Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | ISO | Kif16b (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of KIF16B mRNA] | CTD | PMID:31150632 | (-)-epigallocatechin 3-gallate | multiple interactions | EXP | | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of KIF16B mRNA | CTD | PMID:22079256 | 1,2-dichloroethane | decreases expression | ISO | Kif16b (Mus musculus) | 6480464 | ethylene dichloride results in decreased expression of KIF16B mRNA | CTD | PMID:28960355 | 1,2-dimethylhydrazine | decreases expression | ISO | Kif16b (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of KIF16B mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | multiple interactions | ISO | Kif16b (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in decreased expression of KIF16B mRNA] | CTD | PMID:22206623 | 2,4-dinitrotoluene | affects expression | ISO | Kif16b (Rattus norvegicus) | 6480464 | 2 and 4-dinitrotoluene affects the expression of KIF16B mRNA | CTD | PMID:21346803 | 2-hydroxypropanoic acid | decreases expression | EXP | | 6480464 | Lactic Acid results in decreased expression of KIF16B mRNA | CTD | PMID:30851411 | 2-palmitoylglycerol | increases expression | EXP | | 6480464 | 2-palmitoylglycerol results in increased expression of KIF16B mRNA | CTD | PMID:37199045 | 4,4'-diaminodiphenylmethane | decreases expression | ISO | Kif16b (Rattus norvegicus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in decreased expression of KIF16B mRNA | CTD | PMID:30723492 | acrylamide | decreases expression | ISO | Kif16b (Rattus norvegicus) | 6480464 | Acrylamide results in decreased expression of KIF16B mRNA | CTD | PMID:28959563 | aflatoxin B1 | decreases expression | ISO | Kif16b (Mus musculus) | 6480464 | Aflatoxin B1 results in decreased expression of KIF16B mRNA | CTD | PMID:19770486 | aflatoxin B1 | decreases expression | EXP | | 6480464 | Aflatoxin B1 results in decreased expression of KIF16B mRNA | CTD | PMID:21632981 more ... | amiodarone | increases expression | EXP | | 6480464 | Amiodarone results in increased expression of KIF16B mRNA | CTD | PMID:19774075 | antirheumatic drug | increases expression | EXP | | 6480464 | Antirheumatic Agents results in increased expression of KIF16B mRNA | CTD | PMID:24449571 | aristolochic acid A | decreases expression | EXP | | 6480464 | aristolochic acid I results in decreased expression of KIF16B mRNA | CTD | PMID:33212167 | arsenite(3-) | multiple interactions | EXP | | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to KIF16B mRNA] | CTD | PMID:32406909 | atrazine | affects methylation | ISO | Kif16b (Rattus norvegicus) | 6480464 | Atrazine affects the methylation of KIF16B gene | CTD | PMID:28931070 | benzo[a]pyrene | decreases expression | ISO | Kif16b (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of KIF16B mRNA | CTD | PMID:19770486 | benzo[a]pyrene | increases methylation | EXP | | 6480464 | Benzo(a)pyrene results in increased methylation of KIF16B promoter | CTD | PMID:27901495 | benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzo(a)pyrene results in decreased expression of KIF16B mRNA | CTD | PMID:20064835 more ... | benzo[a]pyrene | affects expression | EXP | | 6480464 | Benzo(a)pyrene affects the expression of KIF16B mRNA | CTD | PMID:21714911 | bis(2-chloroethyl) sulfide | multiple interactions | ISO | Kif16b (Mus musculus) | 6480464 | Dimercaprol inhibits the reaction [Mustard Gas results in decreased expression of KIF16B mRNA] | CTD | PMID:16377760 | bis(2-chloroethyl) sulfide | decreases expression | ISO | Kif16b (Mus musculus) | 6480464 | Mustard Gas results in decreased expression of KIF16B mRNA | CTD | PMID:16377760 | bisphenol A | increases expression | ISO | Kif16b (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of KIF16B mRNA | CTD | PMID:25181051 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of KIF16B protein | CTD | PMID:32981897 | bisphenol A | decreases expression | ISO | Kif16b (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of KIF16B mRNA | CTD | PMID:34947998 | bisphenol A | increases methylation | ISO | Kif16b (Rattus norvegicus) | 6480464 | bisphenol A results in increased methylation of KIF16B gene | CTD | PMID:28505145 | caffeine | affects phosphorylation | EXP | | 6480464 | Caffeine affects the phosphorylation of KIF16B protein | CTD | PMID:35688186 | carbon nanotube | decreases expression | ISO | Kif16b (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 and PMID:25620056 | copper(II) sulfate | decreases expression | EXP | | 6480464 | Copper Sulfate results in decreased expression of KIF16B mRNA | CTD | PMID:19549813 | crocidolite asbestos | decreases expression | ISO | Kif16b (Mus musculus) | 6480464 | Asbestos and Crocidolite results in decreased expression of KIF16B mRNA | CTD | PMID:29279043 | cyclosporin A | increases expression | EXP | | 6480464 | Cyclosporine results in increased expression of KIF16B mRNA | CTD | PMID:20106945 | dimercaprol | multiple interactions | ISO | Kif16b (Mus musculus) | 6480464 | Dimercaprol inhibits the reaction [Mustard Gas results in decreased expression of KIF16B mRNA] | CTD | PMID:16377760 | dorsomorphin | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KIF16B mRNA | CTD | PMID:27188386 | doxorubicin | decreases expression | EXP | | 6480464 | Doxorubicin results in decreased expression of KIF16B mRNA | CTD | PMID:29803840 | entinostat | increases expression | EXP | | 6480464 | entinostat results in increased expression of KIF16B mRNA | CTD | PMID:27188386 | folic acid | multiple interactions | ISO | Kif16b (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in decreased expression of KIF16B mRNA] | CTD | PMID:22206623 | FR900359 | increases phosphorylation | EXP | | 6480464 | FR900359 results in increased phosphorylation of KIF16B protein | CTD | PMID:37730182 | methapyrilene | decreases expression | ISO | Kif16b (Rattus norvegicus) | 6480464 | Methapyrilene results in decreased expression of KIF16B mRNA | CTD | PMID:30467583 | methylmercury chloride | decreases expression | EXP | | 6480464 | methylmercuric chloride results in decreased expression of KIF16B mRNA | CTD | PMID:28001369 | nickel sulfate | decreases expression | EXP | | 6480464 | nickel sulfate results in decreased expression of KIF16B mRNA | CTD | PMID:22714537 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of KIF16B mRNA | CTD | PMID:21420995 | pirinixic acid | increases expression | ISO | Kif16b (Mus musculus) | 6480464 | pirinixic acid results in increased expression of KIF16B mRNA | CTD | PMID:18301758 | potassium chromate | multiple interactions | EXP | | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of KIF16B mRNA | CTD | PMID:22079256 | potassium chromate | decreases expression | EXP | | 6480464 | potassium chromate(VI) results in decreased expression of KIF16B mRNA | CTD | PMID:22079256 | propiconazole | increases expression | ISO | Kif16b (Mus musculus) | 6480464 | propiconazole results in increased expression of KIF16B mRNA | CTD | PMID:21278054 | quercetin | decreases expression | EXP | | 6480464 | Quercetin results in decreased expression of KIF16B mRNA | CTD | PMID:21632981 | quercetin | decreases phosphorylation | EXP | | 6480464 | Quercetin results in decreased phosphorylation of KIF16B protein | CTD | PMID:35688186 | rac-lactic acid | decreases expression | EXP | | 6480464 | Lactic Acid results in decreased expression of KIF16B mRNA | CTD | PMID:30851411 | SB 431542 | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KIF16B mRNA | CTD | PMID:27188386 | sodium arsenite | decreases expression | EXP | | 6480464 | sodium arsenite results in decreased expression of KIF16B mRNA | CTD | PMID:22714537 | sodium dichromate | affects expression | ISO | Kif16b (Rattus norvegicus) | 6480464 | sodium bichromate affects the expression of KIF16B mRNA | CTD | PMID:22110744 | Soman | decreases expression | ISO | Kif16b (Rattus norvegicus) | 6480464 | Soman results in decreased expression of KIF16B mRNA | CTD | PMID:19281266 | T-2 toxin | decreases expression | ISO | Kif16b (Rattus norvegicus) | 6480464 | T-2 Toxin results in decreased expression of KIF16B mRNA | CTD | PMID:26141394 | temozolomide | decreases expression | EXP | | 6480464 | Temozolomide results in decreased expression of KIF16B mRNA | CTD | PMID:31758290 | tetrachloromethane | multiple interactions | ISO | Kif16b (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of KIF16B mRNA] | CTD | PMID:31150632 | tetrachloromethane | decreases expression | ISO | Kif16b (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in decreased expression of KIF16B mRNA | CTD | PMID:31150632 | thioacetamide | decreases expression | ISO | Kif16b (Rattus norvegicus) | 6480464 | Thioacetamide results in decreased expression of KIF16B mRNA | CTD | PMID:34492290 | trichostatin A | increases expression | EXP | | 6480464 | trichostatin A results in increased expression of KIF16B mRNA | CTD | PMID:24935251 | valproic acid | affects expression | EXP | | 6480464 | Valproic Acid affects the expression of KIF16B mRNA | CTD | PMID:25979313 | valproic acid | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KIF16B mRNA | CTD | PMID:27188386 | valproic acid | increases expression | EXP | | 6480464 | Valproic Acid results in increased expression of KIF16B mRNA | CTD | PMID:23179753 more ... | vinclozolin | increases expression | ISO | Kif16b (Rattus norvegicus) | 6480464 | vinclozolin results in increased expression of KIF16B mRNA | CTD | PMID:23034163 | vitamin E | decreases expression | EXP | | 6480464 | Vitamin E results in decreased expression of KIF16B mRNA | CTD | PMID:19244175 | | 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Gene Ontology Annotations Click to see Annotation Detail View
Biological Process
Cellular Component
Molecular Function
Phenotype Annotations Click to see Annotation Detail View
Imported Human Phenotype Annotations - ClinVar
Disease Annotations
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Gene-Chemical Interaction Annotations
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Gene Ontology Annotations
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Biological Process
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Cellular Component
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Molecular Function
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Phenotype Annotations
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References
References - curated
| # | Reference Title | Reference Citation |
| 1. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 2. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
Additional References at PubMed
| PMID:10997877 | PMID:11780052 | PMID:12461558 | PMID:12477932 | PMID:14702039 | PMID:15489334 | PMID:15882625 | PMID:16084724 | PMID:16782399 | PMID:17203973 | PMID:17641687 | PMID:18445686 |
| PMID:21139019 | PMID:21873635 | PMID:22357949 | PMID:22449649 | PMID:22558309 | PMID:23006423 | PMID:23749212 | PMID:26496610 | PMID:27107012 | PMID:28514442 | PMID:29507755 | PMID:29568061 |
| PMID:29736960 | PMID:29778605 | PMID:30639242 | PMID:30659120 | PMID:31056421 | PMID:31182584 | PMID:31618441 | PMID:32296183 | PMID:32807901 | PMID:32877691 | PMID:33957083 | PMID:33961781 |
| PMID:34079125 | PMID:34369648 | PMID:34432599 | PMID:34709727 | PMID:35384245 | PMID:35944360 | PMID:37689310 | PMID:37696580 |
Genomics
Comparative Map Data
| KIF16B (Homo sapiens - human) |
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| Kif16b (Mus musculus - house mouse) |
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| Kif16b (Rattus norvegicus - Norway rat) |
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| Kif16b (Chinchilla lanigera - long-tailed chinchilla) |
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| KIF16B (Pan paniscus - bonobo/pygmy chimpanzee) |
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| KIF16B (Canis lupus familiaris - dog) |
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| Kif16b (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| KIF16B (Sus scrofa - pig) |
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| KIF16B (Chlorocebus sabaeus - green monkey) |
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| Kif16b (Heterocephalus glaber - naked mole-rat) |
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Variants
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Variants in KIF16B
95 total Variants 
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