Ccnyl1 (cyclin Y-like 1) - Rat Genome Database

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Pathways
Gene: Ccnyl1 (cyclin Y-like 1) Rattus norvegicus
Analyze
Symbol: Ccnyl1
Name: cyclin Y-like 1
RGD ID: 1310683
Description: Predicted to enable protein kinase binding activity. Predicted to be involved in neurogenesis and regulation of canonical Wnt signaling pathway. Predicted to act upstream of or within flagellated sperm motility and spermatogenesis. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to several human genes including CCNYL1 (cyclin Y like 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cyclin-Y-like protein 1; LOC316452; RGD1310683; similar to hypothetical protein FLJ40432
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8973,565,484 - 73,601,926 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl973,565,402 - 73,601,922 (+)EnsemblGRCr8
mRatBN7.2966,071,721 - 66,121,742 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl966,071,543 - 66,107,999 (+)EnsemblmRatBN7.2
Rnor_6.0971,398,186 - 71,434,581 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl971,398,710 - 71,434,493 (+)Ensemblrn6Rnor6.0
Rnor_5.0971,145,230 - 71,177,840 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4963,316,278 - 63,377,369 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera963,476,952 - 63,513,381 (+)NCBICelera
RGSC_v3.1963,498,495 - 63,522,320 (+)NCBI
Cytogenetic Map9q32NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
membrane  (IEA,ISO)
plasma membrane  (IBA,IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:26305884   PMID:26590424  


Genomics

Comparative Map Data
Ccnyl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8973,565,484 - 73,601,926 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl973,565,402 - 73,601,922 (+)EnsemblGRCr8
mRatBN7.2966,071,721 - 66,121,742 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl966,071,543 - 66,107,999 (+)EnsemblmRatBN7.2
Rnor_6.0971,398,186 - 71,434,581 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl971,398,710 - 71,434,493 (+)Ensemblrn6Rnor6.0
Rnor_5.0971,145,230 - 71,177,840 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4963,316,278 - 63,377,369 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera963,476,952 - 63,513,381 (+)NCBICelera
RGSC_v3.1963,498,495 - 63,522,320 (+)NCBI
Cytogenetic Map9q32NCBI
CCNYL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382207,711,640 - 207,756,174 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2207,711,524 - 207,761,839 (+)Ensemblhg38GRCh38
GRCh372208,576,364 - 208,620,898 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362208,284,509 - 208,327,434 (+)NCBIBuild 36Build 36hg18NCBI36
Celera2202,338,006 - 202,382,779 (+)NCBICelera
Cytogenetic Map2q33.3NCBI
HuRef2200,418,315 - 200,463,088 (+)NCBIHuRef
CHM1_12208,582,167 - 208,626,812 (+)NCBICHM1_1
T2T-CHM13v2.02208,185,841 - 208,230,386 (+)NCBIT2T-CHM13v2.0
Ccnyl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39164,729,963 - 64,764,805 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl164,729,614 - 64,764,803 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38164,691,041 - 64,725,646 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl164,690,455 - 64,725,644 (+)Ensemblmm10GRCm38
MGSCv37164,737,919 - 64,772,218 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36164,623,400 - 64,658,217 (+)NCBIMGSCv36mm8
Celera165,192,919 - 65,227,300 (+)NCBICelera
Cytogenetic Map1C2NCBI
cM Map132.74NCBI
Ccnyl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554577,294,696 - 7,328,773 (-)Ensembl
ChiLan1.0NW_0049554577,295,884 - 7,328,690 (-)NCBIChiLan1.0ChiLan1.0
CCNYL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213110,319,806 - 110,370,867 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B110,336,559 - 110,386,737 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B94,947,540 - 94,996,820 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B213,073,689 - 213,122,423 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B213,073,689 - 213,122,423 (+)EnsemblpanPan2panpan1.1
CCNYL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13716,075,459 - 16,113,583 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3716,075,372 - 16,110,926 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3716,958,908 - 16,997,042 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03716,010,480 - 16,048,609 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3716,010,519 - 16,047,305 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13715,956,302 - 15,994,435 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03715,929,416 - 15,967,509 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03715,938,661 - 15,976,790 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ccnyl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303164,238,898 - 164,267,810 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366313,867,407 - 3,904,997 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366313,867,403 - 3,905,423 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CCNYL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15110,874,211 - 110,910,887 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.115110,873,912 - 110,910,929 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215122,437,117 - 122,471,427 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CCNYL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11093,493,768 - 93,537,048 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1093,493,742 - 93,536,267 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666040105,833,261 - 105,876,820 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ccnyl1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247658,235,205 - 8,276,024 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Ccnyl1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v14138,574,824 - 138,610,452 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ccnyl1
362 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:17
Count of miRNA genes:17
Interacting mature miRNAs:17
Transcripts:ENSRNOT00000049411
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303170Bp332Blood pressure QTL 3323.730.027arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)9671488884474983Rat
631656Bp108Blood pressure QTL 1085.970.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)956047863101047863Rat
7411571Bw138Body weight QTL 13814.30.001body mass (VT:0001259)body weight gain (CMO:0000420)94002992585029925Rat
1582203Gluco19Glucose level QTL 193.30.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)963376862108376862Rat
724515Uae16Urinary albumin excretion QTL 168urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)965657365108376720Rat
8662828Vetf6Vascular elastic tissue fragility QTL 63.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)94445825699506504Rat
61450Ciaa3CIA Autoantibody QTL 36.5blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)92956766474567664Rat
1598834Memor11Memory QTL 112.5exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)94445825685262605Rat
70186Niddm26Non-insulin dependent diabetes mellitus QTL 263.87blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)92956766483835942Rat
70218Cm28Cardiac mass QTL 288.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)94172029586720295Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)964220169109220169Rat
1578760Cm53Cardiac mass QTL 533.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)964220169109220169Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)944458256121768150Rat
1581580Uae34Urinary albumin excretion QTL 34urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)964220169109220169Rat
1581517Bp284Blood pressure QTL 284arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)93922018684220186Rat
1300134Bp185Blood pressure QTL 1853.73arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)968875497121768150Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)948718864108376862Rat
1598849Memor17Memory QTL 172.2exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)95746049778547958Rat
7411656Foco26Food consumption QTL 269.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)94002992585029925Rat
1578757Pur6Proteinuria QTL 63.30.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)964220169109220169Rat
4889943Bss90Bone structure and strength QTL 904.1tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)95450650499506504Rat
1641894Alcrsp12Alcohol response QTL 12response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)93496059079960590Rat

Markers in Region
RH138746  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2966,107,789 - 66,107,950 (+)MAPPERmRatBN7.2
Rnor_6.0971,434,205 - 71,434,365NCBIRnor6.0
Rnor_5.0971,131,444 - 71,131,597NCBIRnor5.0
RGSC_v3.4963,376,993 - 63,377,153UniSTSRGSC3.4
Celera963,513,005 - 63,513,165UniSTS
RH 3.4 Map9537.6UniSTS
Cytogenetic Map9q32UniSTS
UniSTS:234144  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2966,106,551 - 66,106,655 (+)MAPPERmRatBN7.2
Rnor_6.0971,432,967 - 71,433,070NCBIRnor6.0
RGSC_v3.4963,375,754 - 63,375,857UniSTSRGSC3.4
Celera963,511,767 - 63,511,870UniSTS
Cytogenetic Map9q32UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 92 59 6 356 192 11 142 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000049411   ⟹   ENSRNOP00000047323
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl973,566,062 - 73,601,922 (+)Ensembl
mRatBN7.2 Ensembl966,071,543 - 66,107,999 (+)Ensembl
Rnor_6.0 Ensembl971,398,710 - 71,434,493 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000107904   ⟹   ENSRNOP00000082307
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl973,565,403 - 73,600,901 (+)Ensembl
mRatBN7.2 Ensembl966,071,543 - 66,107,999 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000165139   ⟹   ENSRNOP00000111658
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl973,565,402 - 73,600,363 (+)Ensembl
RefSeq Acc Id: XM_008767164   ⟹   XP_008765386
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8973,565,484 - 73,601,926 (+)NCBI
mRatBN7.2966,071,722 - 66,108,166 (+)NCBI
Rnor_6.0971,398,186 - 71,434,581 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063267898   ⟹   XP_063123968
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8973,566,119 - 73,601,926 (+)NCBI
Protein Sequences
Protein RefSeqs XP_008765386 (Get FASTA)   NCBI Sequence Viewer  
  XP_063123968 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL98876 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000047323
  ENSRNOP00000047323.5
  ENSRNOP00000082307.2
  ENSRNOP00000111658.1
RefSeq Acc Id: XP_008765386   ⟸   XM_008767164
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZUQ3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000047323   ⟸   ENSRNOT00000049411
Ensembl Acc Id: ENSRNOP00000082307   ⟸   ENSRNOT00000107904
RefSeq Acc Id: XP_063123968   ⟸   XM_063267898
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZUQ3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000111658   ⟸   ENSRNOT00000165139
Protein Domains
Cyclin-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1M4U0-F1-model_v2 AlphaFold F1M4U0 1-364 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696716
Promoter ID:EPDNEW_R7240
Type:single initiation site
Name:Ccnyl1_1
Description:cyclin Y-like 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0971,398,620 - 71,398,680EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310683 AgrOrtholog
BioCyc Gene G2FUF-27315 BioCyc
Ensembl Genes ENSRNOG00000023807 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000049411 ENTREZGENE
  ENSRNOT00000049411.7 UniProtKB/TrEMBL
  ENSRNOT00000107904.2 UniProtKB/TrEMBL
  ENSRNOT00000165139.1 UniProtKB/TrEMBL
Gene3D-CATH Cyclin-like UniProtKB/TrEMBL
InterPro Cyclin-like UniProtKB/TrEMBL
  Cyclin-like_sf UniProtKB/TrEMBL
  Cyclin_N UniProtKB/TrEMBL
  Cyclin_Y UniProtKB/TrEMBL
NCBI Gene 316452 ENTREZGENE
PANTHER CYCLIN Y, ISOFORM A UniProtKB/TrEMBL
Pfam Cyclin_N UniProtKB/TrEMBL
PhenoGen Ccnyl1 PhenoGen
PIRSF Cyclin_CG14939 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000023807 RatGTEx
SMART CYCLIN UniProtKB/TrEMBL
Superfamily-SCOP Cyclin_like UniProtKB/TrEMBL
UniProt A0A8I5ZUQ3 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LYE0_RAT UniProtKB/TrEMBL
  F1M4U0_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-02-27 Ccnyl1  cyclin Y-like 1  RGD1310683_predicted  similar to hypothetical protein FLJ40432 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 RGD1310683_predicted  similar to hypothetical protein FLJ40432 (predicted)  LOC316452_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC316452_predicted  similar to hypothetical protein FLJ40432 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL