Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Plxnb1 | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Plxnb1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of PLXNB1 mRNA | CTD | PMID:36331819 | Plxnb1 | Rat | 1,1-dichloroethene | decreases expression | ISO | Plxnb1 (Mus musculus) | 6480464 | vinylidene chloride results in decreased expression of PLXNB1 mRNA | CTD | PMID:26682919 | Plxnb1 | Rat | 1,2-dimethylhydrazine | increases expression | ISO | Plxnb1 (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in increased expression of PLXNB1 mRNA | CTD | PMID:22206623 | Plxnb1 | Rat | 1-naphthyl isothiocyanate | increases expression | EXP | | 6480464 | 1-Naphthylisothiocyanate results in increased expression of PLXNB1 mRNA | CTD | PMID:30723492 | Plxnb1 | Rat | 17beta-estradiol | increases expression | ISO | Plxnb1 (Mus musculus) | 6480464 | Estradiol results in increased expression of PLXNB1 mRNA | CTD | PMID:39298647 | Plxnb1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Plxnb1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of PLXNB1 mRNA | CTD | PMID:21570461 | Plxnb1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of PLXNB1 mRNA | CTD | PMID:33387578 | Plxnb1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Plxnb1 (Mus musculus) | 6480464 | [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in decreased expression more ... | CTD | PMID:25975270 | Plxnb1 | Rat | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | affects expression | ISO | Plxnb1 (Mus musculus) | 6480464 | 2,2',4,4',5-brominated diphenyl ether affects the expression of PLXNB1 mRNA | CTD | PMID:38648751 | Plxnb1 | Rat | 2-methylcholine | affects expression | ISO | PLXNB1 (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of PLXNB1 mRNA | CTD | PMID:21179406 | Plxnb1 | Rat | 3,3',5,5'-tetrabromobisphenol A | decreases expression | ISO | Plxnb1 (Mus musculus) | 6480464 | tetrabromobisphenol A results in decreased expression of PLXNB1 mRNA | CTD | PMID:25172293 | Plxnb1 | Rat | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | PLXNB1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] more ... | CTD | PMID:28628672 | Plxnb1 | Rat | 4,4'-diaminodiphenylmethane | increases expression | ISO | Plxnb1 (Mus musculus) | 6480464 | 4,4'-diaminodiphenylmethane results in increased expression of PLXNB1 mRNA | CTD | PMID:18648102 | Plxnb1 | Rat | 4,4'-sulfonyldiphenol | multiple interactions | ISO | PLXNB1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] more ... | CTD | PMID:28628672 | Plxnb1 | Rat | 4,4'-sulfonyldiphenol | affects methylation | ISO | Plxnb1 (Mus musculus) | 6480464 | bisphenol S affects the methylation of PLXNB1 gene | CTD | PMID:31683443 | Plxnb1 | Rat | 4,4'-sulfonyldiphenol | affects expression | ISO | PLXNB1 (Homo sapiens) | 6480464 | bisphenol S affects the expression of PLXNB1 protein | CTD | PMID:31945527 | Plxnb1 | Rat | 4,4'-sulfonyldiphenol | decreases expression | ISO | Plxnb1 (Mus musculus) | 6480464 | bisphenol S results in decreased expression of PLXNB1 mRNA | CTD | PMID:39298647 | Plxnb1 | Rat | 4,4'-sulfonyldiphenol | decreases methylation | ISO | Plxnb1 (Mus musculus) | 6480464 | bisphenol S results in decreased methylation of PLXNB1 exon | CTD | PMID:33297965 | Plxnb1 | Rat | 4-hydroxyphenyl retinamide | increases expression | ISO | Plxnb1 (Mus musculus) | 6480464 | Fenretinide results in increased expression of PLXNB1 mRNA | CTD | PMID:28973697 | Plxnb1 | Rat | acrolein | multiple interactions | ISO | PLXNB1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with Ozone] results in increased expression of PLXNB1 mRNA | CTD | PMID:32845096 | Plxnb1 | Rat | acrylamide | decreases expression | ISO | PLXNB1 (Homo sapiens) | 6480464 | Acrylamide results in decreased expression of PLXNB1 mRNA | CTD | PMID:32763439 | Plxnb1 | Rat | aflatoxin B1 | increases expression | ISO | Plxnb1 (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of PLXNB1 mRNA | CTD | PMID:19770486 | Plxnb1 | Rat | aflatoxin B1 | decreases methylation | ISO | PLXNB1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of PLXNB1 gene | CTD | PMID:27153756 | Plxnb1 | Rat | Aflatoxin B2 alpha | decreases methylation | ISO | PLXNB1 (Homo sapiens) | 6480464 | aflatoxin B2 results in decreased methylation of PLXNB1 exon | CTD | PMID:30157460 | Plxnb1 | Rat | alpha-Zearalanol | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of PLXNB1 mRNA | CTD | PMID:35163327 | Plxnb1 | Rat | arsenite(3-) | multiple interactions | ISO | PLXNB1 (Homo sapiens) | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to PLXNB1 mRNA] | CTD | PMID:32406909 | Plxnb1 | Rat | arsenous acid | increases expression | ISO | Plxnb1 (Mus musculus) | 6480464 | Arsenic Trioxide results in increased expression of PLXNB1 mRNA | CTD | PMID:35676786 | Plxnb1 | Rat | atrazine | decreases expression | ISO | PLXNB1 (Homo sapiens) | 6480464 | Atrazine results in decreased expression of PLXNB1 mRNA | CTD | PMID:22378314 | Plxnb1 | Rat | benzo[a]pyrene | affects methylation | ISO | PLXNB1 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of PLXNB1 promoter | CTD | PMID:27901495 | Plxnb1 | Rat | benzo[a]pyrene | decreases methylation | ISO | PLXNB1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of PLXNB1 5' UTR | CTD | PMID:27901495 | Plxnb1 | Rat | benzo[b]fluoranthene | increases expression | ISO | Plxnb1 (Mus musculus) | 6480464 | benzo(b)fluoranthene results in increased expression of PLXNB1 mRNA | CTD | PMID:26377693 | Plxnb1 | Rat | beta-lapachone | decreases expression | ISO | PLXNB1 (Homo sapiens) | 6480464 | beta-lapachone results in decreased expression of PLXNB1 mRNA | CTD | PMID:38218311 | Plxnb1 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of PLXNB1 mRNA | CTD | PMID:30816183|PMID:32145629 | Plxnb1 | Rat | bisphenol A | decreases expression | ISO | PLXNB1 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of PLXNB1 mRNA | CTD | PMID:36232920 | Plxnb1 | Rat | bisphenol A | increases methylation | ISO | PLXNB1 (Homo sapiens) | 6480464 | bisphenol A results in increased methylation of PLXNB1 gene | CTD | PMID:31601247 | Plxnb1 | Rat | bisphenol F | multiple interactions | ISO | PLXNB1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] more ... | CTD | PMID:28628672 | Plxnb1 | Rat | Brodifacoum | increases expression | EXP | | 6480464 | bromfenacoum results in increased expression of PLXNB1 protein | CTD | PMID:28903499 | Plxnb1 | Rat | butanal | decreases expression | ISO | PLXNB1 (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of PLXNB1 mRNA | CTD | PMID:26079696 | Plxnb1 | Rat | CGP 52608 | multiple interactions | ISO | PLXNB1 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to PLXNB1 gene] | CTD | PMID:28238834 | Plxnb1 | Rat | cisplatin | multiple interactions | ISO | PLXNB1 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of PLXNB1 mRNA | CTD | PMID:27392435 | Plxnb1 | Rat | clofibrate | decreases expression | ISO | Plxnb1 (Mus musculus) | 6480464 | Clofibrate results in decreased expression of PLXNB1 mRNA | CTD | PMID:23811191 | Plxnb1 | Rat | cobalt dichloride | decreases expression | ISO | PLXNB1 (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of PLXNB1 mRNA | CTD | PMID:19320972 | Plxnb1 | Rat | copper(II) chloride | decreases expression | ISO | PLXNB1 (Homo sapiens) | 6480464 | cupric chloride results in decreased expression of PLXNB1 mRNA | CTD | PMID:38568856 | Plxnb1 | Rat | copper(II) sulfate | decreases expression | ISO | PLXNB1 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of PLXNB1 mRNA | CTD | PMID:19549813 | Plxnb1 | Rat | cyclosporin A | decreases expression | ISO | PLXNB1 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of PLXNB1 mRNA | CTD | PMID:20106945 | Plxnb1 | Rat | dexamethasone | multiple interactions | ISO | PLXNB1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] more ... | CTD | PMID:28628672 | Plxnb1 | Rat | diarsenic trioxide | increases expression | ISO | Plxnb1 (Mus musculus) | 6480464 | Arsenic Trioxide results in increased expression of PLXNB1 mRNA | CTD | PMID:35676786 | Plxnb1 | Rat | diuron | decreases expression | EXP | | 6480464 | Diuron results in decreased expression of PLXNB1 mRNA | CTD | PMID:21551480 | Plxnb1 | Rat | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of PLXNB1 mRNA | CTD | PMID:29391264 | Plxnb1 | Rat | ethanol | affects splicing | ISO | Plxnb1 (Mus musculus) | 6480464 | Ethanol affects the splicing of PLXNB1 mRNA | CTD | PMID:30319688 | Plxnb1 | Rat | ethanol | increases expression | ISO | Plxnb1 (Mus musculus) | 6480464 | Ethanol results in increased expression of PLXNB1 mRNA | CTD | PMID:30319688 | Plxnb1 | Rat | folic acid | decreases expression | ISO | Plxnb1 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of PLXNB1 mRNA | CTD | PMID:25629700 | Plxnb1 | Rat | furan | increases expression | ISO | Plxnb1 (Mus musculus) | 6480464 | furan results in increased expression of PLXNB1 mRNA | CTD | PMID:24183702 | Plxnb1 | Rat | genistein | decreases expression | ISO | PLXNB1 (Homo sapiens) | 6480464 | Genistein results in decreased expression of PLXNB1 mRNA | CTD | PMID:16705744 | Plxnb1 | Rat | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of PLXNB1 mRNA | CTD | PMID:22061828 | Plxnb1 | Rat | glafenine | increases expression | EXP | | 6480464 | Glafenine results in increased expression of PLXNB1 mRNA | CTD | PMID:24136188 | Plxnb1 | Rat | indometacin | multiple interactions | ISO | PLXNB1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] more ... | CTD | PMID:28628672 | Plxnb1 | Rat | inulin | multiple interactions | ISO | Plxnb1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of PLXNB1 mRNA | CTD | PMID:36331819 | Plxnb1 | Rat | methotrexate | increases expression | ISO | PLXNB1 (Homo sapiens) | 6480464 | Methotrexate results in increased expression of PLXNB1 mRNA | CTD | PMID:17400583|PMID:21678067 | Plxnb1 | Rat | mono(2-ethylhexyl) phthalate | multiple interactions | ISO | Plxnb1 (Mus musculus) | 6480464 | [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-isobutyl more ... | CTD | PMID:39752319 | Plxnb1 | Rat | monobenzyl phthalate | multiple interactions | ISO | Plxnb1 (Mus musculus) | 6480464 | [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-isobutyl more ... | CTD | PMID:39752319 | Plxnb1 | Rat | Monobutylphthalate | multiple interactions | ISO | Plxnb1 (Mus musculus) | 6480464 | [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-isobutyl more ... | CTD | PMID:39752319 | Plxnb1 | Rat | monoethyl phthalate | multiple interactions | ISO | Plxnb1 (Mus musculus) | 6480464 | [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-isobutyl more ... | CTD | PMID:39752319 | Plxnb1 | Rat | N-methyl-4-phenylpyridinium | decreases expression | ISO | PLXNB1 (Homo sapiens) | 6480464 | 1-Methyl-4-phenylpyridinium results in decreased expression of PLXNB1 mRNA | CTD | PMID:25234470 | Plxnb1 | Rat | N-methyl-4-phenylpyridinium | affects expression | ISO | PLXNB1 (Homo sapiens) | 6480464 | 1-Methyl-4-phenylpyridinium affects the expression of PLXNB1 mRNA | CTD | PMID:25234470 | Plxnb1 | Rat | N-nitrosodiethylamine | increases expression | ISO | Plxnb1 (Mus musculus) | 6480464 | Diethylnitrosamine results in increased expression of PLXNB1 mRNA | CTD | PMID:24535843 | Plxnb1 | Rat | okadaic acid | decreases expression | ISO | PLXNB1 (Homo sapiens) | 6480464 | Okadaic Acid results in decreased expression of PLXNB1 mRNA | CTD | PMID:38832940 | Plxnb1 | Rat | organophosphorus compound | multiple interactions | EXP | | 6480464 | [Dust results in increased abundance of Organophosphorus Compounds] which results in increased expression of PLXNB1 more ... | CTD | PMID:39658253 | Plxnb1 | Rat | ozone | multiple interactions | ISO | PLXNB1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with Ozone] results in increased expression of PLXNB1 mRNA | CTD | PMID:32845096 | Plxnb1 | Rat | paracetamol | affects expression | ISO | Plxnb1 (Mus musculus) | 6480464 | Acetaminophen affects the expression of PLXNB1 mRNA | CTD | PMID:17562736 | Plxnb1 | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of PLXNB1 mRNA | CTD | PMID:33387578 | Plxnb1 | Rat | paracetamol | decreases expression | ISO | PLXNB1 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of PLXNB1 mRNA | CTD | PMID:21420995|PMID:29067470 | Plxnb1 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Plxnb1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of PLXNB1 mRNA; [perfluorooctane sulfonic more ... | CTD | PMID:36331819 | Plxnb1 | Rat | perfluorooctanoic acid | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of PLXNB1 mRNA | CTD | PMID:35163327 | Plxnb1 | Rat | phenobarbital | affects expression | ISO | PLXNB1 (Homo sapiens) | 6480464 | Phenobarbital affects the expression of PLXNB1 mRNA | CTD | PMID:19159669 | Plxnb1 | Rat | phenobarbital | affects expression | ISO | Plxnb1 (Mus musculus) | 6480464 | Phenobarbital affects the expression of PLXNB1 mRNA | CTD | PMID:23091169 | Plxnb1 | Rat | pirinixic acid | multiple interactions | ISO | Plxnb1 (Mus musculus) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in more ... | CTD | PMID:19710929|PMID:20813756 | Plxnb1 | Rat | pirinixic acid | decreases expression | ISO | Plxnb1 (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of PLXNB1 mRNA | CTD | PMID:20813756|PMID:23811191 | Plxnb1 | Rat | propiconazole | decreases expression | ISO | Plxnb1 (Mus musculus) | 6480464 | propiconazole results in decreased expression of PLXNB1 mRNA | CTD | PMID:21278054 | Plxnb1 | Rat | silicon dioxide | decreases expression | ISO | PLXNB1 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in decreased expression of PLXNB1 mRNA | CTD | PMID:25895662 | Plxnb1 | Rat | sodium arsenite | decreases expression | ISO | PLXNB1 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of PLXNB1 mRNA | CTD | PMID:38568856 | Plxnb1 | Rat | sodium arsenite | increases expression | ISO | PLXNB1 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of PLXNB1 protein | CTD | PMID:38228842 | Plxnb1 | Rat | Soman | decreases expression | EXP | | 6480464 | Soman results in decreased expression of PLXNB1 mRNA | CTD | PMID:19281266 | Plxnb1 | Rat | temozolomide | increases expression | ISO | PLXNB1 (Homo sapiens) | 6480464 | Temozolomide results in increased expression of PLXNB1 mRNA | CTD | PMID:31758290 | Plxnb1 | Rat | thiram | decreases expression | ISO | PLXNB1 (Homo sapiens) | 6480464 | Thiram results in decreased expression of PLXNB1 mRNA | CTD | PMID:38568856 | Plxnb1 | Rat | titanium dioxide | increases expression | ISO | Plxnb1 (Mus musculus) | 6480464 | titanium dioxide results in increased expression of PLXNB1 mRNA | CTD | PMID:23557971 | Plxnb1 | Rat | titanium dioxide | increases methylation | ISO | Plxnb1 (Mus musculus) | 6480464 | titanium dioxide results in increased methylation of PLXNB1 gene | CTD | PMID:35295148 | Plxnb1 | Rat | titanium dioxide | decreases methylation | ISO | Plxnb1 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of PLXNB1 gene | CTD | PMID:35295148 | Plxnb1 | Rat | titanium dioxide | decreases expression | ISO | Plxnb1 (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of PLXNB1 mRNA | CTD | PMID:29264374 | Plxnb1 | Rat | valproic acid | increases methylation | ISO | PLXNB1 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of PLXNB1 gene | CTD | PMID:29154799 | Plxnb1 | Rat | valproic acid | decreases expression | ISO | PLXNB1 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of PLXNB1 mRNA | CTD | PMID:29154799 | Plxnb1 | Rat | vinclozolin | affects expression | EXP | | 6480464 | vinclozolin affects the expression of PLXNB1 mRNA | CTD | PMID:19015723 | Plxnb1 | Rat | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of PLXNB1 mRNA | CTD | PMID:23034163 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















