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Gene: Cwh43 (cell wall biogenesis 43 C-terminal homolog) Rattus norvegicus

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Symbol:

Cwh43

Name:

cell wall biogenesis 43 C-terminal homolog

RGD ID:

1310958

Description:

Predicted to be involved in GPI anchor biosynthetic process. Predicted to act upstream of or within several processes, including cerebrospinal fluid circulation; protein glycosylation; and protein import into nucleus. Predicted to be located in extracellular region and membrane. Predicted to be active in endoplasmic reticulum. Orthologous to human CWH43 (cell wall biogenesis 43 C-terminal homolog); INTERACTS WITH 6-propyl-2-thiouracil; alpha-Zearalanol; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

cell wall biogenesis 43 C-terminal homolog (S. cerevisiae); LOC305307; PGAP2-interacting protein; RGD1310958; similar to RIKEN cDNA C130090K23

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	35,108,328 - 35,154,578 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	14	35,108,338 - 35,154,863 (-)	Ensembl				GRCr8
mRatBN7.2	14	34,754,279 - 34,800,530 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	34,754,289 - 34,800,814 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	14	35,114,822 - 35,161,040 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	36,422,457 - 36,468,679 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	34,907,905 - 34,954,123 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	37,315,479 - 37,361,728 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	37,315,406 - 37,361,798 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	14	37,134,049 - 37,180,552 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	14	37,160,286 - 37,206,533 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	14	34,016,170 - 34,062,259 (-)	NCBI		Celera
RGSC_v3.1	14	37,163,065 - 37,211,146 (-)	NCBI
Cytogenetic Map	14	p11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Lung Neoplasms (ISO)

normal pressure hydrocephalus (ISS)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

2-hydroxypropanoic acid (ISO)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP,ISO)

alpha-Zearalanol (EXP)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP)

Butylbenzyl phthalate (ISO)

cadmium dichloride (ISO)

chlordecone (ISO)

chromium(6+) (ISO)

diiodine (ISO)

fulvestrant (ISO)

furan (EXP)

ozone (ISO)

perfluorooctanoic acid (EXP)

progesterone (ISO)

rac-lactic acid (ISO)

sodium arsenate (ISO)

sodium fluoride (ISO)

titanium dioxide (ISO)

trichloroethene (EXP)

valproic acid (ISO)

vinclozolin (EXP)

vitamin E (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

brain development (ISO)

cell adhesion (ISO)

cerebrospinal fluid circulation (ISO)

cilium organization (ISO)

gene expression (ISO)

glycoprotein biosynthetic process (ISO)

GPI anchor biosynthetic process (IBA,IEA)

intracellular protein localization (ISO)

membrane protein ectodomain proteolysis (ISO)

membrane protein proteolysis (ISO)

neuromuscular process controlling balance (ISO)

peptide secretion (ISO)

protein import into nucleus (ISO)

protein localization to extracellular region (ISO)

protein N-linked glycosylation (ISO)

protein targeting to membrane (ISO)

proteolysis (ISO)

regulation of intracellular signal transduction (ISO)

regulation of protein import into nucleus (ISO)

regulation of protein localization (ISO)

regulation of protein localization to nucleus (ISO)

regulation of protein processing (ISO)

walking behavior (ISO)

Cellular Component

endoplasmic reticulum (IBA)

extracellular region (IEA)

membrane (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data

Cwh43
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	35,108,328 - 35,154,578 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	14	35,108,338 - 35,154,863 (-)	Ensembl				GRCr8
mRatBN7.2	14	34,754,279 - 34,800,530 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	34,754,289 - 34,800,814 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	14	35,114,822 - 35,161,040 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	36,422,457 - 36,468,679 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	34,907,905 - 34,954,123 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	37,315,479 - 37,361,728 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	37,315,406 - 37,361,798 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	14	37,134,049 - 37,180,552 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	14	37,160,286 - 37,206,533 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	14	34,016,170 - 34,062,259 (-)	NCBI		Celera
RGSC_v3.1	14	37,163,065 - 37,211,146 (-)	NCBI
Cytogenetic Map	14	p11	NCBI

CWH43
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	4	48,986,275 - 49,062,079 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	4	48,986,162 - 49,062,093 (+)	Ensembl			hg38	GRCh38
GRCh37	4	48,988,292 - 49,064,096 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	4	48,683,022 - 48,758,853 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	4	49,436,682 - 49,512,564 (+)	NCBI		Celera
Cytogenetic Map	4	p11	NCBI
HuRef	4	48,308,092 - 48,383,970 (+)	NCBI		HuRef
CHM1_1	4	48,987,373 - 49,063,204 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	4	48,952,880 - 49,028,711 (+)	NCBI		T2T-CHM13v2.0

Cwh43
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	73,563,394 - 73,610,778 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	73,563,418 - 73,610,778 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	5	73,406,051 - 73,453,435 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	73,406,075 - 73,453,435 (+)	Ensembl			mm10	GRCm38
MGSCv37	5	73,797,317 - 73,844,664 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	5	73,685,213 - 73,732,560 (+)	NCBI		MGSCv36	mm8
Celera	5	70,661,918 - 70,710,783 (+)	NCBI		Celera
Cytogenetic Map	5	C3.3	NCBI
cM Map	5	38.78	NCBI

Cwh43
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955447	18,680,779 - 18,734,428 (-)	Ensembl
ChiLan1.0	NW_004955447	18,683,173 - 18,733,546 (-)	NCBI	ChiLan1.0	ChiLan1.0

CWH43
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	3	78,813,896 - 78,878,889 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	4	79,063,990 - 79,140,250 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	4	73,092,093 - 73,168,001 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	4	83,820,735 - 83,896,192 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	4	83,820,733 - 83,896,296 (-)	Ensembl			panPan2	panpan1.1

CWH43
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	13	44,724,127 - 44,782,788 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	13	44,724,131 - 44,782,804 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	13	44,674,846 - 44,735,553 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	13	45,324,215 - 45,384,991 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	13	45,324,143 - 45,384,976 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	13	44,999,786 - 45,060,255 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	13	44,533,959 - 44,594,966 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	13	45,414,686 - 45,475,361 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Cwh43
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405285	31,346,105 - 31,396,772 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936482	14,902,011 - 14,952,123 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936482	14,902,011 - 14,952,123 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CWH43
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	8	38,869,138 - 38,943,669 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	8	38,869,156 - 38,944,845 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	8	41,045,903 - 41,121,517 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CWH43
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	27	1,199,363 - 1,281,422 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	27	1,199,370 - 1,281,308 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666047	47,160,950 - 47,260,044 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cwh43
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624761	17,945,350 - 18,014,246 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624761	17,908,703 - 18,014,539 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Cwh43
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	11	30,208,117 - 30,252,754 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Cwh43
344 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	59
Count of miRNA genes:	52
Interacting mature miRNAs:	58
Transcripts:	ENSRNOT00000002980
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631528	Scl11	Serum cholesterol level QTL 11	4.9		blood cholesterol amount (VT:0000180)	blood total cholesterol level (CMO:0000051)	14	17875645	36079022	Rat
7411573	Bw139	Body weight QTL 139	4.7	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	14	1	40068101	Rat
9589814	Gluco67	Glucose level QTL 67	4.54	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	14	1	40068101	Rat
731183	Pia20	Pristane induced arthritis QTL 20	3.55		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	14	9393298	39411170	Rat
1300154	Bp189	Blood pressure QTL 189	3.04		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	14	31238080	72970315	Rat
70187	Pancm5	Pancreatic morphology QTL 5	16.7		pancreas mass (VT:0010144)	pancreas weight to body weight ratio (CMO:0000630)	14	30674469	85041098	Rat
2324617	Coatc2	Coat color QTL 2		0.001	coat/hair pigmentation trait (VT:0010463)	pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)	14	31121333	39507682	Rat
631523	Pia13	Pristane induced arthritis QTL 13	3.3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	14	33424686	102238540	Rat
1358296	Ael3	Aortic elastin QTL 3	3.7	0.00051	aorta elastin amount (VT:0003905)	aortic elastin	14	8621398	53621398	Rat
61420	Pia6	Pristane induced arthritis QTL 6	4.9		joint integrity trait (VT:0010548)	arthritic paw count (CMO:0001460)	14	18915454	42433608	Rat
7387267	Uae42	Urinary albumin excretion QTL 42		0.61	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	14	22521517	67521517	Rat
631839	Niddm37	Non-insulin dependent diabetes mellitus QTL 37	3.37		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	14	11334716	100078267	Rat
2313397	Coatc1	Coat color QTL1			coat/hair pigmentation trait (VT:0010463)	coat/hair color measurement (CMO:0001808)	14	18895192	63895192	Rat
631262	Tcas4	Tongue tumor susceptibility QTL 4	7.29		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	14	17906726	54251504	Rat
634352	Apr6	Acute phase response QTL 6	3.7		blood interleukin-6 amount (VT:0008595)	plasma interleukin-6 level (CMO:0001927)	14	1	41415516	Rat
2302045	Pia39	Pristane induced arthritis QTL 39	4.9	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G2a level (CMO:0002116)	14	8621398	53621398	Rat

Markers in Region

RH140184

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	14	34,754,288 - 34,754,504 (+)	MAPPER	mRatBN7.2
Rnor_6.0	14	37,315,489 - 37,315,704	NCBI	Rnor6.0
Rnor_5.0	14	37,134,059 - 37,134,274	UniSTS	Rnor5.0
RGSC_v3.4	14	37,160,296 - 37,160,511	UniSTS	RGSC3.4
Celera	14	34,016,180 - 34,016,395	UniSTS
Cytogenetic Map	14	p11	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	4	4	103	21	33	4	45	4	6	153	55	3	94	75	78	29	9	9

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001191677	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473981	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000014	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000002980 ⟹ ENSRNOP00000002980

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	14	35,108,338 - 35,154,863 (-)	Ensembl
mRatBN7.2 Ensembl	14	34,754,289 - 34,800,814 (-)	Ensembl
Rnor_6.0 Ensembl	14	37,315,406 - 37,361,798 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000102154 ⟹ ENSRNOP00000082169

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	14	35,108,338 - 35,154,863 (-)	Ensembl
mRatBN7.2 Ensembl	14	34,754,289 - 34,800,814 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000118435 ⟹ ENSRNOP00000081875

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	14	34,754,289 - 34,800,814 (-)	Ensembl

RefSeq Acc Id:

NM_001191677 ⟹ NP_001178606

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	35,108,328 - 35,154,578 (-)	NCBI
mRatBN7.2	14	34,754,279 - 34,800,530 (-)	NCBI
Rnor_6.0	14	37,315,479 - 37,361,728 (-)	NCBI
Rnor_5.0	14	37,134,049 - 37,180,552 (-)	NCBI
Celera	14	34,016,170 - 34,062,259 (-)	NCBI

Sequence:

show sequence

ATGCCAAGCCTGTGGAGAGCAATTGCCCTGGAGACCTTGCTGGGCTACATCTCCTGGTCTCTCT
ACCACGGACTGGGCCCCATGATCTATTACTTTCCCCTGCAGACACTGGAGCTCACAGGGCTGGA
AGTGTTTGGCGTAGCCTTTCTCTCTCCGATACTCCTTACAATCCCCCCATTCTGGAAACTCGTC
AAGAAAAAGCGGGCACTCACTTTGCTGAGGATCATTACTGTAGGCAGCGTAGCCTCCTTTGAGG
CTCCGAATGCCAAACTTCGACTGATAGTCCTTGCCCTTGGTGTGTCTTCTTCCCTGATCGTGCA
GACTGTGACCTGGTGGTCAGGAAGTGGACTGCAAAGGTACCTCAAAATCTGGGGATTCATTCTG
GGACACATTCTTCTTCTTGTCCTCCGAATATGGTACACATCGTTAAACCCAATTTGGAGCTATC
AGATGTCCAACAGAGTCATTCTGTCACTGAGTGCCATAGCTGTGTTCGACCGAATTAGCACAGA
TGGTGACTACAGAAACCCTGAGGGGAAGAAACCGGATGAGGCCGCCACGCGCAGGACCTCTCTA
TCCAGTTGGCTGTTGCCAGGTGCCGCCTTCGGGAGCCTCGTGTTCCTCACGCACTGGATCTTTG
GAGAGGTCTCCATTGTTTCCAGATGGGCAGTGAGCGGTCATCCCCACCCAGGGCCTGATCCGAA
TCCTTTTGGAGGTGCGGTTCTGCTGGGCTTCGCAAGTGGACTGATGCTATCGGGCTCATCATGG
CTTTGTGACACTGGGTTAGCCTGGTGGATGACAGGAGCAACTTCAGCCATGGGTCTCCTTTATC
TGCGCACTTGGGCAGCCGCTGTTTCTGGATGCGCACTGGCAGTCTTCACAGGGTCCATGTGGCC
TCAAGTACTTGGACATCTTATGAACTCAGGGACAAACCCTGGAGGAGCCATGACCACTGGCATG
AGCCTTTATGTTCTACAAGTGTTTTTCTGTGCCTGGTGCACAGCTTTTAAGTTTGTTCCTGGAG
GTGTCTACGCTAGAGAAAGGTCTGATGTGCTTTTGGGGATCATAATGGTAATTATTGGATTGAG
CATGCTGTTTAGACCTAAGAAAAACCTTGACTTTCTTCTTCAAACAAAAAACAGCTCTAAAATG
CTTTTAAGAAGCACTGAAAAATACATGAAACTTATTTTGTGGCTGCTTGTTGGTGTGGGGTTAC
TGGGATTAGGACTGCGGCACAGAACCTATGAGAGAAAATTAGGCCACGGGGCACCAGCGGACGT
GGTCTCGGCTGCCATCTGGCCTTTTAGGTTTGGATACGACAATGAAGGATGGTCCAATCTAGAG
CGGTCTGCTCAGCTGCTCAAGCAGACGGGTGCAGATTTTATTACCATTTTGGAGAGTGACGCTT
CTAAGCCCTATATGGGGAACAATGACTTAACCATGTGGCTGGGGGAGAAGTTGGGTTTCTATAC
AGACTTTGGGCCAAGCACCAGGGATCACACATGGGGGATTATGGTTCTGTCTCGGTACCCGATT
GTGAGATCGGAACATCACCTTCTTCCGTCACCAGAGGGCGAGATCGCACCAGCCATAACCATGA
CAGTTAACATCTCCGACAGACTGGTGGATTTTGTGGTGACACACTTCGGGAATCATGAAGATGA
CCTTGACAGGAAGCTACAGGCTATTGCAGTTTCAAAACTGCTGAAAAATTGTTCAAATCAAGTG
ATATTTTTGGGCTACATCACTTCAGAGCCTGGTTCCAGAGACTACACACAACTCACAAAACATG
GCCATGTGAAGGATATTGACAGCTCAGATCGAGACAGATGGTGTGAATATATCATGTATCGGGG
CCTGATCAGGTTGGGTTATGCAAGGATTTCTCATGCTGAACTGAGTGACTCTGAGATTCAGATG
GCCAAATTCAGGATTCCAGATGATCCCTTCAATTACAGAGACAACCAGAGAGTCGTCATAGACC
ACAGAGGAGTTCCCAAGAACATTCATTTCAACCCGAGATTTGGCTCCTACAAAGAAGGACACAA
TCACGAGAACAACCATCATTTTCACATGAATACACCCAAGTACTTCGTGTGAACCATTTTAGAC
AAGAAGTCATCATCGAATGGAGAAATATGTAACAGCCCAAATTAGAGTTTAATGAAAATGGGAG
AATACACGTGAAGAATCTCAGGAGTTAAAAAAAAAAGAAACAAAAGAAAAAGAAAAAGATGACA
TCATGCAATGAGACTCCCATAAATTGTAAGCTATGCTGCTTAATAAAGGCATCCCTCTGATGTA
CTTTTGTTTAGAAACAGAAGTGCGATTCTATAAGAAAGCTGAGCTCAGGCCTGGAGCTGGAGCT
TGGTGGTAAAGGGGTTGCCTCGTGTGCGTGGGGCCCTAGTTTCAGTTCCCAGCACTGCCAGAAA
TAAAGCGGAGAGGACACAGGAAAAAAGAAA

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Protein Sequences


Protein RefSeqs	NP_001178606	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL89954	(Get FASTA)	NCBI Sequence Viewer
	EDL89955	(Get FASTA)	NCBI Sequence Viewer
	EDL89956	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000002980
	ENSRNOP00000002980.4
	ENSRNOP00000082169.1

RefSeq Acc Id:

NP_001178606 ⟸ NM_001191677

- UniProtKB:

D4A4R9 (UniProtKB/TrEMBL), A6JD33 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MPSLWRAIALETLLGYISWSLYHGLGPMIYYFPLQTLELTGLEVFGVAFLSPILLTIPPFWKLV
KKKRALTLLRIITVGSVASFEAPNAKLRLIVLALGVSSSLIVQTVTWWSGSGLQRYLKIWGFIL
GHILLLVLRIWYTSLNPIWSYQMSNRVILSLSAIAVFDRISTDGDYRNPEGKKPDEAATRRTSL
SSWLLPGAAFGSLVFLTHWIFGEVSIVSRWAVSGHPHPGPDPNPFGGAVLLGFASGLMLSGSSW
LCDTGLAWWMTGATSAMGLLYLRTWAAAVSGCALAVFTGSMWPQVLGHLMNSGTNPGGAMTTGM
SLYVLQVFFCAWCTAFKFVPGGVYARERSDVLLGIIMVIIGLSMLFRPKKNLDFLLQTKNSSKM
LLRSTEKYMKLILWLLVGVGLLGLGLRHRTYERKLGHGAPADVVSAAIWPFRFGYDNEGWSNLE
RSAQLLKQTGADFITILESDASKPYMGNNDLTMWLGEKLGFYTDFGPSTRDHTWGIMVLSRYPI
VRSEHHLLPSPEGEIAPAITMTVNISDRLVDFVVTHFGNHEDDLDRKLQAIAVSKLLKNCSNQV
IFLGYITSEPGSRDYTQLTKHGHVKDIDSSDRDRWCEYIMYRGLIRLGYARISHAELSDSEIQM
AKFRIPDDPFNYRDNQRVVIDHRGVPKNIHFNPRFGSYKEGHNHENNHHFHMNTPKYFV

hide sequence

Ensembl Acc Id:

ENSRNOP00000002980 ⟸ ENSRNOT00000002980

Ensembl Acc Id:

ENSRNOP00000082169 ⟸ ENSRNOT00000102154

Ensembl Acc Id:

ENSRNOP00000081875 ⟸ ENSRNOT00000118435

Protein Domains

PGAP2IP C-terminal nuclease-like PGAP2IP first transmembrane PGAP2IP second transmembrane

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D4A4R9-F1-model_v2	AlphaFold	D4A4R9	1-699	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13699293

Promoter ID:

EPDNEW_R9818

Type:

multiple initiation site

Name:

Cwh43_1

Description:

cell wall biogenesis 43 C-terminal homolog

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	14	37,361,837 - 37,361,897	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1310958	AgrOrtholog
BioCyc Gene	G2FUF-15868	BioCyc
Ensembl Genes	ENSRNOG00000002174	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000002980	ENTREZGENE
	ENSRNOT00000002980.9	UniProtKB/TrEMBL
	ENSRNOT00000102154.2	UniProtKB/TrEMBL
Gene3D-CATH	3.60.10.10	UniProtKB/TrEMBL
InterPro	Endo/exonu/phosph_ase_sf	UniProtKB/TrEMBL
	Exo_endo_phos_PGAP2IP_C	UniProtKB/TrEMBL
	GPI-anchor_lipid_remodeler	UniProtKB/TrEMBL
	PGAP2IP_TM_1nd	UniProtKB/TrEMBL
	PGAP2IP_TM_2nd	UniProtKB/TrEMBL
KEGG Report	rno:305307	UniProtKB/TrEMBL
NCBI Gene	305307	ENTREZGENE
PANTHER	CALCOFLUOR WHITE HYPERSENSITIVE PROTEIN PRECURSOR	UniProtKB/TrEMBL
	PTHR14859:SF1	UniProtKB/TrEMBL
Pfam	Exo_endo_phos_PGAP2IP	UniProtKB/TrEMBL
	PGAP2IP_TM_1nd	UniProtKB/TrEMBL
	PGAP2IP_TM_2nd	UniProtKB/TrEMBL
PhenoGen	Cwh43	PhenoGen
RatGTEx	ENSRNOG00000002174	RatGTEx
Superfamily-SCOP	Exo_endo_phos	UniProtKB/TrEMBL
UniProt	A0A8I5ZTZ5_RAT	UniProtKB/TrEMBL
	A6JD33	ENTREZGENE, UniProtKB/TrEMBL
	D4A4R9	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-07-09	Cwh43	cell wall biogenesis 43 C-terminal homolog	Cwh43	cell wall biogenesis 43 C-terminal homolog (S. cerevisiae)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2010-04-23	Cwh43	cell wall biogenesis 43 C-terminal homolog (S. cerevisiae)	RGD1310958	similar to RIKEN cDNA C130090K23	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	RGD1310958	similar to RIKEN cDNA C130090K23	RGD1310958_predicted	similar to RIKEN cDNA C130090K23 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-20	RGD1310958_predicted	similar to RIKEN cDNA C130090K23 (predicted)	LOC305307_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC305307_predicted	similar to RIKEN cDNA C130090K23 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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