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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1310544
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Plekhf1
Name: pleckstrin homology and FYVE domain containing 1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Plekhf1decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of PLEKHF1 mRNAPMID:34947998
Plekhf1increases expressionEXP 6480464CTDbisphenol A results in increased expression of PLEKHF1 mRNAPMID:25181051 PMID:30816183 PMID:32145629 PMID:32528016
Plekhf1decreases expressionISOPLEKHF1 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of PLEKHF1 proteinPMID:31675489
Plekhf1increases expressionISOPLEKHF1 (Homo sapiens)6480464CTDbisphenol A results in increased expression of PLEKHF1 mRNAPMID:29275510
Plekhf1increases expressionISOPlekhf1 (Mus musculus)6480464CTDbisphenol A results in increased expression of PLEKHF1 mRNAPMID:32156529 PMID:33221593
Plekhf1multiple interactionsISOPLEKHF1 (Homo sapiens)6480464CTD[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of PLEKHF1 mRNAPMID:28628672
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