Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Kif16b | Rat | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of KIF16B mRNA] | CTD | PMID:31150632 | Kif16b | Rat | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | KIF16B (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of KIF16B mRNA | CTD | PMID:22079256 | Kif16b | Rat | 1,2-dichloroethane | decreases expression | ISO | Kif16b (Mus musculus) | 6480464 | ethylene dichloride results in decreased expression of KIF16B mRNA | CTD | PMID:28960355 | Kif16b | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Kif16b (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in decreased expression of KIF16B mRNA | CTD | PMID:22206623 | Kif16b | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Kif16b (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of KIF16B mRNA] | CTD | PMID:22206623 | Kif16b | Rat | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2,4-dinitrotoluene affects the expression of KIF16B mRNA | CTD | PMID:21346803 | Kif16b | Rat | 2-hydroxypropanoic acid | decreases expression | ISO | KIF16B (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of KIF16B mRNA | CTD | PMID:30851411 | Kif16b | Rat | 2-palmitoylglycerol | increases expression | ISO | KIF16B (Homo sapiens) | 6480464 | 2-palmitoylglycerol results in increased expression of KIF16B mRNA | CTD | PMID:37199045 | Kif16b | Rat | 4,4'-diaminodiphenylmethane | decreases expression | EXP | | 6480464 | 4,4'-diaminodiphenylmethane results in decreased expression of KIF16B mRNA | CTD | PMID:30723492 | Kif16b | Rat | 4,4'-sulfonyldiphenol | decreases expression | ISO | Kif16b (Mus musculus) | 6480464 | bisphenol S results in decreased expression of KIF16B mRNA | CTD | PMID:39298647 | Kif16b | Rat | acrylamide | decreases expression | EXP | | 6480464 | Acrylamide results in decreased expression of KIF16B mRNA | CTD | PMID:28959563 | Kif16b | Rat | aflatoxin B1 | decreases expression | ISO | Kif16b (Mus musculus) | 6480464 | Aflatoxin B1 results in decreased expression of KIF16B mRNA | CTD | PMID:19770486 | Kif16b | Rat | aflatoxin B1 | decreases expression | ISO | KIF16B (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased expression of KIF16B mRNA | CTD | PMID:21632981|PMID:21641981|PMID:22100608 | Kif16b | Rat | amiodarone | increases expression | ISO | KIF16B (Homo sapiens) | 6480464 | Amiodarone results in increased expression of KIF16B mRNA | CTD | PMID:19774075 | Kif16b | Rat | antirheumatic drug | increases expression | ISO | KIF16B (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of KIF16B mRNA | CTD | PMID:24449571 | Kif16b | Rat | aristolochic acid A | decreases expression | ISO | KIF16B (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of KIF16B mRNA | CTD | PMID:33212167 | Kif16b | Rat | arsenite(3-) | multiple interactions | ISO | KIF16B (Homo sapiens) | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to KIF16B mRNA] | CTD | PMID:32406909 | Kif16b | Rat | atrazine | affects methylation | EXP | | 6480464 | Atrazine affects the methylation of KIF16B gene | CTD | PMID:28931070 | Kif16b | Rat | benzo[a]pyrene | decreases expression | ISO | Kif16b (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of KIF16B mRNA | CTD | PMID:19770486 | Kif16b | Rat | benzo[a]pyrene | increases methylation | ISO | KIF16B (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of KIF16B promoter | CTD | PMID:27901495 | Kif16b | Rat | benzo[a]pyrene | decreases expression | ISO | KIF16B (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of KIF16B mRNA | CTD | PMID:20064835|PMID:20106945|PMID:21632981|PMID:22316170|PMID:26238291 | Kif16b | Rat | benzo[a]pyrene | affects expression | ISO | KIF16B (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the expression of KIF16B mRNA | CTD | PMID:21714911 | Kif16b | Rat | bis(2-chloroethyl) sulfide | multiple interactions | ISO | Kif16b (Mus musculus) | 6480464 | Dimercaprol inhibits the reaction [Mustard Gas results in decreased expression of KIF16B mRNA] | CTD | PMID:16377760 | Kif16b | Rat | bis(2-chloroethyl) sulfide | decreases expression | ISO | Kif16b (Mus