Dact2 (dishevelled-binding antagonist of beta-catenin 2) - Rat Genome Database

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Gene: Dact2 (dishevelled-binding antagonist of beta-catenin 2) Rattus norvegicus
Analyze
Symbol: Dact2
Name: dishevelled-binding antagonist of beta-catenin 2
RGD ID: 1310742
Description: Predicted to enable several functions, including beta-catenin binding activity; delta-catenin binding activity; and protein kinase C binding activity. Predicted to be involved in several processes, including epithelial cell morphogenesis; inner medullary collecting duct development; and negative regulation of nodal signaling pathway. Predicted to act upstream of or within hematopoietic progenitor cell differentiation. Predicted to be active in cytoplasm. Orthologous to human DACT2 (dishevelled binding antagonist of beta catenin 2); PARTICIPATES IN transforming growth factor-beta Smad dependent signaling pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: dapper homolog 2; dapper homolog 2, antagonist of beta-catenin; dapper homolog 2, antagonist of beta-catenin (xenopus); dapper, antagonist of beta-catenin, homolog 2; dapper, antagonist of beta-catenin, homolog 2 (Xenopus laevis); LOC308212
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8163,854,182 - 63,864,153 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl163,854,182 - 63,864,255 (-)EnsemblGRCr8
mRatBN7.2155,181,023 - 55,191,026 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl155,181,024 - 55,191,096 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx160,052,775 - 60,061,679 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0168,709,151 - 68,718,086 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0161,962,725 - 61,971,629 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0156,159,435 - 56,169,443 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl156,159,426 - 56,168,351 (-)Ensemblrn6Rnor6.0
Rnor_5.0157,354,080 - 57,364,005 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4153,084,115 - 53,093,031 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera151,399,334 - 51,408,533 (-)NCBICelera
RGSC_v3.1153,087,456 - 53,098,585 (-)NCBI
Cytogenetic Map1q12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,4'-trichlorobiphenyl  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (EXP)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (EXP,ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
beta-lapachone  (ISO)
bexarotene  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
butanal  (ISO)
C60 fullerene  (EXP)
carbon nanotube  (ISO)
choline  (ISO)
chromium(6+)  (ISO)
ciguatoxin CTX1B  (ISO)
clofibrate  (EXP)
copper atom  (EXP)
copper(0)  (EXP)
diuron  (EXP)
endosulfan  (EXP)
ethanol  (ISO)
fenofibrate  (EXP)
flusilazole  (EXP)
folic acid  (ISO)
gemfibrozil  (EXP)
genistein  (ISO)
gentamycin  (EXP)
glycidol  (EXP)
hydralazine  (ISO)
indole-3-methanol  (EXP)
L-citrulline  (ISO)
L-methionine  (ISO)
lead(0)  (ISO)
methapyrilene  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N-nitrosodiethylamine  (EXP)
orphenadrine  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
PCB138  (ISO)
perfluorooctanoic acid  (EXP)
phenobarbital  (EXP)
pirinixic acid  (EXP)
pregnenolone 16alpha-carbonitrile  (EXP)
propiconazole  (EXP)
resveratrol  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
tamoxifen  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (EXP)
tetraphene  (ISO)
titanium dioxide  (ISO)
triadimefon  (EXP)
trichloroethene  (EXP)
trimellitic anhydride  (ISO)
triphenyl phosphate  (EXP)
urethane  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:17197390   PMID:18614015   PMID:18716284   PMID:20685821   PMID:21718540   PMID:24029230   PMID:35818217  


Genomics

Comparative Map Data
Dact2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8163,854,182 - 63,864,153 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl163,854,182 - 63,864,255 (-)EnsemblGRCr8
mRatBN7.2155,181,023 - 55,191,026 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl155,181,024 - 55,191,096 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx160,052,775 - 60,061,679 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0168,709,151 - 68,718,086 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0161,962,725 - 61,971,629 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0156,159,435 - 56,169,443 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl156,159,426 - 56,168,351 (-)Ensemblrn6Rnor6.0
Rnor_5.0157,354,080 - 57,364,005 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4153,084,115 - 53,093,031 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera151,399,334 - 51,408,533 (-)NCBICelera
RGSC_v3.1153,087,456 - 53,098,585 (-)NCBI
Cytogenetic Map1q12NCBI
DACT2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386168,292,830 - 168,319,777 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6168,292,830 - 168,319,777 (-)Ensemblhg38GRCh38
