Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Mbd6 | Rat | 17beta-estradiol | increases expression | ISO | Mbd6 (Mus musculus) | 6480464 | Estradiol results in increased expression of MBD6 mRNA | CTD | PMID:39298647 | Mbd6 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Mbd6 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to MBD6 promoter] | CTD | PMID:19654925 | Mbd6 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Mbd6 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of MBD6 mRNA | CTD | PMID:31511937 | Mbd6 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Mbd6 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of MBD6 mRNA | CTD | PMID:26290441 | Mbd6 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Mbd6 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of MBD6 mRNA | CTD | PMID:21570461 | Mbd6 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | AHR protein alternative form affects the reaction [Tetrachlorodibenzodioxin results in decreased expression of MBD6 mRNA] | CTD | PMID:21215274 | Mbd6 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of MBD6 mRNA | CTD | PMID:21215274 | Mbd6 | Rat | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2,6-dinitrotoluene affects the expression of MBD6 mRNA | CTD | PMID:21346803 | Mbd6 | Rat | 2-methylcholine | affects expression | ISO | MBD6 (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of MBD6 mRNA | CTD | PMID:21179406 | Mbd6 | Rat | 4,4'-sulfonyldiphenol | affects methylation | ISO | Mbd6 (Mus musculus) | 6480464 | bisphenol S affects the methylation of MBD6 gene | CTD | PMID:31683443 | Mbd6 | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of MBD6 mRNA | CTD | PMID:30047161 | Mbd6 | Rat | aflatoxin B1 | increases expression | ISO | Mbd6 (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of MBD6 mRNA | CTD | PMID:19770486 | Mbd6 | Rat | all-trans-retinoic acid | increases expression | ISO | MBD6 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of MBD6 mRNA | CTD | PMID:33167477 | Mbd6 | Rat | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of MBD6 mRNA | CTD | PMID:30047161 | Mbd6 | Rat | aristolochic acid A | decreases expression | ISO | MBD6 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of MBD6 mRNA | CTD | PMID:33212167 | Mbd6 | Rat | arsane | multiple interactions | ISO | MBD6 (Homo sapiens) | 6480464 | [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of MBD6 more ... | CTD | PMID:39836092 | Mbd6 | Rat | arsenic atom | multiple interactions | ISO | MBD6 (Homo sapiens) | 6480464 | [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of MBD6 more ... | CTD | PMID:39836092 | Mbd6 | Rat | arsenite(3-) | affects expression | ISO | MBD6 (Homo sapiens) | 6480464 | arsenite affects the expression of MBD6 mRNA | CTD | PMID:22959463 | Mbd6 | Rat | benzo[a]pyrene | increases expression | ISO | Mbd6 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of MBD6 mRNA | CTD | PMID:22228805 | Mbd6 | Rat | benzo[a]pyrene | increases methylation | ISO | MBD6 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of MBD6 promoter | CTD | PMID:27901495 | Mbd6 | Rat | benzo[a]pyrene | decreases methylation | ISO | MBD6 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of MBD6 3' UTR | CTD | PMID:27901495 | Mbd6 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of MBD6 mRNA | CTD | PMID:25181051 | Mbd6 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of MBD6 mRNA | CTD | PMID:30816183|PMID:33296240|PMID:34947998 | Mbd6 | Rat | bisphenol F | decreases expression | ISO | Mbd6 (Mus musculus) | 6480464 | bisphenol F results in decreased expression of MBD6 mRNA | CTD | PMID:38685157 | Mbd6 | Rat | buta-1,3-diene | decreases expression | ISO | Mbd6 (Mus musculus) | 6480464 | 1,3-butadiene results in decreased expression of MBD6 mRNA | CTD | PMID:29038090 | Mbd6 | Rat | butanal | decreases expression | ISO | MBD6 (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of MBD6 mRNA | CTD | PMID:26079696 | Mbd6 | Rat | C60 fullerene | increases expression | EXP | | 6480464 | fullerene C60 results in increased expression of MBD6 mRNA | CTD | PMID:19167457 | Mbd6 | Rat | cadmium atom | multiple interactions | ISO | MBD6 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of MBD6 more ... | CTD | PMID:35301059 | Mbd6 | Rat | cadmium atom | multiple interactions | ISO | Mbd6 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of MBD6 more ... | CTD | PMID:37325564 | Mbd6 | Rat | cadmium dichloride | multiple interactions | ISO | MBD6 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of MBD6 more ... | CTD | PMID:35301059 | Mbd6 | Rat | cadmium dichloride | multiple interactions | ISO | Mbd6 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of MBD6 more ... | CTD | PMID:37325564 | Mbd6 | Rat | caffeine | affects phosphorylation | ISO | MBD6 (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of MBD6 protein | CTD | PMID:35688186 | Mbd6 | Rat | carbon nanotube | decreases expression | ISO | Mbd6 (Mus musculus) | 6480464 | Nanotubes, Carbon analog results in decreased expression of MBD6 mRNA; Nanotubes, Carbon results in decreased more ... | CTD | PMID:25554681 | Mbd6 | Rat | chlorpyrifos | increases expression | ISO | Mbd6 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of MBD6 mRNA | CTD | PMID:37019170 | Mbd6 | Rat | DDE | decreases expression | ISO | MBD6 (Homo sapiens) | 6480464 | Dichlorodiphenyl Dichloroethylene results in decreased expression of MBD6 mRNA | CTD | PMID:38568856 | Mbd6 | Rat | Dibutyl phosphate | affects expression | ISO | MBD6 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of MBD6 mRNA | CTD | PMID:37042841 | Mbd6 | Rat | dicrotophos | increases expression | ISO | MBD6 (Homo sapiens) | 6480464 | dicrotophos results in increased expression of MBD6 mRNA | CTD | PMID:28302478 | Mbd6 | Rat | disodium selenite | increases expression | ISO | MBD6 (Homo sapiens) | 6480464 | Sodium Selenite results in increased expression of MBD6 mRNA | CTD | PMID:18175754 | Mbd6 | Rat | doxorubicin | decreases expression | ISO | MBD6 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of MBD6 mRNA | CTD | PMID:29803840 | Mbd6 | Rat | ethyl methanesulfonate | increases expression | ISO | MBD6 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in increased expression of MBD6 mRNA | CTD | PMID:23649840 | Mbd6 | Rat | formaldehyde | increases expression | ISO | MBD6 (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of MBD6 mRNA | CTD | PMID:23649840 | Mbd6 | Rat | FR900359 | increases phosphorylation | ISO | MBD6 (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of MBD6 protein | CTD | PMID:37730182 | Mbd6 | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of MBD6 mRNA | CTD | PMID:33387578 | Mbd6 | Rat | hydralazine | multiple interactions | ISO | MBD6 (Homo sapiens) | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of MBD6 mRNA | CTD | PMID:17183730 | Mbd6 | Rat | manganese atom | multiple interactions | ISO | MBD6 (Homo sapiens) | 6480464 | [manganese chloride results in increased abundance of Manganese] which results in increased expression of MBD6 more ... | CTD | PMID:39836092 | Mbd6 | Rat | manganese(0) | multiple interactions | ISO | MBD6 (Homo sapiens) | 6480464 | [manganese chloride results in increased abundance of Manganese] which results in increased expression of MBD6 more ... | CTD | PMID:39836092 | Mbd6 | Rat | manganese(II) chloride | multiple interactions | ISO | MBD6 (Homo sapiens) | 6480464 | [manganese chloride results in increased abundance of Manganese] which results in increased expression of MBD6 more ... | CTD | PMID:39836092 | Mbd6 | Rat | methimazole | decreases expression | EXP | | 6480464 | Methimazole results in decreased expression of MBD6 mRNA | CTD | PMID:30047161 | Mbd6 | Rat | methyl methanesulfonate | increases expression | ISO | MBD6 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of MBD6 mRNA | CTD | PMID:23649840 | Mbd6 | Rat | ozone | multiple interactions | ISO | MBD6 (Homo sapiens) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which affects the expression of MBD6 mRNA | CTD | PMID:35430440 | Mbd6 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of MBD6 mRNA | CTD | PMID:33387578 | Mbd6 | Rat | perfluorononanoic acid | decreases expression | ISO | MBD6 (Homo sapiens) | 6480464 | perfluoro-n-nonanoic acid results in decreased expression of MBD6 mRNA | CTD | PMID:38568856 | Mbd6 | Rat | pirinixic acid | increases expression | ISO | Mbd6 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of MBD6 mRNA | CTD | PMID:18301758 | Mbd6 | Rat | quercetin | increases expression | ISO | MBD6 (Homo sapiens) | 6480464 | Quercetin results in increased expression of MBD6 mRNA | CTD | PMID:21632981 | Mbd6 | Rat | resveratrol | multiple interactions | ISO | MBD6 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of MBD6 mRNA | CTD | PMID:23557933 | Mbd6 | Rat | sodium arsenite | increases expression | ISO | MBD6 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of MBD6 mRNA | CTD | PMID:38568856 | Mbd6 | Rat | sodium arsenite | multiple interactions | ISO | MBD6 (Homo sapiens) | 6480464 | [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of MBD6 more ... | CTD | PMID:39836092 | Mbd6 | Rat | sulfadimethoxine | decreases expression | EXP | | 6480464 | Sulfadimethoxine results in decreased expression of MBD6 mRNA | CTD | PMID:30047161 | Mbd6 | Rat | sunitinib | increases expression | ISO | MBD6 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of MBD6 mRNA | CTD | PMID:31533062 | Mbd6 | Rat | thapsigargin | increases expression | ISO | MBD6 (Homo sapiens) | 6480464 | Thapsigargin results in increased expression of MBD6 mRNA | CTD | PMID:22378314 | Mbd6 | Rat | thiram | increases expression | ISO | MBD6 (Homo sapiens) | 6480464 | Thiram results in increased expression of MBD6 mRNA | CTD | PMID:38568856 | Mbd6 | Rat | titanium dioxide | decreases methylation | ISO | Mbd6 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of MBD6 gene | CTD | PMID:35295148 | Mbd6 | Rat | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of MBD6 mRNA | CTD | PMID:33387578 | Mbd6 | Rat | triphenyl phosphate | affects expression | ISO | MBD6 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of MBD6 mRNA | CTD | PMID:37042841 | Mbd6 | Rat | tungsten | decreases expression | ISO | Mbd6 (Mus musculus) | 6480464 | Tungsten results in decreased expression of MBD6 mRNA | CTD | PMID:30912803 | Mbd6 | Rat | urethane | increases expression | ISO | MBD6 (Homo sapiens) | 6480464 | Urethane results in increased expression of MBD6 mRNA | CTD | PMID:28818685 | Mbd6 | Rat | valproic acid | multiple interactions | ISO | MBD6 (Homo sapiens) | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of MBD6 mRNA | CTD | PMID:17183730 | Mbd6 | Rat | valproic acid | affects expression | ISO | MBD6 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of MBD6 mRNA | CTD | PMID:25979313 | Mbd6 | Rat | valproic acid | affects expression | ISO | Mbd6 (Mus musculus) | 6480464 | Valproic Acid affects the expression of MBD6 mRNA | CTD | PMID:17292431 | Mbd6 | Rat | valproic acid | increases expression | ISO | Mbd6 (Mus musculus) | 6480464 | Valproic Acid results in increased expression of MBD6 mRNA | CTD | PMID:21427059 | Mbd6 | Rat | valproic acid | decreases expression | ISO | Mbd6 (Mus musculus) | 6480464 | Valproic Acid results in decreased expression of MBD6 mRNA | CTD | PMID:21427059 | Mbd6 | Rat | zinc atom | multiple interactions | ISO | MBD6 (Homo sapiens) | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of MBD6 mRNA | CTD | PMID:18593933 | Mbd6 | Rat | zinc(0) | multiple interactions | ISO | MBD6 (Homo sapiens) | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of MBD6 mRNA | CTD | PMID:18593933 | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















