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Gene: Nrros (negative regulator of reactive oxygen species) Rattus norvegicus

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Symbol:

Nrros

Name:

negative regulator of reactive oxygen species

RGD ID:

1310771

Description:

Predicted to enable receptor ligand inhibitor activity and transforming growth factor beta binding activity. Predicted to be involved in several processes, including microglia development; sequestering of TGFbeta in extracellular matrix; and transforming growth factor beta receptor signaling pathway. Predicted to be located in cell surface and endoplasmic reticulum. Predicted to be active in extracellular space. Orthologous to human NRROS (negative regulator of reactive oxygen species); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4-amino-2,6-dinitrotoluene; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

Garpl1; leucine rich repeat containing 33; leucine-rich repeat-containing protein 33; leucine-rich repeat-containing protein 33^; LOC303875; Lrrc33; MGC108848; RGD1310771; similar to GARP protein precursor (Garpin) (Glycoprotein A repetitions predominant); transforming growth factor beta activator LRRC33

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	NRROS (negative regulator of reactive oxygen species)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, PhylomeDB
Mus musculus (house mouse):	Nrros (negative regulator of reactive oxygen species)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Nrros (negative regulator of reactive oxygen species)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	NRROS (negative regulator of reactive oxygen species)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	NRROS (negative regulator of reactive oxygen species)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Nrros (negative regulator of reactive oxygen species)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	NRROS (negative regulator of reactive oxygen species)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	NRROS (negative regulator of reactive oxygen species)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Nrros (negative regulator of reactive oxygen species)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Nrros (negative regulator of reactive oxygen species)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Nrros (negative regulator of reactive oxygen species)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	NRROS (negative regulator of reactive oxygen species)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	nrros (negative regulator of reactive oxygen species)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	conv	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Drosophila melanogaster (fruit fly):	cDIP	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Drosophila melanogaster (fruit fly):	CG42346	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Drosophila melanogaster (fruit fly):	alrm	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Drosophila melanogaster (fruit fly):	CG4950	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Drosophila melanogaster (fruit fly):	CG7800	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Drosophila melanogaster (fruit fly):	Gp150	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	nrros	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	nrros	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	11	82,133,608 - 82,151,160 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	11	82,133,144 - 82,151,308 (+)	Ensembl				GRCr8
mRatBN7.2	11	68,628,641 - 68,646,152 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	68,628,712 - 68,646,142 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	11	77,465,760 - 77,483,195 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	11	70,123,216 - 70,140,811 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	11	69,154,869 - 69,172,305 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	11	71,872,728 - 71,889,897 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	71,872,830 - 71,889,887 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	11	74,956,672 - 74,973,823 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	11	70,449,116 - 70,466,412 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	11	68,051,440 - 68,068,647 (+)	NCBI		Celera
RGSC_v3.1	11	70,506,704 - 70,523,991 (+)	NCBI
Cytogenetic Map	11	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Experimental Liver Cirrhosis (ISO)

genetic disease (ISO)

SEIZURES, EARLY-ONSET, WITH NEURODEGENERATION AND BRAIN CALCIFICATIONS (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

3,4-methylenedioxymethamphetamine (ISO)

4,4'-sulfonyldiphenol (ISO)

4-amino-2,6-dinitrotoluene (EXP)

4-hydroxyphenyl retinamide (ISO)

5-aza-2'-deoxycytidine (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

alpha-Zearalanol (EXP)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

carbon nanotube (ISO)

chloroprene (ISO)

chlorpyrifos (ISO)

cisplatin (ISO)

Cuprizon (EXP)

deoxynivalenol (ISO)

Dibutyl phosphate (ISO)

dioxygen (ISO)

doxorubicin (ISO)

ethanol (ISO)

ethyl methanesulfonate (ISO)

glyphosate (ISO)

HC toxin (ISO)

lipopolysaccharide (ISO)

methyl methanesulfonate (ISO)

N-nitrosodimethylamine (EXP)

nickel atom (ISO)

panobinostat (ISO)

paracetamol (ISO)

paraquat (ISO)

perfluorooctanoic acid (EXP)

propanal (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

S-nitrosoglutathione (ISO)

sodium fluoride (ISO)

