Sult5a1 (sulfotransferase family 5A, member 1) - Rat Genome Database

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Gene: Sult5a1 (sulfotransferase family 5A, member 1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Sult5a1
Name: sulfotransferase family 5A, member 1
RGD ID: 1310002
Description: Predicted to enable sulfotransferase activity. Predicted to be involved in sulfation. Predicted to be active in cytoplasm; INTERACTS WITH 17alpha-ethynylestradiol; 6-propyl-2-thiouracil; alendronic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC292077
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81968,097,808 - 68,115,426 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1968,097,808 - 68,112,656 (-)EnsemblGRCr8
mRatBN7.21951,189,287 - 51,204,275 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1951,189,287 - 51,204,362 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1957,984,460 - 57,999,178 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01958,664,210 - 58,679,058 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01960,883,060 - 60,897,774 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01955,952,861 - 55,978,583 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1955,952,853 - 55,967,836 (-)Ensemblrn6Rnor6.0
Rnor_5.01966,658,233 - 66,684,110 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41953,472,683 - 53,498,840 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1950,424,891 - 50,450,593 (-)NCBICelera
RGSC_v3.11953,477,564 - 53,497,225 (-)NCBI
Cytogenetic Map19q12NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
sulfation  (IBA)

Cellular Component
cytoplasm  (IBA,IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548  


Genomics

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:49
Count of miRNA genes:41
Interacting mature miRNAs:46
Transcripts:ENSRNOT00000051452
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631840Niddm38Non-insulin dependent diabetes mellitus QTL 383.86blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)191032907674246245Rat
724546Kidm3Kidney mass QTL 33.1kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)194622677874246245Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)193236531174246245Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)193628974246245Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)192409397369093973Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191083361874246245Rat
2303628Vencon9Ventilatory control QTL 90.005respiration trait (VT:0001943)minute ventilation (CMO:0000132)192318858668188586Rat
2313395Anxrr26Anxiety related response QTL 26aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)194438513474246245Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)193253961574246245Rat
5135224Leukc1Leukocyte quantity QTL 1eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)196124916174246245Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)193177788874246245Rat
1554318Bmd5Bone mineral density QTL 512.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)192318858668188586Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19219431774246245Rat
1549835Tcas7Tongue tumor susceptibility QTL 70.001tongue integrity trait (VT:0010553)squamous cell carcinoma of the head and neck tumor number (CMO:0001876)194172254674246245Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19219431774246245Rat

Markers in Region
RH129205  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21951,189,321 - 51,189,506 (+)MAPPERmRatBN7.2
Rnor_6.01955,952,895 - 55,953,079NCBIRnor6.0
Rnor_5.01966,658,267 - 66,658,451UniSTSRnor5.0
RGSC_v3.41953,472,717 - 53,472,901UniSTSRGSC3.4
Celera1950,424,925 - 50,425,109UniSTS
RH 3.4 Map19709.91UniSTS
Cytogenetic Map19q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
11 12 67 149 90 89 58 34 58 6 273 134 11 128 62 92 31 16 16

Sequence


Ensembl Acc Id: ENSRNOT00000051452   ⟹   ENSRNOP00000045466
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1968,097,808 - 68,112,656 (-)Ensembl
mRatBN7.2 Ensembl1951,189,287 - 51,204,362 (-)Ensembl
Rnor_6.0 Ensembl1955,952,853 - 55,967,836 (-)Ensembl
RefSeq Acc Id: NM_001201369   ⟹   NP_001188298
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81968,097,808 - 68,112,656 (-)NCBI
mRatBN7.21951,189,287 - 51,204,135 (-)NCBI
Rnor_6.01955,952,862 - 55,967,700 (-)NCBI
Rnor_5.01966,658,233 - 66,684,110 (-)NCBI
Celera1950,424,892 - 50,439,710 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039097651   ⟹   XP_038953579
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81968,098,547 - 68,112,791 (-)NCBI
mRatBN7.21951,190,026 - 51,204,263 (-)NCBI
RefSeq Acc Id: XM_039097652   ⟹   XP_038953580
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81968,098,547 - 68,115,426 (-)NCBI
mRatBN7.21951,190,026 - 51,204,275 (-)NCBI
RefSeq Acc Id: XM_063277951   ⟹   XP_063134021
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81968,097,808 - 68,112,773 (-)NCBI
RefSeq Acc Id: NP_001188298   ⟸   NM_001201369
- UniProtKB: D4ADX9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000045466   ⟸   ENSRNOT00000051452
RefSeq Acc Id: XP_038953580   ⟸   XM_039097652
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038953579   ⟸   XM_039097651
- Peptide Label: isoform X1
- UniProtKB: D4ADX9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063134021   ⟸   XM_063277951
- Peptide Label: isoform X3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4ADX9-F1-model_v2 AlphaFold D4ADX9 1-353 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701216
Promoter ID:EPDNEW_R11740
Type:single initiation site
Name:Sult5a1_1
Description:sulfotransferase family 5A, member 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01955,967,758 - 55,967,818EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310002 AgrOrtholog
BioCyc Gene G2FUF-5341 BioCyc
Ensembl Genes ENSRNOG00000015695 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000051452 ENTREZGENE
  ENSRNOT00000051452.7 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro P-loop_NTPase UniProtKB/TrEMBL
  Sulfotransferase_dom UniProtKB/TrEMBL
NCBI Gene 292077 ENTREZGENE
PANTHER SULFOTRANSFERASE SULT UniProtKB/TrEMBL
Pfam Sulfotransfer_1 UniProtKB/TrEMBL
PhenoGen Sult5a1 PhenoGen
RatGTEx ENSRNOG00000015695 RatGTEx
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt D4ADX9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Sult5a1  sulfotransferase family 5A, member 1   Sult5a1_predicted  sulfotransferase family 5A, member 1 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Sult5a1_predicted  sulfotransferase family 5A, member 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED