Mpv17 (mitochondrial inner membrane protein MPV17) - Rat Genome Database

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Pathways
Gene: Mpv17 (mitochondrial inner membrane protein MPV17) Rattus norvegicus
Analyze
Symbol: Mpv17
Name: mitochondrial inner membrane protein MPV17
RGD ID: 1310512
Description: Predicted to enable channel activity. Predicted to be involved in several processes, including cellular response to reactive oxygen species; glomerular basement membrane development; and regulation of mitochondrial DNA metabolic process. Predicted to act upstream of or within reactive oxygen species metabolic process and sensory perception of sound. Predicted to be located in mitochondrial inner membrane and peroxisome. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 2EE and mitochondrial DNA depletion syndrome 6. Orthologous to human MPV17 (mitochondrial inner membrane protein MPV17); INTERACTS WITH atrazine; bisphenol A; paracetamol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC360463; MpV17 mitochondrial inner membrane protein; MPV17 mitochondrial membrane protein-like; Mpv17 transgene, kidney disease mutant-like; Mpv17l
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8630,941,693 - 30,956,389 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl630,943,356 - 30,956,386 (+)EnsemblGRCr8
mRatBN7.2625,221,668 - 25,236,241 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl625,222,896 - 25,236,244 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx625,523,972 - 25,537,065 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0625,839,865 - 25,852,958 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0625,318,528 - 25,331,843 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0626,585,713 - 26,600,265 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl626,587,443 - 26,599,511 (+)Ensemblrn6Rnor6.0
Rnor_5.0636,403,896 - 36,416,645 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4625,200,452 - 25,214,909 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera624,714,225 - 24,727,365 (+)NCBICelera
RGSC_v3.1101,655,564 - 1,672,677 (+)NCBI
Cytogenetic Map6q14NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA)
membrane  (IEA)
mitochondrial inner membrane  (IEA,ISO)
mitochondrion  (IBA,IEA,ISO)
peroxisome  (ISO)

Molecular Function
channel activity  (IBA,IEA,ISO,ISS)
protein binding  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7957077   PMID:12477932   PMID:16041630   PMID:16582910   PMID:18614015   PMID:25861990   PMID:26123482   PMID:26760297  


Genomics

Comparative Map Data
Mpv17
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8630,941,693 - 30,956,389 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl630,943,356 - 30,956,386 (+)EnsemblGRCr8
mRatBN7.2625,221,668 - 25,236,241 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl625,222,896 - 25,236,244 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx625,523,972 - 25,537,065 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0625,839,865 - 25,852,958 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0625,318,528 - 25,331,843 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0626,585,713 - 26,600,265 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl626,587,443 - 26,599,511 (+)Ensemblrn6Rnor6.0
Rnor_5.0636,403,896 - 36,416,645 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4625,200,452 - 25,214,909 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera624,714,225 - 24,727,365 (+)NCBICelera
RGSC_v3.1101,655,564 - 1,672,677 (+)NCBI
Cytogenetic Map6q14NCBI
MPV17
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38227,309,492 - 27,323,097 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl227,309,486 - 27,325,680 (-)Ensemblhg38GRCh38
GRCh37227,532,360 - 27,545,964 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36227,385,864 - 27,399,473 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34227,444,012 - 27,457,082NCBI
Celera227,379,464 - 27,393,076 (-)NCBICelera
Cytogenetic Map2p23.3NCBI
HuRef227,274,582 - 27,288,152 (-)NCBIHuRef
CHM1_1227,462,306 - 27,475,919 (-)NCBICHM1_1
T2T-CHM13v2.0227,351,915 - 27,365,520 (-)NCBIT2T-CHM13v2.0
Mpv17
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39531,298,007 - 31,311,595 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl531,297,998 - 31,311,595 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38531,140,663 - 31,154,251 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl531,140,654 - 31,154,251 (-)Ensemblmm10GRCm38
MGSCv37531,443,033 - 31,456,615 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36531,417,529 - 31,430,812 (-)NCBIMGSCv36mm8
Celera528,619,571 - 28,633,245 (-)NCBICelera
Cytogenetic Map5B1NCBI
cM Map517.12NCBI
Mpv17
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554699,279,540 - 9,291,954 (-)Ensembl
ChiLan1.0NW_0049554699,279,540 - 9,292,012 (-)NCBIChiLan1.0ChiLan1.0
MPV17