Soman (EXP)

tetrachloromethane (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

triptonide (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

immune response (IBA,IEA,ISO,ISS)

inflammatory response (IBA,IEA,ISO,ISS)

innate immune response (ISO,ISS)

microglia development (IEA,ISO,ISS)

sequestering of TGFbeta in extracellular matrix (IBA,IEA,ISO,ISS)

superoxide metabolic process (ISO,ISS)

transforming growth factor beta receptor signaling pathway (IBA,IEA,ISO)

Cellular Component

cell surface (IBA,IEA,ISO,ISS)

endoplasmic reticulum (IEA,ISO,ISS)

endoplasmic reticulum membrane (IEA)

extracellular region (IEA)

plasma membrane (IEA)

Molecular Function

growth factor binding (IEA)

protein binding (ISO)

receptor ligand inhibitor activity (IEA,ISO,ISS)

transforming growth factor beta binding (IBA,IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	GOA pipeline	RGD automated data pipeline
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:15489334	PMID:24739962	PMID:28459434	PMID:29909984

Genomics

Comparative Map Data

Nrros
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	11	82,133,608 - 82,151,160 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	11	82,133,144 - 82,151,308 (+)	Ensembl				GRCr8
mRatBN7.2	11	68,628,641 - 68,646,152 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	68,628,712 - 68,646,142 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	11	77,465,760 - 77,483,195 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	11	70,123,216 - 70,140,811 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	11	69,154,869 - 69,172,305 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	11	71,872,728 - 71,889,897 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	71,872,830 - 71,889,887 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	11	74,956,672 - 74,973,823 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	11	70,449,116 - 70,466,412 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	11	68,051,440 - 68,068,647 (+)	NCBI		Celera
RGSC_v3.1	11	70,506,704 - 70,523,991 (+)	NCBI
Cytogenetic Map	11	q22	NCBI

NRROS
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	196,639,694 - 196,662,004 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	196,639,694 - 196,662,004 (+)	Ensembl			hg38	GRCh38
GRCh37	3	196,366,565 - 196,388,875 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	197,851,053 - 197,873,272 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	3	194,948,253 - 194,970,470 (+)	NCBI		Celera
Cytogenetic Map	3	q29	NCBI
HuRef	3	193,663,748 - 193,685,954 (+)	NCBI		HuRef
CHM1_1	3	196,337,936 - 196,360,147 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	3	199,359,041 - 199,381,340 (+)	NCBI		T2T-CHM13v2.0

Nrros
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	16	31,961,603 - 31,984,412 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	16	31,961,603 - 31,984,412 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	16	32,142,785 - 32,165,594 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	16	32,142,785 - 32,165,594 (-)	Ensembl			mm10	GRCm38
MGSCv37	16	32,142,911 - 32,165,562 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	16	32,062,572 - 32,085,223 (-)	NCBI		MGSCv36	mm8
Celera	16	32,639,762 - 32,659,142 (-)	NCBI		Celera
Cytogenetic Map	16	B2	NCBI
cM Map	16	22.4	NCBI

Nrros
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955420	12,792,111 - 12,801,963 (+)	Ensembl
ChiLan1.0	NW_004955420	12,792,173 - 12,798,645 (+)	NCBI	ChiLan1.0	ChiLan1.0

NRROS
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	194,510,493 - 194,533,526 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	194,515,212 - 194,538,237 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	193,984,797 - 194,007,173 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	203,925,101 - 203,948,506 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	203,920,334 - 203,948,506 (+)	Ensembl			panPan2	panpan1.1

NRROS
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	33	29,682,182 - 29,699,469 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	33	29,692,371 - 29,767,771 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	33	29,699,502 - 29,723,146 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	33	29,919,288 - 29,942,927 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	33	29,919,307 - 29,942,787 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	33	29,696,615 - 29,720,261 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	33	29,751,932 - 29,775,642 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	33	30,374,170 - 30,397,856 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Nrros
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	124,634,255 - 124,663,044 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936784	1,222,042 - 1,250,565 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936784	1,222,381 - 1,250,501 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NRROS
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	133,470,645 - 133,496,223 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	13	133,470,641 - 133,496,218 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	143,119,166 - 143,143,926 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NRROS
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	15	90,558,837 - 90,580,291 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	15	90,558,770 - 90,579,175 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666041	64,347,551 - 64,369,085 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Nrros
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624730	61,735,134 - 61,742,541 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624730	61,717,592 - 61,742,374 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Nrros
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	4	16,962,925 - 16,980,214 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Nrros
74 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	127
Count of miRNA genes:	106
Interacting mature miRNAs:	112
Transcripts:	ENSRNOT00000050364
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300147	Bp187	Blood pressure QTL 187	3.67		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	11	22524746	82951192	Rat
70208	Niddm22	Non-insulin dependent diabetes mellitus QTL 22	3.61		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	11	73308487	96070872	Rat
724554	Iddm17	Insulin dependent diabetes mellitus QTL 17		0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	11	46443168	91443168	Rat
1581565	Pur10	Proteinuria QTL 10		0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	11	58272363	96350770	Rat
4889859	Pur28	Proteinuria QTL 28	19.5	0.001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	11	58928336	99753367	Rat
10755497	Bp388	Blood pressure QTL 388	2.76		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	11	32943067	89836615	Rat
1549848	Bvd6	Brain ventricular dilatation QTL 6	3.1	0.0001	brain ventricle morphology trait (VT:0000822)	hydrocephalus severity score (CMO:0001881)	11	79618519	99753367	Rat
10058954	Gmadr7	Adrenal mass QTL 7	2.49	0.0049	adrenal gland mass (VT:0010420)	both adrenal glands wet weight to body weight ratio (CMO:0002411)	11	73850894	99753367	Rat
2298551	Neuinf10	Neuroinflammation QTL 10	3.7		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	11	58931822	92356038	Rat
1300135	Rf19	Renal function QTL 19	3.38		blood creatinine amount (VT:0005328)	creatinine clearance (CMO:0000765)	11	54415391	96071021	Rat
2312566	Glom20	Glomerulus QTL 20	3.6	0.001	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	11	57754837	96071021	Rat
724563	Uae10	Urinary albumin excretion QTL 10	6		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	11	20193549	96351019	Rat
724561	Plsm4	Polydactyly-luxate syndrome (PLS) morphotypes QTL 4		0.0003	forelimb integrity trait (VT:0010562)	front foot phalanges count (CMO:0001947)	11	67962184	99753367	Rat
631506	Bp104	Blood pressure QTL 104	2.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	11	73308315	99753367	Rat
4889521	Gluco62	Glucose level QTL 62	2.82	0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	11	68599321	96497754	Rat
7411658	Foco27	Food consumption QTL 27	16.2	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	11	69855943	99753367	Rat
1581572	Uae35	Urinary albumin excretion QTL 35		0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	11	58272363	96350770	Rat
1300110	Stl7	Serum triglyceride level QTL 7	4.64		blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	11	51071021	96071021	Rat

Markers in Region

BE097868

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	11	68,629,587 - 68,629,738 (+)	MAPPER	mRatBN7.2
Rnor_6.0	11	71,873,706 - 71,873,856	NCBI	Rnor6.0
Rnor_5.0	11	74,957,632 - 74,957,782	UniSTS	Rnor5.0
RGSC_v3.4	11	70,449,992 - 70,450,142	UniSTS	RGSC3.4
Celera	11	68,052,316 - 68,052,466	UniSTS
RH 3.4 Map	11	375.53	UniSTS
Cytogenetic Map	11	q22	UniSTS

RH144042

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	11	68,645,862 - 68,646,045 (+)	MAPPER	mRatBN7.2
Rnor_6.0	11	71,889,608 - 71,889,790	NCBI	Rnor6.0
Rnor_5.0	11	74,973,534 - 74,973,716	UniSTS	Rnor5.0
RGSC_v3.4	11	70,466,123 - 70,466,305	UniSTS	RGSC3.4
Celera	11	68,068,358 - 68,068,540	UniSTS
RH 3.4 Map	11	404.6	UniSTS
Cytogenetic Map	11	q22	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	163	91	90	59	92	59	6	356	192	11	142	81	92	31	16	16

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001024995	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006248448	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC091190	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473967	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000011	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000050364 ⟹ ENSRNOP00000048680

