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Gene: Snx18 (sorting nexin 18) Rattus norvegicus

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Symbol:

Snx18

Name:

sorting nexin 18

RGD ID:

1310367

Description:

Predicted to enable phosphatidylinositol-4,5-bisphosphate binding activity. Predicted to be involved in several processes, including cytoskeleton-dependent cytokinesis; plasma membrane tubulation; and positive regulation of autophagosome assembly. Predicted to be located in several cellular components, including cytoplasmic side of plasma membrane; extracellular exosome; and growth cone. Predicted to be active in plasma membrane and recycling endosome membrane. Orthologous to human SNX18 (sorting nexin 18); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC310097; Snag1; sorting nexin associated golgi protein 1; sorting nexin-18

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SNX18 (sorting nexin 18)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Snx18 (sorting nexin 18)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Snx18 (sorting nexin 18)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SNX18 (sorting nexin 18)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SNX18 (sorting nexin 18)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Snx18 (sorting nexin 18)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SNX18 (sorting nexin 18)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SNX18 (sorting nexin 18)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Snx18 (sorting nexin 18)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Snx18 (sorting nexin 18)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	FEZF2 (FEZ family zinc finger 2)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	SNX18 (sorting nexin 18)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Snx18 (sorting nexin 18)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	snx18a (sorting nexin 18a)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	snx18b (sorting nexin 18b)	Alliance	DIOPT (OrthoFinder\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	lst-4	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	lst-4	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	SH3PX1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	SH3PX1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	snx18	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	snx18	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	46,965,498 - 46,991,516 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	2	46,965,498 - 46,991,516 (-)	Ensembl				GRCr8
mRatBN7.2	2	45,232,325 - 45,258,345 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	45,232,325 - 45,258,345 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	2	52,343,993 - 52,369,979 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	50,402,361 - 50,428,348 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	45,274,943 - 45,301,291 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	45,454,782 - 45,480,798 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	45,454,782 - 45,480,798 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	2	64,486,855 - 64,512,619 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	2	45,014,383 - 45,040,586 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	2	41,000,711 - 41,026,746 (-)	NCBI		Celera
RGSC_v3.1	2	44,943,876 - 45,006,230 (-)	NCBI
Cytogenetic Map	2	q14	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Chemical and Drug Induced Liver Injury (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4,6-tribromophenol (ISO)

3,3',5,5'-tetrabromobisphenol A (ISO)

acrolein (ISO)

aflatoxin B1 (ISO)

alpha-pinene (ISO)

amiodarone (ISO)

amphetamine (EXP)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol AF (ISO)

Butylbenzyl phthalate (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

calcitriol (ISO)

chlorpyrifos (ISO)

Cuprizon (EXP)

decabromodiphenyl ether (ISO)

dibutyl phthalate (EXP)

dorsomorphin (ISO)

fenvalerate (EXP)

flutamide (EXP)

FR900359 (ISO)

inulin (ISO)

irinotecan (ISO)

ketoconazole (ISO)

lipopolysaccharide (ISO)

methotrexate (ISO)

methoxychlor (EXP)

oxaliplatin (EXP)

ozone (ISO)

paracetamol (EXP,ISO)

perfluorooctane-1-sulfonic acid (ISO)

phenobarbital (ISO)

phenylmercury acetate (ISO)

resveratrol (ISO)

rotenone (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

SB 431542 (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

Soman (EXP)

tetrachloromethane (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

topotecan (EXP)

trichostatin A (ISO)

tungsten (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell division (IEA)

cleavage furrow formation (IBA,IEA,ISO)

endocytosis (IBA,IEA,ISO)

endosomal transport (IBA,IEA,ISO)

mitotic cell cycle (IEA)

mitotic cytokinesis (IEA,ISO)

plasma membrane tubulation (IBA)

positive regulation of autophagosome assembly (IEA,ISO)

positive regulation of GTPase activity (ISO)

protein transport (IEA,ISO)

Cellular Component

clathrin-coated vesicle (IEA,ISO)

cytoplasmic side of plasma membrane (IEA,ISO)

cytoplasmic vesicle (IBA,IEA,ISO)

cytoplasmic vesicle membrane (IEA)

extracellular exosome (IEA,ISO)

growth cone (ISO)

neuronal cell body (ISO)

plasma membrane (IBA)

recycling endosome membrane (IEA,ISO)

Molecular Function

phosphatidylinositol binding (IBA,IEA,ISO)

phosphatidylinositol-4,5-bisphosphate binding (IEA,ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:15326289	PMID:19056867	PMID:20427313	PMID:21339182	PMID:22718350	PMID:23376485	PMID:23533145	PMID:23878278	PMID:28235806

Genomics

Comparative Map Data

Snx18
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	46,965,498 - 46,991,516 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	2	46,965,498 - 46,991,516 (-)	Ensembl				GRCr8
mRatBN7.2	2	45,232,325 - 45,258,345 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	45,232,325 - 45,258,345 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	2	52,343,993 - 52,369,979 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	50,402,361 - 50,428,348 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	45,274,943 - 45,301,291 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	45,454,782 - 45,480,798 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	45,454,782 - 45,480,798 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	2	64,486,855 - 64,512,619 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	2	45,014,383 - 45,040,586 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	2	41,000,711 - 41,026,746 (-)	NCBI		Celera
RGSC_v3.1	2	44,943,876 - 45,006,230 (-)	NCBI
Cytogenetic Map	2	q14	NCBI

SNX18
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	54,517,759 - 54,648,005 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	54,517,727 - 54,546,586 (+)	Ensembl			hg38	GRCh38
GRCh37	5	53,813,589 - 53,842,416 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	53,849,350 - 53,878,173 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	5	53,849,539 - 53,851,426	NCBI
Celera	5	50,767,064 - 50,795,890 (+)	NCBI		Celera
Cytogenetic Map	5	q11.2	NCBI
HuRef	5	50,787,437 - 50,816,259 (+)	NCBI		HuRef
CHM1_1	5	53,816,580 - 53,845,409 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	5	55,345,475 - 55,475,784 (+)	NCBI		T2T-CHM13v2.0

Snx18
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	13	113,728,715 - 113,755,100 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	13	113,728,715 - 113,755,100 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	13	113,592,179 - 113,618,564 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	13	113,592,179 - 113,618,564 (-)	Ensembl			mm10	GRCm38
MGSCv37	13	114,382,387 - 114,408,772 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	13	114,713,061 - 114,739,419 (-)	NCBI		MGSCv36	mm8
Celera	13	117,901,784 - 117,928,168 (-)	NCBI		Celera
Cytogenetic Map	13	D2.2	NCBI
cM Map	13	64.0	NCBI

Snx18
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955446	13,043,821 - 13,067,933 (-)	Ensembl
ChiLan1.0	NW_004955446	13,043,821 - 13,067,933 (-)	NCBI	ChiLan1.0	ChiLan1.0

SNX18
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	59,181,347 - 59,419,695 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	57,334,972 - 57,573,292 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	59,270,053 - 59,508,359 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	61,101,061 - 61,129,397 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	61,101,056 - 61,129,397 (-)	Ensembl			panPan2	panpan1.1

SNX18
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	4	60,803,245 - 60,945,317 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	4	60,835,783 - 60,945,828 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	4	60,569,927 - 60,710,959 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	4	61,295,275 - 61,436,640 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	4	61,302,014 - 61,436,904 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	4	61,185,900 - 61,215,498 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	4	61,201,579 - 61,342,650 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	4	61,720,198 - 61,861,418 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Snx18
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	204,025,143 - 204,201,070 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936480	13,110,928 - 13,137,361 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936480	13,108,510 - 13,137,550 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SNX18
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	16	33,776,746 - 33,847,624 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	16	33,776,964 - 33,801,391 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	16	35,846,933 - 35,859,015 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SNX18
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	4	50,782,842 - 50,810,220 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	4	50,782,929 - 50,811,253 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666082	261,616 - 288,960 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Snx18
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624759	4,850,555 - 4,879,478 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624759	4,851,014 - 4,879,365 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Snx18
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	3	183,176,070 - 183,202,331 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Snx18
182 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	729
Count of miRNA genes:	299
Interacting mature miRNAs:	403
Transcripts:	ENSRNOT00000066764
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
10755430	Coatc6	Coat color QTL 6		0.02576	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	2	13325041	58325041	Rat
7387318	Stl32	Serum triglyceride level QTL 32	3.2	0.0003	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	2	24117813	69117813	Rat
10755436	Coatc8	Coat color QTL 8		0.02431	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	2	36750344	81750344	Rat
1298074	Bp164	Blood pressure QTL 164		0.003	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	44537979	205135428	Rat
10755499	Bp389	Blood pressure QTL 389	2.61		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	20695736	231474293	Rat
1358917	Cm42	Cardiac mass QTL 42	2.82		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	27148328	206613235	Rat
9590080	Insglur4	Insulin/glucose ratio QTL 4	28.7	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	2	6152767	51152767	Rat
1300160	Hrtrt3	Heart rate QTL 3	3.62		heart pumping trait (VT:2000009)	absolute change in heart rate (CMO:0000534)	2	35614083	53462005	Rat
1579916	Bp270	Blood pressure QTL 270		0.003	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	16051883	61051883	Rat
731167	Glom4	Glomerulus QTL 4	2.4	0.0082	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	2	22038044	67038044	Rat
731166	Mamtr2	Mammary tumor resistance QTL 2		0.0001	mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	2	9623581	54623581	Rat
1358913	Cm41	Cardiac mass QTL 41	2.73		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	27148328	206613235	Rat
152025242	Bw191	Body weight QTL 191	3.62		body mass (VT:0001259)		2	40306867	124537199	Rat
1302794	Stl27	Serum triglyceride level QTL 27	4.4	0.0001	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	2	27148328	145807373	Rat
9685065	Swd6	Spike wave discharge measurement QTL 6	5.8	0.01	brain electrophysiology trait (VT:0010557)	brain spike-and-wave discharge rate (CMO:0001739)	2	40957423	50526673	Rat
9590095	Sffal3	Serum free fatty acids level QTL 3	6.78	0.001	blood free fatty acid amount (VT:0001553)	plasma free fatty acids level (CMO:0000546)	2	28889991	73889991	Rat
70174	BpQTLCluster2	Blood pressure QTL cluster 2	4.24		arterial blood pressure trait (VT:2000000)	absolute change in mean arterial blood pressure (CMO:0000533)	2	41801363	104744824	Rat
1331764	Bp205	Blood pressure QTL 205	3.476		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	14368707	59368707	Rat
1358901	Cm38	Cardiac mass QTL 38	2		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	27148328	159440891	Rat
631208	Bw1	Body weight QTL1	5.09		mesenteric fat pad mass (VT:0010427)	mesenteric fat pad weight to body weight ratio (CMO:0000654)	2	44904355	85286097	Rat
1331760	Bp206	Blood pressure QTL 206	3.62454		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	4265106	205135428	Rat
1358899	Kidm23	Kidney mass QTL 23	3.88		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	27148328	159440891	Rat
1358908	Bw49	Body weight QTL 49	3.36		body mass (VT:0001259)	body weight (CMO:0000012)	2	27148557	159440760	Rat
1300155	Bp174	Blood pressure QTL 174	4.09		arterial blood pressure trait (VT:2000000)	absolute change in mean arterial blood pressure (CMO:0000533)	2	44537979	112567334	Rat
2293835	Kiddil5	Kidney dilation QTL 5	3.8		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	2	44537979	159440891	Rat
1358910	Kidm27	Kidney mass QTL 27	5.77		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	27148328	159440891	Rat
61355	Bp36	Blood pressure QTL 36	2.9		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	2	7605533	104774005	Rat
1358911	Kidm28	Kidney mass QTL 28	5.42		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	27148328	159440891	Rat
1358904	Cm39	Cardiac mass QTL 39	2.26		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	27148328	159440891	Rat
1354617	Bp240	Blood pressure QTL 240	4		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	28652666	83465677	Rat
1578664	Bmd9	Bone mineral QTL density 9	5		femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	2	5736325	50736325	Rat
2293843	Kiddil6	Kidney dilation QTL 6	3.1		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	2	44537979	184731399	Rat
1358887	Bw50	Body weight QTL 50	2.39		body mass (VT:0001259)	body weight (CMO:0000012)	2	27148557	159440760	Rat
2306903	Bp336	Blood pressure QTL 336		0.01	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	38426449	111295694	Rat
1298085	Bp165	Blood pressure QTL 165		0.0006	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	44537979	205135428	Rat
2290453	Scl55	Serum cholesterol level QTL 55	2.83		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	2	28652666	139067443	Rat
152025206	Hrtrt23	Heart rate QTL 23	5.98		heart pumping trait (VT:2000009)		2	30219200	171802126	Rat
1358894	Kidm24	Kidney mass QTL 24	4.03		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	27148328	159440891	Rat
731184	Mamtr4	Mammary tumor resistance QTL 4		0.0003	mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	2	18227137	63227137	Rat
152025204	Hrtrt22	Heart rate QTL 22	5.6		heart pumping trait (VT:2000009)		2	30219200	171802126	Rat
61371	Edpm1	Estrogen-dependent pituitary mass QTL 1	4	0.05	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	2	36868643	81868643	Rat
1354601	Slep1	Serum leptin concentration QTL 1	5.39		blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	2	44904355	89904355	Rat
1582246	Cm60	Cardiac mass QTL 60	5.8		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	33269996	78269996	Rat
1354603	Bp243	Blood pressure QTL 243	3.9		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	28652666	73652666	Rat

Markers in Region

RH130385

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	45,231,878 - 45,232,081 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	45,454,336 - 45,454,538	NCBI	Rnor6.0
Rnor_5.0	2	64,486,409 - 64,486,611	UniSTS	Rnor5.0
RGSC_v3.4	2	45,013,937 - 45,014,139	UniSTS	RGSC3.4
Celera	2	41,000,265 - 41,000,467	UniSTS
RH 3.4 Map	2	282.0	UniSTS
Cytogenetic Map	2	q14	UniSTS

RH135330

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	45,238,595 - 45,238,790 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	45,461,053 - 45,461,247	NCBI	Rnor6.0
Rnor_5.0	2	64,493,126 - 64,493,320	UniSTS	Rnor5.0
RGSC_v3.4	2	45,020,654 - 45,020,848	UniSTS	RGSC3.4
Celera	2	41,006,982 - 41,007,176	UniSTS
RH 3.4 Map	2	282.8	UniSTS
Cytogenetic Map	2	q14	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001107652	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473955	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000066764 ⟹ ENSRNOP00000063122

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	46,965,498 - 46,991,516 (-)	Ensembl
mRatBN7.2 Ensembl	2	45,232,325 - 45,258,345 (-)	Ensembl
Rnor_6.0 Ensembl	2	45,454,782 - 45,480,798 (-)	Ensembl

RefSeq Acc Id:

NM_001107652 ⟹ NP_001101122

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	46,965,498 - 46,991,516 (-)	NCBI
mRatBN7.2	2	45,232,325 - 45,258,345 (-)	NCBI
Rnor_6.0	2	45,454,782 - 45,480,798 (-)	NCBI
Rnor_5.0	2	64,486,855 - 64,512,619 (-)	NCBI
RGSC_v3.4	2	45,014,383 - 45,040,586 (-)	RGD
Celera	2	41,000,711 - 41,026,746 (-)	RGD

Sequence:

show sequence

TGCAGTCGCTGCGGTGAGCAGAGCGGATCTGCACGGAGGCTACGAGCGGAACGGGGAGCAGACC
GTGCGTTGCCCTCAAGGCTCGCTCCCTTCGGCGCTCAGGGGCGCGGGTACTGACCGCGGGGCCC
TCGGACCGGCCCGGGCTCGGGGCGCCAGGCTCGAGACCATGGCGCTACGCGCCCGGGCGCTCTA
CGACTTTAGGTCCGAGAACCCCGGTGAGATCTCCCTGCGGGAGCACGAGGTGTTGAGCTTGTGC
AGCGAGCAGGACATCGAGGGCTGGCTTGAAGGGATCAACAGCCGCGGCGACCGCGGCCTCTTCC
CGGCTTCGTACGTGCAGGTTATCCGTGCGCCGGAGCCTGGCCCTCCGGCCGACGGCGGCCCAGG
AGCTCCGGCCCGCTACGCCAACGTGCCGCCCGGCGGCTTCGAGCCTCTGCCAGCCGCGCCGCCC
GCTGCCTTCCAGCCGCTGCTGCAGCCGCAGGCGTCGCCCGGTTCCTTCCAGTCGCCGGGCGCCG
GCTTTACCTACGGCGGGGGCGCCCCGCAGCCGTCGCCCCAGCAGCTCTACGGTGCTTACCAGGC
CAGCCTAGGCAGCGACGATGACTGGGACGACGAGTGGGACGACAGCTCCACAGTGGCAGACGAG
CCAGGCGCGTTGGGCAGCGGTGCGTACCCGGACCTCGACGGTTCGTCCTCAGCGGGCGGCGGCG
CGGCCGGCCGCTACCGCTTGTCCACACGCTCGGACCTGTCGCTGGGCTCCCGTGGCGTCTCAGC
GCCCCCGCCGCATCAAGCGTCTGGAGCCAAGAGCTCCGCCACGGTGAGCCGCAACCTCAATCGG
TTCTCCACCTTCGTCAAGTCGGGCGGGGAGGCGTTCGTGCTGGGAGAGGCGTCAGGCTTCGTGA
AGGATGGGGACAAGCTGTGCGTGGTGCTGGGTCCCTACGGCCCCGAGTGGCAGGAGAACCCCTA
CCCCTTCCAGTGCACCATCGACGATCCCACCAAGCAGACCAAGTTCAAGGGTATGAAGAGCTAC
ATCTCTTACAAGCTGGTGCCCACGCATACCCAGGTGCCCGTGCACAGGCGCTATAAGCACTTCG
ACTGGCTGTATGCGCGCCTGGCGGAGAAATTCCCGGTCATCTCGGTGCCCCATCTGCCCGAGAA
GCAGGCCACCGGGCGCTTCGAGGAGGACTTCATCTCCAAGCGCAGGAAGGGTCTGATCTGGTGG
ATGAACCACATGGCCAGTCACCCAGTGCTGGCCCAGTGCGACGTCTTCCAGCATTTCCTGACCT
GCCCCAGCAGCACTGATGAGAAGGCCTGGAAACAGGGTAAGCGGAAGGCTGAGAAGGATGAGAT
GGTGGGCGCCAACTTCTTCCTCACTCTGAGCACACCACCTGCGGCCGCCCTGGACCTGCAGGAG
GTGGAAAGCAAGATCGATGGCTTCAAATGCTTCACCAAGAAGATGGATGACAGCGCGTTGCAGC
TCAACCACACTGCCAACGAGTTTGCGCGCAAGCAGGTGACTGGCTTCAAGAAGGAGTATCAGAA
GGTGGGCCAGTCCTTTCGGGGCCTCAGCCAAGCCTTTGAGCTGGATCAGCAGGCCTTCTCCGTG
GGTCTGAATCAGGCCATTGCCTTCACCGGAGACGCCTATGATGCCATCGGTGAACTCTTCGCTG
AGCAGCCCAGGCAGGACCTGGACCCAGTCATGGACCTGTTAGCACTGTATCAGGGGCACCTGGC
CAACTTCCCAGACATCATCCATGTTCAGAAAGGAGCTCTTACCAAAGTAAAGGAGAGTAGACGA
CACGTGGAAGAAGGGAAGATGGAGGTCCAAAAGGCCGACGGCATTCAAGACCGCTGTAACACTA
TTTCCTTCGCCACGTTGGCCGAGATTCATCACTTCCATCAAATTAGAGTAAGAGACTTTAAATC
ACAGATGCAGCATTTTTTACAACAACAAATAATATTTTTCCAAAAAGTGACACAGAAGTTGGAA
GAAGCTCTTCATAAATATGACAGCGTCTGATGGCTGCACATGGGACGCACATCTGTTTTCAGTT
CAAGGATAATTTCTACAGCAGAGCAGAAACTGCTTTCTAAGAGCTATTGCCAACTATAGGCGGT
GGTACCAGGACGGTTTTGTGTTCAACTGAAACCCGGCTGGATATATAATTACGTAGGAGAGAAG
CAGTTAATATGGTTATGTAGCAGAAACAGTACCACACTTTGTAACTAAATTATACTATGTATGC
CCACACTACTATTGTAACTTTTGATAATGATTATACTATTTGCCTTATTGCTTTTGAAGTATGG
GTATATTAGTGTGTACTTTGTAGACCTCAAAGCCCATGAAGAGTCTCAAAGAAGCTGGCTGGAT
GAAGCCTGCTGAGGATGCCTTTTTAGTCTCATAGATCGAGATGACCTAAACTCAACCTACTCTG
TTTACAAACTCCAACTAGAGCAGCTCTGCGACTTTGTGCCTTCAGACCGGTTGTTTTCCTTTCT
GTCCCACCTGTGTTTGAGCCCCAACTTCTGATGGAAGGAGCGAAAGGCGAGCACTGGTGACAGC
CGATGAAAACCTCCCATTTCTGGGTCAGTGGTAGAACCAGTGGCCATCACTTTGCACAGGAAGC
ATCGCCTGGTAAGATGCTGGCAGTGACAGAGGCATGAGACGCTCGCTCTGCTGTCTCTGGATGT
GAAGTCTCGTAGGGGAAAAGGCTGTGCACCGTATTCCCTTACAGCTGTTTGTAGCACACGGCCT
CGACTCCAGGGTCACACAGACTGGGCCTGGGGATTTCAGCAATGCCCTTAGCACGTGGGGAAGA
ATCCAATCGGGGATAAAGTGTAGAAGCAGTGGGTGAAAATGCACTCCGTCTTAGTTTGGGGAAG
TGTCTCCTGTCTTTTTTCTTTTTTTCTTTCTTTCTCTCTTTTTTAGCTTGAAATTTCCTTTTAA
TGTTCAGCTTTCTGTTTTGATTTCAAATGGATCTACACTGTTAACTGAATGATGAGACTCCACT
GTGATTCACTCGTTTACTTAATCAAAAAATTTCAGGGATGTCTGTAAATTTCAGTGTTGTGCAC
AACAAGAAGTGCTGTTGGTTGATTTAAGGAGGGACCAGAAATAATTTCTACTATTCCAGTAATG
AAGGAAAAAAAATACTGATTTATACTGTTTTTAAAAACTAAATATTAATAAAGCCCCCTGTCAG
AAATTTAACCTTAAAAATTATTTTAAATATCATCCTATATTATTAGAAGGGAACTACAAGTGAC
TGATAAATACCAAAAAGATTCACAAGCAGCTTCATTTAAAAAGCACAAAGAGGTTCTGGTGTGA
AATGCCCAAATCTCAAATGTTTTCTGTAGTTCTGAGTTTACAGATGTAAAAGCTGTCCCTGAAG
GCTGCAGTACCTGTATCTGCTGTCCCTGTGAACTACACTCGCACCACCCCAGAAACCCTGGTAC
TGATAGGGTAGCGTGGGGGTACAGTCTCAGAGGGGGTGAGCCACAGTCACCCAACGGGGTCAGC
TTGCAGAAAGACCAAAACAGGAAAGGCGAGTGGGATAATTACTTAACAGCACATTCACTCTCTA
CGAAGTAATCACATATGGGTTGAAATTTGAAGAGCAGATTGTGATCATTTTGACCTCTGGTCAA
ATCCTTGTACTTGAGAACTTTGAGGCGGACGTGGCATCACGTGGCGTTGCCTTTACTACAGGCC
CGTGGGACTGTTGCCAAAAGTCGTGTTCTCTGAAAAAAGCAGTCCCTCTCGTTGACTGCAAAGT
ACAGTTAGGTAAAGAAAACCCATATATATTTAAAAACTAATTTTATTCCAGAATTTTGGACGTT
ATAAGTTTGAATTGTCACTGAAGAAGCAAGCTCTTCCTCGTTTCAAATGATTTGGTCACATTTA
TTTGCCTCTTCGTTTTGATGGTGGTTTGATTCTTTTTTCTCCTAATGAAGTTAGTAAACTTGTG
CAGTAGTAACAAGGACATTACCTGAGGTGTCTTGTATGATTGTGGTTTAGCCAGGGTGGACACA
GCTTAAATCACAAACTAAAGATCAAAGTACAAAGACGTGTGCAGTCTACGCTGCCTCCTCCCGA
GATAACTTTCCTCCCTCCTAACCTCGTAGCATAATGCCACCAATTCATGGGGCTGTAAATGAAT
TCTGTGGGTTAATGCACCAGACTTACCAGTGTCCATTTTCATCCAAGATTCTTACTCTCTAACG
TTCTTGGTCCTATTGAAACATTTCAGTATCTAAACATACTGCAATGTTAATACCCAAGAGAAAA
GCCATTACGTGTATGCTGGTCACATGATCAGTGTGGTACAGTTTTGTTACTGTTGTTGTTTTGT
TTCGTCGTTTCTGTTTTTTAAATAAACTATCATGCCCTTCAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001101122	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM10374	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000063122
	ENSRNOP00000063122.1

RefSeq Acc Id:

NP_001101122 ⟸ NM_001107652

- UniProtKB:

D3ZZ38 (UniProtKB/TrEMBL), A6I5R6 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MALRARALYDFRSENPGEISLREHEVLSLCSEQDIEGWLEGINSRGDRGLFPASYVQVIRAPEP
GPPADGGPGAPARYANVPPGGFEPLPAAPPAAFQPLLQPQASPGSFQSPGAGFTYGGGAPQPSP
QQLYGAYQASLGSDDDWDDEWDDSSTVADEPGALGSGAYPDLDGSSSAGGGAAGRYRLSTRSDL
SLGSRGVSAPPPHQASGAKSSATVSRNLNRFSTFVKSGGEAFVLGEASGFVKDGDKLCVVLGPY
GPEWQENPYPFQCTIDDPTKQTKFKGMKSYISYKLVPTHTQVPVHRRYKHFDWLYARLAEKFPV
ISVPHLPEKQATGRFEEDFISKRRKGLIWWMNHMASHPVLAQCDVFQHFLTCPSSTDEKAWKQG
KRKAEKDEMVGANFFLTLSTPPAAALDLQEVESKIDGFKCFTKKMDDSALQLNHTANEFARKQV
TGFKKEYQKVGQSFRGLSQAFELDQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDPVMDL
LALYQGHLANFPDIIHVQKGALTKVKESRRHVEEGKMEVQKADGIQDRCNTISFATLAEIHHFH
QIRVRDFKSQMQHFLQQQIIFFQKVTQKLEEALHKYDSV

hide sequence

Ensembl Acc Id:

ENSRNOP00000063122 ⟸ ENSRNOT00000066764

Protein Domains

PX SH3

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZZ38-F1-model_v2	AlphaFold	D3ZZ38	1-615	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13691144

Promoter ID:

EPDNEW_R1669

Type:

multiple initiation site

Name:

Snx18_1

Description:

sorting nexin 18

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	2	45,480,795 - 45,480,855	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1310367	AgrOrtholog
BioCyc Gene	G2FUF-54355	BioCyc
Ensembl Genes	ENSRNOG00000010971	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000066764	ENTREZGENE
	ENSRNOT00000066764.3	UniProtKB/TrEMBL
Gene3D-CATH	1.20.1270.60	UniProtKB/TrEMBL
	3.30.1520.10	UniProtKB/TrEMBL
	SH3 Domains	UniProtKB/TrEMBL
InterPro	AH/BAR-dom	UniProtKB/TrEMBL
	IPR001683	UniProtKB/TrEMBL
	PX_dom_sf	UniProtKB/TrEMBL
	SH3-like_dom	UniProtKB/TrEMBL
	SH3_domain	UniProtKB/TrEMBL
	SNX18_PX	UniProtKB/TrEMBL
	SNX18_SH3	UniProtKB/TrEMBL
	Snx9	UniProtKB/TrEMBL
	Sorting_nexin_WASP-bd-dom	UniProtKB/TrEMBL
KEGG Report	rno:310097	UniProtKB/TrEMBL
NCBI Gene	310097	ENTREZGENE
PANTHER	PTHR45827:SF4	UniProtKB/TrEMBL
	SORTING NEXIN	UniProtKB/TrEMBL
Pfam	BAR_3_WASP_bdg	UniProtKB/TrEMBL
	PF00787	UniProtKB/TrEMBL
	SH3_9	UniProtKB/TrEMBL
PhenoGen	Snx18	PhenoGen
PIRSF	Snx9	UniProtKB/TrEMBL
PROSITE	PS50195	UniProtKB/TrEMBL
	SH3	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000010971	RatGTEx
SMART	SH3	UniProtKB/TrEMBL
	SM00312	UniProtKB/TrEMBL
Superfamily-SCOP	64268	UniProtKB/TrEMBL
	SH3	UniProtKB/TrEMBL
UniProt	A6I5R6	ENTREZGENE, UniProtKB/TrEMBL
	D3ZZ38	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-03-19	Snx18	sorting nexin 18	Snag1_predicted	sorting nexin associated golgi protein 1 (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-12	Snag1_predicted	sorting nexin associated golgi protein 1 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD