Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Itprid2 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Itprid2 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ITPRID2 mRNA | CTD | PMID:22206623 | Itprid2 | Rat | 17beta-estradiol | decreases expression | ISO | Itprid2 (Mus musculus) | 6480464 | Estradiol results in decreased expression of ITPRID2 mRNA | CTD | PMID:39298647 | Itprid2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of ITPRID2 mRNA | CTD | PMID:22298810 | Itprid2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Itprid2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of ITPRID2 mRNA | CTD | PMID:21570461 | Itprid2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Itprid2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ITPRID2 mRNA | CTD | PMID:19770486|PMID:19933214|PMID:33956508 | Itprid2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | ITPRID2 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin affects the expression of ITPRID2 mRNA | CTD | PMID:22574217 | Itprid2 | Rat | 2,6-dimethoxyphenol | multiple interactions | ISO | ITPRID2 (Homo sapiens) | 6480464 | [pyrogallol 1,3-dimethyl ether co-treated with Furaldehyde] results in decreased expression of and affects the localization more ... | CTD | PMID:38598786 | Itprid2 | Rat | 2-palmitoylglycerol | increases expression | ISO | ITPRID2 (Homo sapiens) | 6480464 | 2-palmitoylglycerol results in increased expression of ITPRID2 mRNA | CTD | PMID:37199045 | Itprid2 | Rat | 4,4'-sulfonyldiphenol | decreases expression | ISO | Itprid2 (Mus musculus) | 6480464 | bisphenol S results in decreased expression of ITPRID2 mRNA | CTD | PMID:39298647 | Itprid2 | Rat | 4,4'-sulfonyldiphenol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of more ... | CTD | PMID:36041667 | Itprid2 | Rat | 4-hydroxyphenyl retinamide | increases expression | ISO | Itprid2 (Mus musculus) | 6480464 | Fenretinide results in increased expression of ITPRID2 mRNA | CTD | PMID:28973697 | Itprid2 | Rat | 5-azacytidine | increases expression | ISO | ITPRID2 (Homo sapiens) | 6480464 | Azacitidine results in increased expression of ITPRID2 mRNA | CTD | PMID:20823114 | Itprid2 | Rat | aflatoxin B1 | decreases methylation | ISO | ITPRID2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of ITPRID2 gene | CTD | PMID:27153756 | Itprid2 | Rat | all-trans-retinoic acid | increases expression | ISO | ITPRID2 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of ITPRID2 mRNA | CTD | PMID:21934132 | Itprid2 | Rat | aristolochic acid A | decreases expression | ISO | ITPRID2 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of ITPRID2 mRNA | CTD | PMID:33212167 | Itprid2 | Rat | arsane | multiple interactions | ISO | ITPRID2 (Homo sapiens) | 6480464 | [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of ITPRID2 more ... | CTD | PMID:39836092 | Itprid2 | Rat | arsenic atom | multiple interactions | ISO | ITPRID2 (Homo sapiens) | 6480464 | [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of ITPRID2 more ... | CTD | PMID:39836092 | Itprid2 | Rat | arsenite(3-) | multiple interactions | ISO | ITPRID2 (Homo sapiens) | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to ITPRID2 mRNA] | CTD | PMID:32406909 | Itprid2 | Rat | arsenous acid | increases expression | ISO | ITPRID2 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of ITPRID2 mRNA | CTD | PMID:20458559 | Itprid2 | Rat | benzo[a]pyrene diol epoxide I | increases expression | ISO | ITPRID2 (Homo sapiens) | 6480464 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of ITPRID2 mRNA | CTD | PMID:26238291 | Itprid2 | Rat | bis(2-ethylhexyl) phthalate | increases expression | ISO | ITPRID2 (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in increased expression of SSFA2 mRNA | CTD | PMID:31163220 | Itprid2 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of ITPRID2 mRNA | CTD | PMID:25181051 | Itprid2 | Rat | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of more ... | CTD | PMID:36041667 | Itprid2 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of ITPRID2 mRNA | CTD | PMID:34947998 | Itprid2 | Rat | bisphenol A | increases expression | ISO | Itprid2 (Mus musculus) | 6480464 | bisphenol A results in increased expression of ITPRID2 mRNA | CTD | PMID:33221593 | Itprid2 | Rat | bisphenol A | decreases expression | ISO | Itprid2 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of ITPRID2 mRNA | CTD | PMID:26063408 | Itprid2 | Rat | bisphenol A | decreases expression | ISO | ITPRID2 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of ITPRID2 mRNA | CTD | PMID:29275510 | Itprid2 | Rat | bisphenol F | increases expression | ISO | Itprid2 (Mus musculus) | 6480464 | bisphenol F results in increased expression of ITPRID2 mRNA | CTD | PMID:38685157 | Itprid2 | Rat | bisphenol F | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of more ... | CTD | PMID:36041667 | Itprid2 | Rat | cadmium atom | multiple interactions | ISO | ITPRID2 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ITPRID2 more ... | CTD | PMID:35301059 | Itprid2 | Rat | cadmium atom | multiple interactions | EXP | | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SSFA2 more ... | CTD | PMID:39012411 | Itprid2 | Rat | cadmium dichloride | multiple interactions | ISO | ITPRID2 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ITPRID2 more ... | CTD | PMID:35301059 | Itprid2 | Rat | cadmium dichloride | multiple interactions | EXP | | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SSFA2 more ... | CTD | PMID:39012411 | Itprid2 | Rat | caffeine | affects phosphorylation | ISO | ITPRID2 (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of ITPRID2 protein | CTD | PMID:35688186 | Itprid2 | Rat | coumarin | decreases phosphorylation | ISO | ITPRID2 (Homo sapiens) | 6480464 | coumarin results in decreased phosphorylation of ITPRID2 protein | CTD | PMID:35688186 | Itprid2 | Rat | diarsenic trioxide | increases expression | ISO | ITPRID2 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of ITPRID2 mRNA | CTD | PMID:20458559 | Itprid2 | Rat | Dibutyl phosphate | affects expression | ISO | ITPRID2 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of ITPRID2 mRNA | CTD | PMID:37042841 | Itprid2 | Rat | dibutyl phthalate | increases expression | EXP | | 6480464 | Dibutyl Phthalate results in increased expression of ITPRID2 mRNA | CTD | PMID:21266533 | Itprid2 | Rat | dorsomorphin | multiple interactions | ISO | ITPRID2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Itprid2 | Rat | ethanol | increases expression | ISO | Itprid2 (Mus musculus) | 6480464 | Ethanol results in increased expression of ITPRID2 mRNA | CTD | PMID:30319688 | Itprid2 | Rat | fenamidone | increases expression | ISO | Itprid2 (Mus musculus) | 6480464 | fenamidone results in increased expression of ITPRID2 mRNA | CTD | PMID:27029645 | Itprid2 | Rat | fenthion | increases expression | ISO | Itprid2 (Mus musculus) | 6480464 | Fenthion results in increased expression of ITPRID2 mRNA | CTD | PMID:34813904 | Itprid2 | Rat | folic acid | multiple interactions | ISO | Itprid2 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ITPRID2 mRNA | CTD | PMID:22206623 | Itprid2 | Rat | FR900359 | affects phosphorylation | ISO | ITPRID2 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of ITPRID2 protein | CTD | PMID:37730182 | Itprid2 | Rat | furfural | multiple interactions | ISO | ITPRID2 (Homo sapiens) | 6480464 | [pyrogallol 1,3-dimethyl ether co-treated with Furaldehyde] results in decreased expression of and affects the localization more ... | CTD | PMID:38598786 | Itprid2 | Rat | geldanamycin | increases expression | ISO | ITPRID2 (Homo sapiens) | 6480464 | geldanamycin results in increased expression of SSFA2 mRNA | CTD | PMID:26705709 | Itprid2 | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of ITPRID2 mRNA | CTD | PMID:22061828|PMID:33387578 | Itprid2 | Rat | hexadecanoic acid | decreases phosphorylation | ISO | ITPRID2 (Homo sapiens) | 6480464 | Palmitic Acid results in decreased phosphorylation of ITPRID2 protein | CTD | PMID:28073184 | Itprid2 | Rat | hydrogen peroxide | affects expression | ISO | ITPRID2 (Homo sapiens) | 6480464 | Hydrogen Peroxide affects the expression of ITPRID2 mRNA | CTD | PMID:20044591 | Itprid2 | Rat | ivermectin | decreases expression | ISO | ITPRID2 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of ITPRID2 protein | CTD | PMID:32959892 | Itprid2 | Rat | lead(0) | affects expression | ISO | ITPRID2 (Homo sapiens) | 6480464 | Lead affects the expression of ITPRID2 mRNA | CTD | PMID:28903495 | Itprid2 | Rat | leflunomide | increases expression | ISO | ITPRID2 (Homo sapiens) | 6480464 | leflunomide results in increased expression of ITPRID2 mRNA | CTD | PMID:28988120 | Itprid2 | Rat | menadione | affects expression | ISO | ITPRID2 (Homo sapiens) | 6480464 | Vitamin K 3 affects the expression of ITPRID2 mRNA | CTD | PMID:20044591 | Itprid2 | Rat | mercury dichloride | decreases expression | ISO | ITPRID2 (Homo sapiens) | 6480464 | Mercuric Chloride results in decreased expression of ITPRID2 mRNA | CTD | PMID:27188386 | Itprid2 | Rat | methamphetamine | increases expression | ISO | Itprid2 (Mus musculus) | 6480464 | Methamphetamine results in increased expression of ITPRID2 mRNA | CTD | PMID:26307267 | Itprid2 | Rat | nickel sulfate | increases expression | ISO | ITPRID2 (Homo sapiens) | 6480464 | nickel sulfate results in increased expression of ITPRID2 mRNA | CTD | PMID:22714537 | Itprid2 | Rat | p-chloromercuribenzoic acid | increases expression | ISO | ITPRID2 (Homo sapiens) | 6480464 | p-Chloromercuribenzoic Acid results in increased expression of ITPRID2 mRNA | CTD | PMID:27188386 | Itprid2 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of ITPRID2 mRNA | CTD | PMID:33387578 | Itprid2 | Rat | perfluorooctane-1-sulfonic acid | decreases expression | ISO | ITPRID2 (Homo sapiens) | 6480464 | perfluorooctane sulfonic acid results in decreased expression of ITPRID2 mRNA | CTD | PMID:27153767 | Itprid2 | Rat | phenylmercury acetate | increases expression | ISO | ITPRID2 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in increased expression of ITPRID2 mRNA | CTD | PMID:26272509 | Itprid2 | Rat | phenylmercury acetate | multiple interactions | ISO | ITPRID2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Itprid2 | Rat | SB 431542 | multiple interactions | ISO | ITPRID2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Itprid2 | Rat | silver atom | decreases expression | ISO | Itprid2 (Mus musculus) | 6480464 | Silver results in decreased expression of ITPRID2 mRNA | CTD | PMID:27131904 | Itprid2 | Rat | silver(0) | decreases expression | ISO | Itprid2 (Mus musculus) | 6480464 | Silver results in decreased expression of ITPRID2 mRNA | CTD | PMID:27131904 | Itprid2 | Rat | sodium arsenate | increases expression | ISO | Itprid2 (Mus musculus) | 6480464 | sodium arsenate results in increased expression of ITPRID2 mRNA | CTD | PMID:21795629 | Itprid2 | Rat | sodium arsenite | affects methylation | ISO | ITPRID2 (Homo sapiens) | 6480464 | sodium arsenite affects the methylation of ITPRID2 gene | CTD | PMID:28589171 | Itprid2 | Rat | sodium arsenite | multiple interactions | ISO | ITPRID2 (Homo sapiens) | 6480464 | [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of ITPRID2 more ... | CTD | PMID:39836092 | Itprid2 | Rat | sodium arsenite | increases expression | ISO | ITPRID2 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of ITPRID2 mRNA | CTD | PMID:38568856 | Itprid2 | Rat | sodium chloride | multiple interactions | ISO | ITPRID2 (Homo sapiens) | 6480464 | [Sodium Chloride co-treated with Furaldehyde] results in increased expression of and affects the localization of more ... | CTD | PMID:38598786 | Itprid2 | Rat | sunitinib | increases expression | ISO | ITPRID2 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of ITPRID2 mRNA | CTD | PMID:31533062 | Itprid2 | Rat | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of ITPRID2 mRNA | CTD | PMID:31150632 | Itprid2 | Rat | thimerosal | decreases expression | ISO | ITPRID2 (Homo sapiens) | 6480464 | Thimerosal results in decreased expression of ITPRID2 mRNA | CTD | PMID:27188386 | Itprid2 | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of ITPRID2 mRNA | CTD | PMID:34492290 | Itprid2 | Rat | torcetrapib | increases expression | ISO | ITPRID2 (Homo sapiens) | 6480464 | torcetrapib results in increased expression of ITPRID2 mRNA | CTD | PMID:23228038 | Itprid2 | Rat | trichostatin A | increases expression | ISO | ITPRID2 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of ITPRID2 mRNA | CTD | PMID:24935251|PMID:26272509 | Itprid2 | Rat | trichostatin A | multiple interactions | ISO | ITPRID2 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Itprid2 | Rat | triptonide | decreases expression | ISO | Itprid2 (Mus musculus) | 6480464 | triptonide results in decreased expression of ITPRID2 mRNA | CTD | PMID:33045310 | Itprid2 | Rat | urethane | increases expression | ISO | ITPRID2 (Homo sapiens) | 6480464 | Urethane results in increased expression of ITPRID2 mRNA | CTD | PMID:28818685 | Itprid2 | Rat | valproic acid | decreases methylation | ISO | ITPRID2 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of ITPRID2 gene | CTD | PMID:29154799 | Itprid2 | Rat | valproic acid | increases expression | ISO | Itprid2 (Mus musculus) | 6480464 | Valproic Acid results in increased expression of ITPRID2 mRNA | CTD | PMID:19136453|PMID:21427059 | Itprid2 | Rat | valproic acid | increases expression | ISO | ITPRID2 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of ITPRID2 mRNA | CTD | PMID:23179753|PMID:24383497|PMID:26272509|PMID:28001369 | Itprid2 | Rat | valproic acid | multiple interactions | ISO | ITPRID2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Itprid2 | Rat | vincristine | decreases expression | ISO | ITPRID2 (Homo sapiens) | 6480464 | Vincristine results in decreased expression of ITPRID2 mRNA | CTD | PMID:23649840 | Itprid2 | Rat | vorinostat | affects expression | ISO | ITPRID2 (Homo sapiens) | 6480464 | vorinostat affects the expression of ITPRID2 mRNA | CTD | PMID:27188386 | Itprid2 | Rat | zoledronic acid | decreases expression | ISO | ITPRID2 (Homo sapiens) | 6480464 | zoledronic acid results in decreased expression of ITPRID2 mRNA | CTD | PMID:24714768 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















