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Gene: Mettl25 (methyltransferase like 25) Rattus norvegicus

Analyze

Symbol:

Mettl25

Name:

methyltransferase like 25

RGD ID:

1310270

Description:

Orthologous to human METTL25 (methyltransferase like 25); INTERACTS WITH 6-propyl-2-thiouracil; acrylamide; amitrole.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

hypothetical protein LOC314798; LOC314798; methyltransferase-like protein 25; probable methyltransferase-like protein 25; RGD1310270; similar to CG33154-PB; uncharacterized protein LOC314798

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	METTL25 (methyltransferase like 25)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Mettl25 (methyltransferase like 25)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Mettl25 (methyltransferase like 25)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	METTL25 (methyltransferase like 25)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	METTL25 (methyltransferase like 25)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Mettl25 (methyltransferase like 25)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	METTL25 (methyltransferase like 25)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	METTL25 (methyltransferase like 25)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Mettl25 (methyltransferase like 25)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Mettl25 (methyltransferase like 25)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Mettl25 (methyltransferase like 25)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	METTL25 (methyltransferase like 25)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	METTL25 (methyltransferase like 25)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	mettl25 (methyltransferase like 25)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG33964	Alliance	DIOPT (Hieranoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG33964	Alliance	DIOPT (InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	mettl25	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	mettl25	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	42,948,934 - 43,029,610 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	7	42,948,934 - 43,029,809 (-)	Ensembl				GRCr8
mRatBN7.2	7	41,062,276 - 41,143,056 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	41,062,276 - 41,143,423 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	7	42,961,799 - 43,042,744 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	45,164,858 - 45,245,808 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	44,920,977 - 45,000,197 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	47,847,812 - 47,928,495 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	47,847,822 - 47,928,674 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	7	47,862,494 - 47,942,777 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	7	44,415,537 - 44,496,537 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	7	37,938,606 - 38,019,225 (-)	NCBI		Celera
RGSC_v3.1	7	44,435,864 - 44,516,850 (-)	NCBI
Cytogenetic Map	7	q21	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17beta-estradiol (ISO)

5-aza-2'-deoxycytidine (ISO)

6-propyl-2-thiouracil (EXP)

acrylamide (EXP)

aflatoxin B1 (ISO)

aflatoxin M1 (ISO)

amitrole (EXP)

aristolochic acid A (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

Butylbenzyl phthalate (ISO)

cadmium dichloride (ISO)

caffeine (ISO)

cisplatin (ISO)

cyclosporin A (ISO)

methylmercury chloride (ISO)

paracetamol (EXP)

sodium fluoride (ISO)

sulfadimethoxine (EXP)

temozolomide (ISO)

triphenyl phosphate (ISO)

valproic acid (ISO)

vinclozolin (EXP)

References

References - curated

#	Reference Title	Reference Citation
1.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932

Genomics

Comparative Map Data

Mettl25
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	42,948,934 - 43,029,610 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	7	42,948,934 - 43,029,809 (-)	Ensembl				GRCr8
mRatBN7.2	7	41,062,276 - 41,143,056 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	41,062,276 - 41,143,423 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	7	42,961,799 - 43,042,744 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	45,164,858 - 45,245,808 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	44,920,977 - 45,000,197 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	47,847,812 - 47,928,495 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	47,847,822 - 47,928,674 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	7	47,862,494 - 47,942,777 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	7	44,415,537 - 44,496,537 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	7	37,938,606 - 38,019,225 (-)	NCBI		Celera
RGSC_v3.1	7	44,435,864 - 44,516,850 (-)	NCBI
Cytogenetic Map	7	q21	NCBI

METTL25
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	82,358,529 - 82,479,239 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	82,358,500 - 82,479,239 (+)	Ensembl			hg38	GRCh38
GRCh37	12	82,752,308 - 82,873,018 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	81,276,455 - 81,397,076 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	12	82,419,836 - 82,540,592 (+)	NCBI		Celera
Cytogenetic Map	12	q21.31	NCBI
HuRef	12	79,809,513 - 79,930,276 (+)	NCBI		HuRef
CHM1_1	12	82,718,129 - 82,838,893 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	12	82,337,989 - 82,458,720 (+)	NCBI		T2T-CHM13v2.0

Mettl25
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	105,599,052 - 105,677,246 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	105,599,050 - 105,677,241 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	10	105,763,185 - 105,841,380 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	105,763,189 - 105,841,380 (-)	Ensembl			mm10	GRCm38
MGSCv37	10	105,200,241 - 105,278,436 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	10	105,167,357 - 105,245,464 (-)	NCBI		MGSCv36	mm8
Celera	10	107,712,287 - 107,790,727 (-)	NCBI		Celera
Cytogenetic Map	10	D1	NCBI
cM Map	10	55.12	NCBI

Mettl25
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955405	20,738,842 - 20,822,262 (+)	Ensembl
ChiLan1.0	NW_004955405	20,738,822 - 20,821,256 (+)	NCBI	ChiLan1.0	ChiLan1.0

METTL25
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	90,402,756 - 90,523,334 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	90,399,087 - 90,519,783 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	79,873,181 - 79,993,799 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	82,981,718 - 83,102,110 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	82,981,718 - 83,102,115 (+)	Ensembl			panPan2	panpan1.1

METTL25
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	15	24,373,574 - 24,501,226 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	15	24,373,603 - 24,481,583 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	15	24,804,479 - 24,932,177 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	15	24,752,404 - 24,880,103 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	15	24,752,453 - 24,869,047 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	15	24,329,749 - 24,457,556 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	15	24,378,610 - 24,506,344 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	15	24,619,632 - 24,727,755 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Mettl25
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	35,633,834 - 35,897,488 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936507	337,332 - 448,009 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936507	337,943 - 448,148 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

METTL25
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	99,227,750 - 99,358,587 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	5	99,216,635 - 99,358,585 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	104,179,077 - 104,213,187 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