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	11	82,144,228 - 82,151,150 (+)	Ensembl
mRatBN7.2 Ensembl	11	68,628,712 - 68,646,142 (+)	Ensembl
Rnor_6.0 Ensembl	11	71,872,830 - 71,889,887 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000095949 ⟹ ENSRNOP00000077154

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	11	82,137,042 - 82,151,150 (+)	Ensembl
mRatBN7.2 Ensembl	11	68,632,029 - 68,646,142 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000138184 ⟹ ENSRNOP00000109205

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	11	82,133,144 - 82,151,150 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000139869 ⟹ ENSRNOP00000109740

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	11	82,136,446 - 82,151,308 (+)	Ensembl

RefSeq Acc Id:

NM_001024995 ⟹ NP_001020166

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	82,133,725 - 82,151,160 (+)	NCBI
mRatBN7.2	11	68,628,712 - 68,646,152 (+)	NCBI
Rnor_6.0	11	71,872,830 - 71,889,897 (+)	NCBI
Rnor_5.0	11	74,956,672 - 74,973,823 (+)	NCBI
RGSC_v3.4	11	70,449,116 - 70,466,412 (+)	RGD
Celera	11	68,051,440 - 68,068,647 (+)	RGD

Sequence:

show sequence

GCAGCGCGGCAGCGGCAACTGCTGTCCAGGAGGCCCGGGCCCTGGAGACGATGCGCCCCGCGGA
GCCGCCTGGGCCTGCGGGAGCAGTGAGTATTTCGTGCGTGGGTTCACCGCCGAGCATCGCGAGC
ATCGCTGGGGTACTAGAGAGCTGCACCTGAGATGGAGTTCCTGCCCCTGTGGCTTTGCCTGGGT
TTTCACTTCTTGATTGTGGAATGGAGGAGCGGACGTGGGACAGCTACTGCAGCTTCCCAAGGAG
GCTGCAAGGTGGTCGACCGAGTCGCTGACTGCCGCAGTCTGAACCTCGCTTCAGTACCCAGCGG
CCTCCCGGCCCATTCCCGGATGCTCGTTCTGGATGCCAACCCTCTCAGGGTTCTGTGGAATCAT
TCCCTCCAGGCCTACCCACGCCTGGAGGACCTCAGCCTGCACAGCTGTCACCTGGACCGTATCA
GCCACTGGGCCTTCCATGAGCAAGGCCACTTACAAAACCTGGTTCTGGCAGACAACCGCCTCTC
CGAGAACTACAAGGAGTCGGCCACAGCTCTCCACACCCTGCTGCGACTTCGAAGACTGGACTTG
TCTGGAAACTCCCTGACAGAAGACATGGCAGCTCTCATGCTTCAGAACCTCTCCTCATTGGAGG
TCGTGTCCTTGGCAAGAAATACCCTCATGAGGCTCGACGACTCTGTCTTCGAGGGCCTGGAGCG
CCTCGTGGAGCTGGATTTGCAGAGAAACTACATCTTTGAGATCGAGGGCGGTGCGTTTGACGGC
TTGACTGAGCTGAGGCGTCTCAACCTTGCCTACAACAACCTCCCCTGCATCGTGGACTTCAGCC
TCACACAGTTGCGGTTCCTCAACGTCAGTTACAACATCCTGGAGTGGTTCCTGGCAGCCAGGGA
AGAGGCGGCCTTCGAACTGGAGATACTGGACCTGTCTCACAACCAGCTGCTCTTCTTCCCGCTC
CTGCCTCAGTGTGGCAAGCTGCACACGCTCCTGCTGCAGGACAACAGCATGGGCTTCTACAGGG
AGCTTTACAACACCTCCTCCCCACAGGAGATGGTGGCCCAGTTCCTTCTCGTGGATGGTAATGT
TACTAATATCACAACCGTCAGCCTCTGGGAGGAGTTCTCCTCCAGCGACCTGTCAGCGCTTCGC
TTCCTGGACATGAGCCAAAACCAGTTGCGGCACCTGCCGGATGGTTTCCTGAAGAAAACGCCTT
CCCTTTCCCACCTGAACCTCAACCAAAATTGCCTGACGAAGCTCCACATTCGGGAGCACGAGCC
GCCGGGAGCGCTCACTGAGCTGGATCTGAGCCGCAACCAGCTGGCAGAACTGCACTTGGCCCCT
GGGCTCACTGGTTCCCTCAAGAACCTCAGAGTGTTCAACCTGAGCTCCAACCAGCTCCTGGGAG
TCCCCACTGGCCTTTTCCACAGCGCCAGCAGCATCACTACACTTGACATGAGCCACAATCAGAT
CTCACTTTGTCCCCAGACAGTGCCCTTAGACTGGGAGGAGCCCTCCAGTTGTGTGGATTTCAGA
AACATGGCCTCTTTGAGGAGCCTTTCTCTGGATGGCTGTGGGCTGAAGGCATTACAAGACTGCC
CATTCCAGGGGACCTCCCTCACTCATTTAGATCTGTCTAGCAACTGGGGGATTCTGAATGGGAG
CGTCAGCCCTCTCTCGGCTGTTGCCCCTACATTACAGGTCCTGTCTCTCAGGAACGTGGGCCTT
GGTTCTGGCGCTGCAGAGATGGACTTCTCTGGGTTTGGGAATCTGAGGGAGTTGGATCTGTCAG
GAAATTCCCTGACCAGCTTCCCCAAGTTCAAGGGCAGTTCGGCCCTGCAGACTCTCGACCTCCG
CAGAAACTCTCTCACAGCCCTACCTCAGAGGGTTGTGTCGGAGCAGCCTCTGAGGGGTCTGCAG
ACCATCTACCTCAGCCAGAACCCTTATGACTGCTGTGGGGTGGAGGGATGGGGGGCCCTGCAGC
ACTTCAAGACTATTGCGGACCTGTCCATGGTCACTTGCAACCTCTCTTCCAAGATCATTCGTGT
GGTAGAGCTGCCAGAGGGCATACCTCAGGACTGTAAGTGGGGGCAGGTGGACACTGGTCTATTC
TACCTCGTGCTCATTCTGCCCAGCTGCCTCACCCTGCTGGTGGCCAGCACCGTCATCTTCCTCA
CTTTTAAGAAGCCTTTGCTTCAGGTCATCAAGAGCCGCTGTCACTGGTCCTCCATATACTGACC
CGGGTGCCAAGGTTAGAGACTTGGTTTGTCTCTCGAGGATGCGTCTCTCCACTGGGTCTTCACT
TGTTCAGGGGTCAAGTGTGGTGCGTTGAAGGTCAAACTAAAATTTGAATGAGTTCCATCTGCAG
TCCCATTAACTTCTCTCGTCCTTGTGATTTATCCTCATTGTCCTGGTGAAATATTTATTAAATG
ACATTCTGTGAGAATAAAGGGTGCGTCTTATAAATATTTTAAAAATCAAAAAAAAAAAAAAAAA
AAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006248448 ⟹ XP_006248510

