Smtn (smoothelin) - Rat Genome Database

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Gene: Smtn (smoothelin) Rattus norvegicus
Analyze
Symbol: Smtn
Name: smoothelin
RGD ID: 1310216
Description: Predicted to act upstream of or within negative regulation of systemic arterial blood pressure and positive regulation of cardiac muscle contraction. Orthologous to human SMTN (smoothelin); INTERACTS WITH 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC103690128; LOC289734; smoothelin-like
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81482,622,223 - 82,644,525 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1482,621,375 - 82,644,514 (-)EnsemblGRCr8
mRatBN7.21478,398,595 - 78,420,908 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1478,397,778 - 78,420,886 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1482,839,785 - 82,862,070 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01484,079,891 - 84,102,176 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01480,525,655 - 80,547,941 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01483,755,141 - 83,776,871 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1483,755,142 - 83,776,863 (-)Ensemblrn6Rnor6.0
Rnor_5.01480,301,566 - 80,303,230 (-)NCBIRnor_5.0Rnor_5.0rn5
Rnor_5.01484,443,088 - 84,464,813 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41484,160,580 - 84,182,869 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1477,311,041 - 77,333,331 (-)NCBICelera
RGSC_v3.11484,179,725 - 84,202,043 (-)NCBI
Cytogenetic Map14q21NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View
COVID-19  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-butoxyethanol  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
acetamide  (EXP)
acrolein  (ISO)
acrylamide  (EXP)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
alpha-pinene  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
avobenzone  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bleomycin A2  (ISO)
Bufotalin  (ISO)
Butylbenzyl phthalate  (ISO)
C60 fullerene  (EXP)
cadmium dichloride  (ISO)
caffeine  (ISO)
cannabidiol  (ISO)
chlordecone  (ISO)
chlorpyrifos  (ISO)
cisplatin  (EXP,ISO)
clofibrate  (ISO)
cocaine  (EXP)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
dibutyl phthalate  (EXP,ISO)
dicrotophos  (ISO)
diethyl maleate  (EXP)
diuron  (EXP)
doxorubicin  (ISO)
elemental selenium  (ISO)
endosulfan  (EXP)
ethyl methanesulfonate  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
glycidol  (EXP)
inulin  (ISO)
isoprenaline  (ISO)
lead diacetate  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methotrexate  (ISO)
methoxychlor  (EXP)
methyl methanesulfonate  (ISO)
methylparaben  (ISO)
nitrates  (ISO)
nitrofen  (EXP)
okadaic acid  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
pirinixic acid  (ISO)
progesterone  (ISO)
quercetin  (ISO)
resveratrol  (EXP,ISO)
selenium atom  (ISO)
silicon dioxide  (EXP,ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (ISO)
thiram  (ISO)
titanium dioxide  (ISO)
triptonide  (ISO)
trovafloxacin  (ISO)
urethane  (ISO)
vitamin E  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
actin cytoskeleton  (IEA,ISO)
nucleoplasm  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11998981   PMID:12477932   PMID:18678771   PMID:31505169  


Genomics

Comparative Map Data
Smtn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81482,622,223 - 82,644,525 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1482,621,375 - 82,644,514 (-)EnsemblGRCr8
mRatBN7.21478,398,595 - 78,420,908 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1478,397,778 - 78,420,886 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1482,839,785 - 82,862,070 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01484,079,891 - 84,102,176 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01480,525,655 - 80,547,941 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01483,755,141 - 83,776,871 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1483,755,142 - 83,776,863 (-)Ensemblrn6Rnor6.0
Rnor_5.01480,301,566 - 80,303,230 (-)NCBIRnor_5.0Rnor_5.0rn5
Rnor_5.01484,443,088 - 84,464,813 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41484,160,580 - 84,182,869 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1477,311,041 - 77,333,331 (-)NCBICelera
RGSC_v3.11484,179,725 - 84,202,043 (-)NCBI
Cytogenetic Map14q21NCBI
SMTN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382231,064,118 - 31,104,624 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2231,064,105 - 31,104,757 (+)Ensemblhg38GRCh38
GRCh372231,460,104 - 31,500,610 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362229,807,305 - 29,830,609 (+)NCBIBuild 36Build 36hg18NCBI36
Build 342229,801,858 - 29,825,163NCBI
Celera2215,277,437 - 15,300,741 (+)NCBICelera
Cytogenetic Map22q12.2NCBI
HuRef2214,439,094 - 14,462,417 (+)NCBIHuRef
CHM1_12231,437,118 - 31,460,447 (+)NCBICHM1_1
T2T-CHM13v2.02231,527,653 - 31,568,123 (+)NCBIT2T-CHM13v2.0
Smtn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39113,467,522 - 3,489,337 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl113,467,521 - 3,490,612 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38113,517,522 - 3,539,292 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl113,517,523 - 3,540,612 (-)Ensemblmm10GRCm38
MGSCv37113,417,525 - 3,439,295 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36113,417,526 - 3,439,242 (-)NCBIMGSCv36mm8
Celera114,008,414 - 4,030,184 (-)NCBICelera
Cytogenetic Map11A1NCBI
cM Map112.47NCBI
Smtn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554555,273,602 - 5,297,604 (+)Ensembl
ChiLan1.0NW_0049554555,271,615 - 5,294,151 (+)NCBIChiLan1.0ChiLan1.0
SMTN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22341,036,635 - 41,060,211 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12243,735,328 - 43,758,712 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02212,105,016 - 12,128,365 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12229,942,889 - 29,966,256 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2229,942,895 - 29,966,256 (+)EnsemblpanPan2panpan1.1
SMTN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12624,085,356 - 24,108,005 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2624,085,382 - 24,108,540 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2623,955,752 - 23,978,245 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02624,468,412 - 24,490,906 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2624,468,434 - 24,490,906 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12624,171,777 - 24,194,301 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02624,433,828 - 24,456,302 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02624,495,094 - 24,517,587 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Smtn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118117,005,130 - 117,028,133 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936755264,570 - 289,260 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936755264,635 - 285,668 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SMTN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1447,879,317 - 47,902,698 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11447,879,317 - 47,902,700 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21450,990,987 - 51,014,394 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SMTN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11913,972,812 - 13,996,124 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1913,974,686 - 13,999,061 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666045112,123,501 - 112,146,815 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Smtn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247477,559,026 - 7,585,154 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247477,559,364 - 7,582,080 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Smtn
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11172,514,913 - 72,535,569 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Smtn
91 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:176
Count of miRNA genes:135
Interacting mature miRNAs:151
Transcripts:ENSRNOT00000026481
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2313089Bss81Bone structure and strength QTL 813.40.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)143802371083023710Rat
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1459848686104848686Rat
1582236Gluco22Glucose level QTL 223.30.0164blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147764007196755654Rat
2300197Scl59Serum cholesterol level QTL 59blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1477914838104348525Rat
70214Niddm28Non-insulin dependent diabetes mellitus QTL 284.06blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)143900944484009444Rat
70153Bp59Blood pressure QTL 593.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)147297021087582095Rat
70187Pancm5Pancreatic morphology QTL 516.7pancreas mass (VT:0010144)pancreas weight to body weight ratio (CMO:0000630)143067446985041098Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1433424686102238540Rat
1582259Gluco23Glucose level QTL 233.10.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1474255551109089856Rat
1582197Gluco27Glucose level QTL 273.40.0006blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)147764007196755654Rat
2313100Bss82Bone structure and strength QTL 8230.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143802371083023710Rat
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1462398852107398852Rat
1582250Gluco26Glucose level QTL 263.30.0009blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1477640071100078267Rat
2317879Alcrsp27Alcohol response QTL 273.30.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1460854936105854936Rat
1641900Alcrsp11Alcohol response QTL 11alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)1474255551109089856Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1411334716100078267Rat
1582255Gluco29Glucose level QTL 293.10.0025blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)147764007196755654Rat
9589034Epfw11Epididymal fat weight QTL 1160.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1459848686104848686Rat
1582209Gluco20Glucose level QTL 203.80.0005blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147764007196755654Rat
2313048Bss84Bone structure and strength QTL 843.10.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143802371083023710Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)144261625899224555Rat
1549834Scl45Serum cholesterol level QTL 455.8blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)146592028399224555Rat
738037Hcas6Hepatocarcinoma susceptibility QTL 62.93liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)143941117087582095Rat
2313084Bss83Bone structure and strength QTL 832.90.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143802371083023710Rat

Markers in Region
RH141196  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21478,398,122 - 78,398,326 (+)MAPPERmRatBN7.2
Rnor_6.01483,754,669 - 83,754,872NCBIRnor6.0
Rnor_5.01484,442,616 - 84,442,819UniSTSRnor5.0
RGSC_v3.41484,160,107 - 84,160,310UniSTSRGSC3.4
Celera1477,310,568 - 77,310,771UniSTS
Cytogenetic Map14q21UniSTS
RH141532  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21478,398,642 - 78,398,835 (+)MAPPERmRatBN7.2
Rnor_6.01483,755,189 - 83,755,381NCBIRnor6.0
Rnor_5.01484,443,136 - 84,443,328UniSTSRnor5.0
RGSC_v3.41484,160,627 - 84,160,819UniSTSRGSC3.4
Celera1477,311,088 - 77,311,280UniSTS
RH 3.4 Map14521.5UniSTS
Cytogenetic Map14q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 162 91 90 59 92 59 6 356 192 11 141 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000026481   ⟹   ENSRNOP00000026481
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1482,622,223 - 82,644,514 (-)Ensembl
mRatBN7.2 Ensembl1478,398,596 - 78,420,886 (-)Ensembl
Rnor_6.0 Ensembl1483,755,142 - 83,776,863 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000077706   ⟹   ENSRNOP00000073901
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1480,678,467 - 80,680,738 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000095950   ⟹   ENSRNOP00000097471
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1482,625,212 - 82,644,514 (-)Ensembl
mRatBN7.2 Ensembl1478,398,596 - 78,414,911 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000098716   ⟹   ENSRNOP00000084768
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1482,622,159 - 82,632,702 (-)Ensembl
mRatBN7.2 Ensembl1478,397,778 - 78,409,779 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000105093   ⟹   ENSRNOP00000094180
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1482,621,375 - 82,644,514 (-)Ensembl
mRatBN7.2 Ensembl1478,397,778 - 78,420,886 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000118432   ⟹   ENSRNOP00000079915
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1482,622,223 - 82,644,514 (-)Ensembl
mRatBN7.2 Ensembl1478,398,596 - 78,420,886 (-)Ensembl
RefSeq Acc Id: NM_001013049   ⟹   NP_001013067
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81482,622,223 - 82,644,514 (-)NCBI
mRatBN7.21478,398,596 - 78,420,886 (-)NCBI
Rnor_6.01483,755,142 - 83,776,863 (-)NCBI
Rnor_5.01484,443,088 - 84,464,813 (-)NCBI
RGSC_v3.41484,160,580 - 84,182,869 (-)RGD
Celera1477,311,041 - 77,333,331 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006251194   ⟹   XP_006251256
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81482,622,223 - 82,644,520 (-)NCBI
mRatBN7.21478,398,595 - 78,420,906 (-)NCBI
Rnor_6.01483,755,141 - 83,776,871 (-)NCBI
Rnor_5.01484,443,088 - 84,464,813 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006251196   ⟹   XP_006251258
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81482,622,223 - 82,644,520 (-)NCBI
mRatBN7.21478,398,596 - 78,420,908 (-)NCBI
Rnor_6.01483,755,141 - 83,776,871 (-)NCBI
Rnor_5.01484,443,088 - 84,464,813 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008770259   ⟹   XP_008768481
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81482,622,223 - 82,644,504 (-)NCBI
mRatBN7.21478,398,595 - 78,420,876 (-)NCBI
Rnor_6.01483,755,141 - 83,776,851 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017599120   ⟹   XP_017454609
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81482,622,223 - 82,644,520 (-)NCBI
mRatBN7.21478,398,595 - 78,420,907 (-)NCBI
Rnor_6.01483,755,141 - 83,776,871 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039091731   ⟹   XP_038947659
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81482,622,223 - 82,644,520 (-)NCBI
mRatBN7.21478,398,595 - 78,420,907 (-)NCBI
RefSeq Acc Id: XM_063272943   ⟹   XP_063129013
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81482,625,437 - 82,644,520 (-)NCBI
RefSeq Acc Id: XM_063272944   ⟹   XP_063129014
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81482,625,437 - 82,644,520 (-)NCBI
RefSeq Acc Id: XM_063272945   ⟹   XP_063129015
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81482,625,437 - 82,634,062 (-)NCBI
RefSeq Acc Id: XR_010057353
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81482,630,813 - 82,644,525 (-)NCBI
RefSeq Acc Id: NP_001013067   ⟸   NM_001013049
- UniProtKB: D4ABA5 (UniProtKB/TrEMBL),   A6IKC3 (UniProtKB/TrEMBL),   A0A8I6ASQ7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006251258   ⟸   XM_006251196
- Peptide Label: isoform X2
- UniProtKB: A0A8I6ASQ7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006251256   ⟸   XM_006251194
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AH70 (UniProtKB/TrEMBL),   A6IKC2 (UniProtKB/TrEMBL),   A0A8I6ASQ7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008768481   ⟸   XM_008770259
- Peptide Label: isoform X8
- UniProtKB: A0A8I6ASQ7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017454609   ⟸   XM_017599120
- Peptide Label: isoform X4
- UniProtKB: A0A8I6ASQ7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000026481   ⟸   ENSRNOT00000026481
RefSeq Acc Id: XP_038947659   ⟸   XM_039091731
- Peptide Label: isoform X5
- UniProtKB: A0A8I6ASQ7 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000073901   ⟸   ENSRNOT00000077706
Ensembl Acc Id: ENSRNOP00000079915   ⟸   ENSRNOT00000118432
Ensembl Acc Id: ENSRNOP00000097471   ⟸   ENSRNOT00000095950
Ensembl Acc Id: ENSRNOP00000094180   ⟸   ENSRNOT00000105093
Ensembl Acc Id: ENSRNOP00000084768   ⟸   ENSRNOT00000098716
RefSeq Acc Id: XP_063129014   ⟸   XM_063272944
- Peptide Label: isoform X6
- UniProtKB: A0A8I5ZNI1 (UniProtKB/TrEMBL),   A0A8I6ASQ7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063129013   ⟸   XM_063272943
- Peptide Label: isoform X3
- UniProtKB: A6IKC3 (UniProtKB/TrEMBL),   D4ABA5 (UniProtKB/TrEMBL),   A0A8I6ASQ7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063129015   ⟸   XM_063272945
- Peptide Label: isoform X7
Protein Domains
Calponin-homology (CH)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K6Q4-F1-model_v2 AlphaFold A0A0G2K6Q4 1-215 view protein structure
AF-D4ABA5-F1-model_v2 AlphaFold D4ABA5 1-921 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699428
Promoter ID:EPDNEW_R9953
Type:multiple initiation site
Name:Smtn_1
Description:smoothelin
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01483,776,850 - 83,776,910EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310216 AgrOrtholog
BioCyc Gene G2FUF-15223 BioCyc
Ensembl Genes ENSRNOG00000019451 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00000054319 Ensembl
Ensembl Transcript ENSRNOT00000026481 ENTREZGENE
  ENSRNOT00000026481.5 UniProtKB/TrEMBL
  ENSRNOT00000095950 ENTREZGENE
  ENSRNOT00000095950.2 UniProtKB/TrEMBL
  ENSRNOT00000098716.2 UniProtKB/TrEMBL
  ENSRNOT00000105093 ENTREZGENE
  ENSRNOT00000105093.2 UniProtKB/TrEMBL
  ENSRNOT00000118432 ENTREZGENE
  ENSRNOT00000118432.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.418.10 UniProtKB/TrEMBL
InterPro Calponin-like_dom_sf UniProtKB/TrEMBL
  CH-domain UniProtKB/TrEMBL
  F-actin_Monoox_Mical UniProtKB/TrEMBL
  Smoothelin UniProtKB/TrEMBL
KEGG Report rno:289734 UniProtKB/TrEMBL
NCBI Gene 289734 ENTREZGENE
PANTHER CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED UniProtKB/TrEMBL
  SMOOTHELIN UniProtKB/TrEMBL
Pfam PF00307 UniProtKB/TrEMBL
  Smoothelin UniProtKB/TrEMBL
PhenoGen Smtn PhenoGen
PROSITE PS50021 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000019451 RatGTEx
  ENSRNOG00000054319 RatGTEx
SMART SM00033 UniProtKB/TrEMBL
Superfamily-SCOP Calponin-homology UniProtKB/TrEMBL
UniProt A0A8I5ZNI1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A098_RAT UniProtKB/TrEMBL
  A0A8I6AH70 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ASQ7 ENTREZGENE, UniProtKB/TrEMBL
  A6IKC2 ENTREZGENE, UniProtKB/TrEMBL
  A6IKC3 ENTREZGENE, UniProtKB/TrEMBL
  D4ABA5 ENTREZGENE, UniProtKB/TrEMBL
  Q63ZV4_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Smtn  smoothelin  LOC103690128  smoothelin-like  Data merged from RGD:9196123 737654 PROVISIONAL
2014-08-25 LOC103690128  smoothelin-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-12-06 Smtn  smoothelin  Smtn_predicted  smoothelin (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Smtn_predicted  smoothelin (predicted)      Symbol and Name status set to approved 70820 APPROVED