,621,888 - 5,645,055 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Cda
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1119,853,407 - 19,880,552 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Cda
238 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:140
Count of miRNA genes:88
Interacting mature miRNAs:106
Transcripts:ENSRNOT00000021036, ENSRNOT00000075128
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5130249266172190305Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5116702075161702075Rat
1354583Despr3Despair related QTL34.980.0002locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)5132930505172190305Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5141212838172190305Rat
1300119Bp180Blood pressure QTL 1803.82arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5149642129171146538Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)599905133172190305Rat
70156Niddm30Non-insulin dependent diabetes mellitus QTL 303.98blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)5134369218156289444Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5133789363172190305Rat
1331803Rf32Renal function QTL 322.798kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)5134369199172190305Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)565089051166764498Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5136631198172190305Rat
7207486Bss109Bone structure and strength QTL 109femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)5112142946157142946Rat
7207481Bss106Bone structure and strength QTL 1067.9femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5112142946157142946Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5133081618172190305Rat
631263Cm24Cardiac mass QTL 243.5heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)5149805999162987697Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)551657967166600247Rat
631505Bp103Blood pressure QTL 1033.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5138002522170842766Rat
1581505Rf54Renal function QTL 54kidney physiology trait (VT:0002136)kidney 20-HETE level (CMO:0001854)5133270647172190305Rat
1549838Bss4Bone structure and strength QTL 49.2femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)5112142946157142946Rat
2317753Glom24Glomerulus QTL 243.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)5141764300172190305Rat
1331721Bp210Blood pressure QTL 2103.413arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5148093485172129029Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5133789363172190305Rat
1581510Cm54Cardiac mass QTL 543.40.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)5125969677172190305Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555124766172190305Rat
2317056Wbc3White blood cell count QTL 32.510.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)5111236572156236572Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5131708216172190305Rat
1598847Cm62Cardiac mass QTL 623.4heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5114131300159131300Rat
2293642Bss37Bone structure and strength QTL 374.640.0001femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5125969677156302135Rat
2313096Bmd78Bone mineral density QTL 783.10.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)5149661912166600247Rat
8694441Bw169Body weight QTL 16917.610.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)5116702075161702075Rat
7207488Bss110Bone structure and strength QTL 18.4femur strength trait (VT:0010010)femur stiffness (CMO:0001674)5112142946157142946Rat
7207491Bss112Bone structure and strength QTL 1127femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)5112142946157142946Rat
8694389Bw160Body weight QTL 1606.170.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)5116702075161702075Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)574335621156302135Rat
8694198Abfw3Abdominal fat weight QTL 316.130.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)5116702075161702075Rat
1298089Scl14Serum cholesterol level QTL 145.80.0004blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5114131300159131300Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5133081618172190305Rat

Markers in Region
RH141036  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25150,556,910 - 150,557,109 (+)MAPPERmRatBN7.2
Rnor_6.05156,756,874 - 156,757,072NCBIRnor6.0
Rnor_6.05156,703,875 - 156,704,073NCBIRnor6.0
Rnor_5.05160,505,087 - 160,505,285UniSTSRnor5.0
Rnor_5.05160,452,397 - 160,452,595UniSTSRnor5.0
RGSC_v3.45157,117,599 - 157,117,797UniSTSRGSC3.4
Celera5148,950,356 - 148,950,554UniSTS
RH 3.4 Map51032.4UniSTS
Cytogenetic Map5q36UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
10 11 57 96 20 26 17 16 17 160 83 8 90 42 71 9 14 14

Sequence


Ensembl Acc Id: ENSRNOT00000021036   ⟹   ENSRNOP00000021036
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5155,839,929 - 155,866,541 (-)Ensembl
mRatBN7.2 Ensembl5150,556,615 - 150,583,231 (-)Ensembl
Rnor_6.0 Ensembl5156,703,579 - 156,734,541 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000075128   ⟹   ENSRNOP00000065378
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl5156,757,044 - 156,781,291 (-)Ensembl
RefSeq Acc Id: NM_001108688   ⟹   NP_001102158
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85155,839,929 - 155,866,541 (-)NCBI
mRatBN7.25150,556,615 - 150,583,231 (-)NCBI
Rnor_6.05156,703,579 - 156,734,541 (-)NCBI
Rnor_5.05160,452,101 - 160,482,729 (-)NCBI
RGSC_v3.45157,117,303 - 157,143,989 (-)RGD
Celera5148,950,060 - 148,976,672 (-)RGD
Sequence:
RefSeq Acc Id: XM_039110422   ⟹   XP_038966350
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85155,840,029 - 155,859,562 (-)NCBI
mRatBN7.25150,556,715 - 150,576,217 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001102158 (Get FASTA)   NCBI Sequence Viewer  
  XP_038966350 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL80875 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000021036
  ENSRNOP00000021036.4
RefSeq Acc Id: NP_001102158   ⟸   NM_001108688
- UniProtKB: D4AC20 (UniProtKB/TrEMBL),   A6ITH4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000021036   ⟸   ENSRNOT00000021036
RefSeq Acc Id: XP_038966350   ⟸   XM_039110422
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000065378   ⟸   ENSRNOT00000075128
Protein Domains
CMP/dCMP-type deaminase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4AC20-F1-model_v2 AlphaFold D4AC20 1-146 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311101 AgrOrtholog
BioCyc Gene G2FUF-39456 BioCyc
BioCyc Pathway PWY-7181 [pyrimidine deoxyribonucleosides degradation] BioCyc
  PWY-7193 [pyrimidine ribonucleosides salvage I] BioCyc
  PWY-7199 [pyrimidine deoxyribonucleosides salvage] BioCyc
  PWY0-1295 [pyrimidine ribonucleosides degradation] BioCyc
BioCyc Pathway Image PWY-7181 BioCyc
  PWY-7193 BioCyc
  PWY-7199 BioCyc
  PWY0-1295 BioCyc
Ensembl Genes ENSRNOG00000015677 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00000049700 Ensembl
Ensembl Transcript ENSRNOT00000021036 ENTREZGENE
  ENSRNOT00000021036.6 UniProtKB/TrEMBL
Gene3D-CATH Cytidine Deaminase, domain 2 UniProtKB/TrEMBL
InterPro APOBEC/CMP_deaminase_Zn-bd UniProtKB/TrEMBL
  CMP_dCMP_Zn-bd UniProtKB/TrEMBL
  Cyt/Deoxycyt_deaminase UniProtKB/TrEMBL
  Cyt_deam_tetra UniProtKB/TrEMBL
  Cytidine_deaminase-like UniProtKB/TrEMBL
KEGG Report rno:362638 UniProtKB/TrEMBL
NCBI Gene 362638 ENTREZGENE
PANTHER CYTIDINE DEAMINASE UniProtKB/TrEMBL
  CYTIDINE DEAMINASE UniProtKB/TrEMBL
Pfam dCMP_cyt_deam_1 UniProtKB/TrEMBL
PharmGKB CDA RGD
PhenoGen Cda PhenoGen
PROSITE CYT_DCMP_DEAMINASES UniProtKB/TrEMBL
  CYT_DCMP_DEAMINASES_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000015677 RatGTEx
  ENSRNOG00000049700 RatGTEx
Superfamily-SCOP Cytidine_deaminase-like UniProtKB/TrEMBL
UniProt A6ITH4 ENTREZGENE, UniProtKB/TrEMBL
  D4AC20 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Cda  cytidine deaminase  LOC100909857  cytidine deaminase-like  Data merged from RGD:6501229 737654 PROVISIONAL
2012-07-05 LOC100909857  cytidine deaminase-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 Cda  cytidine deaminase   Cda_predicted  cytidine deaminase (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Cda_predicted  cytidine deaminase (predicted)      Symbol and Name status set to approved 70820 APPROVED