Fktn (fukutin) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Pathways
Gene: Fktn (fukutin) Rattus norvegicus
Analyze
Symbol: Fktn
Name: fukutin
RGD ID: 1310087
Description: Predicted to enable phosphotransferase activity, for other substituted phosphate groups. Predicted to be involved in several processes, including negative regulation of JNK cascade; protein O-linked glycosylation via mannose; and protein glycosylation. Predicted to act upstream of or within basement membrane organization; brain development; and skeletal muscle fiber differentiation. Predicted to be located in cis-Golgi network; endoplasmic reticulum; and nucleus. Predicted to be active in Golgi membrane. Human ortholog(s) of this gene implicated in dilated cardiomyopathy (multiple) and muscular dystrophy (multiple). Orthologous to human FKTN (fukutin); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Fcmd; Fukuyama type congenital muscular dystrophy (fukutin); Fukuyama type congenital muscular dystrophy homolog; Fukuyama type congenital muscular dystrophy homolog (human); LOC362520; ribitol-5-phosphate transferase FKTN
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8573,134,746 - 73,191,772 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl573,135,361 - 73,189,181 (+)EnsemblGRCr8
mRatBN7.2568,339,803 - 68,396,412 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl568,340,028 - 68,396,409 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx570,227,762 - 70,281,805 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0572,044,733 - 72,098,826 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0572,016,575 - 72,070,620 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0570,522,001 - 70,578,270 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl570,528,688 - 70,578,273 (+)Ensemblrn6Rnor6.0
Rnor_5.0574,697,518 - 74,754,106 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4571,155,051 - 71,208,525 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera567,234,078 - 67,287,987 (+)NCBICelera
RGSC_v3.1571,168,040 - 71,211,945 (+)NCBI
Cytogenetic Map5q24NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Founder Fukutin mutation causes Walker-Warburg syndrome in four Ashkenazi Jewish families. Chang W, etal., Prenat Diagn. 2009 Jun;29(6):560-9. doi: 10.1002/pd.2238.
2. Development of rabbit monoclonal antibodies for detection of alpha-dystroglycan in normal and dystrophic tissue. Fortunato MJ, etal., PLoS One. 2014 May 13;9(5):e97567. doi: 10.1371/journal.pone.0097567. eCollection 2014.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Fukutin gene mutations in steroid-responsive limb girdle muscular dystrophy. Godfrey C, etal., Ann Neurol. 2006 Nov;60(5):603-10.
6. Selective deficiency of alpha-dystroglycan in Fukuyama-type congenital muscular dystrophy. Hayashi YK, etal., Neurology. 2001 Jul 10;57(1):115-21.
7. An ancient retrotransposal insertion causes Fukuyama-type congenital muscular dystrophy. Kobayashi K, etal., Nature. 1998 Jul 23;394(6691):388-92.
8. Novel mutations and genotype-phenotype relationships in 107 families with Fukuyama-type congenital muscular dystrophy (FCMD). Kondo-Iida E, etal., Hum Mol Genet. 1999 Nov;8(12):2303-9.
9. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
10. Fukutin gene mutations cause dilated cardiomyopathy with minimal muscle weakness. Murakami T, etal., Ann Neurol. 2006 Nov;60(5):597-602.
11. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
12. Further evidence of Fukutin mutations as a cause of childhood onset limb-girdle muscular dystrophy without mental retardation. Puckett RL, etal., Neuromuscul Disord. 2009 May;19(5):352-6. doi: 10.1016/j.nmd.2009.03.001. Epub 2009 Apr 1.
13. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
14. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
15. Comprehensive gene review and curation RGD comprehensive gene curation
16. Fukutin protein is expressed in neurons of the normal developing human brain but is reduced in Fukuyama-type congenital muscular dystrophy brain. Saito Y, etal., Ann Neurol. 2000 Jun;47(6):756-64.
17. Four Caucasian patients with mutations in the fukutin gene and variable clinical phenotype. Vuillaumier-Barrot S, etal., Neuromuscul Disord. 2009 Mar;19(3):182-8. doi: 10.1016/j.nmd.2008.12.005.
18. Fukutin mutations in non-Japanese patients with congenital muscular dystrophy: less severe mutations predominate in patients with a non-Walker-Warburg phenotype. Yis U, etal., Neuromuscul Disord. 2011 Jan;21(1):20-30. doi: 10.1016/j.nmd.2010.08.007. Epub 2010 Oct 18.
Additional References at PubMed
PMID:12471058   PMID:15213246   PMID:17034757   PMID:18808525   PMID:25279699  


Genomics

Comparative Map Data
Fktn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8573,134,746 - 73,191,772 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl573,135,361 - 73,189,181 (+)EnsemblGRCr8
mRatBN7.2568,339,803 - 68,396,412 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl568,340,028 - 68,396,409 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx570,227,762 - 70,281,805 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0572,044,733 - 72,098,826 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0572,016,575 - 72,070,620 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0570,522,001 - 70,578,270 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl570,528,688 - 70,578,273 (+)Ensemblrn6Rnor6.0
Rnor_5.0574,697,518 - 74,754,106 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4571,155,051 - 71,208,525 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera567,234,078 - 67,287,987 (+)NCBICelera
RGSC_v3.1571,168,040 - 71,211,945 (+)NCBI
Cytogenetic Map5q24NCBI
FKTN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389105,558,130 - 105,641,118 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9105,558,122 - 105,653,820 (+)Ensemblhg38GRCh38
GRCh379108,320,411 - 108,403,399 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369107,360,232 - 107,443,220 (+)NCBIBuild 36Build 36hg18NCBI36
Build 349105,399,978 - 105,482,953NCBI
Celera978,825,571 - 78,908,566 (+)NCBICelera
Cytogenetic Map9q31.2NCBI
HuRef977,921,830 - 78,004,880 (+)NCBIHuRef
CHM1_19108,467,406 - 108,550,392 (+)NCBICHM1_1
T2T-CHM13v2.09117,732,799 - 117,815,798 (+)NCBIT2T-CHM13v2.0
Fktn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39453,713,745 - 53,765,785 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl453,713,998 - 53,777,890 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38453,714,107 - 53,765,785 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl453,713,998 - 53,777,890 (+)Ensemblmm10GRCm38
MGSCv37453,727,054 - 53,776,143 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36453,735,282 - 53,784,371 (+)NCBIMGSCv36mm8
Celera453,671,147 - 53,720,238 (+)NCBICelera
Cytogenetic Map4B2NCBI
cM Map428.74NCBI
Fktn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541920,933,662 - 20,994,793 (-)Ensembl
ChiLan1.0NW_00495541920,933,662 - 20,994,793 (-)NCBIChiLan1.0ChiLan1.0
FKTN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21133,736,875 - 33,835,805 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1933,739,744 - 33,839,021 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0976,723,071 - 76,821,611 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19104,849,447 - 104,926,414 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9104,849,496 - 104,925,422 (+)EnsemblpanPan2panpan1.1
FKTN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11161,394,002 - 61,462,056 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1161,405,034 - 61,461,396 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1159,854,900 - 59,922,736 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01162,541,606 - 62,598,262 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1162,530,493 - 62,597,602 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11161,048,756 - 61,131,662 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01161,079,051 - 61,135,687 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01161,760,632 - 61,835,969 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Fktn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947176,585,787 - 176,685,702 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365596,581,622 - 6,581,948 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0 EnsemblNW_0049365596,619,531 - 6,670,727 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365596,612,318 - 6,680,690 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FKTN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1246,853,166 - 246,916,644 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11246,852,387 - 246,916,650 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21276,542,569 - 276,576,326 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FKTN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11233,872,165 - 33,964,105 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1233,900,362 - 33,953,377 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660358,677,300 - 8,770,035 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fktn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247585,792,514 - 5,877,709 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247585,750,804 - 5,877,797 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Fktn
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1197,478,841 - 97,530,576 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Fktn
292 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:176
Count of miRNA genes:119
Interacting mature miRNAs:152
Transcripts:ENSRNOT00000036799
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578776Stresp18Stress response QTL 182.9thymus mass (VT:0004954)thymus wet weight (CMO:0000855)53275164977751649Rat
1298067Scl15Serum cholesterol level QTL 154.80.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53801167083011670Rat
1300115Hrtrt7Heart rate QTL 72.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)55266537294894052Rat
6907115Mcs29Mammary carcinoma susceptibility QTL 29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)53800433183004331Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)544924861153890773Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)52367149379046465Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)538207390136631402Rat
61386Bp49Blood pressure QTL 4916.6cerebrum integrity trait (VT:0010549)brain infarction volume (CMO:0001013)565089051103648916Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)548523123134369373Rat
1598807Glom12Glomerulus QTL 122.7kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)53801167083011670Rat
1302786Kidm8Kidney mass QTL 828.15kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)53801167083011670Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)565089051166764498Rat
1331782Rf36Renal function QTL 363.296kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)539019942102105896Rat
6903292Stl28Serum triglyceride level QTL 282.60.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)53331167378311673Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)551657967166600247Rat
1578767Stresp17Stress response QTL 174.30.01blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)53275164977751649Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555124766172190305Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)53998594884985948Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)5692228281330203Rat
6903306Scl35Serum cholesterol QTL 352.60.0073blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53331167378311673Rat
7394708Emca11Estrogen-induced mammary cancer QTL 11mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)573176602118176602Rat
1576317Eutr2Estrogen induced uterine response QTL 20.01uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)53952692484526924Rat
1331773Scl26Serum cholesterol level QTL 263.065blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)54852312391770353Rat
1578673Bmd13Bone mineral density QTL 134.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)569474415114474415Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)560601597137492949Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906491770353Rat
61359EaexExperimental allergic encephalomyelitis QTL x3nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)560511627105511627Rat
8662454Vetf3Vascular elastic tissue fragility QTL 327.4artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)5706553574335773Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)536460764136631402Rat
61426Scl2Serum cholesterol level QTL 27.30.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)564589016109589016Rat
2290005Mcs24Mammary carcinoma susceptibility QTL 24mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)569835120114835120Rat
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906487027358Rat
2306971Anxrr21Anxiety related response QTL 219.47fear/anxiety-related behavior trait (VT:1000241)number of entries into a discrete space in an experimental apparatus (CMO:0000960)570969494136328156Rat
2316954Rf57Renal function QTL 570kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)56458901693503770Rat
2316959Gluco59Glucose level QTL 594.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)556546393101546393Rat
2316957Pur21Proteinuria QTL 216.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)56458901691762830Rat

Markers in Region
RH135333  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2568,339,107 - 68,339,304 (+)MAPPERmRatBN7.2
Rnor_6.0570,521,306 - 70,521,502NCBIRnor6.0
Rnor_5.0574,697,162 - 74,697,358UniSTSRnor5.0
RGSC_v3.4571,154,357 - 71,154,553UniSTSRGSC3.4
Celera567,233,384 - 67,233,580UniSTS
RH 3.4 Map5466.8UniSTS
Cytogenetic Map5q24UniSTS
RH140020  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2568,393,312 - 68,393,493 (+)MAPPERmRatBN7.2
Rnor_6.0570,575,169 - 70,575,349NCBIRnor6.0
Rnor_5.0574,751,005 - 74,751,185UniSTSRnor5.0
RGSC_v3.4571,208,015 - 71,208,195UniSTSRGSC3.4
Celera567,287,477 - 67,287,657UniSTS
RH 3.4 Map5467.4UniSTS
Cytogenetic Map5q24UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001108667 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001437003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001437005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001437006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001437007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001437008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001437010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001437011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001437012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001437013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001437014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006238166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006238168 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006238169 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008763712 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008763713 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008763714 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008763715 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039110244 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039110247 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039110248 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039110249 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287921 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287923 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287924 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287925 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287926 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287927 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287928 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287929 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005504477 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005504478 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC118841 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474039 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225476 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228107 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230457 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000036799   ⟹   ENSRNOP00000032995
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl573,135,361 - 73,188,893 (+)Ensembl
mRatBN7.2 Ensembl568,340,028 - 68,396,409 (+)Ensembl
Rnor_6.0 Ensembl570,528,688 - 70,578,273 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000127827   ⟹   ENSRNOP00000108834
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl573,135,558 - 73,189,181 (+)Ensembl
RefSeq Acc Id: NM_001108667   ⟹   NP_001102137
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8573,135,162 - 73,189,181 (+)NCBI
mRatBN7.2568,339,803 - 68,393,823 (+)NCBI
Rnor_6.0570,522,001 - 70,575,679 (+)NCBI
Rnor_5.0574,697,518 - 74,754,106 (+)NCBI
RGSC_v3.4571,155,051 - 71,208,525 (+)RGD
Celera567,234,078 - 67,287,987 (+)RGD
Sequence:
RefSeq Acc Id: XM_006238166   ⟹   XP_006238228
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8573,134,746 - 73,191,772 (+)NCBI
mRatBN7.2568,339,899 - 68,396,412 (+)NCBI
Rnor_6.0570,522,177 - 70,578,270 (+)NCBI
Rnor_5.0574,697,518 - 74,754,106 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006238169   ⟹   XP_006238231
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8573,135,371 - 73,191,772 (+)NCBI
mRatBN7.2568,340,041 - 68,396,412 (+)NCBI
Rnor_6.0570,522,239 - 70,578,270 (+)NCBI
Rnor_5.0574,697,518 - 74,754,106 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008763712   ⟹   XP_008761934
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8573,135,366 - 73,191,772 (+)NCBI
mRatBN7.2568,340,041 - 68,396,412 (+)NCBI
Rnor_6.0570,522,239 - 70,578,270 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039110244   ⟹   XP_038966172
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8573,135,386 - 73,191,772 (+)NCBI
mRatBN7.2568,340,041 - 68,396,412 (+)NCBI
RefSeq Acc Id: XM_039110247   ⟹   XP_038966175
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8573,135,373 - 73,191,772 (+)NCBI
mRatBN7.2568,340,041 - 68,392,141 (+)NCBI
RefSeq Acc Id: XM_039110248   ⟹   XP_038966176
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8573,135,365 - 73,191,772 (+)NCBI
mRatBN7.2568,340,041 - 68,392,110 (+)NCBI
RefSeq Acc Id: XM_039110249   ⟹   XP_038966177
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8573,135,373 - 73,191,772 (+)NCBI
mRatBN7.2568,340,041 - 68,392,141 (+)NCBI
RefSeq Acc Id: XM_063287921   ⟹   XP_063143991
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8573,134,746 - 73,191,772 (+)NCBI
RefSeq Acc Id: XM_063287923   ⟹   XP_063143993
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8573,135,400 - 73,191,772 (+)NCBI
RefSeq Acc Id: XM_063287924   ⟹   XP_063143994
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8573,140,508 - 73,191,772 (+)NCBI
RefSeq Acc Id: XM_063287925   ⟹   XP_063143995
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8573,134,746 - 73,191,772 (+)NCBI
RefSeq Acc Id: XM_063287926   ⟹   XP_063143996
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8573,134,746 - 73,191,772 (+)NCBI
RefSeq Acc Id: XM_063287927   ⟹   XP_063143997
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8573,134,746 - 73,191,772 (+)NCBI
RefSeq Acc Id: XM_063287928   ⟹   XP_063143998
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8573,135,382 - 73,191,772 (+)NCBI
RefSeq Acc Id: XM_063287929   ⟹   XP_063143999
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8573,134,746 - 73,191,772 (+)NCBI
RefSeq Acc Id: XR_005504477
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8573,135,400 - 73,169,531 (+)NCBI
mRatBN7.2568,340,041 - 68,374,268 (+)NCBI
RefSeq Acc Id: XR_005504478
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8573,135,400 - 73,187,420 (+)NCBI
mRatBN7.2568,340,041 - 68,392,056 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001102137 (Get FASTA)   NCBI Sequence Viewer  
  NP_001423932 (Get FASTA)   NCBI Sequence Viewer  
  NP_001423934 (Get FASTA)   NCBI Sequence Viewer  
  NP_001423935 (Get FASTA)   NCBI Sequence Viewer  
  NP_001423936 (Get FASTA)   NCBI Sequence Viewer  
  NP_001423937 (Get FASTA)   NCBI Sequence Viewer  
  NP_001423939 (Get FASTA)   NCBI Sequence Viewer  
  NP_001423940 (Get FASTA)   NCBI Sequence Viewer  
  NP_001423941 (Get FASTA)   NCBI Sequence Viewer  
  NP_001423942 (Get FASTA)   NCBI Sequence Viewer  
  NP_001423943 (Get FASTA)   NCBI Sequence Viewer  
  XP_006238228 (Get FASTA)   NCBI Sequence Viewer  
  XP_006238231 (Get FASTA)   NCBI Sequence Viewer  
  XP_008761934 (Get FASTA)   NCBI Sequence Viewer  
  XP_038966172 (Get FASTA)   NCBI Sequence Viewer  
  XP_038966175 (Get FASTA)   NCBI Sequence Viewer  
  XP_038966176 (Get FASTA)   NCBI Sequence Viewer  
  XP_038966177 (Get FASTA)   NCBI Sequence Viewer  
  XP_063143991 (Get FASTA)   NCBI Sequence Viewer  
  XP_063143993 (Get FASTA)   NCBI Sequence Viewer  
  XP_063143994 (Get FASTA)   NCBI Sequence Viewer  
  XP_063143995 (Get FASTA)   NCBI Sequence Viewer  
  XP_063143996 (Get FASTA)   NCBI Sequence Viewer  
  XP_063143997 (Get FASTA)   NCBI Sequence Viewer  
  XP_063143998 (Get FASTA)   NCBI Sequence Viewer  
  XP_063143999 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL91708 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000032995
  ENSRNOP00000032995.4
  ENSRNOP00000108834
  ENSRNOP00000108834.1
RefSeq Acc Id: NP_001102137   ⟸   NM_001108667
- UniProtKB: D3ZI33 (UniProtKB/TrEMBL),   A6KDP7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006238228   ⟸   XM_006238166
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006238231   ⟸   XM_006238169
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_008761934   ⟸   XM_008763712
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000032995   ⟸   ENSRNOT00000036799
RefSeq Acc Id: XP_038966172   ⟸   XM_039110244
- Peptide Label: isoform X1
- UniProtKB: D3ZI33 (UniProtKB/TrEMBL),   A6KDP7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038966175   ⟸   XM_039110247
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038966177   ⟸   XM_039110249
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038966176   ⟸   XM_039110248
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063143995   ⟸   XM_063287925
- Peptide Label: isoform X1
- UniProtKB: A6KDP7 (UniProtKB/TrEMBL),   D3ZI33 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063143991   ⟸   XM_063287921
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063143996   ⟸   XM_063287926
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063143997   ⟸   XM_063287927
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063143999   ⟸   XM_063287929
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063143998   ⟸   XM_063287928
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063143993   ⟸   XM_063287923
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063143994   ⟸   XM_063287924
- Peptide Label: isoform X1
- UniProtKB: A6KDP7 (UniProtKB/TrEMBL),   D3ZI33 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000108834   ⟸   ENSRNOT00000127827
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZI33-F1-model_v2 AlphaFold D3ZI33 1-461 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310087 AgrOrtholog
BioCyc Gene G2FUF-41265 BioCyc
Ensembl Genes ENSRNOG00000028129 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000036799 ENTREZGENE
  ENSRNOT00000036799.7 UniProtKB/TrEMBL
  ENSRNOT00000127827 ENTREZGENE
  ENSRNOT00000127827.1 UniProtKB/TrEMBL
InterPro FKTN_N UniProtKB/TrEMBL
  Fukutin-related UniProtKB/TrEMBL
  LicD UniProtKB/TrEMBL
KEGG Report rno:362520 UniProtKB/TrEMBL
NCBI Gene 362520 ENTREZGENE
PANTHER FUKUTIN UniProtKB/TrEMBL
  Fukutin-related UniProtKB/TrEMBL
Pfam FKTN_N UniProtKB/TrEMBL
  LicD UniProtKB/TrEMBL
PhenoGen Fktn PhenoGen
PROSITE PROKAR_LIPOPROTEIN UniProtKB/TrEMBL
RatGTEx ENSRNOG00000028129 RatGTEx
UniProt A0ABK0LS56_RAT UniProtKB/TrEMBL
  A6KDP7 ENTREZGENE, UniProtKB/TrEMBL
  D3ZI33 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-25 Fktn  fukutin  Fcmd_predicted  Fukuyama type congenital muscular dystrophy homolog (human) (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Fcmd_predicted  Fukuyama type congenital muscular dystrophy homolog (human) (predicted)    Fukuyama type congenital muscular dystrophy (fukutin) (predicted)  Name updated 1299863 APPROVED
2005-01-12 Fcmd_predicted  Fukuyama type congenital muscular dystrophy (fukutin) (predicted)      Symbol and Name status set to approved 70820 APPROVED