GRCh376168,693,510 - 168,720,457 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366168,450,433 - 168,463,251 (-)NCBIBuild 36Build 36hg18NCBI36
Build 346168,526,141 - 168,538,958NCBI
Celera6169,426,389 - 169,438,204 (-)NCBICelera
Cytogenetic Map6q27NCBI
HuRef6166,135,772 - 166,147,168 (-)NCBIHuRef
CHM1_16168,970,293 - 168,981,504 (-)NCBICHM1_1
T2T-CHM13v2.06169,636,986 - 169,662,545 (-)NCBIT2T-CHM13v2.0
Dact2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391714,415,492 - 14,424,595 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1714,415,314 - 14,424,566 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381714,195,230 - 14,204,327 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1714,195,052 - 14,204,304 (-)Ensemblmm10GRCm38
MGSCv371714,332,237 - 14,340,838 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361713,932,141 - 13,940,691 (-)NCBIMGSCv36mm8
Celera1714,996,218 - 15,004,819 (-)NCBICelera
Cytogenetic Map17A2NCBI
cM Map178.95NCBI
Dact2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554114,972,161 - 4,977,499 (+)Ensembl
ChiLan1.0NW_0049554114,972,080 - 4,976,011 (+)NCBIChiLan1.0ChiLan1.0
DACT2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25188,545,838 - 188,559,378 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16186,426,272 - 186,440,162 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06166,295,983 - 166,308,361 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16171,240,869 - 171,247,797 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6171,237,795 - 171,247,797 (-)EnsemblpanPan2panpan1.1
PanPan1.1 Ensembl6171,237,795 - 171,247,797 (-)NCBIpanPan2panpan1.1
DACT2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1155,726,041 - 55,736,548 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl155,726,819 - 55,736,505 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha156,518,559 - 56,529,064 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0155,910,356 - 55,920,867 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl155,911,158 - 55,921,129 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1155,807,151 - 55,817,657 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0155,654,313 - 55,664,817 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0156,281,544 - 56,292,047 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Dact2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946150,115,283 - 150,127,362 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648917,370,341 - 17,379,327 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493648917,370,190 - 17,379,327 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DACT2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl11,413,935 - 1,424,271 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.111,413,892 - 1,424,015 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.212,447,597 - 2,457,747 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DACT2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11396,141,847 - 96,152,677 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604067,980,856 - 67,991,621 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dact2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248504,402,057 - 4,411,417 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Dact2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v12183,630,020 - 183,639,561 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Dact2
58 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:67
Count of miRNA genes:54
Interacting mature miRNAs:61
Transcripts:ENSRNOT00000035125
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331732Srn4Serum renin concentration QTL 44.467renin activity (VT:0005581)plasma renin activity level (CMO:0000116)14345783787558729Rat
1357397Bw41Body weight QTL 414.190.0001body mass (VT:0001259)body weight (CMO:0000012)12940927974409279Rat
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)151940904101229020Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)139728272132889942Rat
4889929Bss87Bone structure and strength QTL 876.7tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)14630261591302615Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)151941022208479811Rat
1331792Rf29Renal function QTL 294.589urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)14345783787558729Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)14630261591302615Rat
8552900Pigfal1Plasma insulin-like growth factor 1 level QTL 17.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)14350995288509952Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)151940904168768703Rat
1354643Foco2Food consumption QTL 27.170.0001eating behavior trait (VT:0001431)food intake rate (CMO:0000427)14212296887122968Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134184556172281316Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)14630261591302615Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