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21299,189,334 - 99,202,979 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A99,193,303 - 99,206,947 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A27,311,551 - 27,325,249 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A27,399,258 - 27,412,747 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A27,399,258 - 27,414,090 (-)EnsemblpanPan2panpan1.1
MPV17
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11721,280,523 - 21,290,967 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1721,281,361 - 21,290,339 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1721,172,324 - 21,182,712 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01721,601,802 - 21,612,194 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1721,601,804 - 21,612,150 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11721,288,497 - 21,298,885 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01721,297,995 - 21,308,610 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01721,346,222 - 21,356,615 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Mpv17
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629265,580,429 - 65,593,085 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364935,248,059 - 5,258,147 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364935,246,803 - 5,258,147 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MPV17
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3111,821,690 - 111,833,928 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.13111,823,075 - 111,833,929 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
MPV17
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11480,289,285 - 80,302,838 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604531,849,129 - 31,863,229 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mpv17
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247389,395,416 - 9,407,223 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247389,395,315 - 9,411,904 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Mpv17
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1722,931,697 - 22,944,762 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Mpv17
95 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:34
Count of miRNA genes:31
Interacting mature miRNAs:34
Transcripts:ENSRNOT00000034207
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8552962Pigfal16Plasma insulin-like growth factor 1 level QTL 169.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)6197587946975879Rat
10401812Kidm54Kidney mass QTL 54kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)62009763565097635Rat
8552910Pigfal5Plasma insulin-like growth factor 1 level QTL 54.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)62265388967653889Rat
10401800Kidm49Kidney mass QTL 49kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)62009763565097635Rat
1300164Rf15Renal function QTL 153.12renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6323998948239989Rat
9589129Insul24Insulin level QTL 2419.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)6197587946975879Rat
7411603Foco13Food consumption QTL 135.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)6197587946975879Rat
1598843Cm63Cardiac mass QTL 632.6heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)6144788383Rat
7411542Bw127Body weight QTL 1275.50.001body mass (VT:0001259)body weight gain (CMO:0000420)6197587946975879Rat
2292616Ept15Estrogen-induced pituitary tumorigenesis QTL 154.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)6144788383Rat
9589048Scfw3Subcutaneous fat weight QTL 34.570.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)6197587946975879Rat
2293839Kiddil2Kidney dilation QTL 24.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62661831486868070Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)620859430113082285Rat
2301964Bp323Blood pressure QTL 3234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6186868070Rat
2293709Bss23Bone structure and strength QTL 235.180.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)6323998948239989Rat
2293650Bss31Bone structure and strength QTL 315.050.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)6323998948239989Rat
2293841Kiddil4Kidney dilation QTL 44.4kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62661831486868070Rat
1300128Rf16Renal function QTL 163.89renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6140163351Rat
1641898Colcr4Colorectal carcinoma resistance QTL43.710.0007intestine integrity trait (VT:0010554)well differentiated malignant colorectal tumor surface area measurement (CMO:0002077)63093763275937632Rat
70199Coreg1Compensatory renal growth QTL 111.8kidney mass (VT:0002707)compensatory renal growth score (CMO:0001894)61459947363457687Rat
2301972Bp325Blood pressure QTL 3254.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)61608937261967788Rat
1358190Ept1Estrogen-induced pituitary tumorigenesis QTL 14.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)6144788383Rat
2293656Bss28Bone structure and strength QTL 286.790.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)6323998948239989Rat
1359023Bp272Blood pressure QTL 2722.5arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)62228825732981219Rat
1354664Slep2Serum leptin concentration QTL 24.49blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)62228825767288257Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001098240 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008764515 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008764516 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008764517 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008764519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594206 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594207 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594208 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594209 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594210 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594211 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594212 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112437 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112438 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112439 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112440 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112441 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112443 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112444 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112445 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262038 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262039 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262040 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262041 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262042 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262043 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC091193 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000034207   ⟹   ENSRNOP00000037647
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl630,943,356 - 30,956,386 (+)Ensembl
mRatBN7.2 Ensembl625,222,896 - 25,232,622 (+)Ensembl
Rnor_6.0 Ensembl626,587,443 - 26,599,511 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000095043   ⟹   ENSRNOP00000079234
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl630,943,356 - 30,955,505 (+)Ensembl
mRatBN7.2 Ensembl625,222,896 - 25,235,539 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000099208   ⟹   ENSRNOP00000091585
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl630,943,356 - 30,956,199 (+)Ensembl
mRatBN7.2 Ensembl625,222,968 - 25,236,244 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000102606   ⟹   ENSRNOP00000092589
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl630,943,356 - 30,956,199 (+)Ensembl
mRatBN7.2 Ensembl625,222,968 - 25,236,244 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000151554   ⟹   ENSRNOP00000111931
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl630,943,356 - 30,953,333 (+)Ensembl
RefSeq Acc Id: NM_001098240   ⟹   NP_001091710
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8630,943,110 - 30,956,207 (+)NCBI
mRatBN7.2625,223,143 - 25,236,241 (+)NCBI
Rnor_6.0626,587,192 - 26,600,265 (+)NCBI
Rnor_5.0636,403,896 - 36,416,645 (+)NCBI
RGSC_v3.4625,200,452 - 25,214,909 (+)RGD
Celera624,714,225 - 24,727,365 (+)RGD
Sequence:
RefSeq Acc Id: XM_039112437   ⟹   XP_038968365
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8630,941,693 - 30,956,389 (+)NCBI
mRatBN7.2625,222,983 - 25,236,241 (+)NCBI
RefSeq Acc Id: XM_039112438   ⟹   XP_038968366
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8630,941,693 - 30,956,389 (+)NCBI
mRatBN7.2625,222,983 - 25,236,241 (+)NCBI
RefSeq Acc Id: XM_039112439   ⟹   XP_038968367
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8630,943,358 - 30,956,389 (+)NCBI
mRatBN7.2625,231,067 - 25,236,241 (+)NCBI
RefSeq Acc Id: XM_039112440   ⟹   XP_038968368
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8630,941,699 - 30,956,389 (+)NCBI
mRatBN7.2625,221,668 - 25,236,241 (+)NCBI
RefSeq Acc Id: XM_039112441   ⟹   XP_038968369
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8630,941,698 - 30,956,389 (+)NCBI
mRatBN7.2625,221,668 - 25,236,241 (+)NCBI
RefSeq Acc Id: XM_039112443   ⟹   XP_038968371
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8630,941,698 - 30,956,389 (+)NCBI
mRatBN7.2625,222,983 - 25,236,241 (+)NCBI
RefSeq Acc Id: XM_039112444   ⟹   XP_038968372
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8630,941,693 - 30,956,389 (+)NCBI
mRatBN7.2625,221,668 - 25,236,241 (+)NCBI
RefSeq Acc Id: XM_039112445   ⟹   XP_038968373
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8630,941,693 - 30,956,389 (+)NCBI
mRatBN7.2625,222,983 - 25,236,241 (+)NCBI
RefSeq Acc Id: XM_063262038   ⟹   XP_063118108
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8630,941,693 - 30,956,389 (+)NCBI
RefSeq Acc Id: XM_063262039   ⟹   XP_063118109
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8630,941,694 - 30,956,389 (+)NCBI
RefSeq Acc Id: XM_063262040   ⟹   XP_063118110
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8630,941,694 - 30,956,389 (+)NCBI
RefSeq Acc Id: XM_063262041   ⟹   XP_063118111
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8630,941,699 - 30,956,389 (+)NCBI
RefSeq Acc Id: XM_063262042   ⟹   XP_063118112
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8630,941,693 - 30,956,389 (+)NCBI
RefSeq Acc Id: XM_063262043   ⟹   XP_063118113
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8630,941,699 - 30,956,389 (+)NCBI
RefSeq Acc Id: NP_001091710   ⟸   NM_001098240
- UniProtKB: Q5BK62 (UniProtKB/Swiss-Prot),   A6HA73 (UniProtKB/TrEMBL),   A0A8I6ADY6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000037647   ⟸   ENSRNOT00000034207
RefSeq Acc Id: XP_038968369   ⟸   XM_039112441
- Peptide Label: isoform X4
- UniProtKB: Q5BK62 (UniProtKB/Swiss-Prot),   A6HA73 (UniProtKB/TrEMBL),   A0A8I6ADY6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968368   ⟸   XM_039112440
- Peptide Label: isoform X4
- UniProtKB: Q5BK62 (UniProtKB/Swiss-Prot),   A6HA73 (UniProtKB/TrEMBL),   A0A8I6ADY6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968372   ⟸   XM_039112444
- Peptide Label: isoform X5
- UniProtKB: A0A8I6GJS1 (UniProtKB/TrEMBL),   A0A8I6ADY6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968365   ⟸   XM_039112437
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038968366   ⟸   XM_039112438
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038968371   ⟸   XM_039112443
- Peptide Label: isoform X4
- UniProtKB: Q5BK62 (UniProtKB/Swiss-Prot),   A6HA73 (UniProtKB/TrEMBL),   A0A8I6ADY6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968373   ⟸   XM_039112445
- Peptide Label: isoform X5
- UniProtKB: A0A8I6GJS1 (UniProtKB/TrEMBL),   A0A8I6ADY6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968367   ⟸   XM_039112439
- Peptide Label: isoform X3
- UniProtKB: A0A8I6ADY6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000092589   ⟸   ENSRNOT00000102606
Ensembl Acc Id: ENSRNOP00000091585   ⟸   ENSRNOT00000099208
Ensembl Acc Id: ENSRNOP00000079234   ⟸   ENSRNOT00000095043
RefSeq Acc Id: XP_063118108   ⟸   XM_063262038
- Peptide Label: isoform X5
- UniProtKB: A0A8I6GJS1 (UniProtKB/TrEMBL),   A0A8I6ADY6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063118112   ⟸   XM_063262042
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063118110   ⟸   XM_063262040
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063118109   ⟸   XM_063262039
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063118113   ⟸   XM_063262043
- Peptide Label: isoform X9
RefSeq Acc Id: XP_063118111   ⟸   XM_063262041
- Peptide Label: isoform X7
- UniProtKB: A0A8I6ADY6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000111931   ⟸   ENSRNOT00000151554

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5BK62-F1-model_v2 AlphaFold Q5BK62 1-176 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694445
Promoter ID:EPDNEW_R4969
Type:single initiation site
Name:Mpv17_1
Description:MpV17 mitochondrial inner membrane protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0626,587,428 - 26,587,488EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310512 AgrOrtholog
BioCyc Gene G2FUF-38347 BioCyc
Ensembl Genes ENSRNOG00000049430 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000034207 ENTREZGENE
  ENSRNOT00000102606 ENTREZGENE
IMAGE_CLONE IMAGE:7373705 IMAGE-MGC_LOAD
InterPro Mpv17_PMP22 UniProtKB/Swiss-Prot
KEGG Report rno:360463 UniProtKB/Swiss-Prot
MGC_CLONE MGC:108867 IMAGE-MGC_LOAD
NCBI Gene 360463 ENTREZGENE
PANTHER PROTEIN MPV17 UniProtKB/Swiss-Prot
  PTHR11266 UniProtKB/Swiss-Prot
Pfam Mpv17_PMP22 UniProtKB/Swiss-Prot
PhenoGen Mpv17 PhenoGen
RatGTEx ENSRNOG00000049430 RatGTEx
UniProt A0A8I5ZME0_RAT UniProtKB/TrEMBL
  A0A8I6ADY6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GJS1 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LLU8_RAT UniProtKB/TrEMBL
  A6HA73 ENTREZGENE, UniProtKB/TrEMBL
  F1LNG8_RAT UniProtKB/TrEMBL
  MPV17_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-08-27 Mpv17  mitochondrial inner membrane protein MPV17  Mpv17  MpV17 mitochondrial inner membrane protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-08-29 Mpv17  MpV17 mitochondrial inner membrane protein  Mpv17l  MPV17 mitochondrial membrane protein-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-04-23 Mpv17l  MPV17 mitochondrial membrane protein-like  Mpv17l  Mpv17 transgene, kidney disease mutant-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-11-11 Mpv17l  Mpv17 transgene, kidney disease mutant-like  Mpv17l  MPV17 mitochondrial membrane protein-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-25 Mpv17l  MPV17 mitochondrial membrane protein-like  Mpv17l  Mpv17 transgene, kidney disease mutant-like   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Mpv17l  Mpv17 transgene, kidney disease mutant-like   Mpv17l_predicted  Mpv17 transgene, kidney disease mutant-like (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Mpv17l_predicted  Mpv17 transgene, kidney disease mutant-like (predicted)      Symbol and Name status set to approved 70820 APPROVED