Plekhf1 (pleckstrin homology and FYVE domain containing 1) - Rat Genome Database

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Gene: Plekhf1 (pleckstrin homology and FYVE domain containing 1) Rattus norvegicus
Analyze
Symbol: Plekhf1
Name: pleckstrin homology and FYVE domain containing 1
RGD ID: 1310544
Description: Predicted to enable phosphatidylinositol-3-phosphate binding activity; phosphatidylinositol-4-phosphate binding activity; and phosphatidylinositol-5-phosphate binding activity. Predicted to be involved in several processes, including endosome organization; endosome to lysosome transport; and protein localization to plasma membrane. Predicted to be located in endosome. Predicted to be active in early endosome and lysosome. Orthologous to human PLEKHF1 (pleckstrin homology and FYVE domain containing 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC308543; PH domain-containing family F member 1; pleckstrin homology domain containing, family F (with FYVE domain) member 1; pleckstrin homology domain-containing family F member 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81100,045,340 - 100,046,817 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1100,027,056 - 100,053,452 (-)EnsemblGRCr8
mRatBN7.2190,908,304 - 90,915,862 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl190,904,742 - 90,915,820 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx196,304,107 - 96,305,583 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01104,769,821 - 104,771,297 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0198,062,634 - 98,064,111 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0194,609,041 - 94,616,565 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl194,609,377 - 94,610,854 (-)Ensemblrn6Rnor6.0
Rnor_5.0195,700,153 - 95,707,361 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4190,697,260 - 90,698,737 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera185,240,535 - 85,242,012 (-)NCBICelera
RGSC_v3.1190,775,372 - 90,776,840 (-)NCBI
Cytogenetic Map1q21NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
(S)-colchicine  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrylamide  (ISO)
adenine  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (EXP,ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
buta-1,3-diene  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
chloroprene  (ISO)
chlorpyrifos  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
cobalt dichloride  (EXP,ISO)
Cuprizon  (EXP)
cypermethrin  (ISO)
DDE  (ISO)
decabromodiphenyl ether  (ISO)
dexamethasone  (ISO)
diazinon  (EXP)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
dieldrin  (EXP)
dimethyl sulfoxide  (ISO)
diuron  (EXP)
doxorubicin  (ISO)
endosulfan  (EXP)
epoxiconazole  (ISO)
ethyl methanesulfonate  (ISO)
fenthion  (ISO)
ferric oxide  (ISO)
fluoranthene  (ISO)
flutamide  (EXP)
furan  (EXP)
glyphosate  (ISO)
indometacin  (ISO)
methamphetamine  (EXP)
methyl methanesulfonate  (ISO)
nickel dichloride  (EXP)
okadaic acid  (ISO)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
pirinixic acid  (ISO)
propanal  (ISO)
propiconazole  (ISO)
resveratrol  (ISO)
SCH 23390  (EXP)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sulindac  (ISO)
temozolomide  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichloroethene  (ISO)
triphenyl phosphate  (ISO)
Triptolide  (ISO)
troglitazone  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:15489334   PMID:22115783  


Genomics

Comparative Map Data
Plekhf1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81100,045,340 - 100,046,817 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1100,027,056 - 100,053,452 (-)EnsemblGRCr8
mRatBN7.2190,908,304 - 90,915,862 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl190,904,742 - 90,915,820 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx196,304,107 - 96,305,583 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01104,769,821 - 104,771,297 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0198,062,634 - 98,064,111 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0194,609,041 - 94,616,565 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl194,609,377 - 94,610,854 (-)Ensemblrn6Rnor6.0
Rnor_5.0195,700,153 - 95,707,361 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4190,697,260 - 90,698,737 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera185,240,535 - 85,242,012 (-)NCBICelera
RGSC_v3.1190,775,372 - 90,776,840 (-)NCBI
Cytogenetic Map1q21NCBI
PLEKHF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381929,665,461 - 29,675,477 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1929,665,398 - 29,675,477 (+)Ensemblhg38GRCh38
GRCh371930,156,368 - 30,166,384 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361934,848,167 - 34,858,224 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341934,847,802 - 34,858,204NCBI
Celera1926,854,527 - 26,864,585 (+)NCBICelera
Cytogenetic Map19q12NCBI
HuRef1926,668,787 - 26,678,845 (+)NCBIHuRef
CHM1_11930,157,659 - 30,167,716 (+)NCBICHM1_1
T2T-CHM13v2.01932,191,180 - 32,201,225 (+)NCBIT2T-CHM13v2.0
Plekhf1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39737,920,078 - 37,927,418 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl737,916,396 - 37,927,440 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38738,220,654 - 38,227,994 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl738,216,972 - 38,228,016 (-)Ensemblmm10GRCm38
MGSCv37739,005,673 - 39,013,013 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36737,929,761 - 37,937,047 (-)NCBIMGSCv36mm8
Celera733,384,111 - 33,391,399 (-)NCBICelera
Cytogenetic Map7B3NCBI
cM Map725.36NCBI
Plekhf1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554687,934,024 - 7,943,499 (-)Ensembl
ChiLan1.0NW_0049554687,934,024 - 7,943,499 (-)NCBIChiLan1.0ChiLan1.0
PLEKHF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22035,646,442 - 35,656,852 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11937,643,651 - 37,653,763 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01926,593,833 - 26,604,514 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11935,354,315 - 35,364,366 (+)NCBIPanPan1.1PanPan1.1panPan2
PLEKHF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11121,776,122 - 121,802,881 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1121,781,181 - 121,782,578 (-)NCBIcanFam3CanFam3.1
CanFam3.1 Ensembl1121,781,181 - 121,782,578 (-)EnsemblcanFam3CanFam3.1
ROS_Cfam_1.01122,402,959 - 122,431,800 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1122,409,980 - 122,411,377 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11121,982,589 - 122,011,226 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01121,595,581 - 121,618,885 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01122,654,118 - 122,682,943 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Plekhf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244093495,976,223 - 5,987,835 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365705,658,052 - 5,666,358 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365705,658,052 - 5,666,711 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLEKHF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl639,786,199 - 39,797,583 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1639,786,201 - 39,797,578 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2635,145,695 - 35,157,120 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PLEKHF1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1624,732,774 - 24,743,636 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl624,742,024 - 24,742,863 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660732,264,800 - 2,275,582 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Plekhf1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247944,843,635 - 4,852,346 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247944,843,342 - 4,852,346 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Plekhf1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v12160,417,988 - 160,425,609 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Plekhf1
8 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:61
Count of miRNA genes:59
Interacting mature miRNAs:60
Transcripts:ENSRNOT00000020383
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)151940904101229020Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)187889942132889942Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)139728272132889942Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)151941022208479811Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)151940904168768703Rat
2300324Fetw1Fetal weight QTL 112.10.005fetal growth trait (VT:0004201)fetal body weight (CMO:0002080)192963855109494029Rat
1331800Scl25Serum cholesterol level QTL 253.013blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)187785026142582336Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183019780128019780Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)166404680111404680Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134184556172281316Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)166009857160501508Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
631519Pia11Pristane induced arthritis QTL 115.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)193903998191260518Rat
1302788Scl19Serum cholesterol QTL 194.60.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)166400974132889942Rat
1549903Bp267Blood pressure QTL 267arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)184107164115183752Rat
2313083Bmd74Bone mineral density QTL 7440.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)191302413136302413Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)151511344153680016Rat
724521Uae1Urinary albumin excretion QTL 13.80.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)199645382182701046Rat
1358902Bw47Body weight QTL 471.67body mass (VT:0001259)body weight (CMO:0000012)199645382221502378Rat
1358192Ept13Estrogen-induced pituitary tumorigenesis QTL 133.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)186622262131622262Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)158769992103769992Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)166077886111077886Rat
631205Bp196Blood pressure QTL 19640.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)198879955208479939Rat
738022Anxrr13Anxiety related response QTL 134.60.00039locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of, or within a discrete space in an open field apparatus (CMO:0001514)192683681137683681Rat
152025249Scl82Serum cholesterol level QTL 824.77blood cholesterol amount (VT:0000180)152891222109116986Rat
10054135Gmadr2Adrenal mass QTL 21.970.0129adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)186993904131993904Rat
7411712Strs4Sensitivity to stroke QTL 48.7cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)187558587132558587Rat
1331749Hrtrt11Heart rate QTL 112.973heart pumping trait (VT:2000009)heart rate (CMO:0000002)192683681137683681Rat
737977Bp160Blood pressure QTL 1600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)197582336142582336Rat
724529Cm16Cardiac mass QTL 162.7heart mass (VT:0007028)calculated heart weight (CMO:0000073)196717367160111531Rat

Markers in Region
RH129691  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2190,908,685 - 90,908,890 (+)MAPPERmRatBN7.2
Rnor_6.0194,609,423 - 94,609,627NCBIRnor6.0
Rnor_5.0195,700,222 - 95,700,426UniSTSRnor5.0
RGSC_v3.4190,697,308 - 90,697,512UniSTSRGSC3.4
Celera185,240,583 - 85,240,787UniSTS
RH 3.4 Map1882.2UniSTS
Cytogenetic Map1q22UniSTS
RH137172  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2190,908,725 - 90,908,919 (+)MAPPERmRatBN7.2
Rnor_6.0194,609,463 - 94,609,656NCBIRnor6.0
Rnor_5.0195,700,262 - 95,700,455UniSTSRnor5.0
RGSC_v3.4190,697,348 - 90,697,541UniSTSRGSC3.4
Celera185,240,623 - 85,240,816UniSTS
RH 3.4 Map1884.59UniSTS
Cytogenetic Map1q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 161 91 90 59 83 59 6 347 183 11 140 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000020383   ⟹   ENSRNOP00000020352
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl190,908,316 - 90,915,068 (-)Ensembl
Rnor_6.0 Ensembl194,609,377 - 94,610,854 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000108120   ⟹   ENSRNOP00000081760
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1100,044,706 - 100,053,452 (-)Ensembl
mRatBN7.2 Ensembl190,908,316 - 90,910,629 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000113101   ⟹   ENSRNOP00000091851
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1100,027,360 - 100,052,533 (-)Ensembl
mRatBN7.2 Ensembl190,904,742 - 90,915,820 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000136516   ⟹   ENSRNOP00000108060
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1100,027,056 - 100,052,663 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000153146   ⟹   ENSRNOP00000111805
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1100,035,395 - 100,052,669 (-)Ensembl
RefSeq Acc Id: NM_001013148   ⟹   NP_001013166
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81100,045,340 - 100,046,817 (-)NCBI
mRatBN7.2190,908,638 - 90,910,115 (-)NCBI
Rnor_6.0194,609,375 - 94,610,852 (-)NCBI
Rnor_5.0195,700,153 - 95,707,361 (-)NCBI
RGSC_v3.4190,697,260 - 90,698,737 (-)RGD
Celera185,240,535 - 85,242,012 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001013166 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH79354 (Get FASTA)   NCBI Sequence Viewer  
  EDM07589 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000020352.3
  ENSRNOP00000081760
  ENSRNOP00000081760.1
  ENSRNOP00000091851.1
GenBank Protein Q68FU1 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001013166   ⟸   NM_001013148
- UniProtKB: Q68FU1 (UniProtKB/Swiss-Prot),   A6JAE5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000020352   ⟸   ENSRNOT00000020383
Ensembl Acc Id: ENSRNOP00000081760   ⟸   ENSRNOT00000108120
Ensembl Acc Id: ENSRNOP00000091851   ⟸   ENSRNOT00000113101
Ensembl Acc Id: ENSRNOP00000111805   ⟸   ENSRNOT00000153146
Ensembl Acc Id: ENSRNOP00000108060   ⟸   ENSRNOT00000136516
Protein Domains
FYVE-type   PH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q68FU1-F1-model_v2 AlphaFold Q68FU1 1-279 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310544 AgrOrtholog
BioCyc Gene G2FUF-59935 BioCyc
Ensembl Genes ENSRNOG00000027724 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000020383.6 UniProtKB/Swiss-Prot
  ENSRNOT00000108120 ENTREZGENE
  ENSRNOT00000108120.1 UniProtKB/Swiss-Prot
  ENSRNOT00000113101.1 UniProtKB/Swiss-Prot
Gene3D-CATH 2.30.29.30 UniProtKB/Swiss-Prot
  3.30.40.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7108247 IMAGE-MGC_LOAD
InterPro PH-like_dom_sf UniProtKB/Swiss-Prot
  PH_domain UniProtKB/Swiss-Prot
  PH_domain-containing_F UniProtKB/Swiss-Prot
  PH_Phafin UniProtKB/Swiss-Prot
  PKHF1_FYVE UniProtKB/Swiss-Prot
  Znf_FYVE UniProtKB/Swiss-Prot
  Znf_FYVE-rel UniProtKB/Swiss-Prot
  Znf_FYVE_PHD UniProtKB/Swiss-Prot
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot
KEGG Report rno:308543 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94811 IMAGE-MGC_LOAD
NCBI Gene 308543 ENTREZGENE
PANTHER PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY F MEMBER 1 UniProtKB/Swiss-Prot
  PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY F MEMBER 2-RELATED UniProtKB/Swiss-Prot
Pfam FYVE UniProtKB/Swiss-Prot
  PF00169 UniProtKB/Swiss-Prot
PhenoGen Plekhf1 PhenoGen
PROSITE PH_DOMAIN UniProtKB/Swiss-Prot
  ZF_FYVE UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000027724 RatGTEx
SMART FYVE UniProtKB/Swiss-Prot
  SM00233 UniProtKB/Swiss-Prot
Superfamily-SCOP PH domain-like UniProtKB/Swiss-Prot
  SSF57903 UniProtKB/Swiss-Prot
UniProt A6JAE5 ENTREZGENE, UniProtKB/TrEMBL
  PKHF1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-30 Plekhf1  pleckstrin homology and FYVE domain containing 1  Plekhf1  pleckstrin homology domain containing, family F (with FYVE domain) member 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Plekhf1  pleckstrin homology domain containing, family F (with FYVE domain) member 1  Plekhf1_predicted  pleckstrin homology domain containing, family F (with FYVE domain) member 1 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Plekhf1_predicted  pleckstrin homology domain containing, family F (with FYVE domain) member 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED