Dact2 (dishevelled-binding antagonist of beta-catenin 2) - Rat Genome Database

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Gene: Dact2 (dishevelled-binding antagonist of beta-catenin 2) Rattus norvegicus
Analyze
Symbol: Dact2
Name: dishevelled-binding antagonist of beta-catenin 2
RGD ID: 1310742
Description: Predicted to enable several functions, including beta-catenin binding activity; delta-catenin binding activity; and protein kinase C binding activity. Predicted to be involved in several processes, including epithelial cell morphogenesis; inner medullary collecting duct development; and negative regulation of nodal signaling pathway. Predicted to act upstream of or within hematopoietic progenitor cell differentiation. Predicted to be active in cytoplasm. Orthologous to human DACT2 (dishevelled binding antagonist of beta catenin 2); PARTICIPATES IN transforming growth factor-beta Smad dependent signaling pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: dapper homolog 2; dapper homolog 2, antagonist of beta-catenin; dapper homolog 2, antagonist of beta-catenin (xenopus) ; dapper, antagonist of beta-catenin, homolog 2; dapper, antagonist of beta-catenin, homolog 2 (Xenopus laevis); LOC308212
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8163,854,182 - 63,864,153 (-)NCBIGRCr8
mRatBN7.2155,181,023 - 55,191,026 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl155,181,024 - 55,191,096 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx160,052,775 - 60,061,679 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0168,709,151 - 68,718,086 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0161,962,725 - 61,971,629 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0156,159,435 - 56,169,443 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl156,159,426 - 56,168,351 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0157,354,080 - 57,364,005 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4153,084,115 - 53,093,031 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1153,087,456 - 53,098,585 (-)NCBI
Celera151,399,334 - 51,408,533 (-)NCBICelera
Cytogenetic Map1q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (EXP)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (EXP,ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
bexarotene  (EXP)
bisphenol A  (EXP,ISO)
butanal  (ISO)
C60 fullerene  (EXP)
carbon nanotube  (ISO)
choline  (ISO)
chromium(6+)  (ISO)
ciguatoxin CTX1B  (ISO)
clofibrate  (EXP)
copper atom  (EXP)
copper(0)  (EXP)
diuron  (EXP)
endosulfan  (EXP)
ethanol  (ISO)
fenofibrate  (EXP)
flusilazole  (EXP)
folic acid  (ISO)
gemfibrozil  (EXP)
genistein  (ISO)
gentamycin  (EXP)
glycidol  (EXP)
hydralazine  (ISO)
indole-3-methanol  (EXP)
L-methionine  (ISO)
methapyrilene  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N-nitrosodiethylamine  (EXP)
orphenadrine  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
PCB138  (ISO)
perfluorooctanoic acid  (EXP)
phenobarbital  (EXP)
pirinixic acid  (EXP)
pregnenolone 16alpha-carbonitrile  (EXP)
propiconazole  (EXP)
resveratrol  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
tamoxifen  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (EXP)
tetraphene  (ISO)
triadimefon  (EXP)
trichloroethene  (EXP)
trimellitic anhydride  (ISO)
triphenyl phosphate  (EXP)
urethane  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:17197390   PMID:18614015   PMID:18716284   PMID:20685821   PMID:21718540   PMID:24029230   PMID:35818217  


Genomics

Comparative Map Data
Dact2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8163,854,182 - 63,864,153 (-)NCBIGRCr8
mRatBN7.2155,181,023 - 55,191,026 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl155,181,024 - 55,191,096 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx160,052,775 - 60,061,679 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0168,709,151 - 68,718,086 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0161,962,725 - 61,971,629 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0156,159,435 - 56,169,443 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl156,159,426 - 56,168,351 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0157,354,080 - 57,364,005 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4153,084,115 - 53,093,031 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1153,087,456 - 53,098,585 (-)NCBI
Celera151,399,334 - 51,408,533 (-)NCBICelera
Cytogenetic Map1q12NCBI
DACT2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386168,292,830 - 168,319,777 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6168,292,830 - 168,319,777 (-)EnsemblGRCh38hg38GRCh38
GRCh376168,693,510 - 168,720,457 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366168,450,433 - 168,463,251 (-)NCBINCBI36Build 36hg18NCBI36
Build 346168,526,141 - 168,538,958NCBI
Celera6169,426,389 - 169,438,204 (-)NCBICelera
Cytogenetic Map6q27NCBI
HuRef6166,135,772 - 166,147,168 (-)NCBIHuRef
CHM1_16168,970,293 - 168,981,504 (-)NCBICHM1_1
T2T-CHM13v2.06169,636,986 - 169,662,545 (-)NCBIT2T-CHM13v2.0
Dact2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391714,415,492 - 14,424,595 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1714,415,314 - 14,424,566 (-)EnsemblGRCm39 Ensembl
GRCm381714,195,230 - 14,204,327 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1714,195,052 - 14,204,304 (-)EnsemblGRCm38mm10GRCm38
MGSCv371714,332,237 - 14,340,838 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361713,932,141 - 13,940,691 (-)NCBIMGSCv36mm8
Celera1714,996,218 - 15,004,819 (-)NCBICelera
Cytogenetic Map17A2NCBI
cM Map178.95NCBI
Dact2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554114,972,080 - 4,976,011 (+)NCBIChiLan1.0ChiLan1.0
DACT2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25188,545,838 - 188,559,378 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16186,426,272 - 186,440,162 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06166,295,983 - 166,308,361 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16171,240,869 - 171,247,797 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6171,237,795 - 171,247,797 (-)Ensemblpanpan1.1panPan2
PanPan1.1 Ensembl6171,237,795 - 171,247,797 (-)NCBIpanpan1.1panPan2
DACT2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1155,726,041 - 55,736,548 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl155,726,819 - 55,736,505 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha156,518,559 - 56,529,064 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0155,910,356 - 55,920,867 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl155,911,158 - 55,921,129 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1155,807,151 - 55,817,657 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0155,654,313 - 55,664,817 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0156,281,544 - 56,292,047 (-)NCBIUU_Cfam_GSD_1.0
Dact2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946150,115,283 - 150,127,362 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648917,370,341 - 17,379,327 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648917,370,190 - 17,379,327 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DACT2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl11,413,935 - 1,424,271 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.111,413,892 - 1,424,015 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.212,447,597 - 2,457,747 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DACT2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11396,141,847 - 96,152,677 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604067,980,856 - 67,991,621 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dact2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248504,402,057 - 4,411,417 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Dact2
69 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:67
Count of miRNA genes:54
Interacting mature miRNAs:61
Transcripts:ENSRNOT00000035125
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
738020Pia8Pristane induced arthritis QTL 84.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1165833076Rat
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)150910886060548Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
2302038Pia31Pristane induced arthritis QTL 315.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)11099206555992065Rat
1300167Hrtrt2Heart rate QTL 24.35heart pumping trait (VT:2000009)heart rate (CMO:0000002)11148131275088344Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)11148131282174945Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)11148131282174945Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)11148131282174945Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)11148131282174945Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
1578756Iddm22Insulin dependent diabetes mellitus QTL 222.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)11183518156835181Rat
634353Rends2Renal damage susceptibility QTL 20.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)11933357156983283Rat
724520Bp145Blood pressure QTL 1452.10.0024arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)12078482865784828Rat
1357400Bw62Body weight QTL624.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)12234064767340647Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)122340647102268831Rat
1331785Rf27Renal function QTL 274.643urine sodium amount (VT:0006274)urine sodium level (CMO:0000129)12887978078430678Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132356093162846471Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13273727390665040Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
1354599Bw29Body weight QTL 293.460.001body mass (VT:0001259)body weight (CMO:0000012)13344984878449848Rat
1354643Foco2Food consumption QTL 27.170.0001eating behavior trait (VT:0001431)food intake rate (CMO:0000427)13344984878449848Rat
8552900Pigfal1Plasma insulin-like growth factor 1 level QTL 17.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)13483685879836858Rat
8552948Pigfal11Plasma insulin-like growth factor 1 level QTL 114.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)13483685879836858Rat
9589820Insglur3Insulin/glucose ratio QTL 310.750.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)13483685879836858Rat
1331732Srn4Serum renin concentration QTL 44.467renin activity (VT:0005581)plasma renin activity level (CMO:0000116)13523959878430678Rat
1331792Rf29Renal function QTL 294.589urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)13523959878430678Rat
2313051Bss57Bone structure and strength QTL 573.70.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)143284731118944897Rat
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
2313072Bss53Bone structure and strength QTL 534.30.0001tibia length (VT:0004357)tibia length (CMO:0000450)143284731118944897Rat
2313078Bss54Bone structure and strength QTL 543.50.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
2313094Bss58Bone structure and strength QTL 583.70.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143284731118944897Rat
2313098Bmd70Bone mineral density QTL 703.60.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)143284731118944897Rat
2313099Bss56Bone structure and strength QTL 562.40.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143284731118944897Rat
2302059Pia36Pristane induced arthritis QTL 363.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)14333300288333002Rat
1331778Rf28Renal function QTL 284.66urine potassium amount (VT:0010539)urine potassium excretion rate (CMO:0000761)14580314078430678Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)148963584144267916Rat
4889962Bss94Bone structure and strength QTL 943.8tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)14936146582174945Rat
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)14939317294393172Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)15386304190532583Rat
4889919Bss86Bone structure and strength QTL 864.1tibia area (VT:1000281)tibia midshaft total cross-sectional area (CMO:0001715)15389511782174945Rat
4889929Bss87Bone structure and strength QTL 876.7tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)15389511782174945Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 1 1 14 33 22 10
Low 41 56 41 7 41 8 11 60 2 19 1 8
Below cutoff 2 10

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001107464 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006227960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006227962 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006227964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006227965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008758760 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017589095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039110742 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039110765 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BQ203833 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB729888 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB788616 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474033 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK473696 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215550 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000035125   ⟹   ENSRNOP00000030909
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl155,181,024 - 55,189,939 (-)Ensembl
Rnor_6.0 Ensembl156,159,436 - 56,168,351 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000080065   ⟹   ENSRNOP00000074246
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl155,181,024 - 55,191,096 (-)Ensembl
Rnor_6.0 Ensembl156,159,426 - 56,168,021 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000115787   ⟹   ENSRNOP00000092293
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl155,181,024 - 55,189,696 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000116341   ⟹   ENSRNOP00000078658
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl155,181,024 - 55,189,696 (-)Ensembl
RefSeq Acc Id: NM_001107464   ⟹   NP_001100934
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8163,854,182 - 63,863,098 (-)NCBI
mRatBN7.2155,181,023 - 55,189,939 (-)NCBI
Rnor_6.0156,159,435 - 56,168,351 (-)NCBI
Rnor_5.0157,354,080 - 57,364,005 (-)NCBI
RGSC_v3.4153,084,115 - 53,093,031 (-)RGD
Celera151,399,334 - 51,408,533 (-)RGD
Sequence:
RefSeq Acc Id: XM_006227960   ⟹   XP_006228022
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8163,854,182 - 63,862,741 (-)NCBI
mRatBN7.2155,181,023 - 55,189,588 (-)NCBI
Rnor_6.0156,159,435 - 56,167,192 (-)NCBI
Rnor_5.0157,354,080 - 57,364,005 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006227962   ⟹   XP_006228024
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8163,854,182 - 63,862,741 (-)NCBI
mRatBN7.2155,181,023 - 55,189,589 (-)NCBI
Rnor_6.0156,159,435 - 56,167,798 (-)NCBI
Rnor_5.0157,354,080 - 57,364,005 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006227964   ⟹   XP_006228026
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8163,854,182 - 63,862,746 (-)NCBI
mRatBN7.2155,181,023 - 55,189,588 (-)NCBI
Rnor_6.0156,159,435 - 56,168,097 (-)NCBI
Rnor_5.0157,354,080 - 57,364,005 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006227965   ⟹   XP_006228027
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8163,854,182 - 63,863,885 (-)NCBI
mRatBN7.2155,181,023 - 55,190,731 (-)NCBI
Rnor_6.0156,159,435 - 56,169,443 (-)NCBI
Rnor_5.0157,354,080 - 57,364,005 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017589095   ⟹   XP_017444584
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8163,854,182 - 63,862,741 (-)NCBI
mRatBN7.2155,181,023 - 55,189,589 (-)NCBI
Rnor_6.0156,159,435 - 56,168,097 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039110742   ⟹   XP_038966670
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8163,854,182 - 63,864,153 (-)NCBI
mRatBN7.2155,181,023 - 55,191,026 (-)NCBI
RefSeq Acc Id: XM_039110765   ⟹   XP_038966693
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8163,854,182 - 63,862,741 (-)NCBI
mRatBN7.2155,181,023 - 55,189,589 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001100934   ⟸   NM_001107464
- UniProtKB: D3ZSK6 (UniProtKB/TrEMBL),   A6KB18 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006228027   ⟸   XM_006227965
- Peptide Label: isoform X5
- UniProtKB: A0A0G2K7K6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006228026   ⟸   XM_006227964
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006228024   ⟸   XM_006227962
- Peptide Label: isoform X3
- UniProtKB: A0A8I6AGU3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006228022   ⟸   XM_006227960
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZNT5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017444584   ⟸   XM_017589095
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZNT5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000074246   ⟸   ENSRNOT00000080065
RefSeq Acc Id: ENSRNOP00000030909   ⟸   ENSRNOT00000035125
RefSeq Acc Id: XP_038966670   ⟸   XM_039110742
- Peptide Label: isoform X1
- UniProtKB: A6KB18 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038966693   ⟸   XM_039110765
- Peptide Label: isoform X3
- UniProtKB: A0A8I6AGU3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000078658   ⟸   ENSRNOT00000116341
RefSeq Acc Id: ENSRNOP00000092293   ⟸   ENSRNOT00000115787

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZSK6-F1-model_v2 AlphaFold D3ZSK6 1-768 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689635
Promoter ID:EPDNEW_R160
Type:initiation region
Name:Dact2_1
Description:dishevelled-binding antagonist of beta-catenin 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0156,168,322 - 56,168,382EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310742 AgrOrtholog
BioCyc Gene G2FUF-61338 BioCyc
Ensembl Genes ENSRNOG00000022921 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000035125 ENTREZGENE
  ENSRNOT00000035125.6 UniProtKB/TrEMBL
  ENSRNOT00000080065.2 UniProtKB/TrEMBL
  ENSRNOT00000115787.1 UniProtKB/TrEMBL
  ENSRNOT00000116341.1 UniProtKB/TrEMBL
InterPro Dapper UniProtKB/TrEMBL
KEGG Report rno:308212 UniProtKB/TrEMBL
NCBI Gene 308212 ENTREZGENE
PANTHER PTHR15919 UniProtKB/TrEMBL
  PTHR15919:SF13 UniProtKB/TrEMBL
Pfam Dapper UniProtKB/TrEMBL
PhenoGen Dact2 PhenoGen
RatGTEx ENSRNOG00000022921 RatGTEx
UniProt A0A0G2K7K6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZNT5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AGU3 ENTREZGENE, UniProtKB/TrEMBL
  A6KB18 ENTREZGENE, UniProtKB/TrEMBL
  D3ZSK6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-05-22 Dact2  dishevelled-binding antagonist of beta-catenin 2  Dact2  dapper, antagonist of beta-catenin, homolog 2 (Xenopus laevis)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-26 Dact2  dapper, antagonist of beta-catenin, homolog 2 (Xenopus laevis)  Dact2  dapper homolog 2, antagonist of beta-catenin (xenopus)   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Dact2  dapper homolog 2, antagonist of beta-catenin (xenopus)   Dact2_predicted  dapper homolog 2, antagonist of beta-catenin (xenopus) (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Dact2_predicted  dapper homolog 2, antagonist of beta-catenin (xenopus) (predicted)      Symbol and Name status set to approved 70820 APPROVED