musculus) | 6480464 | Mustard Gas results in decreased expression of KIF16B mRNA | CTD | PMID:16377760 | Kif16b | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of KIF16B mRNA | CTD | PMID:25181051 | Kif16b | Rat | bisphenol A | increases expression | ISO | KIF16B (Homo sapiens) | 6480464 | bisphenol A results in increased expression of KIF16B protein | CTD | PMID:32981897 | Kif16b | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of KIF16B mRNA | CTD | PMID:34947998 | Kif16b | Rat | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of KIF16B gene | CTD | PMID:28505145 | Kif16b | Rat | bisphenol F | increases expression | ISO | Kif16b (Mus musculus) | 6480464 | bisphenol F results in increased expression of KIF16B mRNA | CTD | PMID:38685157 | Kif16b | Rat | Butylbenzyl phthalate | decreases methylation | ISO | Kif16b (Mus musculus) | 6480464 | butylbenzyl phthalate results in decreased methylation of KIF16B intron | CTD | PMID:28392331 | Kif16b | Rat | cadmium dichloride | decreases expression | ISO | KIF16B (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of KIF16B mRNA | CTD | PMID:38568856 | Kif16b | Rat | caffeine | affects phosphorylation | ISO | KIF16B (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of KIF16B protein | CTD | PMID:35688186 | Kif16b | Rat | carbon nanotube | decreases expression | ISO | Kif16b (Mus musculus) | 6480464 | Nanotubes, Carbon analog results in decreased expression of KIF16B mRNA; Nanotubes, Carbon results in decreased more ... | CTD | PMID:25554681|PMID:25620056 | Kif16b | Rat | copper(II) sulfate | decreases expression | ISO | KIF16B (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of KIF16B mRNA | CTD | PMID:19549813 | Kif16b | Rat | crocidolite asbestos | decreases expression | ISO | Kif16b (Mus musculus) | 6480464 | Asbestos, Crocidolite results in decreased expression of KIF16B mRNA | CTD | PMID:29279043 | Kif16b | Rat | cyclosporin A | increases expression | ISO | KIF16B (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of KIF16B mRNA | CTD | PMID:20106945 | Kif16b | Rat | Dibutyl phosphate | affects expression | ISO | KIF16B (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of KIF16B mRNA | CTD | PMID:37042841 | Kif16b | Rat | dimercaprol | multiple interactions | ISO | Kif16b (Mus musculus) | 6480464 | Dimercaprol inhibits the reaction [Mustard Gas results in decreased expression of KIF16B mRNA] | CTD | PMID:16377760 | Kif16b | Rat | dorsomorphin | multiple interactions | ISO | KIF16B (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Kif16b | Rat | doxorubicin | decreases expression | ISO | KIF16B (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of KIF16B mRNA | CTD | PMID:29803840 | Kif16b | Rat | entinostat | increases expression | ISO | KIF16B (Homo sapiens) | 6480464 | entinostat results in increased expression of KIF16B mRNA | CTD | PMID:27188386 | Kif16b | Rat | folic acid | multiple interactions | ISO | Kif16b (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of KIF16B mRNA] | CTD | PMID:22206623 | Kif16b | Rat | FR900359 | increases phosphorylation | ISO | KIF16B (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of KIF16B protein | CTD | PMID:37730182 | Kif16b | Rat | manganese atom | multiple interactions | ISO | KIF16B (Homo sapiens) | 6480464 | [manganese chloride results in increased abundance of Manganese] which results in decreased expression of KIF16B more ... | CTD | PMID:39836092 | Kif16b | Rat | manganese(0) | multiple interactions | ISO | KIF16B (Homo sapiens) | 6480464 | [manganese chloride results in increased abundance of Manganese] which results in decreased expression of KIF16B more ... | CTD | PMID:39836092 | Kif16b | Rat | manganese(II) chloride | multiple interactions | ISO | KIF16B (Homo sapiens) | 6480464 | [manganese chloride results in increased abundance of Manganese] which results in decreased expression of KIF16B more ... | CTD | PMID:39836092 | Kif16b | Rat | methapyrilene | decreases expression | EXP | | 6480464 | Methapyrilene results in decreased expression of KIF16B mRNA | CTD | PMID:30467583 | Kif16b | Rat | methylmercury chloride | decreases expression | ISO | KIF16B (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of KIF16B mRNA | CTD | PMID:28001369 | Kif16b | Rat | nickel sulfate | decreases expression | ISO | KIF16B (Homo sapiens) | 6480464 | nickel sulfate results in decreased expression of KIF16B mRNA | CTD | PMID:22714537 | Kif16b | Rat | paracetamol | decreases expression | ISO | KIF16B (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of KIF16B mRNA | CTD | PMID:21420995 | Kif16b | Rat | pirinixic acid | increases expression | ISO | Kif16b (Mus musculus) | 6480464 | pirinixic acid results in increased expression of KIF16B mRNA | CTD | PMID:18301758 | Kif16b | Rat | potassium chromate | multiple interactions | ISO | KIF16B (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of KIF16B mRNA | CTD | PMID:22079256 | Kif16b | Rat | potassium chromate | decreases expression | ISO | KIF16B (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of KIF16B mRNA | CTD | PMID:22079256 | Kif16b | Rat | propiconazole | increases expression | ISO | Kif16b (Mus musculus) | 6480464 | propiconazole results in increased expression of KIF16B mRNA | CTD | PMID:21278054 | Kif16b | Rat | quercetin | decreases expression | ISO | KIF16B (Homo sapiens) | 6480464 | Quercetin results in decreased expression of KIF16B mRNA | CTD | PMID:21632981 | Kif16b | Rat | quercetin | decreases phosphorylation | ISO | KIF16B (Homo sapiens) | 6480464 | Quercetin results in decreased phosphorylation of KIF16B protein | CTD | PMID:35688186 | Kif16b | Rat | rac-lactic acid | decreases expression | ISO | KIF16B (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of KIF16B mRNA | CTD | PMID:30851411 | Kif16b | Rat | SB 431542 | multiple interactions | ISO | KIF16B (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Kif16b | Rat | sodium arsenite | decreases expression | ISO | KIF16B (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of KIF16B mRNA | CTD | PMID:22714537 | Kif16b | Rat | sodium dichromate | affects expression | EXP | | 6480464 | sodium bichromate affects the expression of KIF16B mRNA | CTD | PMID:22110744 | Kif16b | Rat | Soman | decreases expression | EXP | | 6480464 | Soman results in decreased expression of KIF16B mRNA | CTD | PMID:19281266 | Kif16b | Rat | T-2 toxin | decreases expression | EXP | | 6480464 | T-2 Toxin results in decreased expression of KIF16B mRNA | CTD | PMID:26141394 | Kif16b | Rat | temozolomide | decreases expression | ISO | KIF16B (Homo sapiens) | 6480464 | Temozolomide results in decreased expression of KIF16B mRNA | CTD | PMID:31758290 | Kif16b | Rat | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of KIF16B mRNA] | CTD | PMID:31150632 | Kif16b | Rat | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of KIF16B mRNA | CTD | PMID:31150632 | Kif16b | Rat | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of KIF16B mRNA | CTD | PMID:34492290 | Kif16b | Rat | trichostatin A | increases expression | ISO | KIF16B (Homo sapiens) | 6480464 | trichostatin A results in increased expression of KIF16B mRNA | CTD | PMID:24935251 | Kif16b | Rat | triphenyl phosphate | affects expression | ISO | KIF16B (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of KIF16B mRNA | CTD | PMID:37042841 | Kif16b | Rat | valproic acid | affects expression | ISO | KIF16B (Homo sapiens) | 6480464 | Valproic Acid affects the expression of KIF16B mRNA | CTD | PMID:25979313 | Kif16b | Rat | valproic acid | multiple interactions | ISO | KIF16B (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Kif16b | Rat | valproic acid | increases expression | ISO | KIF16B (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of KIF16B mRNA | CTD | PMID:23179753|PMID:24383497|PMID:24935251|PMID:26272509 | Kif16b | Rat | vinclozolin | increases expression | EXP | | 6480464 | vinclozolin results in increased expression of KIF16B mRNA | CTD | PMID:23034163 | Kif16b | Rat | vitamin E | decreases expression | ISO | KIF16B (Homo sapiens) | 6480464 | Vitamin E results in decreased expression of KIF16B mRNA | CTD | PMID:19244175 | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















