Imported Disease Annotations - OMIMObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Hscb | Rat | Sideroblastic Anemia 5 | | ISO | HSCB (Homo sapiens) | 7240710 | | OMIM | | |
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Imported Disease Annotations - OMIMObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Hscb | Rat | Sideroblastic Anemia 5 | | ISO | HSCB (Homo sapiens) | 7240710 | | OMIM | | |
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# | Reference Title | Reference Citation |
1. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
2. | Iron-sulfur cluster biogenesis in mammalian cells: New insights into the molecular mechanisms of cluster delivery. | Maio N and Rouault TA, Biochim Biophys Acta. 2015 Jun;1853(6):1493-512. doi: 10.1016/j.bbamcr.2014.09.009. Epub 2014 Sep 19. |
3. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
Hscb (Rattus norvegicus - Norway rat) |
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HSCB (Homo sapiens - human) |
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Hscb (Mus musculus - house mouse) |
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Hscb (Chinchilla lanigera - long-tailed chinchilla) |
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HSCB (Pan paniscus - bonobo/pygmy chimpanzee) |
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HSCB (Canis lupus familiaris - dog) |
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Hscb (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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HSCB (Sus scrofa - pig) |
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HSCB (Chlorocebus sabaeus - green monkey) |
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Hscb (Heterocephalus glaber - naked mole-rat) |
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Variants in Hscb
57 total Variants |
The detailed report is available here: | Full Report | CSV | TAB | Printer | ||||
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
The following QTLs overlap with this region. | Full Report | CSV | TAB | Printer | Gviewer |
RH134477 |
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alimentary part of gastrointestinal system
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appendage
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circulatory system
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ectoderm
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endocrine system
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endoderm
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exocrine system
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hemolymphoid system
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hepatobiliary system
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integumental system
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mesenchyme
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mesoderm
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nervous system
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renal system
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reproductive system
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respiratory system
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9 | 11 | 49 | 113 | 91 | 90 | 59 | 25 | 59 | 6 | 218 | 97 | 93 | 45 | 60 | 31 |
Ensembl Acc Id: | ENSRNOT00000056798 ⟹ ENSRNOP00000053641 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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Ensembl Acc Id: | ENSRNOT00000096303 ⟹ ENSRNOP00000083969 | ||||||||
Type: | CODING | ||||||||
Position: |
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Ensembl Acc Id: | ENSRNOT00000102335 ⟹ ENSRNOP00000085570 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | NM_001108340 ⟹ NP_001101810 | ||||||||||||||||||||||||||||
RefSeq Status: | PROVISIONAL | ||||||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_006249564 ⟹ XP_006249626 | ||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_008769340 ⟹ XP_008767562 | ||||||||||||||||
Type: | CODING | ||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_039089616 ⟹ XP_038945544 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | XM_039089617 ⟹ XP_038945545 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | XM_039089618 ⟹ XP_038945546 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | XM_063271547 ⟹ XP_063127617 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | NP_001101810 ⟸ NM_001108340 |
- Peptide Label: | precursor |
- UniProtKB: | D3ZME7 (UniProtKB/TrEMBL), A6J288 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_006249626 ⟸ XM_006249564 |
- Peptide Label: | isoform X2 |
- UniProtKB: | A0A8I5ZYF5 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_008767562 ⟸ XM_008769340 |
- Peptide Label: | isoform X1 |
- UniProtKB: | A0A8I6A2K9 (UniProtKB/TrEMBL) |
- Sequence: |
Ensembl Acc Id: | ENSRNOP00000053641 ⟸ ENSRNOT00000056798 |
RefSeq Acc Id: | XP_038945544 ⟸ XM_039089616 |
- Peptide Label: | isoform X3 |
RefSeq Acc Id: | XP_038945546 ⟸ XM_039089618 |
- Peptide Label: | isoform X6 |
RefSeq Acc Id: | XP_038945545 ⟸ XM_039089617 |
- Peptide Label: | isoform X4 |
- UniProtKB: | A6J289 (UniProtKB/TrEMBL) |
Ensembl Acc Id: | ENSRNOP00000085570 ⟸ ENSRNOT00000102335 |
Ensembl Acc Id: | ENSRNOP00000083969 ⟸ ENSRNOT00000096303 |
RefSeq Acc Id: | XP_063127617 ⟸ XM_063271547 |
- Peptide Label: | isoform X5 |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-D3ZME7-F1-model_v2 | AlphaFold | D3ZME7 | 1-234 | view protein structure |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
RGD ID: | 13698733 | ||||||||
Promoter ID: | EPDNEW_R9257 | ||||||||
Type: | initiation region | ||||||||
Name: | Hscb_1 | ||||||||
Description: | HscB mitochondrial iron-sulfur cluster co-chaperone | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
Experiment Methods: | Single-end sequencing. | ||||||||
Position: |
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Database | Acc Id | Source(s) |
AGR Gene | RGD:1311005 | AgrOrtholog |
BioCyc Gene | G2FUF-18827 | BioCyc |
Ensembl Genes | ENSRNOG00000037508 | Ensembl, UniProtKB/TrEMBL |
Ensembl Transcript | ENSRNOT00000056798.4 | UniProtKB/TrEMBL |
ENSRNOT00000096303.1 | UniProtKB/TrEMBL | |
ENSRNOT00000102335.1 | UniProtKB/TrEMBL | |
Gene3D-CATH | 1.10.287.110 | UniProtKB/TrEMBL |
1.20.1280.20 | UniProtKB/TrEMBL | |
InterPro | DnaJ_dom_sf | UniProtKB/TrEMBL |
DnaJ_N | UniProtKB/TrEMBL | |
Heat_shock_cognate_B_oligo_C | UniProtKB/TrEMBL | |
HscB | UniProtKB/TrEMBL | |
HscB_4_cys | UniProtKB/TrEMBL | |
HscB_C_sf | UniProtKB/TrEMBL | |
KEGG Report | rno:360826 | UniProtKB/TrEMBL |
NCBI Gene | 360826 | ENTREZGENE |
PANTHER | IRON-SULFUR CLUSTER CO-CHAPERONE PROTEIN HSCB | UniProtKB/TrEMBL |
PTHR14021 | UniProtKB/TrEMBL | |
Pfam | HscB_4_cys | UniProtKB/TrEMBL |
HSCB_C | UniProtKB/TrEMBL | |
PhenoGen | Hscb | PhenoGen |
PROSITE | DNAJ_2 | UniProtKB/TrEMBL |
RatGTEx | ENSRNOG00000037508 | RatGTEx |
SMART | DnaJ | UniProtKB/TrEMBL |
Superfamily-SCOP | DnaJ_N | UniProtKB/TrEMBL |
HSC20_C | UniProtKB/TrEMBL | |
UniProt | A0A8I5ZYF5 | ENTREZGENE, UniProtKB/TrEMBL |
A0A8I6A2K9 | ENTREZGENE, UniProtKB/TrEMBL | |
A6J288 | ENTREZGENE, UniProtKB/TrEMBL | |
A6J289 | ENTREZGENE, UniProtKB/TrEMBL | |
D3ZME7 | ENTREZGENE, UniProtKB/TrEMBL |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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2013-09-18 | Hscb | HscB mitochondrial iron-sulfur cluster co-chaperone | Hscb | HscB iron-sulfur cluster co-chaperone homolog (E. coli) | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2008-02-27 | Hscb | HscB iron-sulfur cluster co-chaperone homolog (E. coli) | RGD1311005_predicted | similar to J-type co-chaperone HSC20 (predicted) | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2005-01-20 | RGD1311005_predicted | similar to J-type co-chaperone HSC20 (predicted) | LOC360826_predicted | Symbol and Name status set to approved | 1331353 | APPROVED | |
2005-01-12 | LOC360826_predicted | similar to J-type co-chaperone HSC20 (predicted) | Symbol and Name status set to provisional | 70820 | PROVISIONAL |