Mcee (methylmalonyl CoA epimerase) - Rat Genome Database

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Gene: Mcee (methylmalonyl CoA epimerase) Rattus norvegicus
Analyze
Symbol: Mcee
Name: methylmalonyl CoA epimerase
RGD ID: 1309966
Description: Predicted to enable methylmalonyl-CoA epimerase activity. Predicted to be involved in L-methylmalonyl-CoA metabolic process. Orthologous to human MCEE (methylmalonyl-CoA epimerase); PARTICIPATES IN 3-hydroxy-3-methylglutaryl-CoA lyase deficiency pathway; 3-hydroxyisobutyric aciduria pathway; 3-methylcrotonyl CoA carboxylase 1 deficiency pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC293829; methylmalonyl-CoA epimerase, mitochondrial
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81127,376,311 - 127,399,551 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1127,376,298 - 127,400,367 (+)EnsemblGRCr8
mRatBN7.21117,964,576 - 117,987,779 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1117,964,576 - 117,988,484 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1125,938,584 - 125,963,511 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01133,121,136 - 133,146,060 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01125,952,976 - 125,977,879 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01125,229,487 - 125,252,692 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1125,229,469 - 125,252,666 (+)Ensemblrn6Rnor6.0
Rnor_5.01126,338,537 - 126,361,726 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41118,832,889 - 118,856,087 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1110,219,737 - 110,242,933 (+)NCBICelera
RGSC_v3.11118,921,291 - 118,934,299 (+)NCBI
Cytogenetic Map1q22NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11481338   PMID:14651853   PMID:18614015   PMID:34800366  


Genomics

Comparative Map Data
Mcee
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81127,376,311 - 127,399,551 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1127,376,298 - 127,400,367 (+)EnsemblGRCr8
mRatBN7.21117,964,576 - 117,987,779 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1117,964,576 - 117,988,484 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1125,938,584 - 125,963,511 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01133,121,136 - 133,146,060 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01125,952,976 - 125,977,879 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01125,229,487 - 125,252,692 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1125,229,469 - 125,252,666 (+)Ensemblrn6Rnor6.0
Rnor_5.01126,338,537 - 126,361,726 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41118,832,889 - 118,856,087 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1110,219,737 - 110,242,933 (+)NCBICelera
RGSC_v3.11118,921,291 - 118,934,299 (+)NCBI
Cytogenetic Map1q22NCBI
MCEE
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38271,109,687 - 71,130,229 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl271,109,684 - 71,130,279 (-)Ensemblhg38GRCh38
GRCh37271,336,817 - 71,357,359 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36271,190,327 - 71,210,867 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34271,248,473 - 71,269,014NCBI
Celera271,187,499 - 71,208,089 (-)NCBICelera
Cytogenetic Map2p13.3NCBI
HuRef271,073,464 - 71,094,057 (-)NCBIHuRef
CHM1_1271,266,126 - 71,286,714 (-)NCBICHM1_1
T2T-CHM13v2.0271,120,700 - 71,141,269 (-)NCBIT2T-CHM13v2.0
Mcee
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39764,042,370 - 64,061,869 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl764,042,355 - 64,061,873 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38764,392,622 - 64,412,121 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl764,392,607 - 64,412,125 (+)Ensemblmm10GRCm38
MGSCv37771,537,657 - 71,557,005 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36764,271,721 - 64,291,069 (+)NCBIMGSCv36mm8
Celera761,841,038 - 61,861,764 (+)NCBICelera
Cytogenetic Map7CNCBI
cM Map734.65NCBI
Mcee
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541629,685,385 - 29,698,557 (-)Ensembl
ChiLan1.0NW_00495541629,684,557 - 29,703,495 (-)NCBIChiLan1.0ChiLan1.0
MCEE
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21255,256,982 - 55,277,547 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A55,259,725 - 55,282,160 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A71,154,176 - 71,176,679 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A72,656,860 - 72,677,401 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A72,656,860 - 72,677,401 (-)EnsemblpanPan2panpan1.1
MCEE
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1338,080,570 - 38,107,832 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl338,080,611 - 38,107,830 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha340,764,994 - 40,792,312 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0338,457,719 - 38,485,060 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl338,457,790 - 38,485,060 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1337,982,654 - 38,010,337 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0338,243,298 - 38,270,570 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0338,450,615 - 38,478,183 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Mcee
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640145,343,845 - 145,363,379 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936483970,452 - 990,638 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936483971,148 - 990,634 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MCEE
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1143,993,394 - 144,024,879 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11143,993,714 - 144,022,372 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21159,939,241 - 159,967,926 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MCEE
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11436,038,559 - 36,055,519 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1436,039,058 - 36,057,467 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604575,972,681 - 75,989,137 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mcee
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247681,972,545 - 1,989,269 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247681,973,167 - 1,989,269 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Mcee
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v12135,990,719 - 136,015,690 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Mcee
207 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:9
Count of miRNA genes:6
Interacting mature miRNAs:8
Transcripts:ENSRNOT00000021884
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631496Bp97Blood pressure QTL 973.08arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1115183611176289080Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)187889942132889942Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)151941022208479811Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)139728272132889942Rat
1331793Bp200Blood pressure QTL 2003.71601arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1102780511182384005Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)151940904168768703Rat
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1101228864146228864Rat
1354591Cm36Cardiac mass QTL 364.1heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1111949780210707719Rat
1331800Scl25Serum cholesterol level QTL 253.013blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)187785026142582336Rat
631684Bp117Blood pressure QTL 1178.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1120082258165082258Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183019780128019780Rat
9590300Scort16Serum corticosterone level QTL 164.390.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1112521556157521556Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134184556172281316Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)166009857160501508Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
631519Pia11Pristane induced arthritis QTL 115.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)193903998191260518Rat
1302788Scl19Serum cholesterol QTL 194.60.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)166400974132889942Rat
61399Tcat1Tongue tumor resistance QTL 13.3tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 5 mm (CMO:0001879)1108680016153680016Rat
631569Bp93Blood pressure QTL 930.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1115183611131244255Rat
2313083Bmd74Bone mineral density QTL 7440.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)191302413136302413Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)151511344153680016Rat
724567Tcas6Tongue tumor susceptibility QTL 66.85tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)1102359314153680016Rat
152025232Bw192Body weight QTL 1923.93body mass (VT:0001259)1127329268206393015Rat
724521Uae1Urinary albumin excretion QTL 13.80.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)199645382182701046Rat
1358902Bw47Body weight QTL 471.67body mass (VT:0001259)body weight (CMO:0000012)199645382221502378Rat
1354615Cm32Cardiac mass QTL 325.2heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1111949780210707719Rat
1358192Ept13Estrogen-induced pituitary tumorigenesis QTL 133.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)186622262131622262Rat
8655649Arrd1Age-related retinal degeneration QTL 14.89retinal layer morphology trait (VT:0003727)percentage of study population developing retinopathy during a period of time (CMO:0002453)1109493780193400781Rat
8694370Bw154Body weight QTL 1548.910.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)1112521556157521556Rat
2317833Alcrsp19Alcohol response QTL 1912.40.001response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1110389869155389869Rat
1300153Bp171Blood pressure QTL 1713.37arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1124975316152612788Rat
731168Bp154Blood pressure QTL 1543.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1103779152223964440Rat
1354623Rf46Renal function QTL 463.8blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)1111949780160574007Rat
631205Bp196Blood pressure QTL 19640.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)198879955208479939Rat
738022Anxrr13Anxiety related response QTL 134.60.00039locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of, or within a discrete space in an open field apparatus (CMO:0001514)192683681137683681Rat
10054135Gmadr2Adrenal mass QTL 21.970.0129adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)186993904131993904Rat
1641897Alcrsp1Alcohol response QTL 1response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1110389869155389869Rat
1331749Hrtrt11Heart rate QTL 112.973heart pumping trait (VT:2000009)heart rate (CMO:0000002)192683681137683681Rat
7411712Strs4Sensitivity to stroke QTL 48.7cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)187558587132558587Rat
737977Bp160Blood pressure QTL 1600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)197582336142582336Rat
1331751Bp199Blood pressure QTL 1993.60022arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1116099376191260518Rat
2293142Bp314Blood pressure QTL 314arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1101594089146594089Rat
61433Cia2Collagen induced arthritis QTL 25joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1100345976145345976Rat
724529Cm16Cardiac mass QTL 162.7heart mass (VT:0007028)calculated heart weight (CMO:0000073)196717367160111531Rat
1354606Bp246Blood pressure QTL 2463.6arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)1111949780228180370Rat
61370Mcs3Mammary carcinoma susceptibility QTL 32.15mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1111404407142582336Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 90 59 6 354 190 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000021884   ⟹   ENSRNOP00000021884
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1127,376,353 - 127,399,420 (+)Ensembl
mRatBN7.2 Ensembl1117,964,646 - 117,987,778 (+)Ensembl
Rnor_6.0 Ensembl1125,229,469 - 125,252,666 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000098605   ⟹   ENSRNOP00000094248
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1127,376,298 - 127,400,367 (+)Ensembl
mRatBN7.2 Ensembl1117,964,576 - 117,988,484 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000101373   ⟹   ENSRNOP00000077011
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1117,964,646 - 117,987,778 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000114750   ⟹   ENSRNOP00000078360
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1117,973,627 - 117,987,778 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000116662   ⟹   ENSRNOP00000085509
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1127,376,321 - 127,398,723 (+)Ensembl
mRatBN7.2 Ensembl1117,964,644 - 117,987,775 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000166776   ⟹   ENSRNOP00000104783
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1127,376,343 - 127,400,330 (+)Ensembl
RefSeq Acc Id: NM_001106341   ⟹   NP_001099811
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81127,376,353 - 127,399,551 (+)NCBI
mRatBN7.21117,964,576 - 117,987,778 (+)NCBI
Rnor_6.01125,229,487 - 125,252,669 (+)NCBI
Rnor_5.01126,338,537 - 126,361,726 (+)NCBI
RGSC_v3.41118,832,889 - 118,856,087 (+)RGD
Celera1110,219,737 - 110,242,933 (+)RGD
Sequence:
RefSeq Acc Id: XM_039108802   ⟹   XP_038964730
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81127,376,311 - 127,399,469 (+)NCBI
mRatBN7.21117,964,595 - 117,987,779 (+)NCBI
RefSeq Acc Id: XM_039108809   ⟹   XP_038964737
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81127,376,324 - 127,399,548 (+)NCBI
mRatBN7.21117,964,595 - 117,987,779 (+)NCBI
RefSeq Acc Id: NP_001099811   ⟸   NM_001106341
- UniProtKB: A6JBL4 (UniProtKB/TrEMBL),   A0A8I6AMQ5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000021884   ⟸   ENSRNOT00000021884
RefSeq Acc Id: XP_038964730   ⟸   XM_039108802
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A417 (UniProtKB/TrEMBL),   A6JBL6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038964737   ⟸   XM_039108809
- Peptide Label: isoform X2
- UniProtKB: A6JBL5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000078360   ⟸   ENSRNOT00000114750
Ensembl Acc Id: ENSRNOP00000077011   ⟸   ENSRNOT00000101373
Ensembl Acc Id: ENSRNOP00000094248   ⟸   ENSRNOT00000098605
Ensembl Acc Id: ENSRNOP00000085509   ⟸   ENSRNOT00000116662
Ensembl Acc Id: ENSRNOP00000104783   ⟸   ENSRNOT00000166776
Protein Domains
Glyoxalase/fosfomycin resistance/dioxygenase   VOC

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A197-F1-model_v2 AlphaFold D4A197 1-178 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13690098
Promoter ID:EPDNEW_R621
Type:initiation region
Name:Mcee_1
Description:methylmalonyl CoA epimerase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01125,229,563 - 125,229,623EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309966 AgrOrtholog
BioCyc Gene G2FUF-59072 BioCyc
BioCyc Pathway PROPIONMET-PWY [propanoyl CoA degradation I] BioCyc
BioCyc Pathway Image PROPIONMET-PWY BioCyc
Ensembl Genes ENSRNOG00000016327 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000021884 ENTREZGENE
  ENSRNOT00000021884.8 UniProtKB/TrEMBL
  ENSRNOT00000098605.2 UniProtKB/TrEMBL
  ENSRNOT00000116662.2 UniProtKB/TrEMBL
  ENSRNOT00000166776.1 UniProtKB/TrEMBL
Gene3D-CATH 3.10.180.10 UniProtKB/TrEMBL
InterPro Glyas_Bleomycin-R_OHBP_Dase UniProtKB/TrEMBL
  Glyas_Fos-R_dOase_dom UniProtKB/TrEMBL
  MeMalonyl-CoA_epimerase UniProtKB/TrEMBL
  MMCE/EMCE_epimerase UniProtKB/TrEMBL
  VOC UniProtKB/TrEMBL
KEGG Report rno:293829 UniProtKB/TrEMBL
NCBI Gene 293829 ENTREZGENE
PANTHER METHYLMALONYL-COA EPIMERASE UniProtKB/TrEMBL
  METHYLMALONYL-COA EPIMERASE, MITOCHONDRIAL UniProtKB/TrEMBL
Pfam Glyoxalase UniProtKB/TrEMBL
  Glyoxalase_4 UniProtKB/TrEMBL
PhenoGen Mcee PhenoGen
PROSITE VOC UniProtKB/TrEMBL
RatGTEx ENSRNOG00000016327 RatGTEx
Superfamily-SCOP SSF54593 UniProtKB/TrEMBL
UniProt A0A8I6A417 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AMQ5 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LP85_RAT UniProtKB/TrEMBL
  A6JBL4 ENTREZGENE, UniProtKB/TrEMBL
  A6JBL5 ENTREZGENE, UniProtKB/TrEMBL
  A6JBL6 ENTREZGENE, UniProtKB/TrEMBL
  D4A197_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Mcee  methylmalonyl CoA epimerase   Mcee_predicted  methylmalonyl CoA epimerase (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Mcee_predicted  methylmalonyl CoA epimerase (predicted)      Symbol and Name status set to approved 70820 APPROVED