Tox (thymocyte selection-associated high mobility group box) - Rat Genome Database

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Gene: Tox (thymocyte selection-associated high mobility group box) Rattus norvegicus
Analyze
Symbol: Tox
Name: thymocyte selection-associated high mobility group box
RGD ID: 1310455
Description: Predicted to enable chromatin DNA binding activity. Predicted to be involved in several processes, including cerebral cortex neuron differentiation; lymphocyte differentiation; and regulation of positive thymic T cell selection. Predicted to act upstream of or within hematopoietic or lymphoid organ development; lymphocyte differentiation; and positive regulation of natural killer cell differentiation. Predicted to be active in nucleus. Orthologous to human TOX (thymocyte selection associated high mobility group box); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC362481; thymocyte selection-associated high mobility group box protein TOX; thymocyte selection-associated HMG box; thymocyte selection-associated HMG box gene
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8524,672,487 - 24,968,754 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl524,672,487 - 24,968,754 (-)EnsemblGRCr8
mRatBN7.2519,874,994 - 20,171,272 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl519,874,467 - 20,171,272 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx522,100,634 - 22,397,195 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0523,694,988 - 23,991,309 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0523,475,253 - 23,771,571 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0519,892,698 - 20,189,721 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl519,892,698 - 20,189,721 (-)Ensemblrn6Rnor6.0
Rnor_5.0524,669,152 - 24,965,951 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4520,304,971 - 20,601,406 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera519,165,384 - 19,461,532 (-)NCBICelera
RGSC_v3.1520,306,623 - 20,780,036 (-)NCBI
Cytogenetic Map5q12NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
amphetamine  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
Butylbenzyl phthalate  (ISO)
carbon nanotube  (ISO)
choline  (ISO)
chromium(6+)  (ISO)
cobalt dichloride  (ISO)
cyclosporin A  (ISO)
dibutyl phthalate  (ISO)
dichloroacetic acid  (ISO)
diclofenac  (EXP)
diuron  (EXP)
dorsomorphin  (ISO)
entinostat  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
folic acid  (ISO)
fulvestrant  (ISO)
gentamycin  (EXP)
glycidol  (EXP)
L-methionine  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
melphalan  (ISO)
mercury dibromide  (ISO)
methylisothiazolinone  (ISO)
nickel sulfate  (ISO)
panobinostat  (ISO)
paracetamol  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenylephrine  (EXP)
pirinixic acid  (ISO)
potassium chromate  (ISO)
SB 431542  (ISO)
senecionine  (ISO)
sodium arsenite  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
testosterone  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (EXP)
titanium dioxide  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (IBA,IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11850626   PMID:15078895   PMID:18195075   PMID:20818394   PMID:21126536   PMID:25527292  


Genomics

Comparative Map Data
Tox
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8524,672,487 - 24,968,754 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl524,672,487 - 24,968,754 (-)EnsemblGRCr8
mRatBN7.2519,874,994 - 20,171,272 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl519,874,467 - 20,171,272 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx522,100,634 - 22,397,195 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0523,694,988 - 23,991,309 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0523,475,253 - 23,771,571 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0519,892,698 - 20,189,721 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl519,892,698 - 20,189,721 (-)Ensemblrn6Rnor6.0
Rnor_5.0524,669,152 - 24,965,951 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4520,304,971 - 20,601,406 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera519,165,384 - 19,461,532 (-)NCBICelera
RGSC_v3.1520,306,623 - 20,780,036 (-)NCBI
Cytogenetic Map5q12NCBI
TOX
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38858,805,412 - 59,119,147 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl858,805,412 - 59,119,279 (-)Ensemblhg38GRCh38
GRCh37859,717,971 - 60,031,706 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36859,880,531 - 60,194,321 (-)NCBIBuild 36Build 36hg18NCBI36
Celera855,710,971 - 56,023,242 (-)NCBICelera
Cytogenetic Map8q12.1NCBI
HuRef855,205,353 - 55,519,346 (-)NCBIHuRef
CHM1_1859,770,293 - 60,083,901 (-)NCBICHM1_1
T2T-CHM13v2.0859,226,626 - 59,540,470 (-)NCBIT2T-CHM13v2.0
Tox
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3946,686,353 - 6,991,557 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl46,686,353 - 6,991,557 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm3846,686,353 - 6,991,557 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl46,686,353 - 6,991,557 (-)Ensemblmm10GRCm38
MGSCv3746,614,533 - 6,917,870 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3646,614,605 - 6,917,870 (-)NCBIMGSCv36mm8
Celera46,590,011 - 6,896,370 (-)NCBICelera
Cytogenetic Map4A1NCBI
cM Map43.04NCBI
Tox
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544419,453,783 - 19,795,167 (+)Ensembl
ChiLan1.0NW_00495544419,453,789 - 19,796,419 (+)NCBIChiLan1.0ChiLan1.0
TOX
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2774,489,654 - 74,795,117 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1850,142,418 - 50,449,169 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0855,246,933 - 55,553,839 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1856,913,312 - 57,219,640 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl856,922,773 - 57,219,410 (-)EnsemblpanPan2panpan1.1
TOX
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1299,542,471 - 9,841,759 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl299,544,561 - 9,842,034 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha299,854,051 - 10,152,715 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0299,627,150 - 9,926,763 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl299,626,943 - 9,926,757 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1299,624,865 - 9,923,979 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0299,750,678 - 10,048,990 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02910,030,303 - 10,329,882 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Tox
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530360,638,151 - 60,938,267 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649613,847,210 - 14,147,886 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493649613,847,210 - 14,146,110 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TOX
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl473,810,290 - 74,115,151 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1473,810,180 - 74,115,352 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2480,756,768 - 80,906,112 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TOX
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1854,777,490 - 55,086,819 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl854,776,015 - 54,927,091 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603986,630,447 - 86,940,047 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tox
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474432,865,720 - 33,218,643 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474432,865,781 - 33,218,453 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Tox
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11135,357,618 - 135,508,703 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Tox
3983 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:179
Count of miRNA genes:123
Interacting mature miRNAs:150
Transcripts:ENSRNOT00000014661
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2293666Bmd38Bone mineral density QTL 384.4femur size trait (VT:1000369)femoral neck cortical cross-sectional area (CMO:0001702)51373115343590997Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)5692228281330203Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)52367149379046465Rat
1300117Hrtrt8Heart rate QTL 83.49heart pumping trait (VT:2000009)heart rate (CMO:0000002)5862723052665523Rat
7394712Emca13Estrogen-induced mammary cancer QTL 13mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)51460607859606078Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)51757663362576633Rat
1578774Tcas8Tongue tumor susceptibility QTL 83.47tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)51570745160707451Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906491770353Rat
2312562Pur18Proteinuria QTL 182.60.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)5692228237468560Rat
8662454Vetf3Vascular elastic tissue fragility QTL 327.4artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)5706553574335773Rat
1641903Alcrsp3Alcohol response QTL 3response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)51748608062486080Rat
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906487027358Rat
631827Alc4Alcohol consumption QTL 43.5consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)51297048025683802Rat
2303577Gluco47Glucose level QTL 473blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51652001961520019Rat
1641922Alcrsp8Alcohol response QTL 8alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)51748608062486080Rat
2313085Bss59Bone structure and strength QTL 592.90.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)5862723053627230Rat
1600358Mamtr5Mammary tumor resistance QTL 5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)52367149368671493Rat

Markers in Region
AU046800  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8524,759,863 - 24,760,072 (+)Marker Load Pipeline
mRatBN7.2519,962,372 - 19,962,581 (+)MAPPERmRatBN7.2
Rnor_6.0519,980,210 - 19,980,418NCBIRnor6.0
Rnor_5.0524,756,792 - 24,757,000UniSTSRnor5.0
RGSC_v3.4520,392,613 - 20,392,821UniSTSRGSC3.4
Celera519,252,879 - 19,253,087UniSTS
Cytogenetic Map5q13UniSTS
RH139499  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2519,875,413 - 19,875,619 (+)MAPPERmRatBN7.2
Rnor_6.0519,893,118 - 19,893,323NCBIRnor6.0
Rnor_5.0524,669,572 - 24,669,777UniSTSRnor5.0
RGSC_v3.4520,305,391 - 20,305,596UniSTSRGSC3.4
Celera519,165,804 - 19,166,009UniSTS
RH 3.4 Map587.0UniSTS
Cytogenetic Map5q13UniSTS
RH140334  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2519,875,409 - 19,875,551 (+)MAPPERmRatBN7.2
Rnor_6.0519,893,114 - 19,893,255NCBIRnor6.0
Rnor_5.0524,669,568 - 24,669,709UniSTSRnor5.0
RGSC_v3.4520,305,387 - 20,305,528UniSTSRGSC3.4
Celera519,165,800 - 19,165,941UniSTS
Cytogenetic Map5q13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 161 90 89 58 92 58 6 355 192 11 140 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000014661   ⟹   ENSRNOP00000014661
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl524,672,487 - 24,968,754 (-)Ensembl
mRatBN7.2 Ensembl519,874,994 - 20,171,272 (-)Ensembl
Rnor_6.0 Ensembl519,892,698 - 20,189,721 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000095284   ⟹   ENSRNOP00000087610
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl524,672,487 - 24,822,712 (-)Ensembl
mRatBN7.2 Ensembl519,874,467 - 20,006,812 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000099543   ⟹   ENSRNOP00000097335
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl524,672,487 - 24,827,281 (-)Ensembl
mRatBN7.2 Ensembl519,875,308 - 20,029,738 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000102072   ⟹   ENSRNOP00000098002
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl524,672,487 - 24,968,113 (-)Ensembl
mRatBN7.2 Ensembl519,876,217 - 20,170,516 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000133851   ⟹   ENSRNOP00000112043
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl524,672,487 - 24,964,147 (-)Ensembl
RefSeq Acc Id: NM_001108654   ⟹   NP_001102124
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8524,672,487 - 24,968,754 (-)NCBI
mRatBN7.2519,874,994 - 20,171,272 (-)NCBI
Rnor_6.0519,892,698 - 20,189,721 (-)NCBI
Rnor_5.0524,669,152 - 24,965,951 (-)NCBI
RGSC_v3.4520,304,971 - 20,601,406 (-)RGD
Celera519,165,384 - 19,461,532 (-)RGD
Sequence:
RefSeq Acc Id: XM_006237844   ⟹   XP_006237906
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8524,672,675 - 24,968,073 (-)NCBI
mRatBN7.2519,875,182 - 20,170,935 (-)NCBI
Rnor_6.0519,892,878 - 20,189,018 (-)NCBI
Rnor_5.0524,669,152 - 24,965,951 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017593467   ⟹   XP_017448956
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8524,672,675 - 24,968,006 (-)NCBI
mRatBN7.2519,875,182 - 20,170,562 (-)NCBI
Rnor_6.0519,892,878 - 20,189,442 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039110215   ⟹   XP_038966143
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8524,672,675 - 24,967,995 (-)NCBI
mRatBN7.2519,875,182 - 20,170,498 (-)NCBI
RefSeq Acc Id: XM_063287898   ⟹   XP_063143968
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8524,672,675 - 24,827,486 (-)NCBI
RefSeq Acc Id: NP_001102124   ⟸   NM_001108654
- UniProtKB: D4A1U5 (UniProtKB/TrEMBL),   A6JFP6 (UniProtKB/TrEMBL),   A0A8I6B6M0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006237906   ⟸   XM_006237844
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017448956   ⟸   XM_017593467
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSRNOP00000014661   ⟸   ENSRNOT00000014661
RefSeq Acc Id: XP_038966143   ⟸   XM_039110215
- Peptide Label: isoform X2
Ensembl Acc Id: ENSRNOP00000097335   ⟸   ENSRNOT00000099543
Ensembl Acc Id: ENSRNOP00000087610   ⟸   ENSRNOT00000095284
Ensembl Acc Id: ENSRNOP00000098002   ⟸   ENSRNOT00000102072
RefSeq Acc Id: XP_063143968   ⟸   XM_063287898
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AU85 (UniProtKB/TrEMBL),   A0A8I6B6M0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000112043   ⟸   ENSRNOT00000133851
Protein Domains
HMG box

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A1U5-F1-model_v2 AlphaFold D4A1U5 1-525 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310455 AgrOrtholog
BioCyc Gene G2FUF-42066 BioCyc
Ensembl Genes ENSRNOG00000010777 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000014661 ENTREZGENE
  ENSRNOT00000014661.5 UniProtKB/TrEMBL
  ENSRNOT00000095284.2 UniProtKB/TrEMBL
  ENSRNOT00000099543 ENTREZGENE
  ENSRNOT00000099543.2 UniProtKB/TrEMBL
  ENSRNOT00000102072 ENTREZGENE
  ENSRNOT00000102072.2 UniProtKB/TrEMBL
  ENSRNOT00000133851 ENTREZGENE
  ENSRNOT00000133851.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.30.10 UniProtKB/TrEMBL
InterPro HMG_box_dom_sf UniProtKB/TrEMBL
  HMG_superfamily UniProtKB/TrEMBL
  TOX_HMG-box_domain UniProtKB/TrEMBL
KEGG Report rno:362481 UniProtKB/TrEMBL
NCBI Gene 362481 ENTREZGENE
PANTHER AGAP000281-PA UniProtKB/TrEMBL
  THYMOCYTE SELECTION-ASSOCIATED HIGH MOBILITY GROUP BOX PROTEIN TOX UniProtKB/TrEMBL
Pfam HMG_box UniProtKB/TrEMBL
PhenoGen Tox PhenoGen
PRINTS HIGHMOBLTY12 UniProtKB/TrEMBL
PROSITE HMG_BOX_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000010777 RatGTEx
SMART HMG UniProtKB/TrEMBL
Superfamily-SCOP HMG-box UniProtKB/TrEMBL
UniProt A0A8I6AU85 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6B6M0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GG62_RAT UniProtKB/TrEMBL
  A0ABK0LZS7_RAT UniProtKB/TrEMBL
  A6JFP6 ENTREZGENE, UniProtKB/TrEMBL
  D4A1U5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-19 Tox  thymocyte selection-associated high mobility group box  Tox_predicted  thymocyte selection-associated HMG box gene (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-12 Tox_predicted  thymocyte selection-associated HMG box gene (predicted)      Symbol and Name status set to approved 70820 APPROVED