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Gene: Ndfip1 (Nedd4 family interacting protein 1) Rattus norvegicus

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Symbol:

Ndfip1

Name:

Nedd4 family interacting protein 1

RGD ID:

1310053

Description:

Predicted to enable WW domain binding activity. Predicted to be involved in several processes, including intracellular iron ion homeostasis; regulation of macromolecule metabolic process; and ubiquitin-dependent protein catabolic process. Predicted to act upstream of or within several processes, including negative regulation of interleukin-4 production; negative regulation of type 2 immune response; and regulation of lymphocyte activation. Predicted to be located in cell cortex. Predicted to be active in Golgi apparatus; endoplasmic reticulum; and perinuclear region of cytoplasm. Orthologous to human NDFIP1 (Nedd4 family interacting protein 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; alpha-Zearalanol.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC291609; NEDD4 family-interacting protein 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	NDFIP1 (Nedd4 family interacting protein 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Ndfip1 (Nedd4 family interacting protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ndfip1 (Nedd4 family interacting protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	NDFIP1 (Nedd4 family interacting protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	NDFIP1 (Nedd4 family interacting protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ndfip1 (Nedd4 family interacting protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	NDFIP1 (Nedd4 family interacting protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	NDFIP1 (Nedd4 family interacting protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ndfip1 (Nedd4 family interacting protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Ndfip1 (Nedd4 family interacting protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	C3orf49 (chromosome 3 open reading frame 49)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	NDFIP1 (Nedd4 family interacting protein 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Ndfip1 (Nedd4 family interacting protein 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Ndfip1 (Nedd4 family interacting protein 1)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ndfip1l (Nedd4 family interacting protein 1, like)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ndfip1 (Nedd4 family interacting protein 1)	Alliance	DIOPT (Ensembl Compara\|OrthoInspector\|PANTHER\|PhylomeDB)
Saccharomyces cerevisiae (baker's yeast):	BSD2	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Drosophila melanogaster (fruit fly):	Ndfip	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Ndfip	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	ndfip1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	ndfip1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	18	30,516,931 - 30,567,199 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	18	30,516,981 - 30,568,471 (+)	Ensembl				GRCr8
mRatBN7.2	18	30,265,808 - 30,316,068 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	30,250,613 - 30,322,311 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	18	30,370,117 - 30,420,290 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	18	31,133,009 - 31,183,042 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	18	30,468,294 - 30,518,347 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	18	31,574,759 - 31,625,286 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	31,574,821 - 31,625,274 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	18	31,252,665 - 31,303,463 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	18	31,351,538 - 31,401,736 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	18	29,904,818 - 29,954,984 (+)	NCBI		Celera
RGSC_v3.1	18	31,378,183 - 31,428,381 (+)	NCBI
Cytogenetic Map	18	p11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Hereditary Neoplastic Syndromes (ISO)

stroke (IEP)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,1,1-trichloroethane (ISO)

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,6-dinitrotoluene (EXP)

3,3',4,4'-tetrachlorobiphenyl (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-sulfonyldiphenol (ISO)

acrylamide (ISO)

all-trans-retinoic acid (ISO)

alpha-Zearalanol (EXP)

Aroclor 1254 (ISO)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (EXP,ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

buspirone (EXP)

Butylbenzyl phthalate (ISO)

cadmium atom (EXP)

carbamazepine (ISO)

chlorpyrifos (ISO)

clobetasol (ISO)

clofibrate (ISO)

coumestrol (ISO)

crocidolite asbestos (ISO)

dexamethasone (ISO)

diethylstilbestrol (ISO)

dorsomorphin (ISO)

Enterolactone (ISO)

fulvestrant (ISO)

gentamycin (EXP)

glafenine (EXP)

indometacin (ISO)

levonorgestrel (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

methoxychlor (EXP)

methylmercury chloride (ISO)

N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal (ISO)

N-methyl-4-phenylpyridinium (ISO)

paracetamol (ISO)

perfluorooctanoic acid (EXP)

phenobarbital (ISO)

phenylmercury acetate (ISO)

SB 431542 (ISO)

serpentine asbestos (ISO)

sodium arsenite (ISO)

testosterone undecanoate (ISO)

tetrachloromethane (ISO)

titanium dioxide (ISO)

trichloroethene (EXP)

uranium atom (ISO)

urethane (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

intracellular iron ion homeostasis (IEA,ISO)

metal ion transport (IEA)

negative regulation of inflammatory response (ISO)

negative regulation of interleukin-4 production (ISO)

negative regulation of isotype switching to IgE isotypes (ISO)

negative regulation of T cell proliferation (ISO)

negative regulation of type 2 immune response (ISO)

positive regulation of canonical NF-kappaB signal transduction (ISO)

positive regulation of protein catabolic process (ISO)

positive regulation of protein ubiquitination (IBA,IEA,ISO,ISS)

proteasome-mediated ubiquitin-dependent protein catabolic process (IEA,ISO)

regulation of isotype switching to IgG isotypes (ISO)

regulation of lymphocyte differentiation (ISO)

regulation of myeloid leukocyte differentiation (ISO)

ubiquitin-dependent protein catabolic process (IBA)

vacuolar transport (IEA)

Cellular Component

cell cortex (IEA,ISO)

cytoplasm (IEA)

dendrite (IEA)

endomembrane system (IEA)

endoplasmic reticulum (IBA)

endosome membrane (IEA)

extracellular region (IEA)

Golgi apparatus (IBA,IEA,ISO)

Golgi membrane (IEA)

neuron projection (IEA)

perinuclear region of cytoplasm (IBA,IEA,ISO)

synapse (IEA)

Molecular Function

protein binding (IPI,ISO)

WW domain binding (IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Differential regulation of Nedd4 ubiquitin ligases and their adaptor protein Ndfip1 in a rat model of ischemic stroke.	Lackovic J, etal., Exp Neurol. 2012 May;235(1):326-35. Epub 2012 Mar 5.
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	GOA pipeline	RGD automated data pipeline
5.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
7.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:11748237	PMID:12761501	PMID:15489334	PMID:17137798	PMID:18776082	PMID:22871113	PMID:25631046	PMID:37023120

Genomics

Comparative Map Data

Ndfip1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	18	30,516,931 - 30,567,199 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	18	30,516,981 - 30,568,471 (+)	Ensembl				GRCr8
mRatBN7.2	18	30,265,808 - 30,316,068 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	30,250,613 - 30,322,311 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	18	30,370,117 - 30,420,290 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	18	31,133,009 - 31,183,042 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	18	30,468,294 - 30,518,347 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	18	31,574,759 - 31,625,286 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	31,574,821 - 31,625,274 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	18	31,252,665 - 31,303,463 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	18	31,351,538 - 31,401,736 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	18	29,904,818 - 29,954,984 (+)	NCBI		Celera
RGSC_v3.1	18	31,378,183 - 31,428,381 (+)	NCBI
Cytogenetic Map	18	p11	NCBI

NDFIP1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	142,108,779 - 142,154,440 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	142,108,762 - 142,154,440 (+)	Ensembl			hg38	GRCh38
GRCh37	5	141,488,344 - 141,534,005 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	141,468,508 - 141,513,128 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	5	141,468,507 - 141,513,128	NCBI
Celera	5	137,569,742 - 137,615,392 (+)	NCBI		Celera
Cytogenetic Map	5	q31.3	NCBI
HuRef	5	136,635,249 - 136,680,894 (+)	NCBI		HuRef
CHM1_1	5	140,922,028 - 140,967,670 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	5	142,639,297 - 142,684,953 (+)	NCBI		T2T-CHM13v2.0

Ndfip1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	18	38,551,960 - 38,598,250 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	18	38,543,449 - 38,598,356 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	18	38,418,907 - 38,465,197 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	18	38,410,396 - 38,465,303 (+)	Ensembl			mm10	GRCm38
MGSCv37	18	38,578,629 - 38,624,060 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	18	38,536,434 - 38,586,631 (+)	NCBI		MGSCv36	mm8
Celera	18	39,761,460 - 39,806,803 (+)	NCBI		Celera
Cytogenetic Map	18	B3	NCBI
cM Map	18	20.32	NCBI

Ndfip1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955415	11,643,846 - 11,666,131 (-)	Ensembl
ChiLan1.0	NW_004955415	11,643,846 - 11,666,131 (-)	NCBI	ChiLan1.0	ChiLan1.0

NDFIP1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	137,354,843 - 137,398,983 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	135,494,488 - 135,538,959 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	137,467,161 - 137,511,569 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	143,596,345 - 143,622,913 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	143,600,789 - 143,622,913 (+)	Ensembl			panPan2	panpan1.1

NDFIP1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	36,978,148 - 37,065,247 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	36,961,024 - 37,064,303 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	34,065,772 - 34,117,671 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	37,468,313 - 37,520,209 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	37,467,811 - 37,521,377 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	34,543,424 - 34,595,458 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	35,354,316 - 35,406,223 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	36,162,143 - 36,214,039 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Ndfip1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	150,479,497 - 150,529,371 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936504	12,053,470 - 12,103,638 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936504	12,053,470 - 12,103,346 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NDFIP1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	143,629,783 - 143,734,520 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	2	143,688,946 - 143,734,523 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	149,890,960 - 149,924,216 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NDFIP1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	23	44,737,432 - 44,783,409 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	23	44,737,422 - 44,775,657 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666034	33,067,657 - 33,113,926 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ndfip1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624774	1,303,773 - 1,353,253 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624774	1,245,587 - 1,353,253 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Ndfip1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	15	6,463,493 - 6,511,062 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Ndfip1
251 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	404
Count of miRNA genes:	228
Interacting mature miRNAs:	281
Transcripts:	ENSRNOT00000018499
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1331733	Bp233	Blood pressure QTL 233	3.97196		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	25071126	83910656	Rat
2301409	Cm70	Cardiac mass QTL 70		0.001	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	18	7065728	52065728	Rat
1358358	Sradr6	Stress Responsive Adrenal Weight QTL 6	2.49		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	18	22015562	61600538	Rat
1331735	Rf44	Renal function QTL 44	2.981		urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	18	15642280	31610627	Rat
61382	Bp46	Blood pressure QTL 46	18.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	12216684	31644508	Rat
2301413	Bp318	Blood pressure QTL 318		0.002	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	26822186	71822186	Rat
12904716	Am21	Aortic mass QTL 21		0.005	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	18	7065728	52065728	Rat
1331741	Bp232	Blood pressure QTL 232	3.59112		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	18	23494057	85487725	Rat
12904714	Cm131	Cardiac mass QTL 131		0.002	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	18	7065728	52065728	Rat
12904715	Cm132	Cardiac mass QTL 132		0.001	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	18	7065728	52065728	Rat
6903345	Bp349	Blood pressure QTL 349	3.9		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	3917226	48917226	Rat
12904668	Bw188	Body weight QTL 188		0.03	body mass (VT:0001259)	body weight (CMO:0000012)	18	26822186	71822186	Rat
2313082	Bss85	Bone structure and strength QTL 85	0.8	0.0001	long bone metaphysis morphology trait (VT:0000133)	tibia midshaft total cross-sectional area (CMO:0001715)	18	15226101	42690662	Rat
12904669	Cm125	Cardiac mass QTL 125		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	18	26822186	71822186	Rat
6903347	Bp350	Blood pressure QTL 350	4.4		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	1	31610627	Rat
12904670	Cm126	Cardiac mass QTL 126		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	18	26822186	71822186	Rat
2312568	Glom21	Glomerulus QTL 21	2	0.005	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	18	5460455	42690191	Rat
6903349	Bp351	Blood pressure QTL 351	3.5		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	3917226	48917226	Rat
631509	Sald2	Serum aldosterone level QTL 2	2.9		blood aldosterone amount (VT:0005346)	serum aldosterone level (CMO:0000487)	18	26415821	71415821	Rat
6903351	Bp352	Blood pressure QTL 352	3.3		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	3917226	48917226	Rat
12904677	Kidm72	Kidney mass QTL 72		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	18	26822186	71822186	Rat
1331766	Bp236	Blood pressure QTL 236	3.022		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	1	31610627	Rat
12904673	Cm127	Cardiac mass QTL 127		0.005	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	18	26822186	71822186	Rat
12904675	Am19	Aortic mass QTL 19		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	18	26822186	71822186	Rat
631264	Scl22	Serum cholesterol level QTL 22	6.2		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	18	12216684	31644508	Rat
1331775	Bp235	Blood pressure QTL 235	3.201		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	15642280	31610627	Rat
2325839	Bp348	Blood pressure QTL 348		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	1	44930869	Rat
1600373	Mamtr6	Mammary tumor resistance QTL 6			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	18	19553532	85493247	Rat
2293708	Bss46	Bone structure and strength QTL 46	8.8	0.0001	lumbar vertebra morphology trait (VT:0010494)	lumbar vertebra cortical cross-sectional area (CMO:0001690)	18	12066482	57066482	Rat
1578667	Bss21	Bone structure and strength QTL 21	3.5		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	18	12066482	85493247	Rat
2312598	Bp340	Blood pressure QTL 340		0.05	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	3811902	30809809	Rat
2300180	Bmd67	Bone mineral density QTL 67	4.8	0.0001	femur mineral mass (VT:0010011)	bone mineral density (CMO:0001226)	18	1	34566578	Rat
2299160	Iddm35	Insulin dependent diabetes mellitus QTL 35	2.79		blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	18	4482648	49482648	Rat
1331753	Bp231	Blood pressure QTL 231	3.643		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	1	54490981	Rat
1578661	Bss20	Bone structure and strength QTL 20	3.7		femur morphology trait (VT:0000559)	femoral neck cross-sectional area (CMO:0001697)	18	12066482	85493247	Rat
11565454	Kidm59	Kidney mass QTL 59		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	18	7065728	52065728	Rat
1331754	Bp230	Blood pressure QTL 230	4.61609		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	15642280	86134022	Rat
2293661	Bss50	Bone structure and strength QTL 50	4.64	0.0003	lumbar vertebra size trait (VT:0010518)	lumbar vertebra trabecular cross-sectional area (CMO:0001692)	18	1	34566578	Rat
61375	Bp41	Blood pressure QTL 41	2.4		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	18	4307354	49307354	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
20	13	79	210	91	90	59	148	59	6	462	268	20	190	107	114	31	34	34

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001013059	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006254633	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC085887	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473974	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ214895	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ229568	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000018	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000018499 ⟹ ENSRNOP00000018499

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	18	30,265,869 - 30,322,311 (+)	Ensembl
Rnor_6.0 Ensembl	18	31,574,821 - 31,625,274 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000096236 ⟹ ENSRNOP00000078162

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	18	30,542,614 - 30,568,471 (+)	Ensembl
mRatBN7.2 Ensembl	18	30,291,465 - 30,322,307 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000097966 ⟹ ENSRNOP00000087620

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	18	30,290,743 - 30,322,307 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000104237 ⟹ ENSRNOP00000093040

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	18	30,516,981 - 30,568,471 (+)	Ensembl
mRatBN7.2 Ensembl	18	30,250,613 - 30,322,307 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000107021 ⟹ ENSRNOP00000095556

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	18	30,517,013 - 30,567,209 (+)	Ensembl
mRatBN7.2 Ensembl	18	30,265,864 - 30,316,027 (+)	Ensembl

RefSeq Acc Id:

NM_001013059 ⟹ NP_001013077

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	30,517,025 - 30,567,199 (+)	NCBI
mRatBN7.2	18	30,265,873 - 30,316,057 (+)	NCBI
Rnor_6.0	18	31,574,821 - 31,625,275 (+)	NCBI
Rnor_5.0	18	31,252,665 - 31,303,463 (+)	NCBI
RGSC_v3.4	18	31,351,538 - 31,401,736 (+)	RGD
Celera	18	29,904,818 - 29,954,984 (+)	RGD

Sequence:

show sequence

GAGCGTCCCTGCGTCGGCAGCGGCCATCCACACGCCGCGGCGCGTACCTCTCGGCCTCCCGGCG
ACCCCCAGCCGCGGCACCCGCGCTCGTTCAGCTCTCTCGCTCGCCCTCCTTCCCTGAGGCCTGC
TGCGCCATGGCTTTGGCGTTGGCGGCGCTGGCGGCGGTGGAGCCGGCCTGCGGCACTGGGTACC
AGCAGTTGCAGAATGAAGAGGAGCCTGGGGAGCGGGAACAGACTGCGGGTGACGCCCCTCCACC
CTACAGCAGCATCTCTGCGGAGAGTGCAGCATATTTTGACTACAAAGATGAATCTGGGTTTCCA
AAGCCCCCATCTTATAATGTGGCTACAACACTGCCCAGCTATGACGAGGCTGAGAGAACCAAGG
CTGAAGCCACCATCCCTTTGGTTCCTGGAAGAGATGAAGATTTTGTGGGTCGGGATGATTTTGA
TGATGCTGACCAGCTGAGGATAGGAAACGATGGGATTTTTATGTTAACCTTTTTCATGGCATTC
CTCTTCAACTGGATTGGGTTTTTCTTGTCTTTTTGCCTGACCACCTCAGCTGCGGGAAGGTATG
GGGCCATCTCAGGATTTGGTCTTTCTCTAATTAAGTGGATCCTTATTGTCAGGTTTTCCACCTA
TTTCCCTGGATACTTTGATGGCCAGTACTGGCTCTGGTGGGTGTTCTTGGTTTTAGGCTTTCTC
CTGTTTCTCAGAGGATTTATCAATTATGCAAAAGTTCGGAAGATGCCAGAAACTTTCTCAAATC
TCCCCAGGACCAGAGTTCTCTTTATTTATTAAAGATGTCTTCTGGCAAAGCTTCCTGCACTGAT
GAAGTCCCTCGAGAAGCGAGAGCACCTGCAGGAAGTGAATCACCACCAGGATGGAGGAACAGTC
ACCTGCTTTAAAAAATAAAGTACTGTTGAAAAAGATCATTTCTCTCTATTTGTTCCTAGGTGTA
AAATGTTAATAGTTAATGCAGAATTCTGTAATCATCGAATCATTAGTGGTTAATGTTTGTAAAA
GCTCTTGCAATCAAGTCTGTGATGTATTATTAATAATGCCTTATATATTGTTTGTAGTCATTTT
AAATAGCATGAGCCATGTCCCTATAGTCAGTAGGGGGCAATCTTGCTTTATTCATCCTCCATCT
CAAAGCAGATTTGAAATTACAGATTAGTGTAAGCTATGGATAAGGCTGGCTGTTTGAAAAGGGG
TTTTCTCAAAAGTCAAAACTTTGGTTATGACTGCATTTCTGCACATAATCCATATTTCCTGTTC
AAATTAATCTAGAAATGCGTTTAATTGTACTGTGTGTGAACATCTGGAAGCAAAACCATAGTGC
AAAGTTCACTGTAATGTTAACAAAAAATGTCCTCAATTGGTAAATAAGCATTACTTTTTCATAG
TCTATATTCAGAAATTACCTTTTCATTCCGTAGTTCTGTGTAGTTCATATAAAATGGAAAGGGC
AAAGATAGATTCAGATTAAATATTAAATATTCTTCTGCAAACTGGATAGAATCTCAGAGGGTCA
GGAGCAAAGAGTTAGTTTGGAACTTTTGAGAGGATCCCTAACATTCTGTACTCCTTGCTTTTAC
AACTGTTGTAACTGTAGAATGATGTGCTTGCTGCCCAAGTGCTAGTTCACTTTGGTTGGTATAT
TAAACTGTAAATACAATAGAACATTAATAAATGTCTCTTGTGTAGCAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006254633 ⟹ XP_006254695

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	30,516,931 - 30,567,199 (+)	NCBI
mRatBN7.2	18	30,265,808 - 30,316,068 (+)	NCBI
Rnor_6.0	18	31,574,759 - 31,625,286 (+)	NCBI
Rnor_5.0	18	31,252,665 - 31,303,463 (+)	NCBI

Sequence:

show sequence

GTCCCCGCCTCCTACCCAGGGGCCGCGGCGGAGCCTTGGCGGCGGCGCTCAGTGCCTGCGGAGA
GCGTCCCTGCGTCGGCAGCGGCCATCCACACGCCGCGGCGCGTACCTCTCGGCCTCCCGGCGAC
CCCCAGCCGCGGCACCCGCGCTCGTTCAGCTCTCTCGCTCGCCCTCCTTCCCTGAGGCCTGCTG
CGCCATGGCTTTGGCGTTGGCGGCGCTGGCGGCGGTGGAGCCGGCCTGCGGCACTGGGTACCAG
CAGTTGCAGAATGAAGAGGAGCCTGGGGAGCGGGAACAGACTGCGGGTGACGCCCCTCCACCCT
ACAGCAGCATCTCTGCGGAGAGTGCAGCATATTTTGACTACAAAGATGAATCTGGGTTTCCAAA
GCCCCCATCTTATAATGTGGCTACAACACTGCCCAGCTATGACGAGGCTGAGAGAACCAAGGCT
GAAGCCACCATCCCTTTGGTTCCTGGAAGAGATGAAGATTTTGTGGGTCGGGATGATTTTGATG
ATGCTGACCAGCTGAGGATAGGAAACGATGGGATTTTTATGTTAACCTTTTTCATGGCATTCCT
CTTCAACTGGATTGGGTTTTTCTTGTCTTTTTGCCTGACCACCTCAGCTGCGGGAAGGTATGGG
GCCATCTCAGGATTTGGTCTTTCTCTAATTAAGTGGATCCTTATTGTCAGGTTTTCCACCTATT
TCCCTGGATACTTTGATGGCCAGTACTGGCTCTGGTGGGTGTTCTTGGTTTTAGGCTTTCTCCT
GTTTCTCAGAGGATTTATCAATTATGCAAAAGTTCGGAAGATGCCAGAAACTTTCTCAAATCTC
CCCAGGACCAGAGTTCTCTTTATTTATTAAAGGCTGCCTAGAGCTTGACTGTTCAGTGTCCTTC
TCTGGCAGATGTCTTCTGGCAAAGCTTCCTGCACTGATGAAGTCCCTCGAGAAGCGAGAGCACC
TGCAGGAAGTGAATCACCACCAGGATGGAGGAACAGTCACCTGCTTTAAAAAATAAAGTACTGT
TGAAAAAGATCATTTCTCTCTATTTGTTCCTAGGTGTAAAATGTTAATAGTTAATGCAGAATTC
TGTAATCATCGAATCATTAGTGGTTAATGTTTGTAAAAGCTCTTGCAATCAAGTCTGTGATGTA
TTATTAATAATGCCTTATATATTGTTTGTAGTCATTTTAAATAGCATGAGCCATGTCCCTATAG
TCAGTAGGGGGCAATCTTGCTTTATTCATCCTCCATCTCAAAGCAGATTTGAAATTACAGATTA
GTGTAAGCTATGGATAAGGCTGGCTGTTTGAAAAGGGGTTTTCTCAAAAGTCAAAACTTTGGTT
ATGACTGCATTTCTGCACATAATCCATATTTCCTGTTCAAATTAATCTAGAAATGCGTTTAATT
GTACTGTGTGTGAACATCTGGAAGCAAAACCATAGTGCAAAGTTCACTGTAATGTTAACAAAAA
ATGTCCTCAATTGGTAAATAAGCATTACTTTTTCATAGTCTATATTCAGAAATTACCTTTTCAT
TCCGTAGTTCTGTGTAGTTCATATAAAATGGAAAGGGCAAAGATAGATTCAGATTAAATATTAA
ATATTCTTCTGCAAACTGGATAGAATCTCAGAGGGTCAGGAGCAAAGAGTTAGTTTGGAACTTT
TGAGAGGATCCCTAACATTCTGTACTCCTTGCTTTTACAACTGTTGTAACTGTAGAATGATGTG
CTTGCTGCCCAAGTGCTAGTTCACTTTGGTTGGTATATTAAACTGTAAATACAATAGAACATTA
ATAAATGTCTCTTGTGTAGCACCTTTCCTGTA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001013077	(Get FASTA)	NCBI Sequence Viewer
	XP_006254695	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH85887	(Get FASTA)	NCBI Sequence Viewer
	EDL76450	(Get FASTA)	NCBI Sequence Viewer
	EDL76451	(Get FASTA)	NCBI Sequence Viewer
	EDL76452	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000018499.4
	ENSRNOP00000093040
GenBank Protein	Q5U2S1	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001013077 ⟸ NM_001013059

- UniProtKB:

Q5U2S1 (UniProtKB/Swiss-Prot), A6J3G8 (UniProtKB/TrEMBL), A0A8I5ZKG6 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MALALAALAAVEPACGTGYQQLQNEEEPGEREQTAGDAPPPYSSISAESAAYFDYKDESGFPKP
PSYNVATTLPSYDEAERTKAEATIPLVPGRDEDFVGRDDFDDADQLRIGNDGIFMLTFFMAFLF
NWIGFFLSFCLTTSAAGRYGAISGFGLSLIKWILIVRFSTYFPGYFDGQYWLWWVFLVLGFLLF
LRGFINYAKVRKMPETFSNLPRTRVLFIY

hide sequence

RefSeq Acc Id:	XP_006254695 ⟸ XM_006254633
- Peptide Label:	isoform X1
- UniProtKB:	Q5U2S1 (UniProtKB/Swiss-Prot), A6J3G8 (UniProtKB/TrEMBL), A0A8I5ZKG6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MALALAALAAVEPACGTGYQQLQNEEEPGEREQTAGDAPPPYSSISAESAAYFDYKDESGFPKP PSYNVATTLPSYDEAERTKAEATIPLVPGRDEDFVGRDDFDDADQLRIGNDGIFMLTFFMAFLF NWIGFFLSFCLTTSAAGRYGAISGFGLSLIKWILIVRFSTYFPGYFDGQYWLWWVFLVLGFLLF LRGFINYAKVRKMPETFSNLPRTRVLFIY hide sequence

Ensembl Acc Id:

ENSRNOP00000018499 ⟸ ENSRNOT00000018499

Ensembl Acc Id:

ENSRNOP00000087620 ⟸ ENSRNOT00000097966

Ensembl Acc Id:

ENSRNOP00000093040 ⟸ ENSRNOT00000104237

Ensembl Acc Id:

ENSRNOP00000078162 ⟸ ENSRNOT00000096236

Ensembl Acc Id:

ENSRNOP00000095556 ⟸ ENSRNOT00000107021

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5U2S1-F1-model_v2	AlphaFold	Q5U2S1	1-221	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13700740

Promoter ID:

EPDNEW_R11264

Type:

initiation region

Name:

Ndfip1_1

Description:

Nedd4 family interacting protein 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	18	31,574,809 - 31,574,869	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1310053	AgrOrtholog
BioCyc Gene	G2FUF-7771	BioCyc
Ensembl Genes	ENSRNOG00000013562	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000018499.6	UniProtKB/Swiss-Prot
	ENSRNOT00000104237	ENTREZGENE
IMAGE_CLONE	IMAGE:7192378	IMAGE-MGC_LOAD
InterPro	NEDD4/Bsd2	UniProtKB/Swiss-Prot
KEGG Report	rno:291609	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:94675	IMAGE-MGC_LOAD
NCBI Gene	291609	ENTREZGENE
PANTHER	NEDD4 FAMILY-INTERACTING PROTEIN 1	UniProtKB/Swiss-Prot
	PTHR13396	UniProtKB/Swiss-Prot
Pfam	DUF2370	UniProtKB/Swiss-Prot
PhenoGen	Ndfip1	PhenoGen
RatGTEx	ENSRNOG00000013562	RatGTEx
UniProt	A0A8I5ZKG6	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6AJ70_RAT	UniProtKB/TrEMBL
	A0A8I6ANN8_RAT	UniProtKB/TrEMBL
	A6J3G8	ENTREZGENE, UniProtKB/TrEMBL
	A6J3H0_RAT	UniProtKB/TrEMBL
	NFIP1_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2005-12-06	Ndfip1	Nedd4 family interacting protein 1	Ndfip1_predicted	Nedd4 family interacting protein 1 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Ndfip1_predicted	Nedd4 family interacting protein 1 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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