1331778Rf28Renal function QTL 284.66urine potassium amount (VT:0010539)urine potassium excretion rate (CMO:0000761)14345783787558729Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)14630261591302615Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)151511344153680016Rat
1578756Iddm22Insulin dependent diabetes mellitus QTL 222.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)12050832665508326Rat
1331785Rf27Renal function QTL 274.643urine sodium amount (VT:0006274)urine sodium level (CMO:0000129)13070837587558729Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13456572679565726Rat
4889962Bss94Bone structure and strength QTL 943.8tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)15190920691302615Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)158769992103769992Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)14630261591302615Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
9589820Insglur3Insulin/glucose ratio QTL 310.750.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)14350995288509952Rat
152025249Scl82Serum cholesterol level QTL 824.77blood cholesterol amount (VT:0000180)152891222109116986Rat
1354599Bw29Body weight QTL 293.460.001body mass (VT:0001259)body weight (CMO:0000012)14212296887122968Rat
4889919Bss86Bone structure and strength QTL 864.1tibia area (VT:1000281)tibia midshaft total cross-sectional area (CMO:0001715)14630261591302615Rat
8552948Pigfal11Plasma insulin-like growth factor 1 level QTL 114.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)14350995288509952Rat
634353Rends2Renal damage susceptibility QTL 20.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)12065642065656420Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 153 91 90 59 39 59 6 303 139 11 130 81 92 31 16 16

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001107464 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006227960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006227962 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006227964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006227965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008758760 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017589095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039110742 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039110765 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BQ203833 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB729888 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB788616 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474033 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK473696 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215550 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000035125   ⟹   ENSRNOP00000030909
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl163,854,182 - 63,863,098 (-)Ensembl
mRatBN7.2 Ensembl155,181,024 - 55,189,939 (-)Ensembl
Rnor_6.0 Ensembl156,159,436 - 56,168,351 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000080065   ⟹   ENSRNOP00000074246
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl163,854,182 - 63,863,737 (-)Ensembl
mRatBN7.2 Ensembl155,181,024 - 55,191,096 (-)Ensembl
Rnor_6.0 Ensembl156,159,426 - 56,168,021 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000115787   ⟹   ENSRNOP00000092293
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl163,854,182 - 63,862,849 (-)Ensembl
mRatBN7.2 Ensembl155,181,024 - 55,189,696 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000116341   ⟹   ENSRNOP00000078658
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl163,854,182 - 63,862,020 (-)Ensembl
mRatBN7.2 Ensembl155,181,024 - 55,189,696 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000171067   ⟹   ENSRNOP00000105731
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl163,854,182 - 63,864,255 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000172192   ⟹   ENSRNOP00000112505
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl163,854,182 - 63,862,849 (-)Ensembl
RefSeq Acc Id: NM_001107464   ⟹   NP_001100934
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8163,854,182 - 63,863,098 (-)NCBI
mRatBN7.2155,181,023 - 55,189,939 (-)NCBI
Rnor_6.0156,159,435 - 56,168,351 (-)NCBI
Rnor_5.0157,354,080 - 57,364,005 (-)NCBI
RGSC_v3.4153,084,115 - 53,093,031 (-)RGD
Celera151,399,334 - 51,408,533 (-)RGD
Sequence:
RefSeq Acc Id: XM_006227960   ⟹   XP_006228022
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8163,854,182 - 63,862,741 (-)NCBI
mRatBN7.2155,181,023 - 55,189,588 (-)NCBI
Rnor_6.0156,159,435 - 56,167,192 (-)NCBI
Rnor_5.0157,354,080 - 57,364,005 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006227962   ⟹   XP_006228024
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8163,854,182 - 63,862,741 (-)NCBI
mRatBN7.2155,181,023 - 55,189,589 (-)NCBI