METTL25
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	77,798,362 - 77,934,452 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	77,798,393 - 77,868,464 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666037	167,467,480 - 167,593,494 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Mettl25
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624837	1,693,608 - 1,811,941 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624837	1,693,562 - 1,811,110 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Mettl25
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	1	184,095,118 - 184,176,528 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Mettl25
605 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	178
Count of miRNA genes:	129
Interacting mature miRNAs:	138
Transcripts:	ENSRNOT00000038144
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1354644	Spl4	Serum phospholipid level QTL 4	4.9		blood phospholipid amount (VT:0006084)	blood phospholipid level (CMO:0001169)	7	21541977	51639954	Rat
7411569	Bw137	Body weight QTL 137		0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	7	23807606	68807606	Rat
9590102	Sffal5	Serum free fatty acids level QTL 5	8.62	0.001	blood free fatty acid amount (VT:0001553)	plasma free fatty acids level (CMO:0000546)	7	7216097	52216097	Rat
1578652	Bmd15	Bone mineral density QTL 15	5.2		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	7	10517086	62346019	Rat
631503	Bp102	Blood pressure QTL 102	1.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	1709527	46709527	Rat
1549840	Bss5	Bone structure and strength QTL 5	9.8		femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	7	26638057	71638057	Rat
1300127	Srn1	Serum renin concentration QTL 1	3.87		blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	7	24179478	86817926	Rat
1358361	Sradr5	Stress Responsive Adrenal Weight QTL 5	5.55		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	7	31770293	110435881	Rat
2298547	Neuinf5	Neuroinflammation QTL 5	3.7		nervous system integrity trait (VT:0010566)	spinal cord Cd74 protein level (CMO:0002131)	7	10112916	60150541	Rat
631513	Scl7	Serum cholesterol level QTL 7	4.1		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	7	39845902	84845902	Rat
10059592	Kidm45	Kidney mass QTL 45	3.95	0.025	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	7	9460877	54460877	Rat
1354637	Scl30	Serum cholesterol level QTL 30	3.7		blood cholesterol amount (VT:0000180)	blood total cholesterol level (CMO:0000051)	7	21541977	51639954	Rat
10755453	Coatc12	Coat color QTL 12		0	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	7	32998702	77998702	Rat
61410	Bw19	Body weight QTL 19	6.2	0.001	body mass (VT:0001259)	body weight (CMO:0000012)	7	1669658	46669658	Rat
7411605	Foco14	Food consumption QTL 14	24.1	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	7	36178764	81178764	Rat
1643004	Pain2	Pain QTL 2	1		mechanical nociception trait (VT:0002734)	self mutilation severity score (CMO:0002145)	7	10112916	99900612	Rat
1300149	Cm6	Cardiac mass QTL 6	4.09		heart mass (VT:0007028)	heart left ventricle weight to body weight ratio (CMO:0000530)	7	1	104117804	Rat
631534	Lnnr1	Liver neoplastic nodule remodeling QTL 1	3.85	0.001	liver integrity trait (VT:0010547)	liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)	7	36178764	81178764	Rat
634336	Anxrr17	Anxiety related response QTL 17	3.66		locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	7	1509236	116977875	Rat
61357	Bp38	Blood pressure QTL 38	1.6	0.052	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	40540077	123682549	Rat
2303629	Vencon3	Ventilatory control QTL 3	7.25		respiration trait (VT:0001943)	respiration rate (CMO:0000289)	7	42996226	58678836	Rat
70190	Mcs6	Mammary carcinoma susceptibility QTL 6	2.29		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	7	28624575	65788017	Rat
1300132	Bp182	Blood pressure QTL 182	3.49		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	7	21541977	86817926	Rat
1300138	Hrtrt9	Heart rate QTL 9	4.72		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	7	10498820	55498820	Rat
738033	Anxrr6	Anxiety related response QTL 6	4.1		exploratory behavior trait (VT:0010471)	percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)	7	17460447	62460447	Rat
70207	Niddm31	Non-insulin dependent diabetes mellitus QTL 31	3.9		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	7	20057232	65057232	Rat
61439	Cia8	Collagen induced arthritis QTL 8	5.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	7	27182914	72182914	Rat

Markers in Region

D7Rat103

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	7	42,996,226 - 42,996,457 (+)	Marker Load Pipeline
mRatBN7.2	7	41,109,692 - 41,109,925 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	47,895,099 - 47,895,329	NCBI	Rnor6.0
Rnor_5.0	7	47,909,781 - 47,910,011	UniSTS	Rnor5.0
RGSC_v3.4	7	44,462,790 - 44,463,229	RGD	RGSC3.4
RGSC_v3.4	7	44,462,830 - 44,463,060	UniSTS	RGSC3.4
Celera	7	37,985,977 - 37,986,207	UniSTS
RGSC_v3.1	7	44,483,101 - 44,483,331	RGD
RH 3.4 Map	7	361.0	RGD
RH 3.4 Map	7	361.0	UniSTS
RH 2.0 Map	7	310.9	RGD
SHRSP x BN Map	7	25.4	RGD
FHH x ACI Map	7	24.58	RGD
Cytogenetic Map	7	q21	UniSTS

RH139869

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	41,136,148 - 41,136,367 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	47,921,527 - 47,921,745	NCBI	Rnor6.0
Rnor_5.0	7	47,935,812 - 47,936,030	UniSTS	Rnor5.0
RGSC_v3.4	7	44,489,630 - 44,489,848	UniSTS	RGSC3.4
Celera	7	38,012,318 - 38,012,536	UniSTS
Cytogenetic Map	7	q21	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	164	91	90	59	91	59	6	355	191	11	143	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001108089	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017594845	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039079101	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039079105	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063263470	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063263472	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063263473	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010052971	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC127512	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC161980	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473960	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000038144 ⟹ ENSRNOP00000029686

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	42,948,934 - 43,029,809 (-)	Ensembl
mRatBN7.2 Ensembl	7	41,062,276 - 41,143,423 (-)	Ensembl
Rnor_6.0 Ensembl	7	47,847,822 - 47,928,674 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000094274 ⟹ ENSRNOP00000084690

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	42,948,934 - 43,029,809 (-)	Ensembl
mRatBN7.2 Ensembl	7	41,062,276 - 41,143,423 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000111870 ⟹ ENSRNOP00000079516

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	7	41,062,276 - 41,136,117 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000116499 ⟹ ENSRNOP00000077606

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	42,951,649 - 43,029,809 (-)	Ensembl
mRatBN7.2 Ensembl	7	41,062,341 - 41,143,015 (-)	Ensembl

RefSeq Acc Id:

NM_001108089 ⟹ NP_001101559

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	42,948,934 - 43,029,568 (-)	NCBI
mRatBN7.2	7	41,062,276 - 41,143,056 (-)	NCBI
Rnor_6.0	7	47,847,812 - 47,928,434 (-)	NCBI
Rnor_5.0	7	47,862,494 - 47,942,777 (-)	NCBI
RGSC_v3.4	7	44,415,537 - 44,496,537 (-)	RGD
Celera	7	37,938,606 - 38,019,225 (-)	RGD

Sequence:

show sequence

AGAGAGGGGGTCGCGCGGCCATGTTGGCGCCACCTGCAGCCCTGGAGGGCGAGCGTCATGGCGG
CGGCCAGCCCTCTCCCCAGGGCCCCGGACCTGCCCACGCTGCACGCCACGTTACAGGACTTGCT
GAGCTTCCTAAGGGGCGCCCTGGCCATTTCCAGTGCGCATACAGTGGACTTCTACACCAAGTCG
ATCTGGCAAGAGCTGGTCGACTTGCCCCCTGAGAGCGTGCTGGCAACGCTGAGGAAGTCGGCGG
CGGAGGCCGAGCTGCACGAGACGCTTCCCCTGGGGGAGGCAGAGGCGGGATCAGGTTTCATCGA
TCTCCCCAAAATATTTTGTGAAACCTCTCAGAAGCTGTTGAGTGTGGAAGCCTTTGTGCTCACT
GCGAAACACTACTCTGTGCAGAACTTGGGACTGTGCACTCCTTCTGAGCAGCTGCTTACAGCCC
TCCGAGTAAATACAGAACAGAGAACTGATGAAAATGTGAAGGCAATTGAGTTTATGAATACAAA
AAAATCTCATGAGGTCCAGGCAATGTCAGAGCTAATCTGCAGTATTGCTGATTACTGTGGCTTA
AAGCAGATAATTGATGTGGGTTCTGGTAAAGGCTATCTAAGCTCCTTTTTGTCCTTAAAATACG
GTCTGAATGTTTATGGCATCGACTCCTCAAGCACTAACACTCATGGGGCTAAGGAGAGAAACAG
GAAGTTGAAGAAACATTGGAACCTCTGTCATTCTCAGTCAAGAGCAGACAGTAACGGATTGGTA
TTAAAAATGCCAAAAGAGTCGAAAGTGCAAAGCAGAAGCAAGTGCGAGGGGGAGTCCGAGCGTG
TGCAGAAGAGCAGGCGTGGGGATGAAGACGCGTCTGCCGGTGTTCTGGCAGACTTCTCAGGGTC
TCCAGTTTCAGTCATCAGAAAACAGCAAAGAAATCTACATGCTCACCCAGTTGAAGAGGAAAAG
TTGTGTTGTGAAGATGCCTTTTCTCTCGTAGACTTTTTGCCTGTCGATGCCATCGAACCTACCT
CACAGGTGTGCCACACAGAAGCACCTGGACTCCGTAAAGAGAGAGGAAATGCAACCTCCAAAAC
AAGGGGCTCCAGCATATATTCACCGCTCACCTCGTTCATCACGGCGGACACACAACTGCACGAC
ATTATCGAAGATCTGGAGGACTGTTTGATGGTGGGGTTGCATACTTGTGGTGACCTTGCACCCA
ATACTCTGCGGATTTTTGCATCCAAGGCTGAAGTCAAGGGAGTTTGCAGTGTGGGTTGTTGCTA
CCATCTCTTATCTGAGGAATTTGAAAACCAGCATAAAGGATATGCTAAAGAAAACTGGGGATTT
CCAATGTGCCACTATCTGAAAGAGGAGAGATGGTGCTGTGGCCGTAATGCGAGAATGTCAGCAT
GTTTGGCATTGGAACGGGTTGTAGTTGGCCAAGGGCTACCTACTGAATCACTCTTCTATCGTGC
TGTTCTTCAGAATATTATTAAGGATTGTTATGGCATCAGCAAATGTGAGCAGTACGTTGGTAAA
ATTTACTCCAAATGTTCCTCTTTTCTGGAGTATGTCAGAGTGTCTCTAAAGAAGCTGGGATTAG
ATGAGTCCAAGATCTCTGCAGAAATTATAATGGACTACTATGAGAAATATAAGCCTAGAATGAA
TGAGCTAGAGGCATTTAATATGTTGAAAGTTGTCCTGGCTCCTTGCATAGAAACACTGATTCTT
CTTGATCGACTTTGTTACCTGAAGGAACAGGAAGACATAGCATGGTCTGCCCTCGTGAAGCTGT
TTGACCCTGTGCAGTCCCCCAGATGCTACGCTGTCATTGCTCTGAAGAAGCAGTGTGATCGCAG
CTGAAGCAGCTTGTTAGATAGCCTGGCTGGGGACCTACTCAAAGATCACTTTTCTAAACATTTA
TATCCTGTTATGTAAGCATTTTAAATCTATATTTTATATAATAAAATAATGACTAACAACATAA
AATCATAGTCAGTTTTTTCATTCTCAAAGCGTACGTTCATAAGAATTTATGTAAATATT

hide sequence

RefSeq Acc Id:

XM_039079101 ⟹ XP_038935029

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	42,948,991 - 43,029,610 (-)	NCBI
mRatBN7.2	7	41,062,333 - 41,143,036 (-)	NCBI

RefSeq Acc Id:

XM_039079105 ⟹ XP_038935033

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	42,948,991 - 43,029,314 (-)	NCBI
mRatBN7.2	7	41,062,333 - 41,142,880 (-)	NCBI

RefSeq Acc Id:

XM_063263470 ⟹ XP_063119540

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	42,996,297 - 43,029,610 (-)	NCBI

RefSeq Acc Id:

XM_063263472 ⟹ XP_063119542

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	42,948,991 - 43,019,440 (-)	NCBI

RefSeq Acc Id:

XM_063263473 ⟹ XP_063119543

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	42,948,991 - 43,019,440 (-)	NCBI

RefSeq Acc Id:

XR_010052971

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	42,990,087 - 43,029,610 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001101559	(Get FASTA)	NCBI Sequence Viewer
	XP_038935029	(Get FASTA)	NCBI Sequence Viewer
	XP_038935033	(Get FASTA)	NCBI Sequence Viewer
	XP_063119540	(Get FASTA)	NCBI Sequence Viewer
	XP_063119542	(Get FASTA)	NCBI Sequence Viewer
	XP_063119543	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI61980	(Get FASTA)	NCBI Sequence Viewer
	EDM16782	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000029686
	ENSRNOP00000029686.6
	ENSRNOP00000077606.2
	ENSRNOP00000084690
	ENSRNOP00000084690.1

RefSeq Acc Id:

NP_001101559 ⟸ NM_001108089

- UniProtKB:

B1WC27 (UniProtKB/TrEMBL), A0A8I5Y618 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAAASPLPRAPDLPTLHATLQDLLSFLRGALAISSAHTVDFYTKSIWQELVDLPPESVLATLRK
SAAEAELHETLPLGEAEAGSGFIDLPKIFCETSQKLLSVEAFVLTAKHYSVQNLGLCTPSEQLL
TALRVNTEQRTDENVKAIEFMNTKKSHEVQAMSELICSIADYCGLKQIIDVGSGKGYLSSFLSL
KYGLNVYGIDSSSTNTHGAKERNRKLKKHWNLCHSQSRADSNGLVLKMPKESKVQSRSKCEGES
ERVQKSRRGDEDASAGVLADFSGSPVSVIRKQQRNLHAHPVEEEKLCCEDAFSLVDFLPVDAIE
PTSQVCHTEAPGLRKERGNATSKTRGSSIYSPLTSFITADTQLHDIIEDLEDCLMVGLHTCGDL
APNTLRIFASKAEVKGVCSVGCCYHLLSEEFENQHKGYAKENWGFPMCHYLKEERWCCGRNARM
SACLALERVVVGQGLPTESLFYRAVLQNIIKDCYGISKCEQYVGKIYSKCSSFLEYVRVSLKKL
GLDESKISAEIIMDYYEKYKPRMNELEAFNMLKVVLAPCIETLILLDRLCYLKEQEDIAWSALV
KLFDPVQSPRCYAVIALKKQCDRS

hide sequence

Ensembl Acc Id:

ENSRNOP00000029686 ⟸ ENSRNOT00000038144

RefSeq Acc Id:	XP_038935029 ⟸ XM_039079101
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6GC39 (UniProtKB/TrEMBL), F6QFT3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038935033 ⟸ XM_039079105
- Peptide Label:	isoform X4
- UniProtKB:	A0A8I5ZNA4 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000077606 ⟸ ENSRNOT00000116499

Ensembl Acc Id:

ENSRNOP00000079516 ⟸ ENSRNOT00000111870

Ensembl Acc Id:

ENSRNOP00000084690 ⟸ ENSRNOT00000094274

RefSeq Acc Id:	XP_063119543 ⟸ XM_063263473
- Peptide Label:	isoform X5

RefSeq Acc Id:	XP_063119542 ⟸ XM_063263472
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_063119540 ⟸ XM_063263470
- Peptide Label:	isoform X2

Protein Domains

Methyltransferase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-F6QFT3-F1-model_v2	AlphaFold	F6QFT3	1-633	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1310270	AgrOrtholog
BioCyc Gene	G2FUF-34187	BioCyc
Ensembl Genes	ENSRNOG00000027451	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000038144	ENTREZGENE
	ENSRNOT00000038144.7	UniProtKB/TrEMBL
	ENSRNOT00000094274	ENTREZGENE
	ENSRNOT00000094274.2	UniProtKB/TrEMBL
	ENSRNOT00000116499.2	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.150	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:9029986	IMAGE-MGC_LOAD
InterPro	Methyltranfer_dom	UniProtKB/TrEMBL
	METTL25	UniProtKB/TrEMBL
	SAM-dependent_MTases-like	UniProtKB/TrEMBL
KEGG Report	rno:314798	UniProtKB/TrEMBL
MGC_CLONE	MGC:187792	IMAGE-MGC_LOAD
NCBI Gene	314798	ENTREZGENE
PANTHER	CGI-41 METHYLTRANSFERASE	UniProtKB/TrEMBL
	METHYLTRANSFERASE-LIKE PROTEIN 25-RELATED	UniProtKB/TrEMBL
Pfam	Methyltransf_32	UniProtKB/TrEMBL
PhenoGen	Mettl25	PhenoGen
RatGTEx	ENSRNOG00000027451	RatGTEx
Superfamily-SCOP	SSF53335	UniProtKB/TrEMBL
UniProt	A0A8I5Y618	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I5ZNA4	ENTREZGENE
	A0A8I6GC39	ENTREZGENE, UniProtKB/TrEMBL
	B1WC27	ENTREZGENE, UniProtKB/TrEMBL
	F6QFT3	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2012-10-10	Mettl25	methyltransferase like 25	RGD1310270	similar to CG33154-PB	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	RGD1310270	similar to CG33154-PB	RGD1310270_predicted	similar to CG33154-PB (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-20	RGD1310270_predicted	similar to CG33154-PB (predicted)	LOC314798_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC314798_predicted	similar to CG33154-PB (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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