Gene:	Nfatc4 ( Rattus norvegicus ) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
Description:	acts as a transcription factor, may play a role in regulation of synaptic plasticity
Synonyms:	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 (predicted); nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4; Nfatc4; Nfatc4_predicted;
ArrayIDs:	1390573_a_at; 1392426_x_at; rc_AI011576_at;  (details...)
Gene Type:	protein-coding
Additional Data
Homologs
Homo sapiens: NFATC4     See the Human gene in context in:     UCSC     NCBI MapViewer
Mus musculus: Nfatc4     See the Mouse gene in context in:     UCSC     NCBI MapViewer
Comparative Map Data Species Symbol Map Name Chr. Position Rattus norvegicus Nfatc4 Rat Celera Assembly 15 28878559 - 28889391     RGSC genome assembly v3.4 15 33968034 - 33978838     Cytogenetic 15 p13     genome assembly 3.1 15 33985319 - 33994626 Mus musculus Nfatc4 Mouse genome assembly build 36.1 14 56443845 - 56452780 Homo sapiens NFATC4 human genome assembly 14 23907093 - 23918648     Human genome assembly build 36.2 14 23907094 - 23918650     Cytogenetic 14 q11.2   View comparative maps:      NCBI MapViewer
Genome
View:
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Annotation
Molecular Function	Gene Ontology transcription factor activity,  DNA binding (details...)
Biological Process	Gene Ontology heart development,  regulation of transcription, DNA-dependent,  cellular respiration ...  (details...)
Cellular Component	Gene Ontology nucleus,  cytoplasm,  cytosol (details...)
Disease	Ontology Hypertrophy, Right Ventricular,  Hypertrophy, Left Ventricular,  Cardiomyopathy, Congestive (details...)
Pathway	Ontology nuclear factor of activated T-cells signaling pathway,  calcineurin signaling pathway (details...)
External Links
Databases	DATABASE ID SOURCE SMART: IPT IPI PROSITE: REL_2 IPI UNIPARC: UPI0001B7A1A8 IPI UNIPARC: UPI00001816C1 IPI KEGG Report: rno:305897 ENTREZGENE HomoloGene Group ID: 3349 ENTREZGENE Germonline: 1310749 Pfam: TIG IPI Pfam: RHD IPI KEGG Pathway: 04662 ENTREZGENE KEGG Pathway: 04660 ENTREZGENE KEGG Pathway: 04370 ENTREZGENE KEGG Pathway: 04310 ENTREZGENE KEGG Pathway: 04360 ENTREZGENE KEGG Pathway: 04650 ENTREZGENE KEGG Pathway: 04010 ENTREZGENE InterPro: RHD. IPI InterPro: p53-like_TF_DNA-bd. IPI InterPro: NFAT_sbgrp. IPI InterPro: NFAT. IPI InterPro: IPT_TIG_rcpt. IPI InterPro: Ig_E-set. IPI InterPro: Ig-like_fold. IPI IPI: IPI00952040 IPI IPI: IPI00205206 IPI Ensembl Protein: ENSRNOP00000060314 IPI Ensembl Protein: ENSRNOP00000027789 IPI Gene3D-CATH: RHD IPI Gene3D-CATH: Ig-like_fold IPI Entrez Gene: Nfatc4 ENTREZGENE Ensembl Genes: ENSRNOG00000020482 IPI Superfamily-SCOP: P53_like_DNA_bnd IPI Superfamily-SCOP: Ig_E-set IPI PANTHER: NFAT IPI PRINTS: NUCFACTORATC. IPI
Sequences	Nucleotide: NM_001107264 Get FASTA Search GEO Profiles Nucleotide: CH474049 Get FASTA Search GEO Profiles Nucleotide: XM_240184 Get FASTA Search GEO Profiles Nucleotide: XM_001061815 Get FASTA Search GEO Profiles (View all 4 Nucleotide Accessions) Protein: EDM14287 Get FASTA Protein: NP_001100734 Get FASTA Protein: XP_240184 Get FASTA Protein: XP_001061815 Get FASTA (View all 4 Protein Accessions)
Clusters	UniGene: 23727
References
Curated References	7 references in RGD related to Nfatc4
Other References	9 other references at PubMed related to Nfatc4
Database Information
RGD ID	1310749
History	Date Current Symbol Current Name Previous Symbol Previous name Status Description Reference 06-DEC-05: Nfatc4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 Nfatc4_predicted nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 (predicted) APPROVED Symbol and Name updated 1559027 12-JAN-05: Nfatc4_predicted nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 (predicted) APPROVED Symbol and Name status set to approved 70820