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	82,133,608 - 82,151,160 (+)	NCBI
mRatBN7.2	11	68,628,641 - 68,646,152 (+)	NCBI
Rnor_6.0	11	71,872,728 - 71,889,897 (+)	NCBI
Rnor_5.0	11	74,956,672 - 74,973,823 (+)	NCBI

Sequence:

show sequence

GCTGAGTGCTGAGTCGCTGAGAGGCGAGGTCTCCATGTGACTTCAGTTTCCGTCCGTTCCTTCC
GCAAGTGCTAAAATAATCTGATGCCCCAGAGCGAGTAGGCAGCGCGGCAGCGGCAACTGCTGTC
CAGGAGGCCCGGGCCCTGGAGACGATGCGCCCCGCGGAGCCGCCTGGGCCTGCGGGAGCAAGCT
GCACCTGAGATGGAGTTCCTGCCCCTGTGGCTTTGCCTGGGTTTTCACTTCTTGATTGTGGAAT
GGAGGAGCGGACGTGGGACAGCTACTGCAGCTTCCCAAGGAGGCTGCAAGGTGGTCGACCGAGT
CGCTGACTGCCGCAGTCTGAACCTCGCTTCAGTACCCAGCGGCCTCCCGGCCCATTCCCGGATG
CTCGTTCTGGATGCCAACCCTCTCAGGGTTCTGTGGAATCATTCCCTCCAGGCCTACCCACGCC
TGGAGGACCTCAGCCTGCACAGCTGTCACCTGGACCGTATCAGCCACTGGGCCTTCCATGAGCA
AGGCCACTTACAAAACCTGGTTCTGGCAGACAACCGCCTCTCCGAGAACTACAAGGAGTCGGCC
ACAGCTCTCCACACCCTGCTGCGACTTCGAAGACTGGACTTGTCTGGAAACTCCCTGACAGAAG
ACATGGCAGCTCTCATGCTTCAGAACCTCTCCTCATTGGAGGTCGTGTCCTTGGCAAGAAATAC
CCTCATGAGGCTCGACGACTCTGTCTTCGAGGGCCTGGAGCGCCTCGTGGAGCTGGATTTGCAG
AGAAACTACATCTTTGAGATCGAGGGCGGTGCGTTTGACGGCTTGACTGAGCTGAGGCGTCTCA
ACCTTGCCTACAACAACCTCCCCTGCATCGTGGACTTCAGCCTCACACAGTTGCGGTTCCTCAA
CGTCAGTTACAACATCCTGGAGTGGTTCCTGGCAGCCAGGGAAGAGGCGGCCTTCGAACTGGAG
ATACTGGACCTGTCTCACAACCAGCTGCTCTTCTTCCCGCTCCTGCCTCAGTGTGGCAAGCTGC
ACACGCTCCTGCTGCAGGACAACAGCATGGGCTTCTACAGGGAGCTTTACAACACCTCCTCCCC
ACAGGAGATGGTGGCCCAGTTCCTTCTCGTGGATGGTAATGTTACTAATATCACAACCGTCAGC
CTCTGGGAGGAGTTCTCCTCCAGCGACCTGTCAGCGCTTCGCTTCCTGGACATGAGCCAAAACC
AGTTGCGGCACCTGCCGGATGGTTTCCTGAAGAAAACGCCTTCCCTTTCCCACCTGAACCTCAA
CCAAAATTGCCTGACGAAGCTCCACATTCGGGAGCACGAGCCGCCGGGAGCGCTCACTGAGCTG
GATCTGAGCCGCAACCAGCTGGCAGAACTGCACTTGGCCCCTGGGCTCACTGGTTCCCTCAAGA
ACCTCAGAGTGTTCAACCTGAGCTCCAACCAGCTCCTGGGAGTCCCCACTGGCCTTTTCCACAG
CGCCAGCAGCATCACTACACTTGACATGAGCCACAATCAGATCTCACTTTGTCCCCAGACAGTG
CCCTTAGACTGGGAGGAGCCCTCCAGTTGTGTGGATTTCAGAAACATGGCCTCTTTGAGGAGCC
TTTCTCTGGATGGCTGTGGGCTGAAGGCATTACAAGACTGCCCATTCCAGGGGACCTCCCTCAC
TCATTTAGATCTGTCTAGCAACTGGGGGATTCTGAATGGGAGCGTCAGCCCTCTCTCGGCTGTT
GCCCCTACATTACAGGTCCTGTCTCTCAGGAACGTGGGCCTTGGTTCTGGCGCTGCAGAGATGG
ACTTCTCTGGGTTTGGGAATCTGAGGGAGTTGGATCTGTCAGGAAATTCCCTGACCAGCTTCCC
CAAGTTCAAGGGCAGTTCGGCCCTGCAGACTCTCGACCTCCGCAGAAACTCTCTCACAGCCCTA
CCTCAGAGGGTTGTGTCGGAGCAGCCTCTGAGGGGTCTGCAGACCATCTACCTCAGCCAGAACC
CTTATGACTGCTGTGGGGTGGAGGGATGGGGGGCCCTGCAGCACTTCAAGACTATTGCGGACCT
GTCCATGGTCACTTGCAACCTCTCTTCCAAGATCATTCGTGTGGTAGAGCTGCCAGAGGGCATA
CCTCAGGACTGTAAGTGGGGGCAGGTGGACACTGGTCTATTCTACCTCGTGCTCATTCTGCCCA
GCTGCCTCACCCTGCTGGTGGCCAGCACCGTCATCTTCCTCACTTTTAAGAAGCCTTTGCTTCA
GGTCATCAAGAGCCGCTGTCACTGGTCCTCCATATACTGACCCGGGTGCCAAGGTTAGAGACTT
GGTTTGTCTCTCGAGGATGCGTCTCTCCACTGGGTCTTCACTTGTTCAGGGGTCAAGTGTGGTG
CGTTGAAGGTCAAACTAAAATTTGAATGAGTTCCATCTGCAGTCCCATTAACTTCTCTCGTCCT
TGTGATTTATCCTCATTGTCCTGGTGAAATATTTATTAAATGACATTCTGTGAGAATAAAGGGT
GCGTCTTATAAATATTTTAAAAATCAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001020166	(Get FASTA)	NCBI Sequence Viewer
	XP_006248510	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH91190	(Get FASTA)	NCBI Sequence Viewer
	EDM11434	(Get FASTA)	NCBI Sequence Viewer
	EDM11435	(Get FASTA)	NCBI Sequence Viewer
	EDM11436	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000048680.3
	ENSRNOP00000109205
GenBank Protein	Q5BK65	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_001020166 ⟸ NM_001024995
- Peptide Label:	precursor
- UniProtKB:	Q5BK65 (UniProtKB/Swiss-Prot), A6IRT2 (UniProtKB/TrEMBL), A0A8I5Y5F1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MEFLPLWLCLGFHFLIVEWRSGRGTATAASQGGCKVVDRVADCRSLNLASVPSGLPAHSRMLVL DANPLRVLWNHSLQAYPRLEDLSLHSCHLDRISHWAFHEQGHLQNLVLADNRLSENYKESATAL HTLLRLRRLDLSGNSLTEDMAALMLQNLSSLEVVSLARNTLMRLDDSVFEGLERLVELDLQRNY IFEIEGGAFDGLTELRRLNLAYNNLPCIVDFSLTQLRFLNVSYNILEWFLAAREEAAFELEILD LSHNQLLFFPLLPQCGKLHTLLLQDNSMGFYRELYNTSSPQEMVAQFLLVDGNVTNITTVSLWE EFSSSDLSALRFLDMSQNQLRHLPDGFLKKTPSLSHLNLNQNCLTKLHIREHEPPGALTELDLS RNQLAELHLAPGLTGSLKNLRVFNLSSNQLLGVPTGLFHSASSITTLDMSHNQISLCPQTVPLD WEEPSSCVDFRNMASLRSLSLDGCGLKALQDCPFQGTSLTHLDLSSNWGILNGSVSPLSAVAPT LQVLSLRNVGLGSGAAEMDFSGFGNLRELDLSGNSLTSFPKFKGSSALQTLDLRRNSLTALPQR VVSEQPLRGLQTIYLSQNPYDCCGVEGWGALQHFKTIADLSMVTCNLSSKIIRVVELPEGIPQD CKWGQVDTGLFYLVLILPSCLTLLVASTVIFLTFKKPLLQVIKSRCHWSSIY hide sequence

RefSeq Acc Id:	XP_006248510 ⟸ XM_006248448
- Peptide Label:	isoform X1
- UniProtKB:	Q5BK65 (UniProtKB/Swiss-Prot), A6IRT2 (UniProtKB/TrEMBL), A0A8I5Y5F1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MEFLPLWLCLGFHFLIVEWRSGRGTATAASQGGCKVVDRVADCRSLNLASVPSGLPAHSRMLVL DANPLRVLWNHSLQAYPRLEDLSLHSCHLDRISHWAFHEQGHLQNLVLADNRLSENYKESATAL HTLLRLRRLDLSGNSLTEDMAALMLQNLSSLEVVSLARNTLMRLDDSVFEGLERLVELDLQRNY IFEIEGGAFDGLTELRRLNLAYNNLPCIVDFSLTQLRFLNVSYNILEWFLAAREEAAFELEILD LSHNQLLFFPLLPQCGKLHTLLLQDNSMGFYRELYNTSSPQEMVAQFLLVDGNVTNITTVSLWE EFSSSDLSALRFLDMSQNQLRHLPDGFLKKTPSLSHLNLNQNCLTKLHIREHEPPGALTELDLS RNQLAELHLAPGLTGSLKNLRVFNLSSNQLLGVPTGLFHSASSITTLDMSHNQISLCPQTVPLD WEEPSSCVDFRNMASLRSLSLDGCGLKALQDCPFQGTSLTHLDLSSNWGILNGSVSPLSAVAPT LQVLSLRNVGLGSGAAEMDFSGFGNLRELDLSGNSLTSFPKFKGSSALQTLDLRRNSLTALPQR VVSEQPLRGLQTIYLSQNPYDCCGVEGWGALQHFKTIADLSMVTCNLSSKIIRVVELPEGIPQD CKWGQVDTGLFYLVLILPSCLTLLVASTVIFLTFKKPLLQVIKSRCHWSSIY hide sequence

Ensembl Acc Id:

ENSRNOP00000048680 ⟸ ENSRNOT00000050364

Ensembl Acc Id:

ENSRNOP00000077154 ⟸ ENSRNOT00000095949

Ensembl Acc Id:

ENSRNOP00000109740 ⟸ ENSRNOT00000139869

Ensembl Acc Id:

ENSRNOP00000109205 ⟸ ENSRNOT00000138184

Protein Domains

LRRCT LRRNT

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5BK65-F1-model_v2	AlphaFold	Q5BK65	1-692	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13698214

Promoter ID:

EPDNEW_R8739

Type:

multiple initiation site

Name:

Nrros_1

Description:

negative regulator of reactive oxygen species

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	11	71,872,819 - 71,872,879	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1310771	AgrOrtholog
BioCyc Gene	G2FUF-21082	BioCyc
Ensembl Genes	ENSRNOG00000001752	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000050364.4	UniProtKB/Swiss-Prot
	ENSRNOT00000138184	ENTREZGENE
Gene3D-CATH	3.80.10.10	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7367889	IMAGE-MGC_LOAD
InterPro	Leu-rich_rpt	UniProtKB/Swiss-Prot
	Leu-rich_rpt_typical-subtyp	UniProtKB/Swiss-Prot
	LRR_dom_sf	UniProtKB/Swiss-Prot
	SLRP	UniProtKB/Swiss-Prot
KEGG Report	rno:303875	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:108848	IMAGE-MGC_LOAD
NCBI Gene	303875	ENTREZGENE
PANTHER	AGAP008170-PA	UniProtKB/Swiss-Prot
	INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN COMPLEX ACID LABILE SUBUNIT	UniProtKB/Swiss-Prot
Pfam	LRR_8	UniProtKB/Swiss-Prot
PhenoGen	Nrros	PhenoGen
PRINTS	LEURICHRPT	UniProtKB/Swiss-Prot
PROSITE	LRR	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000001752	RatGTEx
SMART	LRR_BAC	UniProtKB/Swiss-Prot
	LRR_TYP	UniProtKB/Swiss-Prot
Superfamily-SCOP	L domain-like	UniProtKB/Swiss-Prot
	RNI-like	UniProtKB/Swiss-Prot
UniProt	A0A8I5Y5F1	ENTREZGENE, UniProtKB/TrEMBL
	A0ABK0LWA8_RAT	UniProtKB/TrEMBL
	A6IRT2	ENTREZGENE, UniProtKB/TrEMBL
	LRC33_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2013-07-18	Nrros	negative regulator of reactive oxygen species	Lrrc33	leucine rich repeat containing 33	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-30	Lrrc33	leucine rich repeat containing 33	RGD1310771	similar to GARP protein precursor (Garpin) (Glycoprotein A repetitions predominant)	Symbol and Name updated	1299863	APPROVED
2005-12-06	RGD1310771	similar to GARP protein precursor (Garpin) (Glycoprotein A repetitions predominant)	RGD1310771_predicted	similar to GARP protein precursor (Garpin) (Glycoprotein A repetitions predominant) (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-20	RGD1310771_predicted	similar to GARP protein precursor (Garpin) (Glycoprotein A repetitions predominant) (predicted)	LOC303875_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC303875_predicted	similar to GARP protein precursor (Garpin) (Glycoprotein A repetitions predominant) (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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