Rnor_6.0156,159,435 - 56,167,798 (-)NCBI
Rnor_5.0157,354,080 - 57,364,005 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006227964   ⟹   XP_006228026
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8163,854,182 - 63,862,746 (-)NCBI
mRatBN7.2155,181,023 - 55,189,588 (-)NCBI
Rnor_6.0156,159,435 - 56,168,097 (-)NCBI
Rnor_5.0157,354,080 - 57,364,005 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006227965   ⟹   XP_006228027
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8163,854,182 - 63,863,885 (-)NCBI
mRatBN7.2155,181,023 - 55,190,731 (-)NCBI
Rnor_6.0156,159,435 - 56,169,443 (-)NCBI
Rnor_5.0157,354,080 - 57,364,005 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017589095   ⟹   XP_017444584
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8163,854,182 - 63,862,741 (-)NCBI
mRatBN7.2155,181,023 - 55,189,589 (-)NCBI
Rnor_6.0156,159,435 - 56,168,097 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039110742   ⟹   XP_038966670
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8163,854,182 - 63,864,153 (-)NCBI
mRatBN7.2155,181,023 - 55,191,026 (-)NCBI
RefSeq Acc Id: XM_039110765   ⟹   XP_038966693
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8163,854,182 - 63,862,741 (-)NCBI
mRatBN7.2155,181,023 - 55,189,589 (-)NCBI
RefSeq Acc Id: NP_001100934   ⟸   NM_001107464
- UniProtKB: D3ZSK6 (UniProtKB/TrEMBL),   A6KB18 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006228027   ⟸   XM_006227965
- Peptide Label: isoform X5
- UniProtKB: A0A0G2K7K6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006228026   ⟸   XM_006227964
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006228024   ⟸   XM_006227962
- Peptide Label: isoform X3
- UniProtKB: A0A8I6AGU3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006228022   ⟸   XM_006227960
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZNT5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017444584   ⟸   XM_017589095
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZNT5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000074246   ⟸   ENSRNOT00000080065
Ensembl Acc Id: ENSRNOP00000030909   ⟸   ENSRNOT00000035125
RefSeq Acc Id: XP_038966670   ⟸   XM_039110742
- Peptide Label: isoform X1
- UniProtKB: A6KB18 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038966693   ⟸   XM_039110765
- Peptide Label: isoform X3
- UniProtKB: A0A8I6AGU3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000078658   ⟸   ENSRNOT00000116341
Ensembl Acc Id: ENSRNOP00000092293   ⟸   ENSRNOT00000115787
Ensembl Acc Id: ENSRNOP00000105731   ⟸   ENSRNOT00000171067
Ensembl Acc Id: ENSRNOP00000112505   ⟸   ENSRNOT00000172192

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZSK6-F1-model_v2 AlphaFold D3ZSK6 1-768 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689635
Promoter ID:EPDNEW_R160
Type:initiation region
Name:Dact2_1
Description:dishevelled-binding antagonist of beta-catenin 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0156,168,322 - 56,168,382EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310742 AgrOrtholog
BioCyc Gene G2FUF-61338 BioCyc
Ensembl Genes ENSRNOG00000022921 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000035125 ENTREZGENE
  ENSRNOT00000035125.7 UniProtKB/TrEMBL
  ENSRNOT00000080065 ENTREZGENE
  ENSRNOT00000080065.3 UniProtKB/TrEMBL
  ENSRNOT00000115787 ENTREZGENE
  ENSRNOT00000115787.2 UniProtKB/TrEMBL
  ENSRNOT00000116341 ENTREZGENE
  ENSRNOT00000116341.2 UniProtKB/TrEMBL
  ENSRNOT00000171067 ENTREZGENE
  ENSRNOT00000171067.1 UniProtKB/TrEMBL
  ENSRNOT00000172192 ENTREZGENE
  ENSRNOT00000172192.1 UniProtKB/TrEMBL
InterPro Dapper UniProtKB/TrEMBL
KEGG Report rno:308212 UniProtKB/TrEMBL
NCBI Gene 308212 ENTREZGENE
PANTHER PTHR15919 UniProtKB/TrEMBL
  PTHR15919:SF13 UniProtKB/TrEMBL
Pfam Dapper UniProtKB/TrEMBL
PhenoGen Dact2 PhenoGen
RatGTEx ENSRNOG00000022921 RatGTEx
UniProt A0A0G2K7K6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZNT5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AGU3 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LNG3_RAT UniProtKB/TrEMBL
  A0ABK0LPL7_RAT UniProtKB/TrEMBL
  A6KB18 ENTREZGENE, UniProtKB/TrEMBL
  D3ZSK6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-05-22 Dact2  dishevelled-binding antagonist of beta-catenin 2  Dact2  dapper, antagonist of beta-catenin, homolog 2 (Xenopus laevis)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-26 Dact2  dapper, antagonist of beta-catenin, homolog 2 (Xenopus laevis)  Dact2  dapper homolog 2, antagonist of beta-catenin (xenopus)   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Dact2  dapper homolog 2, antagonist of beta-catenin (xenopus)   Dact2_predicted  dapper homolog 2, antagonist of beta-catenin (xenopus) (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Dact2_predicted  dapper homolog 2, antagonist of beta-catenin (xenopus) (predicted)      Symbol and Name status set to approved 70820 APPROVED