Recql5 (RecQ like helicase 5) - Rat Genome Database

Name: Recql5
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Recql5 (RecQ like helicase 5) Rattus norvegicus

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Symbol:

Recql5

Name:

RecQ like helicase 5

RGD ID:

1310823

Description:

Predicted to enable DNA helicase activity; RNA polymerase II complex binding activity; and identical protein binding activity. Predicted to be involved in DNA metabolic process; chromosome separation; and negative regulation of transcription elongation by RNA polymerase II. Predicted to act upstream of or within several processes, including cellular response to camptothecin; negative regulation of double-strand break repair via homologous recombination; and replication-born double-strand break repair via sister chromatid exchange. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of transcription preinitiation complex. Predicted to be active in cytoplasm and replication fork. Orthologous to human RECQL5 (RecQ like helicase 5); INTERACTS WITH 2,6-dinitrotoluene; furan; thioacetamide.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

ATP-dependent DNA helicase Q5; DNA 3'-5' helicase RecQ5; DNA helicase, RecQ-like type 5; LOC287834; RecQ helicase-like 5; RecQ protein-like 5; RecQ5

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	RECQL5 (RecQ like helicase 5)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Recql5 (RecQ protein-like 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Recql5 (RecQ like helicase 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	RECQL5 (RecQ like helicase 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	RECQL5 (RecQ like helicase 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Recql5 (RecQ like helicase 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	RECQL5 (RecQ like helicase 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	RECQL5 (RecQ like helicase 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Recql5 (RecQ like helicase 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	RECQL5 (RecQ like helicase 5)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Recql5 (RecQ protein-like 5)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	recql5 (RecQ helicase-like 5)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	rcq-5	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	RecQ5	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	101,625,477 - 101,664,582 (-)	NCBI		GRCr8
mRatBN7.2	10	101,126,544 - 101,165,739 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	101,126,547 - 101,165,652 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	106,188,129 - 106,227,225 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	105,651,217 - 105,690,313 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	101,047,510 - 101,086,610 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	104,443,735 - 104,482,889 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	104,443,736 - 104,482,838 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	103,802,475 - 103,841,704 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	106,000,185 - 106,039,287 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	106,015,032 - 106,053,330 (-)	NCBI
Celera	10	99,701,483 - 99,740,586 (-)	NCBI		Celera
Cytogenetic Map	10	q32.1	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

myoepithelioma (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,6-dinitrotoluene (EXP)

4,4'-sulfonyldiphenol (ISO)

5-aza-2'-deoxycytidine (ISO)

acrylamide (ISO)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

all-trans-retinoic acid (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

benzo[e]pyrene (ISO)

bisphenol F (ISO)

cadmium dichloride (ISO)

caffeine (ISO)

chlorpyrifos (ISO)

clofibrate (ISO)

coumarin (ISO)

cyclosporin A (ISO)

cytarabine (ISO)

Dibutyl phosphate (ISO)

doxorubicin (ISO)

elemental selenium (ISO)

FR900359 (ISO)

fulvestrant (ISO)

furan (EXP)

leflunomide (ISO)

methapyrilene (ISO)

methylmercury chloride (ISO)

paracetamol (ISO)

pentanal (ISO)

pirinixic acid (ISO)

selenium atom (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

thioacetamide (EXP)

thiram (ISO)

trimellitic anhydride (ISO)

triptonide (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell division (IEA)

cellular response to camptothecin (ISO)

cellular response to xenobiotic stimulus (ISO)

chromatin looping (IEA)

chromatin remodeling (IEA)

chromosome separation (ISO,ISS)

DNA recombination (IEA)

DNA repair (ISO,ISS)

DNA replication (IEA,ISO,ISS)

DNA unwinding involved in DNA replication (IBA)

double-strand break repair via homologous recombination (IBA)

mitotic cell cycle (ISO,ISS)

mitotic DNA-templated DNA replication (ISO)

negative regulation of double-strand break repair via homologous recombination (ISO)

negative regulation of transcription elongation by RNA polymerase II (ISO,ISS)

regulation of DNA-templated transcription (IEA)

replication-born double-strand break repair via sister chromatid exchange (ISO)

Cellular Component

chromosome (IBA,IEA)

cytoplasm (IBA)

cytosol (IEA,ISO)

nucleoplasm (IEA,ISO)

nucleus (IEA,ISO,ISS)

replication fork (ISO)

transcription preinitiation complex (ISO)

Molecular Function

3'-5' DNA helicase activity (IBA)

ATP binding (IEA)

ATP hydrolysis activity (IEA)

ATP-dependent H2AZ histone chaperone activity (IEA)

ATP-dependent H3-H4 histone complex chaperone activity (IEA)

chromatin extrusion motor activity (IEA)

cohesin loader activity (IEA)

DNA binding (IEA)

DNA clamp loader activity (IEA)

DNA helicase activity (ISO,ISS)

double-stranded DNA helicase activity (IEA)

forked DNA-dependent helicase activity (IEA)

four-way junction helicase activity (IBA)

helicase activity (IEA,ISO)

hydrolase activity (IEA)

identical protein binding (ISO)

isomerase activity (IEA)

metal ion binding (IEA)

nucleic acid binding (IEA)

protein binding (ISO)

RNA polymerase II complex binding (ISO,ISS)

single-stranded 3'-5' DNA helicase activity (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:22013166	PMID:22231121	PMID:22973052	PMID:23748380	PMID:25520194

Genomics

Comparative Map Data

Recql5
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	101,625,477 - 101,664,582 (-)	NCBI		GRCr8
mRatBN7.2	10	101,126,544 - 101,165,739 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	101,126,547 - 101,165,652 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	106,188,129 - 106,227,225 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	105,651,217 - 105,690,313 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	101,047,510 - 101,086,610 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	104,443,735 - 104,482,889 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	104,443,736 - 104,482,838 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	103,802,475 - 103,841,704 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	106,000,185 - 106,039,287 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	106,015,032 - 106,053,330 (-)	NCBI
Celera	10	99,701,483 - 99,740,586 (-)	NCBI		Celera
Cytogenetic Map	10	q32.1	NCBI

RECQL5
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	75,626,854 - 75,667,154 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	17	75,626,845 - 75,667,189 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	17	73,622,934 - 73,663,234 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	71,134,545 - 71,174,864 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	17	71,134,519 - 71,174,864	NCBI
Celera	17	70,213,035 - 70,253,352 (-)	NCBI		Celera
Cytogenetic Map	17	q25.1	NCBI
HuRef	17	69,046,776 - 69,087,094 (-)	NCBI		HuRef
CHM1_1	17	73,687,648 - 73,727,993 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	17	76,520,039 - 76,560,340 (-)	NCBI		T2T-CHM13v2.0

Recql5
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	115,783,421 - 115,824,339 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	115,783,421 - 115,824,303 (-)	Ensembl		GRCm39 Ensembl
GRCm38	11	115,892,595 - 115,933,514 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	115,892,595 - 115,933,477 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	115,753,991 - 115,794,320 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	115,708,767 - 115,749,096 (-)	NCBI		MGSCv36	mm8
Celera	11	127,655,372 - 127,696,066 (-)	NCBI		Celera
Cytogenetic Map	11	E2	NCBI
cM Map	11	80.91	NCBI

Recql5
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955506	6,575,408 - 6,612,186 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955506	6,574,802 - 6,612,763 (+)	NCBI	ChiLan1.0	ChiLan1.0

RECQL5
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	19	91,671,332 - 91,711,674 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	17	96,495,884 - 96,536,231 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	69,577,778 - 69,618,068 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	75,128,325 - 75,168,254 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	75,128,325 - 75,168,254 (-)	Ensembl	panpan1.1		panPan2

RECQL5
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	4,902,753 - 4,940,442 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	4,903,477 - 4,940,436 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	5,582,993 - 5,620,685 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	5,573,773 - 5,611,450 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	5,573,825 - 5,611,417 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	5,613,194 - 5,650,847 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	5,723,100 - 5,760,763 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	5,784,163 - 5,821,891 (+)	NCBI		UU_Cfam_GSD_1.0

Recql5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	5,549,044 - 5,582,663 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936594	828,475 - 862,912 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936594	829,296 - 862,615 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RECQL5
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	5,732,348 - 5,770,133 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	12	5,732,336 - 5,770,136 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	12	5,678,744 - 5,694,092 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RECQL5
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	46,013,100 - 46,052,713 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	16	46,013,092 - 46,056,167 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666077	16,772,793 - 16,812,945 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Recql5
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624801	5,530,992 - 5,567,628 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624801	5,530,411 - 5,568,355 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Recql5
135 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	264
Count of miRNA genes:	157
Interacting mature miRNAs:	184
Transcripts:	ENSRNOT00000007246
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1354641	Bvd2	Brain ventricular dilatation QTL 2	6.36	0.001	brain ventricle morphology trait (VT:0000822)	hydrocephalus severity score (CMO:0001881)	10	93223816	107057807	Rat
61449	Ciaa2	CIA Autoantibody QTL 2	7.1		blood autoantibody amount (VT:0003725)	calculated serum anti-type 2 collagen antibody titer (CMO:0001279)	10	63221094	107211142	Rat
61325	Aia5	Adjuvant induced arthritis QTL 5		0.01	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23444813	104060283	Rat
1298078	Stresp5	Stress response QTL 5	2.99	0.00025	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	10	42045676	104670812	Rat
1549831	Bss6	Bone structure and strength QTL 6	4		lumbar vertebra strength trait (VT:0010574)	vertebra ultimate force (CMO:0001678)	10	57576521	102576521	Rat
1579915	Bp280	Blood pressure QTL 280		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	90404397	107211142	Rat
2298548	Neuinf7	Neuroinflammation QTL 7	3.4		nervous system integrity trait (VT:0010566)	spinal cord RT1-B protein level (CMO:0002132)	10	72224939	107211142	Rat
1302404	Cia27	Collagen induced arthritis QTL 27	2.6	0.0045	joint integrity trait (VT:0010548)	experimental arthritis severity measurement (CMO:0001459)	10	76452683	107211142	Rat
2317754	Glom25	Glomerulus QTL 25	3.5		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	10	82685200	107211142	Rat
70171	Cari1	Carrageenan-induced inflammation QTL 1	4.9	0.0005	hypodermis integrity trait (VT:0010550)	inflammatory exudate volume (CMO:0001429)	10	53797385	107211142	Rat
10450493	Bp382	Blood pressure QTL 382		0.002	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	94759759	107211142	Rat
1578672	Bmd16	Bone mineral density QTL 16	6.2		femur mineral mass (VT:0010011)	compact volumetric bone mineral density (CMO:0001730)	10	96703043	107057807	Rat
61354	Pia10	Pristane induced arthritis QTL 10		0.01	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23444813	104060283	Rat
2293646	Bss25	Bone structure and strength QTL 25	10.96	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	10	69738412	107211142	Rat
2313103	Bss80	Bone structure and strength QTL 80	2	0.0001	tibia strength trait (VT:1000284)	tibia midshaft endosteal cross-sectional area (CMO:0001716)	10	62057807	107057807	Rat
2303118	Mamtr7	Mammary tumor resistance QTL 7		0.003	mammary gland integrity trait (VT:0010552)	mammary tumor growth rate (CMO:0000344)	10	9658275	104670812	Rat
2300172	Bmd57	Bone mineral density QTL 57	9.8	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	10	69738412	107211142	Rat
70193	Mcs7	Mammary carcinoma susceptibility QTL 7	2.38		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	10	72224939	107211142	Rat
2313105	Bss79	Bone structure and strength QTL 79	1.8	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	10	62057807	107057807	Rat
61363	Oia3	Oil induced arthritis QTL 3		0.001	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	87307617	107211142	Rat
2316949	Gluco60	Glucose level QTL 60	3.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	10	14487011	107057807	Rat
724530	Bp149	Blood pressure QTL 149		0.0001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	90627439	107211142	Rat
1300137	Bp186	Blood pressure QTL 186	3.57		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	10	90627439	107057807	Rat
2293663	Bss33	Bone structure and strength QTL 33	9.34	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	10	69738412	107211142	Rat
1578663	Bss18	Bone structure and strength QTL 18	3.6		femur width (VT:1000666)	femoral neck width (CMO:0001695)	10	96703043	107057807	Rat
7387312	Bw125	Body weight QTL 125	3	0.0047	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight (CMO:0000356)	10	64890616	107211142	Rat
2312672	Insul15	Insulin level QTL 15		0.01	blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	10	57134272	102134272	Rat
6893357	Bw102	Body weight QTL 102	0.5	0.36	body mass (VT:0001259)	body weight (CMO:0000012)	10	80515287	101325465	Rat
12880384	Cm107	Cardiac mass QTL 107		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)		90404397	107211142	Rat
12880385	Cm108	Cardiac mass QTL 108		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)		90404397	107211142	Rat
2303589	Bw87	Body weight QTL 87	2		body mass (VT:0001259)	body weight (CMO:0000012)	10	81285008	107211142	Rat
2317029	Aia19	Adjuvant induced arthritis QTL 19	2.98		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	10	66978955	107211142	Rat
12880396	Am13	Aortic mass QTL 13		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	10	90404397	107211142	Rat
12880398	Kidm67	Kidney mass QTL 67		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	10	90404397	107211142	Rat
61387	Bp1	Blood pressure QTL 1	5.1		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	10	51770177	107211142	Rat
2317039	Aia6	Adjuvant induced arthritis QTL 6	4.31		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	10	66978955	107211142	Rat
12880395	Cm109	Cardiac mass QTL 109		0.001	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	10	90404397	107211142	Rat
61396	Bp9	Blood pressure QTL 9	4.8	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	68420376	107211142	Rat
634320	Niddm49	Non-insulin dependent diabetes mellitus QTL 49	4.41		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	10	88539139	107211142	Rat
1331791	Cm31	Cardiac mass QTL 31	3.84606		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	10	29299504	107211142	Rat
10450498	Bp384	Blood pressure QTL 384		0.002	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	67750049	107211142	Rat
4889492	Pancm2	Pancreatic morphology QTL 2	3.2		pancreatic beta cell morphology trait (VT:0005217)	ratio of insulin-positive cell area to total area of splenic region of pancreas (CMO:0001814)	10	76748906	107211142	Rat
6893366	Bw106	Body weight QTL 106	0.3	0.47	body mass (VT:0001259)	body weight (CMO:0000012)	10	70199100	107211142	Rat
2293698	Bss43	Bone structure and strength QTL 43	5.33	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra cross-sectional area (CMO:0001689)	10	59209888	104209888	Rat
1576313	Pia25	Pristane induced arthritis QTL 25			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	96120911	104060283	Rat
631267	Cia20	Collagen induced arthritis QTL 20	3.2		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23444813	104060283	Rat
1576307	Cia28	Collagen induced arthritis QTL 28			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	96120911	104060283	Rat
631269	Cia22	Collagen induced arthritis QTL 22	8.9		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	40035094	104060283	Rat
1576308	Schws1	Schwannoma susceptibility QTL 1		0.0041	nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	10	40035094	102359817	Rat
631268	Cia21	Collagen induced arthritis QTL 21	3.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	14487011	104060283	Rat
631270	Cia23	Collagen induced arthritis QTL 23	3.9		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	40035094	104060283	Rat
2292438	Bp311	Blood pressure QTL 311			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	76246085	107211142	Rat
2312662	Slep8	Serum leptin concentration QTL 8		0.05	blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	10	57134272	102134272	Rat
2292436	Bp310	Blood pressure QTL 310			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	94759759	107211142	Rat
1600367	Mcs15	Mammary carcinoma susceptibility QTL 15	4.5		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	10	85565469	103884409	Rat
631539	Oia6	Oil induced arthritis QTL 6			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	97010147	104670812	Rat
631538	Oia5	Oil induced arthritis QTL 5			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	87055121	107211142	Rat
61436	Cia5	Collagen induced arthritis QTL 5	4.9		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	91228102	104060283	Rat
1642980	Bp300	Blood pressure QTL 300			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	68383129	107211142	Rat
2312668	Scl65	Serum cholesterol level QTL 65		0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	10	57134272	102134272	Rat

Markers in Region

RH128394

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	10	101,126,624 - 101,126,814 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	104,443,814 - 104,444,003	NCBI	Rnor6.0
Rnor_5.0	10	103,841,436 - 103,841,625	UniSTS	Rnor5.0
RGSC_v3.4	10	106,000,263 - 106,000,452	UniSTS	RGSC3.4
Celera	10	99,701,561 - 99,701,750	UniSTS
Cytogenetic Map	10	q32.3	UniSTS

RH142484

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	10	101,164,535 - 101,164,656 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	104,481,722 - 104,481,842	NCBI	Rnor6.0
Rnor_5.0	10	103,803,519 - 103,803,639	UniSTS	Rnor5.0
RGSC_v3.4	10	106,038,171 - 106,038,291	UniSTS	RGSC3.4
Celera	10	99,739,470 - 99,739,590	UniSTS
Cytogenetic Map	10	q32.3	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001105853	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017597161	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039085674	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039085675	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039085676	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005489766	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC130970	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473948	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ226779	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000007246 ⟹ ENSRNOP00000007246

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	10	101,126,547 - 101,165,652 (-)	Ensembl
Rnor_6.0 Ensembl	10	104,443,736 - 104,482,838 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000104127 ⟹ ENSRNOP00000096399

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	10	101,126,547 - 101,165,652 (-)	Ensembl

RefSeq Acc Id:

NM_001105853 ⟹ NP_001099323

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	101,625,480 - 101,664,582 (-)	NCBI
mRatBN7.2	10	101,126,547 - 101,165,652 (-)	NCBI
Rnor_6.0	10	104,443,736 - 104,482,838 (-)	NCBI
Rnor_5.0	10	103,802,475 - 103,841,704 (+)	NCBI
RGSC_v3.4	10	106,000,185 - 106,039,287 (-)	RGD
Celera	10	99,701,483 - 99,740,586 (-)	RGD

Sequence:

show sequence

TCGCTGGCTACTCGGGCGGTTTGGTTTCTGAGTTAGAATTAGGGAGTAGTGTTCTTTAAAAAGC
TGCAGAGCCAACCGAAAAGAGCCTGGGGTCTGACATCTTAGGGAGCATTTGGCTGGCGAAGGGC
GAAACCTGTTGACTTGGGGCCCAGAGGAAGGGGGGCTCGGCATCCTGTAAGGGAGAGTGGTCTC
TATGGCTTTGCTTCTAGAACAAGGACCCTAGAAAAAGGATTCCAAGTTCTCCAGTCGGATCTGA
AGACGTTTGCGGGCTTTGTTGTGGTTCAGTTTCTAGTTCTGTTCCACTGACCTGGAAAGTTCAT
TGTTTTTATTTTCATTAAAGGGAGAAGTGATGTTAACTCCTCAGGGATGTATTGCGTGAAGCAA
TTCAACCTTCACTTTTACTGCTGGAGAATGATATATTTAAGCGTAACATAGCAGATTATACTGC
AGAAGAAACAAAGGCTATATTTTAAAGCGGAGCAGGGGGTTTCCTGGGATAACCTTTGACTACC
TTTGCATTCACCTTTTGGCTGCTGCTTTTTGCAAAGATGAGCGCCCGTCCTTTCTCCACTCCCT
TCGACCGGGAGCGGCGAGTCCGGAGCACCCTGAAGAAAGTCTTTGGGTTTGATTCTTTTAAAAC
ACCTTTACAAGAGAGTGCGATCATGGCTGTAGTGAAAGGTGACAAGGATGTGTTTGTGTGCATG
CCCACAGGGGCAGGGAAATCTCTGTGCTATCAGCTCCCTGCCGTGCTGGCTAAAGGGATCACCA
TTGTGGTCTCTCCTCTCATTGCCTTGATTCAGGACCAGGTAGACCACTTGCTGGCCTTGAAGGT
ACAAGTTAGTTCTCTGAACTCAAAGCTCTCAGTACAGGAGAGGAAGGAGCTGCTGTCTGACCTG
GAGCGAGACAAACCTCGGACCAAACTTCTGTACATCACCCCGGAGATGGCAGCTTCAGCCTCCT
TCCAGCCCACCCTGAATTCCCTCCTGTCCCGAAACCTGCTCTCCTACTTGGTGGTGGATGAAGC
TCATTGCGTTTCCCAGTGGGGACACGACTTCCGGCCTGACTATCTGCGTCTGGGCGCCCTACGT
TCCCGCTTAGCACATGCCCCGTGCGTGGCTCTGACAGCTACAGCCACCCCACAGGTTCAAGAGG
ATGTGTTTGCTGCCCTGCACTTGAAGCAGCCAGTGGCCTCTTTCAAGACTCCCTGTTTCCGGGC
CAATCTCTTCTATGATGTGCAGTTCAAGGAACTGATTCCTGACGTCTATGGCAATCTGAGGGAC
TTCTGCCTTAAGGCCCTTGGACAGAAGGCTGATAACGGGTCGTCATCTGGCTGTGGCATTGTCT
ACTGCAGGACTAGAGAAGCTTGTGAACAACTGGCCATTGAGCTCAGCAGCAGGGGTGTGAATGC
CAAGGCTTACCATGCAGGCCTGAAGGCTTCTGAGAGAACGCAGGTACAGAATGAGTGGATGGAG
GAGAAGGTCCCTGTGATTGTGGCAACCATCAGTTTTGGGATGGGAGTGGATAAAGCTAATGTCC
GGTTTGTTGCTCATTGGAATATCGCCAAGTCCATGGCTGGCTACTACCAGGAGTCTGGCCGTGC
TGGCAGGGATGGTAAACCATCTTGGTGCCGCCTCTATTACTCTAGGAATGACCGAGACCAAGTC
AGCTTCCTTATCAGGAAGGAACTAGCCAAACTCCAGGAAAAGAGGGGGAACAAACCATCTGATA
AGGCTACCTTGCTGGCCTTTGATGCCCTGGTGACCTTCTGTGAAGAAGTAGGGTGCCGCCATGC
CGCCATCGCTAAGTACTTTGGGGATGCGCCACCCGCCTGCGCCAAAGGCTGTGACTGTTGCCAG
AGCCCTGCAGCCATAAGGAAGAAGCTTGATGCCCTGGAGCACAGCAGCAGCTGGGGCAAGACCT
GCATCGGGCCCTCGCAGGGGGACGGCTTCGATCCTGAGCTGTATGAGGGAGGCCGCCGGGGCTA
CGGGGGCTTCAGCAGGTATGATGAAGGTTCCGGAGGCAGCGGTGATGAGGGCAGAGATGAGGCT
CATAAGAGAGAGTGGAATCTTTTCTATCAGAGACAGATGAGCCTGCGCAAGGGCAAAGAGGCCA
AGCCAGAAGAATTCACACCCCCAGGTGAAGACTGTCCCCTGAGAGATGCTTCAAGCAGGAAGAT
CCCTAAGCTCACAGTGAAGGCCCGTGAGCACTGCCTGAGACTTCTGGAGGAGGCTCTGAACAGT
AACCACCAGGCTGCAGGGTCCACTCACGGAGCTGACCTACAGGCCAAGGCTGTGGAACTGGAGC
ATGAGACATTCCGAAGTGCCAAGATGGTCAATCTGTACAAGGCCAGTGTTCTCAAGAAGGTGGC
TGAGATCCACAAAGCCTCCAAGGACGGTCAGCTCTATGACATGGAAAGCAGCACCAAGAGCTGT
GGGGCCATAGCTGAGCTCTTGGAGCCCAGTGACTATGACATCCCGCCAACCTCACATTTGTACT
CGCTCAAACCCAAGAGAGTAGGAGCTGGCTTCTCTAAAGGCCCCTGCCCATTCCAGACAGCCAC
AGAACTGTTGGGCAAGTCTCAGACCGAGAAGCTGGCCCCAGAGGCTGCACTGGAGAGTGAACAG
GAGCCCTCAGGCTGGGTCTGTGATCCTCAAGATGGAGACAGGAGCAAGCCCTGCCTTGGGTACC
AAGAGGAAGCTCCTGGAAGCAGGACTAATTGTGGGGATCCCTCACCTGAGAAGAGGACAAAAGG
CTCTTCCCAGGGCAGTGCCAAGGCTAGGGCCAGCAAGAGACAGCAGCTCTTAGCCACAGCAGCC
CGCAAGGACTCCCAGAGTATCACCCGATTCCTCCGTCAGAGAACAGAATGCCCGCCACCCGCTG
CTTCCGTCCCCAGTTCAGAAGATGCCAGCCCCTGTGGGGATGTCCCAGGGAAGTGCACAGAAGA
AGTTGGAGCCCAGGGACATTTGGTGGCTGTATTTCAGACTGAGTGTCCCAGGGAGAGGCTAAGC
ACCTGCTCACTTGAAGACCAGAGCCTCCCCAAAGGTCAGCCTAGCCCTCTAAAGGAAACCCAGG
CGGAGAAGAGGCCCAGACCACAGCAGGAAAGCCAAGAGAAGAGGGCTCAGAAGAGGCTTCGCCC
CTCAACCAACTCTTCCGCCTTGGCCAGTGACCCCAGCACCGAGAACAGAGTGGCTCGCGAACCT
TGCCAGCTCTCAGCTCCTGGCATCTCCCTGAAAGAGGCTGCAGACATTGTGGTCAGGTACCTGA
CCCCCTTCTACAAGGAGGGCAGGTTTATATCCAAGGACTTGTTCAAGGGCTTTGCCCGCCACCT
CTCACATTTGCTGGCTCAGAAGCTCTCTCCTGGAAGGAGTGTGAAGGAAGAGGCCCAGAGCCTA
ATCAAGCAGTTCTTCCACAACCGTGCCCGGTGCGAGAGTGAAGCTGACTGGCATGGCCTGTGTG
GCCCACAGCGATGACTGAACAATGCCTGCGTCTCCCTCTTGCCCTCTGTGCCACAGGCACCAGC
TTTCTCAGGGTCTTTCTCTCCGTGAACAAACCTCACTGGAGGTCAGAAGTCAGCACACCTTCCT
ATTTAAGACCCTCCTGGTCCTCTGACAGCCTGCTTTCCTGGCCGGCCTTCATGGCCAGATCTCC
AGATACGAAGGTCCAGATAATATGGCTGCTGCCAAAGGGGAGGTTGTGTATGTGTGTGTGTCGG
GGGACCAATGGTCCTCCTGTCTTGTAGCTAAGTTCTCTATCAGGGTGGGGCCCACTCCAGTTCT
CCACTGCCCTCTTCTATGAGATGTCGGCCTGTAGACCTTGTCCCAGCAGAGCTCACTGGGAGAG
AAGCTCTGCAGCTCAGGAAGGCCAGGCCCAAGTGAGATATGCAAGAATAAAGTCCTTGTGGAGA
C

hide sequence

RefSeq Acc Id:

XM_017597161 ⟹ XP_017452650

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	101,625,477 - 101,664,037 (-)	NCBI
mRatBN7.2	10	101,126,544 - 101,165,739 (-)	NCBI
Rnor_6.0	10	104,443,735 - 104,482,889 (-)	NCBI

Sequence:

show sequence

CTTGGAAACGTCATCAGCACGGGACGGAAGTAAGGTTTTGCGGCTTCTACTTCGCTGGCTACTC
GGGCGGTTTGGTTTCTGAGTTAGAATTAGGGAGTAGTGTTCTTTAAAAAGCTGCAGAGCCAACC
GAAAAGAGCCTGGGGTCTGACATCTTAGGGAGCATTTGGCTGGCGAAGGGCGAAACCTGTTGAC
TTGGGGCCCAGAGGAAGGGGGGCTCGGCATCCTGTAAGGGAGAGTGGTCTCTATGGCTTTGCTT
CTAGAACAAGGACCCTAGAAAAAGGATTCCAAGTTCTCCAGTCGGATCTGAAGACGTTTGCGGG
CTTTGTTGTGGTTCAGTTTCTAGTTCTGTTCCACTGACCTGGAAAGTTCATTGTTTTTATTTTC
ATTAAAGGGAGAAGTGATGTTAACTCCTCAGGGATGTATTGCGTGAAGCAATTCAACCTTCACT
TTTACTGCTGGAGAATGATATATTTAAGCGTAACATAGCAGATTATACTGCAGAAGAAACAAAG
GCTATATTTTAAAGCGGAGCAGGGGGTTTCCTGGGATAACCTTTGACTACCTTTGCATTCACCT
TTTGGCTGCTGCTTTTTGCAAAGATGAGCGCCCGTCCTTTCTCCACTCCCTTCGACCGGGAGCG
GCGAGTCCGGAGCACCCTGAAGAAAGTCTTTGGGTTTGATTCTTTTAAAACACCTTTACAAGAG
AGTGCGATCATGGCTGTAGTGAAAGGTGACAAGGATGTGTTTGTGTGCATGCCCACAGGGGCAG
GGAAATCTCTGTGCTATCAGCTCCCTGCCGTGCTGGCTAAAGGGATCACCATTGTGGTCTCTCC
TCTCATTGCCTTGATTCAGGACCAGGTAGACCACTTGCTGGCCTTGAAGGTACAAGTTAGTTCT
CTGAACTCAAAGCTCTCAGTACAGGAGAGGAAGGAGCTGCTGTCTGACCTGGAGCGAGACAAAC
CTCGGACCAAACTTCTGTACATCACCCCGGAGATGGCAGCTTCAGCCTCCTTCCAGCCCACCCT
GAATTCCCTCCTGTCCCGAAACCTGCTCTCCTACTTGGTGGTGGATGAAGCTCATTGCGTTTCC
CAGTGGGGACACGACTTCCGGCCTGACTATCTGCGTCTGGGCGCCCTACGTTCCCGCTTAGCAC
ATGCCCCGTGCGTGGCTCTGACAGCTACAGCCACCCCACAGGTTCAAGAGGATGTGTTTGCTGC
CCTGCACTTGAAGCAGCCAGTGGCCTCTTTCAAGACTCCCTGTTTCCGGGCCAATCTCTTCTAT
GATGTGCAGTTCAAGGAACTGATTCCTGACGTCTATGGCAATCTGAGGGACTTCTGCCTTAAGG
CCCTTGGACAGAAGGCTGATAACGGGTCGTCATCTGGCTGTGGCATTGTCTACTGCAGGACTAG
AGAAGCTTGTGAACAACTGGCCATTGAGCTCAGCAGCAGGGGTGTGAATGCCAAGGCTTACCAT
GCAGGCCTGAAGGCTTCTGAGAGAACGCAGGTACAGAATGAGTGGATGGAGGAGAAGGTCCCTG
TGATTGTGGCAACCATCAGTTTTGGGATGGGAGTGGATAAAGCTAATGTCCGGTTTGTTGCTCA
TTGGAATATCGCCAAGTCCATGGCTGGCTACTACCAGGAGTCTGGCCGTGCTGGCAGGGATGGT
AAACCATCTTGGTGCCGCCTCTATTACTCTAGGAATGACCGAGACCAAGTCAGCTTCCTTATCA
GGAAGGAACTAGCCAAACTCCAGGAAAAGAGGGGGAACAAACCATCTGATAAGGCTACCTTGCT
GGCCTTTGATGCCCTGGTGACCTTCTGTGAAGAAGTAGGGTGCCGCCATGCCGCCATCGCTAAG
TACTTTGGGGATGCGCCACCCGCCTGCGCCAAAGGCTGTGACTGTTGCCAGAGCCCTGCAGCCA
TAAGGAAGAAGCTTGATGCCCTGGAGCACAGCAGCAGCTGGGGCAAGACCTGCATCGGGCCCTC
GCAGGGGGACGGCTTCGATCCTGAGCTGTATGAGGGAGGCCGCCGGGGCTACGGGGGCTTCAGC
AGGTATGATGAAGGTTCCGGAGGCAGCGGTGATGAGGGCAGAGATGAGGCTCATAAGAGAGAGT
GGAATCTTTTCTATCAGAGACAGATGAGCCTGCGCAAGGGCAAAGAGGCCAAGCCAGAAGAATT
CACACCCCCAGGTGAAGACTGTCCCCTGAGAGATGCTTCAAGCAGGAAGATCCCTAAGCTCACA
GTGAAGGCCCGTGAGCACTGCCTGAGACTTCTGGAGGAGGCTCTGAACAGTAACCACCAGGCTG
CAGGGTCCACTCACGGAGCTGACCTACAGGCCAAGGCTGTGGAACTGGAGCATGAGACATTCCG
AAGTGCCAAGATGGTCAATCTGTACAAGGCCAGTGTTCTCAAGAAGGTGGCTGAGATCCACAAA
GCCTCCAAGGACGGTCAGCTCTATGACATGGAAAGCAGCACCAAGAGCTGTGGGGCCATAGCTG
AGCTCTTGGAGCCCAGTGACTATGACATCCCGCCAACCTCACATTTGTACTCGCTCAAACCCAA
GAGAGTAGGAGCTGGCTTCTCTAAAGGCCCCTGCCCATTCCAGACAGCCACAGAACTGTTGGGC
AAGTCTCAGACCGAGAAGCTGGCCCCAGAGGCTGCACTGGAGAGTGAACAGGAGCCCTCAGGCT
GGGTCTGTGATCCTCAAGATGGAGACAGGAGCAAGCCCTGCCTTGGGTACCAAGAGGAAGCTCC
TGGAAGCAGGACTAATTGTGGGGATCCCTCACCTGAGAAGAGGACAAAAGGCTCTTCCCAGGGC
AGTGCCAAGGCTAGGGCCAGCAAGAGACAGCAGCTCTTAGCCACAGCAGCCCGCAAGGACTCCC
AGAGTATCACCCGATTCCTCCGTCAGAGAACAGAATGCCCGCCACCCGCTGCTTCCGTCCCCAG
TTCAGAAGATGCCAGCCCCTGTGGGGATGTCCCAGGGAAGTGCACAGAAGAAGTTGGAGCCCAG
GGACATTTGGTGGCTGTATTTCAGACTGAGTGTCCCAGGGAGAGGCTAAGCACCTGCTCACTTG
AAGACCAGAGCCTCCCCAAAGGTCAGCCTAGCCCTCTAAAGGAAACCCAGGCGGAGAAGAGGCC
CAGACCACAGCAGGAAAGCCAAGAGAAGAGGGCTCAGAAGAGGCTTCGCCCCTCAACCAACTCT
TCCGCCTTGGCCAGTGACCCCAGCACCGAGAACAGAGTGGCTCGCGAACCTTGCCAGCTCTCAG
CTCCTGGCATCTCCCTGAAAGAGGCTGCAGACATTGTGGTCAGGACTTGTTCAAGGGCTTTGCC
CGCCACCTCTCACATTTGCTGGCTCAGAAGCTCTCTCCTGGAAGGAGTGTGAAGGAAGAGGCCC
AGAGCCTAATCAAGCAGTTCTTCCACAACCGTGCCCGGTGCGAGAGTGAAGCTGACTGGCATGG
CCTGTGTGGCCCACAGCGATGACTGAACAATGCCTGCGTCTCCCTCTTGCCCTCTGTGCCACAG
GCACCAGCTTTCTCAGGGTCTTTCTCTCCGTGAACAAACCTCACTGGAGGTCAGAAGTCAGCAC
ACCTTCCTATTTAAGACCCTCCTGGTCCTCTGACAGCCTGCTTTCCTGGCCGGCCTTCATGGCC
AGATCTCCAGATACGAAGGTCCAGATAATATGGCTGCTGCCAAAGGGGAGGTTGTGTATGTGTG
TGTGTCGGGGGACCAATGGTCCTCCTGTCTTGTAGCTAAGTTCTCTATCAGGGTGGGGCCCACT
CCAGTTCTCCACTGCCCTCTTCTATGAGATGTCGGCCTGTAGACCTTGTCCCAGCAGAGCTCAC
TGGGAGAGAAGCTCTGCAGCTCAGGAAGGCCAGGCCCAAGTGAGATATGCAAGAATAAAGTCCT
TGTGGAGACA

hide sequence

RefSeq Acc Id:

XM_039085674 ⟹ XP_038941602

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	101,625,477 - 101,664,037 (-)	NCBI
mRatBN7.2	10	101,126,544 - 101,165,739 (-)	NCBI

RefSeq Acc Id:

XM_039085675 ⟹ XP_038941603

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	101,625,477 - 101,634,193 (-)	NCBI
mRatBN7.2	10	101,126,544 - 101,136,536 (-)	NCBI

RefSeq Acc Id:

XM_039085676 ⟹ XP_038941604

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	101,642,001 - 101,664,037 (-)	NCBI
mRatBN7.2	10	101,141,627 - 101,165,739 (-)	NCBI

RefSeq Acc Id:

XR_005489766

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	101,627,986 - 101,664,037 (-)	NCBI
mRatBN7.2	10	101,129,047 - 101,165,739 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001099323	(Get FASTA)	NCBI Sequence Viewer
	XP_017452650	(Get FASTA)	NCBI Sequence Viewer
	XP_038941602	(Get FASTA)	NCBI Sequence Viewer
	XP_038941603	(Get FASTA)	NCBI Sequence Viewer
	XP_038941604	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	D4ACP5	(Get FASTA)	NCBI Sequence Viewer
	EDM06625	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000007246.4
	ENSRNOP00000096399.1
	ENSRNOP00065028525

RefSeq Acc Id:

NP_001099323 ⟸ NM_001105853

- UniProtKB:

D4ACP5 (UniProtKB/Swiss-Prot), A0A8I6ALQ3 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSARPFSTPFDRERRVRSTLKKVFGFDSFKTPLQESAIMAVVKGDKDVFVCMPTGAGKSLCYQL
PAVLAKGITIVVSPLIALIQDQVDHLLALKVQVSSLNSKLSVQERKELLSDLERDKPRTKLLYI
TPEMAASASFQPTLNSLLSRNLLSYLVVDEAHCVSQWGHDFRPDYLRLGALRSRLAHAPCVALT
ATATPQVQEDVFAALHLKQPVASFKTPCFRANLFYDVQFKELIPDVYGNLRDFCLKALGQKADN
GSSSGCGIVYCRTREACEQLAIELSSRGVNAKAYHAGLKASERTQVQNEWMEEKVPVIVATISF
GMGVDKANVRFVAHWNIAKSMAGYYQESGRAGRDGKPSWCRLYYSRNDRDQVSFLIRKELAKLQ
EKRGNKPSDKATLLAFDALVTFCEEVGCRHAAIAKYFGDAPPACAKGCDCCQSPAAIRKKLDAL
EHSSSWGKTCIGPSQGDGFDPELYEGGRRGYGGFSRYDEGSGGSGDEGRDEAHKREWNLFYQRQ
MSLRKGKEAKPEEFTPPGEDCPLRDASSRKIPKLTVKAREHCLRLLEEALNSNHQAAGSTHGAD
LQAKAVELEHETFRSAKMVNLYKASVLKKVAEIHKASKDGQLYDMESSTKSCGAIAELLEPSDY
DIPPTSHLYSLKPKRVGAGFSKGPCPFQTATELLGKSQTEKLAPEAALESEQEPSGWVCDPQDG
DRSKPCLGYQEEAPGSRTNCGDPSPEKRTKGSSQGSAKARASKRQQLLATAARKDSQSITRFLR
QRTECPPPAASVPSSEDASPCGDVPGKCTEEVGAQGHLVAVFQTECPRERLSTCSLEDQSLPKG
QPSPLKETQAEKRPRPQQESQEKRAQKRLRPSTNSSALASDPSTENRVAREPCQLSAPGISLKE
AADIVVRYLTPFYKEGRFISKDLFKGFARHLSHLLAQKLSPGRSVKEEAQSLIKQFFHNRARCE
SEADWHGLCGPQR

hide sequence

RefSeq Acc Id:	XP_017452650 ⟸ XM_017597161
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6ALQ3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSARPFSTPFDRERRVRSTLKKVFGFDSFKTPLQESAIMAVVKGDKDVFVCMPTGAGKSLCYQL PAVLAKGITIVVSPLIALIQDQVDHLLALKVQVSSLNSKLSVQERKELLSDLERDKPRTKLLYI TPEMAASASFQPTLNSLLSRNLLSYLVVDEAHCVSQWGHDFRPDYLRLGALRSRLAHAPCVALT ATATPQVQEDVFAALHLKQPVASFKTPCFRANLFYDVQFKELIPDVYGNLRDFCLKALGQKADN GSSSGCGIVYCRTREACEQLAIELSSRGVNAKAYHAGLKASERTQVQNEWMEEKVPVIVATISF GMGVDKANVRFVAHWNIAKSMAGYYQESGRAGRDGKPSWCRLYYSRNDRDQVSFLIRKELAKLQ EKRGNKPSDKATLLAFDALVTFCEEVGCRHAAIAKYFGDAPPACAKGCDCCQSPAAIRKKLDAL EHSSSWGKTCIGPSQGDGFDPELYEGGRRGYGGFSRYDEGSGGSGDEGRDEAHKREWNLFYQRQ MSLRKGKEAKPEEFTPPGEDCPLRDASSRKIPKLTVKAREHCLRLLEEALNSNHQAAGSTHGAD LQAKAVELEHETFRSAKMVNLYKASVLKKVAEIHKASKDGQLYDMESSTKSCGAIAELLEPSDY DIPPTSHLYSLKPKRVGAGFSKGPCPFQTATELLGKSQTEKLAPEAALESEQEPSGWVCDPQDG DRSKPCLGYQEEAPGSRTNCGDPSPEKRTKGSSQGSAKARASKRQQLLATAARKDSQSITRFLR QRTECPPPAASVPSSEDASPCGDVPGKCTEEVGAQGHLVAVFQTECPRERLSTCSLEDQSLPKG QPSPLKETQAEKRPRPQQESQEKRAQKRLRPSTNSSALASDPSTENRVAREPCQLSAPGISLKE AADIVVRTCSRALPATSHICWLRSSLLEGV hide sequence

Ensembl Acc Id:

ENSRNOP00000007246 ⟸ ENSRNOT00000007246

RefSeq Acc Id:	XP_038941602 ⟸ XM_039085674
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6ALQ3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038941603 ⟸ XM_039085675
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038941604 ⟸ XM_039085676
- Peptide Label:	isoform X4

Ensembl Acc Id:

ENSRNOP00000096399 ⟸ ENSRNOT00000104127

Protein Domains

Helicase ATP-binding Helicase C-terminal

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D4ACP5-F1-model_v2	AlphaFold	D4ACP5	1-973	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13697897

Promoter ID:

EPDNEW_R8421

Type:

multiple initiation site

Name:

Recql5_1

Description:

RecQ like helicase 5

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	10	104,482,858 - 104,482,918	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1310823	AgrOrtholog
BioCyc Gene	G2FUF-22644	BioCyc
Ensembl Genes	ENSRNOG00000005107	Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ENSRNOG00065020860	UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000007246.6	UniProtKB/Swiss-Prot
	ENSRNOT00000104127.1	UniProtKB/TrEMBL
	ENSRNOT00065035417	UniProtKB/Swiss-Prot
Gene3D-CATH	3.40.50.300	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	6.10.250.2460	UniProtKB/Swiss-Prot
	6.10.250.3140	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	DEAD/DEAH_box_helicase_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	DNA/RNA_helicase_DEAH_CS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	DNA_helicase_ATP-dep_RecQ	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Helicase_ATP-bd	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Helicase_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	RECQ5	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	RecQ_Zn-bd	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SRI	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:287834	UniProtKB/Swiss-Prot
NCBI Gene	287834	ENTREZGENE
PANTHER	ATP-DEPENDENT DNA HELICASE Q5	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	DNA HELICASE RECQ FAMILY MEMBER	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	DEAD	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Helicase_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	RecQ5	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	RecQ_Zn_bind	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SRI	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Recql5	PhenoGen
PROSITE	DEAH_ATP_HELICASE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	HELICASE_ATP_BIND_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	HELICASE_CTER	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000005107	RatGTEx
	ENSRNOG00065020860	RatGTEx
SMART	DEXDc	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	HELICc	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF52540	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8I6ALQ3	ENTREZGENE, UniProtKB/TrEMBL
	D4ACP5	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-02-11	Recql5	RecQ like helicase 5	Recql5	RecQ helicase-like 5	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2015-08-13	Recql5	RecQ helicase-like 5	Recql5	RecQ protein-like 5	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Recql5	RecQ protein-like 5	Recql5_predicted	RecQ protein-like 5 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Recql5_predicted	RecQ protein-like 5 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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