Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of NIPSNAP1 mRNA] | CTD | PMID:31150632 | 1,2-dimethylhydrazine | decreases expression | ISO | Nipsnap1 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of NIPSNAP1 mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | decreases expression | EXP | | 6480464 | Ethinyl Estradiol results in decreased expression of NIPSNAP1 mRNA | CTD | PMID:17557909 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Nipsnap1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to NIPSNAP1 promoter] | CTD | PMID:19654925 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of NIPSNAP1 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of NIPSNAP1 mRNA | CTD | PMID:21215274 | 2,4,6-trinitrotoluene | affects expression | EXP | | 6480464 | Trinitrotoluene affects the expression of NIPSNAP1 mRNA | CTD | PMID:21346803 | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 4-dinitrotoluene affects the expression of NIPSNAP1 mRNA | CTD | PMID:21346803 | 3,4-methylenedioxymethamphetamine | increases expression | ISO | Nipsnap1 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of NIPSNAP1 mRNA | CTD | PMID:26251327 | 4,4'-diaminodiphenylmethane | decreases expression | EXP | | 6480464 | 4 and 4'-diaminodiphenylmethane results in decreased expression of NIPSNAP1 mRNA | CTD | PMID:30723492 | 4-hydroxyphenyl retinamide | increases expression | ISO | Nipsnap1 (Mus musculus) | 6480464 | Fenretinide results in increased expression of NIPSNAP1 mRNA | CTD | PMID:28973697 | 5-aza-2'-deoxycytidine | increases expression | ISO | NIPSNAP1 (Homo sapiens) | 6480464 | Decitabine results in increased expression of NIPSNAP1 mRNA | CTD | PMID:17908484 | 5-aza-2'-deoxycytidine | affects expression | ISO | NIPSNAP1 (Homo sapiens) | 6480464 | Decitabine affects the expression of NIPSNAP1 mRNA | CTD | PMID:17145863 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of NIPSNAP1 mRNA | CTD | PMID:30047161 | acetamide | decreases expression | EXP | | 6480464 | acetamide results in decreased expression of NIPSNAP1 mRNA | CTD | PMID:31881176 | acrylamide | decreases expression | ISO | NIPSNAP1 (Homo sapiens) | 6480464 | Acrylamide results in decreased expression of NIPSNAP1 mRNA | CTD | PMID:32763439 | aflatoxin B1 | affects expression | ISO | NIPSNAP1 (Homo sapiens) | 6480464 | Aflatoxin B1 affects the expression of NIPSNAP1 protein | CTD | PMID:20106945 | all-trans-retinoic acid | decreases expression | ISO | NIPSNAP1 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of NIPSNAP1 mRNA | CTD | PMID:21934132 | all-trans-retinoic acid | increases expression | ISO | NIPSNAP1 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of NIPSNAP1 mRNA | CTD | PMID:15498508 | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of NIPSNAP1 mRNA | CTD | PMID:30047161 | aristolochic acid A | decreases expression | ISO | NIPSNAP1 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of NIPSNAP1 mRNA | CTD | PMID:33212167 | arsane | increases methylation | ISO | NIPSNAP1 (Homo sapiens) | 6480464 | Arsenic results in increased methylation of NIPSNAP1 promoter | CTD | PMID:21291286 | arsenic atom | increases methylation | ISO | NIPSNAP1 (Homo sapiens) | 6480464 | Arsenic results in increased methylation of NIPSNAP1 promoter | CTD | PMID:21291286 | arsenite(3-) | multiple interactions | ISO | NIPSNAP1 (Homo sapiens) | 6480464 | arsenite promotes the reaction [G3BP1 protein binds to NIPSNAP1 mRNA] | CTD | PMID:32406909 | benzo[a]pyrene | affects methylation | ISO | NIPSNAP1 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of NIPSNAP1 promoter | CTD | PMID:27901495 | benzo[a]pyrene | decreases expression | ISO | NIPSNAP1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of NIPSNAP1 mRNA | CTD | PMID:32234424 | bisphenol A | decreases expression | ISO | Nipsnap1 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of NIPSNAP1 mRNA | CTD | PMID:26063408 | bisphenol A | increases expression | ISO | NIPSNAP1 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of NIPSNAP1 protein | CTD | PMID:37567409 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of NIPSNAP1 mRNA and bisphenol A results in decreased expression of NIPSNAP1 protein | CTD | PMID:32145629 and PMID:34947998 | bisphenol A | affects expression | ISO | NIPSNAP1 (Homo sapiens) | 6480464 | bisphenol A affects the expression of NIPSNAP1 mRNA | CTD | PMID:30903817 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of NIPSNAP1 mRNA | CTD | PMID:25181051 | Bisphenol B | increases expression | ISO | NIPSNAP1 (Homo sapiens) | 6480464 | bisphenol B results in increased expression of NIPSNAP1 protein | CTD | PMID:34186270 | bortezomib | decreases expression | ISO | NIPSNAP1 (Homo sapiens) | 6480464 | Bortezomib results in decreased expression of NIPSNAP1 mRNA | CTD | PMID:20977926 | Brodifacoum | increases expression | EXP | | 6480464 | bromfenacoum results in increased expression of NIPSNAP1 protein | CTD | PMID:28903499 | cadmium dichloride | increases expression | ISO | NIPSNAP1 (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of NIPSNAP1 protein | CTD | PMID:24527689 | CGP 52608 | multiple interactions | ISO | NIPSNAP1 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to NIPSNAP1 gene] | CTD | PMID:28238834 | chlorpyrifos | increases expression | ISO | Nipsnap1 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of NIPSNAP1 mRNA | CTD | PMID:37019170 | cisplatin | multiple interactions | ISO | NIPSNAP1 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of NIPSNAP1 mRNA | CTD | PMID:27392435 | clotrimazole | decreases expression | EXP | | 6480464 | Clotrimazole results in decreased expression of NIPSNAP1 mRNA | CTD | PMID:30047161 | cobalt dichloride | decreases expression | ISO | NIPSNAP1 (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of NIPSNAP1 mRNA | CTD | PMID:19320972 and PMID:19376846 | copper atom | multiple interactions | ISO | NIPSNAP1 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of NIPSNAP1 mRNA | CTD | PMID:20971185 | copper(0) | multiple interactions | ISO | NIPSNAP1 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of NIPSNAP1 mRNA | CTD | PMID:20971185 | copper(II) sulfate | decreases expression | ISO | NIPSNAP1 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of NIPSNAP1 mRNA | CTD | PMID:19549813 | cyclosporin A | decreases expression | ISO | NIPSNAP1 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of NIPSNAP1 mRNA | CTD | PMID:20106945 and PMID:25562108 | dibenzofurans | increases expression | ISO | Nipsnap1 (Mus musculus) | 6480464 | Dibenzofurans results in increased expression of NIPSNAP1 mRNA | CTD | PMID:34254344 | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of NIPSNAP1 mRNA | CTD | PMID:21266533 | dibutyl phthalate | decreases expression | ISO | Nipsnap1 (Mus musculus) | 6480464 | Dibutyl Phthalate results in decreased expression of NIPSNAP1 mRNA | CTD | PMID:17361019 and PMID:21266533 | dorsomorphin | multiple interactions | ISO | NIPSNAP1 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | doxorubicin | decreases expression | ISO | NIPSNAP1 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of NIPSNAP1 mRNA | CTD | PMID:29803840 | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of NIPSNAP1 mRNA | CTD | PMID:29391264 | epoxiconazole | decreases expression | ISO | Nipsnap1 (Mus musculus) | 6480464 | epoxiconazole results in decreased expression of NIPSNAP1 mRNA | CTD | PMID:35436446 | ethanol | affects splicing | ISO | Nipsnap1 (Mus musculus) | 6480464 | Ethanol affects the splicing of NIPSNAP1 mRNA | CTD | PMID:30319688 | ethanol | increases expression | ISO | Nipsnap1 (Mus musculus) | 6480464 | Ethanol results in increased expression of NIPSNAP1 mRNA | CTD | PMID:30319688 | fipronil | increases expression | EXP | | 6480464 | fipronil results in increased expression of NIPSNAP1 mRNA | CTD | PMID:34044035 | flutamide | decreases expression | EXP | | 6480464 | Flutamide results in decreased expression of NIPSNAP1 mRNA | CTD | PMID:24793618 | ivermectin | decreases expression | ISO | NIPSNAP1 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of NIPSNAP1 protein | CTD | PMID:32959892 | mercury dichloride | decreases expression | ISO | NIPSNAP1 (Homo sapiens) | 6480464 | Mercuric Chloride results in decreased expression of NIPSNAP1 mRNA | CTD | PMID:27188386 | methapyrilene | decreases expression | EXP | | 6480464 | Methapyrilene results in decreased expression of NIPSNAP1 mRNA | CTD | PMID:30467583 | methimazole | decreases expression | EXP | | 6480464 | Methimazole results in decreased expression of NIPSNAP1 mRNA | CTD | PMID:30047161 | N-methyl-4-phenylpyridinium | decreases expression | ISO | NIPSNAP1 (Homo sapiens) | 6480464 | 1-Methyl-4-phenylpyridinium results in decreased expression of NIPSNAP1 protein | CTD | PMID:24806433 | p-toluidine | increases expression | EXP | | 6480464 | 4-toluidine results in increased expression of NIPSNAP1 mRNA | CTD | PMID:27638505 | paracetamol | affects expression | ISO | Nipsnap1 (Mus musculus) | 6480464 | Acetaminophen affects the expression of NIPSNAP1 mRNA | CTD | PMID:17562736 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of NIPSNAP1 mRNA | CTD | PMID:33387578 | paracetamol | decreases expression | ISO | NIPSNAP1 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of NIPSNAP1 mRNA | CTD | PMID:25704631 and PMID:29067470 | perfluorooctanoic acid | increases expression | ISO | NIPSNAP1 (Homo sapiens) | 6480464 | perfluorooctanoic acid results in increased expression of NIPSNAP1 protein | CTD | PMID:26879310 | propiconazole | decreases expression | ISO | Nipsnap1 (Mus musculus) | 6480464 | propiconazole results in decreased expression of NIPSNAP1 mRNA | CTD | PMID:21278054 | resveratrol | multiple interactions | ISO | NIPSNAP1 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of NIPSNAP1 mRNA | CTD | PMID:23557933 | SB 431542 | multiple interactions | ISO | NIPSNAP1 (Homo sapiens) | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 and PMID:37664457 | sodium arsenite | decreases expression | ISO | Nipsnap1 (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of NIPSNAP1 mRNA | CTD | PMID:37682722 | Soman | decreases expression | EXP | | 6480464 | Soman results in decreased expression of NIPSNAP1 mRNA | CTD | PMID:19281266 | sulfadimethoxine | decreases expression | EXP | | 6480464 | Sulfadimethoxine results in decreased expression of NIPSNAP1 mRNA | CTD | PMID:30047161 | sunitinib | decreases expression | ISO | NIPSNAP1 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of NIPSNAP1 mRNA | CTD | PMID:31533062 | tamibarotene | increases expression | ISO | NIPSNAP1 (Homo sapiens) | 6480464 | tamibarotene results in increased expression of NIPSNAP1 mRNA | CTD | PMID:15498508 | tetrachloromethane | decreases expression | ISO | Nipsnap1 (Mus musculus) | 6480464 | Carbon Tetrachloride results in decreased expression of NIPSNAP1 mRNA | CTD | PMID:27339419 and PMID:31919559 | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of NIPSNAP1 mRNA] | CTD | PMID:31150632 | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of NIPSNAP1 mRNA | CTD | PMID:31150632 | tetrahydropalmatine | increases expression | ISO | NIPSNAP1 (Homo sapiens) | 6480464 | tetrahydropalmatine results in increased expression of NIPSNAP1 protein | CTD | PMID:20109541 | thapsigargin | decreases expression | ISO | NIPSNAP1 (Homo sapiens) | 6480464 | Thapsigargin results in decreased expression of NIPSNAP1 mRNA | CTD | PMID:22378314 | thimerosal | decreases expression | ISO | NIPSNAP1 (Homo sapiens) | 6480464 | Thimerosal results in decreased expression of NIPSNAP1 mRNA | CTD | PMID:27188386 | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of NIPSNAP1 mRNA | CTD | PMID:34492290 | tolcapone | affects binding | EXP | | 6480464 | tolcapone binds to NIPSNAP1 protein | CTD | PMID:19783845 | trichostatin A | decreases expression | ISO | NIPSNAP1 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of NIPSNAP1 mRNA | CTD | PMID:24935251 and PMID:26272509 | trichostatin A | multiple interactions | ISO | NIPSNAP1 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of NIPSNAP1 mRNA | CTD | PMID:27188386 | triptonide | increases expression | ISO | Nipsnap1 (Mus musculus) | 6480464 | triptonide results in increased expression of NIPSNAP1 mRNA | CTD | PMID:33045310 | tunicamycin | decreases expression | ISO | NIPSNAP1 (Homo sapiens) | 6480464 | Tunicamycin results in decreased expression of NIPSNAP1 mRNA | CTD | PMID:22378314 | urethane | decreases expression | ISO | NIPSNAP1 (Homo sapiens) | 6480464 | Urethane results in decreased expression of NIPSNAP1 mRNA | CTD | PMID:28818685 | valdecoxib | decreases expression | EXP | | 6480464 | valdecoxib results in decreased expression of NIPSNAP1 mRNA | CTD | PMID:24136188 | valproic acid | affects expression | ISO | Nipsnap1 (Mus musculus) | 6480464 | Valproic Acid affects the expression of NIPSNAP1 mRNA | CTD | PMID:17292431 | valproic acid | decreases methylation | ISO | NIPSNAP1 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of NIPSNAP1 gene | CTD | PMID:29501571 | valproic acid | multiple interactions | ISO | NIPSNAP1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of NIPSNAP1 mRNA | CTD | PMID:27188386 | valproic acid | decreases expression | ISO | NIPSNAP1 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of NIPSNAP1 mRNA | CTD | PMID:23179753 more ... | valproic acid | affects expression | ISO | NIPSNAP1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of NIPSNAP1 mRNA | CTD | PMID:25979313 | vancomycin | increases expression | ISO | Nipsnap1 (Mus musculus) | 6480464 | Vancomycin results in increased expression of NIPSNAP1 mRNA | CTD | PMID:18930951 | vorinostat | decreases expression | ISO | NIPSNAP1 (Homo sapiens) | 6480464 | vorinostat results in decreased expression of NIPSNAP1 mRNA | CTD | PMID:27188386 | |