Dbndd1 (dysbindin domain containing 1) - Rat Genome Database

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Gene: Dbndd1 (dysbindin domain containing 1) Rattus norvegicus
Analyze
Symbol: Dbndd1
Name: dysbindin domain containing 1
RGD ID: 1310008
Description: Predicted to be involved in regulation of signal transduction. Predicted to be located in cytoplasm. Orthologous to human DBNDD1 (dysbindin domain containing 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; gentamycin.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: dysbindin (dystrobrevin binding protein 1) domain containing 1; dysbindin domain-containing protein 1; LOC361437; RGD1310008; similar to RIKEN cDNA 2810427I04, DNA segment, Chr 8, ERATO Doi 590, expressed
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81968,447,641 - 68,461,272 (-)NCBIGRCr8
mRatBN7.21951,539,154 - 51,548,441 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1951,539,148 - 51,548,444 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1958,337,394 - 58,346,710 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01959,011,311 - 59,020,607 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01961,236,005 - 61,245,314 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01956,302,704 - 56,311,991 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1956,302,705 - 56,311,991 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01967,012,417 - 67,021,168 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41953,825,048 - 53,834,055 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11953,829,929 - 53,838,936 (-)NCBI
Celera1950,770,518 - 50,779,793 (-)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:19573021   PMID:20531346   PMID:21502952   PMID:21998198   PMID:22337344   PMID:23954924   PMID:24385487  


Genomics

Comparative Map Data
Dbndd1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81968,447,641 - 68,461,272 (-)NCBIGRCr8
mRatBN7.21951,539,154 - 51,548,441 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1951,539,148 - 51,548,444 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1958,337,394 - 58,346,710 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01959,011,311 - 59,020,607 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01961,236,005 - 61,245,314 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01956,302,704 - 56,311,991 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1956,302,705 - 56,311,991 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01967,012,417 - 67,021,168 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41953,825,048 - 53,834,055 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11953,829,929 - 53,838,936 (-)NCBI
Celera1950,770,518 - 50,779,793 (-)NCBICelera
Cytogenetic Map19q12NCBI
DBNDD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381690,004,871 - 90,019,890 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1690,004,871 - 90,019,890 (-)EnsemblGRCh38hg38GRCh38
GRCh371690,071,279 - 90,086,298 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361688,598,780 - 88,613,438 (-)NCBINCBI36Build 36hg18NCBI36
Celera1675,136,096 - 75,150,124 (-)NCBICelera
Cytogenetic Map16q24.3NCBI
HuRef1675,763,537 - 75,777,892 (-)NCBIHuRef
CHM1_11691,483,065 - 91,497,720 (-)NCBICHM1_1
T2T-CHM13v2.01696,090,776 - 96,106,065 (-)NCBIT2T-CHM13v2.0
Dbndd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398124,231,744 - 124,245,535 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8124,231,457 - 124,242,202 (-)EnsemblGRCm39 Ensembl
GRCm388123,504,718 - 123,518,277 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8123,504,718 - 123,515,463 (-)EnsemblGRCm38mm10GRCm38
MGSCv378126,028,618 - 126,039,355 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368126,391,778 - 126,401,442 (-)NCBIMGSCv36mm8
Celera8127,744,865 - 127,755,598 (-)NCBICelera
Cytogenetic Map8E1NCBI
cM Map872.1NCBI
Dbndd1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555413,463,773 - 3,470,293 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555413,462,667 - 3,465,769 (-)NCBIChiLan1.0ChiLan1.0
DBNDD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21899,851,990 - 99,866,367 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan116105,739,689 - 105,754,041 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01670,762,881 - 70,777,339 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11690,426,028 - 90,430,480 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1690,426,028 - 90,441,525 (-)Ensemblpanpan1.1panPan2
DBNDD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1563,608,941 - 63,621,927 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl563,619,160 - 63,620,670 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha563,626,664 - 63,638,278 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0563,841,594 - 63,853,221 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl563,841,630 - 63,850,101 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1563,861,944 - 63,873,556 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0563,699,658 - 63,711,276 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0564,105,815 - 64,117,437 (+)NCBIUU_Cfam_GSD_1.0
Dbndd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934924,368,062 - 24,371,629 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936641120,849 - 124,124 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936641121,313 - 125,189 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DBNDD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6111,212 - 119,102 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16111,053 - 119,112 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26215,306 - 223,327 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DBNDD1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1575,327,897 - 75,341,271 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604774,103 - 88,268 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dbndd1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474649,455 - 57,585 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474649,537 - 58,709 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Dbndd1
72 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:148
Count of miRNA genes:107
Interacting mature miRNAs:116
Transcripts:ENSRNOT00000014090
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2313395Anxrr26Anxiety related response QTL 26aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)194997648153225766Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)191563020157337602Rat
61350Bp32Blood pressure QTL 320.012arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)192048357557337602Rat
5135224Leukc1Leukocyte quantity QTL 1eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)194434021455283277Rat
724546Kidm3Kidney mass QTL 33.1kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)192932249057337602Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)191545586057337602Rat
1358200Insglur2Insulin/glucose ratio QTL 24.1blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)193383821455283146Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19218792756457239Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19409615555283277Rat
2298478Eau8Experimental allergic uveoretinitis QTL 80.0163uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)191715443357337602Rat

Markers in Region
RH132136  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21951,539,194 - 51,539,379 (+)MAPPERmRatBN7.2
Rnor_6.01956,302,745 - 56,302,929NCBIRnor6.0
Rnor_5.01967,012,458 - 67,012,642UniSTSRnor5.0
RGSC_v3.41953,825,089 - 53,825,273UniSTSRGSC3.4
Celera1950,770,559 - 50,770,743UniSTS
RH 3.4 Map19753.99UniSTS
Cytogenetic Map19q12UniSTS
RH133199  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21951,538,921 - 51,539,129 (+)MAPPERmRatBN7.2
Rnor_6.01956,302,472 - 56,302,679NCBIRnor6.0
Rnor_5.01967,012,185 - 67,012,392UniSTSRnor5.0
RGSC_v3.41953,824,816 - 53,825,023UniSTSRGSC3.4
Celera1950,770,286 - 50,770,493UniSTS
RH 3.4 Map19712.01UniSTS
Cytogenetic Map19q12UniSTS
BF399501  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21951,539,920 - 51,540,147 (+)MAPPERmRatBN7.2
Rnor_6.01956,303,471 - 56,303,697NCBIRnor6.0
Rnor_5.01967,013,184 - 67,013,410UniSTSRnor5.0
RGSC_v3.41953,825,815 - 53,826,041UniSTSRGSC3.4
Celera1950,771,285 - 50,771,511UniSTS
RH 3.4 Map19708.81UniSTS
Cytogenetic Map19q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 37 113 74 73 42 25 42 6 189 85 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000014090   ⟹   ENSRNOP00000014090
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1951,539,151 - 51,548,444 (-)Ensembl
Rnor_6.0 Ensembl1956,302,705 - 56,311,991 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000105889   ⟹   ENSRNOP00000096975
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1951,539,148 - 51,548,441 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000109686   ⟹   ENSRNOP00000086403
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1951,540,154 - 51,548,441 (-)Ensembl
RefSeq Acc Id: NM_001014156   ⟹   NP_001014178
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81968,447,641 - 68,456,928 (-)NCBI
mRatBN7.21951,539,154 - 51,548,441 (-)NCBI
Rnor_6.01956,302,704 - 56,311,991 (-)NCBI
Rnor_5.01967,012,417 - 67,021,168 (-)NCBI
RGSC_v3.41953,825,048 - 53,834,055 (-)RGD
Celera1950,770,518 - 50,779,793 (-)RGD
Sequence:
RefSeq Acc Id: XM_063278165   ⟹   XP_063134235
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81968,447,641 - 68,461,272 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001014178 (Get FASTA)   NCBI Sequence Viewer  
  XP_063134235 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH88277 (Get FASTA)   NCBI Sequence Viewer  
  EDL92815 (Get FASTA)   NCBI Sequence Viewer  
  EDL92816 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000014090.7
  ENSRNOP00000086403.1
  ENSRNOP00000096975.1
GenBank Protein Q5M831 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001014178   ⟸   NM_001014156
- UniProtKB: Q5M831 (UniProtKB/Swiss-Prot),   A0A0A0MXW5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000014090   ⟸   ENSRNOT00000014090
Ensembl Acc Id: ENSRNOP00000096975   ⟸   ENSRNOT00000105889
Ensembl Acc Id: ENSRNOP00000086403   ⟸   ENSRNOT00000109686
RefSeq Acc Id: XP_063134235   ⟸   XM_063278165
- Peptide Label: isoform X1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5M831-F1-model_v2 AlphaFold Q5M831 1-160 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310008 AgrOrtholog
BioCyc Gene G2FUF-5321 BioCyc
Ensembl Genes ENSRNOG00000026974 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000014090.6 UniProtKB/TrEMBL
  ENSRNOT00000105889.1 UniProtKB/TrEMBL
  ENSRNOT00000109686.1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7381798 IMAGE-MGC_LOAD
InterPro Dysbindin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:361437 UniProtKB/Swiss-Prot
MGC_CLONE MGC:109128 IMAGE-MGC_LOAD
NCBI Gene 361437 ENTREZGENE
PANTHER DYSBINDIN DOMAIN-CONTAINING PROTEIN 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR16294 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Dysbindin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Dbndd1 PhenoGen
RatGTEx ENSRNOG00000026974 RatGTEx
UniProt A0A0A0MXW5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AUA7_RAT UniProtKB/TrEMBL
  A0A8I6GEW7_RAT UniProtKB/TrEMBL
  DBND1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-06-22 Dbndd1  dysbindin domain containing 1  Dbndd1  dysbindin (dystrobrevin binding protein 1) domain containing 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-26 Dbndd1  dysbindin (dystrobrevin binding protein 1) domain containing 1  RGD1310008  similar to RIKEN cDNA 2810427I04; DNA segment, Chr 8, ERATO Doi 590, expressed  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 RGD1310008  similar to RIKEN cDNA 2810427I04; DNA segment, Chr 8, ERATO Doi 590, expressed  RGD1310008_predicted  similar to RIKEN cDNA 2810427I04; DNA segment, Chr 8, ERATO Doi 590, expressed (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1310008_predicted  similar to RIKEN cDNA 2810427I04; DNA segment, Chr 8, ERATO Doi 590, expressed (predicted)  LOC361437_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC361437_predicted  similar to RIKEN cDNA 2810427I04; DNA segment, Chr 8, ERATO Doi 590, expressed (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL