Spsb2 (splA/ryanodine receptor domain and SOCS box containing 2) - Rat Genome Database

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Gene: Spsb2 (splA/ryanodine receptor domain and SOCS box containing 2) Rattus norvegicus
Analyze
Symbol: Spsb2
Name: splA/ryanodine receptor domain and SOCS box containing 2
RGD ID: 1310854
Description: Predicted to enable ubiquitin ligase-substrate adaptor activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process and protein ubiquitination. Predicted to be located in cytosol. Predicted to be part of SCF ubiquitin ligase complex. Orthologous to human SPSB2 (splA/ryanodine receptor domain and SOCS box containing 2); INTERACTS WITH 2,6-dinitrotoluene; all-trans-retinoic acid; amphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: gene rich cluster, C9 gene; Grcc9; LOC100911548; LOC297592; MGC108858; SPRY domain-containing SOCS box protein 2; SPRY domain-containing SOCS box protein 2-like; SPRY domain-containing SOCS box protein SSB-2; SSB-2
RGD Orthologs
Human
Mouse
Dog
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
NCBI Annotation Information: Note: LOC100911548 (GeneID: 100911548) appears to be a duplicate placement of Spsb2 (GeneID: 297592) on Rnor_6.0 (Annot. Release 105) that is absent from Rn_Celera and is not supported by syntenic regions in mouse and human. BLAST analysis of the underlying component AABR07066868.1 against the rat genome shows 88% coverage and 99% identity with NC_005103.4, at the location where Spsb2 is annotated. Annotation of Spsb2 (GeneID: 297592) at this location on Rnor_6.0 is supported by annotation on Rn_Celera and synteny with mouse and human. This apparent duplication could be explained by misassembly of several underlying components on Rnor_6.0. LOC100911548 is bracketed by two genes, Gpr116 and Gpr110, which serve as a useful frame of reference, on the rat reference assembly. The region between these two genes also includes several other genes with names beginning with "LOC". However, on the Celera assembly as well as at the syntenic region in the mouse genome, these "LOC" genes are not annotated between Gpr116 and Gpr110. This suggests that the underlying components for these "LOC" genes could be misassembled in Rnor_6.0, including AABR07066868.1, AABR07066869.1, and AABR07066870.1. [14 Apr 2021]
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84159,298,362 - 159,301,568 (+)NCBIGRCr8
mRatBN7.24157,613,404 - 157,615,293 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4157,613,401 - 157,615,284 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4163,841,571 - 163,843,460 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04159,624,481 - 159,626,370 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04158,260,087 - 158,261,976 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04157,325,980 - 157,328,380 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4157,326,727 - 157,328,379 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl920,217,278 - 20,219,209 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04224,343,582 - 224,346,314 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44160,931,693 - 160,933,346 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14161,176,628 - 161,178,281 (+)NCBI
Celera4146,351,625 - 146,353,278 (+)NCBICelera
Cytogenetic Map4q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IEA,ISO,ISS)
SCF ubiquitin ligase complex  (IBA,IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:15489334   PMID:20603330   PMID:21199876  


Genomics

Comparative Map Data
Spsb2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84159,298,362 - 159,301,568 (+)NCBIGRCr8
mRatBN7.24157,613,404 - 157,615,293 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4157,613,401 - 157,615,284 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4163,841,571 - 163,843,460 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04159,624,481 - 159,626,370 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04158,260,087 - 158,261,976 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04157,325,980 - 157,328,380 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4157,326,727 - 157,328,379 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl920,217,278 - 20,219,209 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04224,343,582 - 224,346,314 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44160,931,693 - 160,933,346 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14161,176,628 - 161,178,281 (+)NCBI
Celera4146,351,625 - 146,353,278 (+)NCBICelera
Cytogenetic Map4q42NCBI
SPSB2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38126,870,935 - 6,873,303 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl126,870,935 - 6,889,358 (-)EnsemblGRCh38hg38GRCh38
GRCh37126,980,099 - 6,982,467 (-)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map12p13.31NCBI
HuRef126,833,828 - 6,836,250 (-)NCBIHuRef
CHM1_1126,979,098 - 6,981,520 (-)NCBICHM1_1
T2T-CHM13v2.0126,880,233 - 6,882,601 (-)NCBIT2T-CHM13v2.0
Spsb2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396124,785,640 - 124,787,582 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6124,785,624 - 124,787,582 (+)EnsemblGRCm39 Ensembl
GRCm386124,808,604 - 124,810,619 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6124,808,661 - 124,810,619 (+)EnsemblGRCm38mm10GRCm38
MGSCv376124,758,959 - 124,760,632 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366124,774,560 - 124,776,233 (+)NCBIMGSCv36mm8
Celera6126,485,070 - 126,486,743 (+)NCBICelera
Cytogenetic Map6F2NCBI
cM Map659.17NCBI
SPSB2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12738,134,855 - 38,154,520 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2738,151,906 - 38,154,529 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha278,462,222 - 8,472,440 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02738,496,970 - 38,507,413 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2738,505,309 - 38,507,417 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12738,371,292 - 38,381,487 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02738,412,320 - 38,422,514 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0277,940,955 - 7,951,171 (-)NCBIUU_Cfam_GSD_1.0

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:153
Count of miRNA genes:120
Interacting mature miRNAs:126
Transcripts:ENSRNOT00000020493
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
737821Hcar9Hepatocarcinoma resistance QTL 93.7liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)4109866907167139601Rat
631683Bp116Blood pressure QTL 1160.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4124303370169303370Rat
737978Pia23Pristane induced arthritis QTL 235.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4131730738167139601Rat
6478718Anxrr34Anxiety related response QTL 340.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
6478748Anxrr42Anxiety related response QTL 420.28008locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
6478754Anxrr43Anxiety related response QTL 430.14035locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4144639524182687754Rat
6478778Anxrr51Anxiety related response QTL 510.25384locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4124778595169778595Rat
1298524Oia8Oil induced arthritis QTL 8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4138503169173369699Rat
6478693Anxrr32Anxiety related response QTL 320.00092locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4144639524182687754Rat
6478700Anxrr33Anxiety related response QTL 330.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
631511Pia7Pristane induced arthritis QTL 74.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4131730738167139601Rat
634342Cia24Collagen induced arthritis QTL 244.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4146565735175236377Rat
634347Hcar8Hepatocarcinoma resistance QTL 85.8liver integrity trait (VT:0010547)liver tumorous lesion area to total liver area ratio (CMO:0001075)4123143783168143783Rat
7411558Bw133Body weight QTL 13313.840.001body mass (VT:0001259)body weight gain (CMO:0000420)4125590636170590636Rat
1331738Bp209Blood pressure QTL 2092.979arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)4138503169179293946Rat
10053718Scort25Serum corticosterone level QTL 252.150.0097blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)4155561574182687754Rat
1358202Gluco11Glucose level QTL 112.40.02adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)485379421167139601Rat
1549827Scl46Serum cholesterol level QTL 463.5blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)4132396220177396220Rat
1581574Eae20Experimental allergic encephalomyelitis QTL 207.8nervous system integrity trait (VT:0010566)percentage of study population developing experimental autoimmune encephalomyelitis during a period of time (CMO:0001047)4153031106158841762Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)483428419177635233Rat
1578674Bmd12Bone mineral density QTL 123.8femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)4135699135180699135Rat
61362Oia2Oil induced arthritis QTL 20.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4138503169173369699Rat
61422Cia13Collagen induced arthritis QTL 134.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4132642577167139601Rat
724558Plsm2Polydactyly-luxate syndrome (PLS) morphotypes QTL 20.0003hindlimb integrity trait (VT:0010563)hind foot phalanges count (CMO:0001949)4132422778177422778Rat
2303623Vencon2Ventilatory control QTL 23.8respiration trait (VT:0001943)minute ventilation (CMO:0000132)4135204660180204660Rat
1331759Hrtrt13Heart rate QTL 133.54628heart pumping trait (VT:2000009)heart rate (CMO:0000002)4110275411168266883Rat
724535Cm18Cardiac mass QTL 182.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)4118856416163856416Rat
61451Ciaa4CIA Autoantibody QTL 43.1blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)4126395976167139601Rat
12798519Anxrr54Anxiety related response QTL 542.540.05locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4114627026159627026Rat
2293659Bmd35Bone mineral density QTL 354.50.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)4137755016181392681Rat
10401796Kidm48Kidney mass QTL 48kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)4145568712182687754Rat
12798525Anxrr57Anxiety related response QTL 573.210.05locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4147278504167139601Rat
634335Anxrr16Anxiety related response QTL 167.22locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)493308457167139447Rat
1582237Kidm34Kidney mass QTL 3440.0001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)4148090542168069246Rat

Markers in Region
RH143034  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24157,613,045 - 157,613,296 (-)MAPPERmRatBN7.2
mRatBN7.24157,613,045 - 157,613,296 (+)MAPPERmRatBN7.2
Rnor_6.04157,326,138 - 157,326,388NCBIRnor6.0
Rnor_6.0920,219,269 - 20,219,519NCBIRnor6.0
Rnor_5.04224,343,734 - 224,343,984UniSTSRnor5.0
Rnor_5.0919,095,245 - 19,095,495UniSTSRnor5.0
RGSC_v3.44160,931,104 - 160,931,354UniSTSRGSC3.4
Celera4146,351,036 - 146,351,286UniSTS
RH 3.4 Map41002.8UniSTS
Cytogenetic Map4q42UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium
Low 3 5 3 5 3 2 5 5 5 22 7 2
Below cutoff 3 39 55 33 22 33 14 17 67 34 34 12 14

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000020493   ⟹   ENSRNOP00000020493
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4157,613,622 - 157,615,284 (+)Ensembl
Rnor_6.0 Ensembl4157,326,727 - 157,328,379 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000072086   ⟹   ENSRNOP00000064453
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4157,613,401 - 157,615,277 (+)Ensembl
Rnor_6.0 Ensembl920,217,278 - 20,219,209 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000114293   ⟹   ENSRNOP00000084808
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4157,613,730 - 157,615,283 (+)Ensembl
RefSeq Acc Id: NM_001009660   ⟹   NP_001009660
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84159,299,874 - 159,301,568 (+)NCBI
mRatBN7.24157,613,599 - 157,615,293 (+)NCBI
Rnor_6.04157,326,727 - 157,328,380 (+)NCBI
Rnor_5.04224,343,582 - 224,346,314 (+)NCBI
RGSC_v3.44160,931,693 - 160,933,346 (+)RGD
Celera4146,351,625 - 146,353,278 (+)RGD
Sequence:
RefSeq Acc Id: NM_001394356   ⟹   NP_001381285
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84159,299,679 - 159,301,568 (+)NCBI
mRatBN7.24157,613,404 - 157,615,293 (+)NCBI
RefSeq Acc Id: NM_001394357   ⟹   NP_001381286
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84159,299,874 - 159,301,568 (+)NCBI
mRatBN7.24157,613,599 - 157,615,293 (+)NCBI
RefSeq Acc Id: XM_063285904   ⟹   XP_063141974
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84159,299,815 - 159,301,565 (+)NCBI
RefSeq Acc Id: XM_063285905   ⟹   XP_063141975
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84159,298,362 - 159,301,565 (+)NCBI
RefSeq Acc Id: XM_063285906   ⟹   XP_063141976
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84159,299,843 - 159,301,565 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001009660   ⟸   NM_001009660
- UniProtKB: Q5M877 (UniProtKB/Swiss-Prot),   A6ILL1 (UniProtKB/TrEMBL),   A0A8I5ZYR0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000020493   ⟸   ENSRNOT00000020493
RefSeq Acc Id: ENSRNOP00000064453   ⟸   ENSRNOT00000072086
RefSeq Acc Id: ENSRNOP00000084808   ⟸   ENSRNOT00000114293
RefSeq Acc Id: NP_001381285   ⟸   NM_001394356
- UniProtKB: Q5M877 (UniProtKB/Swiss-Prot),   A6ILL1 (UniProtKB/TrEMBL),   A0A8I5ZYR0 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001381286   ⟸   NM_001394357
- UniProtKB: Q5M877 (UniProtKB/Swiss-Prot),   A6ILL1 (UniProtKB/TrEMBL),   A0A8I5ZYR0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141975   ⟸   XM_063285905
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063141974   ⟸   XM_063285904
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063141976   ⟸   XM_063285906
- Peptide Label: isoform X1
Protein Domains
B30.2/SPRY   SOCS box

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5M877-F1-model_v2 AlphaFold Q5M877 1-264 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693389
Promoter ID:EPDNEW_R3914
Type:initiation region
Name:LOC100911548_1
Description:SPRY domain-containing SOCS box protein 2-like
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04157,326,698 - 157,326,758EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310854 AgrOrtholog
BioCyc Gene G2FUF-43067 BioCyc
Ensembl Genes ENSRNOG00000015125 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00000047113 Ensembl
  ENSRNOG00055010547 UniProtKB/Swiss-Prot
  ENSRNOG00060032523 UniProtKB/Swiss-Prot
  ENSRNOG00065029467 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000020493 ENTREZGENE
  ENSRNOT00000020493.6 UniProtKB/Swiss-Prot
  ENSRNOT00000072086.3 UniProtKB/TrEMBL
  ENSRNOT00000114293.1 UniProtKB/TrEMBL
  ENSRNOT00055017871 UniProtKB/Swiss-Prot
  ENSRNOT00060056348 UniProtKB/Swiss-Prot
  ENSRNOT00065050889 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.120.920 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SOCS box UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7371446 IMAGE-MGC_LOAD
InterPro B30.2/SPRY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  B30.2/SPRY_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ConA-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SOCS_box UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SOCS_box-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SPRY_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSB2_SOCS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:297592 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:108858 IMAGE-MGC_LOAD
NCBI Gene 297592 ENTREZGENE
PANTHER SPRY DOMAIN CONTAINING SOCS BOX PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SPRY DOMAIN-CONTAINING SOCS BOX PROTEIN 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam SOCS_box UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SPRY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Spsb2 PhenoGen
PROSITE B302_SPRY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SOCS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000015125 RatGTEx
  ENSRNOG00000047113 RatGTEx
  ENSRNOG00055010547 RatGTEx
  ENSRNOG00060032523 RatGTEx
  ENSRNOG00065029467 RatGTEx
SMART SOCS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SOCS_box UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SPRY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SOCS box-like UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
  SSF49899 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZYR0 ENTREZGENE, UniProtKB/TrEMBL
  A6ILL1 ENTREZGENE, UniProtKB/TrEMBL
  Q5M877 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Spsb2  splA/ryanodine receptor domain and SOCS box containing 2  LOC100911548  SPRY domain-containing SOCS box protein 2-like  Data merged from RGD:6492498 737654 PROVISIONAL
2012-07-05 LOC100911548  SPRY domain-containing SOCS box protein 2-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-03-30 Spsb2  splA/ryanodine receptor domain and SOCS box containing 2  Grcc9  gene rich cluster, C9 gene  Symbol and Name updated 1299863 APPROVED
2005-12-06 Grcc9  gene rich cluster, C9 gene  Grcc9_predicted  gene rich cluster, C9 gene (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Grcc9_predicted  gene rich cluster, C9 gene (predicted)      Symbol and Name status set to approved 70820 APPROVED