Zfp105 (zinc finger protein 105) - Rat Genome Database

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Gene: Zfp105 (zinc finger protein 105) Rattus norvegicus
Analyze
Symbol: Zfp105
Name: zinc finger protein 105
RGD ID: 1309905
Description: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in cellular response to retinoic acid; regulation of transcription by RNA polymerase II; and spermatogenesis. Predicted to be located in perinuclear region of cytoplasm. Predicted to be active in nucleus. Orthologous to human ZNF35 (zinc finger protein 35); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC316096; zinc finger protein 35
RGD Orthologs
Human
Mouse
Bonobo
Dog
Pig
Green Monkey
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88131,444,692 - 131,456,159 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl8131,448,072 - 131,459,765 (+)EnsemblGRCr8
mRatBN7.28122,567,229 - 122,578,696 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8122,567,214 - 122,578,692 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx8128,164,012 - 128,174,873 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08126,362,959 - 126,373,820 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08124,191,181 - 124,202,180 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.08131,998,787 - 132,009,987 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8131,998,778 - 132,009,981 (+)Ensemblrn6Rnor6.0
Rnor_5.08131,153,584 - 131,164,784 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.48127,657,734 - 127,669,201 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera8121,684,379 - 121,695,727 (+)NCBICelera
RGSC_v3.18127,680,876 - 127,688,929 (+)NCBI
Cytogenetic Map8q32NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:1572646   PMID:8477855   PMID:8697448   PMID:12477932   PMID:20186958  


Genomics

Comparative Map Data
Zfp105
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88131,444,692 - 131,456,159 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl8131,448,072 - 131,459,765 (+)EnsemblGRCr8
mRatBN7.28122,567,229 - 122,578,696 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8122,567,214 - 122,578,692 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx8128,164,012 - 128,174,873 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08126,362,959 - 126,373,820 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08124,191,181 - 124,202,180 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.08131,998,787 - 132,009,987 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8131,998,778 - 132,009,981 (+)Ensemblrn6Rnor6.0
Rnor_5.08131,153,584 - 131,164,784 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.48127,657,734 - 127,669,201 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera8121,684,379 - 121,695,727 (+)NCBICelera
RGSC_v3.18127,680,876 - 127,688,929 (+)NCBI
Cytogenetic Map8q32NCBI
ZNF35
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38344,646,506 - 44,660,791 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl344,648,732 - 44,660,791 (+)Ensemblhg38GRCh38
GRCh37344,690,224 - 44,702,283 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36344,665,237 - 44,677,287 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34344,665,258 - 44,677,279NCBI
Celera344,628,226 - 44,640,276 (+)NCBICelera
Cytogenetic Map3p21.31NCBI
HuRef344,734,364 - 44,746,410 (+)NCBIHuRef
CHM1_1344,640,323 - 44,652,371 (+)NCBICHM1_1
T2T-CHM13v2.0344,662,214 - 44,676,499 (+)NCBIT2T-CHM13v2.0
Zfp105
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399122,752,105 - 122,764,325 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9122,752,137 - 122,760,093 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm389122,923,039 - 122,935,260 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9122,923,072 - 122,931,028 (+)Ensemblmm10GRCm38
MGSCv379122,832,196 - 122,840,146 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv369122,771,797 - 122,779,721 (+)NCBIMGSCv36mm8
Celera9123,376,377 - 123,384,323 (+)NCBICelera
Cytogenetic Map9F4NCBI
cM Map973.23NCBI
ZNF35
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2244,595,869 - 44,612,501 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1344,600,635 - 44,612,724 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0344,538,624 - 44,550,795 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1345,596,190 - 45,608,182 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl345,598,714 - 45,607,343 (+)EnsemblpanPan2panpan1.1
ZNF35
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12021,319 - 43,809 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2025,846 - 41,516 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2075,737 - 99,807 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02025,019 - 49,099 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2032,083 - 48,976 (-)EnsemblROS_Cfam_1.0 Ensembl
UNSW_CanFamBas_1.02087,459 - 111,536 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02046,754 - 70,834 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
ZNF35
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1327,902,558 - 27,914,479 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11327,902,503 - 27,920,494 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
ZNF35
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1226,124,883 - 6,137,710 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl226,127,829 - 6,136,515 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666041161,028,420 - 161,049,570 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Znf35
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v18114,055,402 - 114,065,746 (+)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:87
Count of miRNA genes:79
Interacting mature miRNAs:83
Transcripts:ENSRNOT00000040625
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
738011Anxrr9Anxiety related response QTL 96.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)8102413464132782436Rat
2303171Bp331Blood pressure QTL 3315.570.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)8105462581132782436Rat
634332Pia18Pristane induced arthritis QTL 184joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)884192326132782436Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)879394435132782436Rat
61437Cia6Collagen induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)891340911131690273Rat

Markers in Region
RH128432  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2195,718,880 - 95,719,085 (+)MAPPERmRatBN7.2
mRatBN7.28122,576,421 - 122,576,626 (+)MAPPERmRatBN7.2
Rnor_6.08132,007,713 - 132,007,917NCBIRnor6.0
Rnor_6.01101,230,178 - 101,230,382NCBIRnor6.0
Rnor_5.01102,295,152 - 102,295,356UniSTSRnor5.0
Rnor_5.08131,162,510 - 131,162,714UniSTSRnor5.0
RGSC_v3.4195,709,662 - 95,709,866UniSTSRGSC3.4
RGSC_v3.48127,666,927 - 127,667,131UniSTSRGSC3.4
Celera189,977,161 - 89,977,365UniSTS
Cytogenetic Map8q32UniSTS
Cytogenetic Map1q22UniSTS
RH129682  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28122,578,477 - 122,578,657 (+)MAPPERmRatBN7.2
Rnor_6.08132,009,769 - 132,009,948NCBIRnor6.0
Rnor_5.08131,164,566 - 131,164,745UniSTSRnor5.0
RGSC_v3.48127,668,983 - 127,669,162UniSTSRGSC3.4
Celera8121,695,509 - 121,695,688UniSTS
RH 3.4 Map81258.2UniSTS
Cytogenetic Map8q32UniSTS
UniSTS:496746  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28122,577,887 - 122,577,978 (+)MAPPERmRatBN7.2
Rnor_6.08132,009,179 - 132,009,269NCBIRnor6.0
Rnor_5.08131,163,976 - 131,164,066UniSTSRnor5.0
RGSC_v3.48127,668,393 - 127,668,483UniSTSRGSC3.4
Celera8121,694,919 - 121,695,009UniSTS
Cytogenetic Map8q32UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 89 59 6 353 189 11 142 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000040625   ⟹   ENSRNOP00000042236
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl8122,567,214 - 122,578,692 (+)Ensembl
Rnor_6.0 Ensembl8131,998,778 - 132,009,981 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000168577   ⟹   ENSRNOP00000109569
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl8131,448,072 - 131,459,765 (+)Ensembl
RefSeq Acc Id: NM_001012128   ⟹   NP_001012128
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88131,444,692 - 131,456,159 (+)NCBI
mRatBN7.28122,567,229 - 122,578,696 (+)NCBI
Rnor_6.08131,998,787 - 132,009,987 (+)NCBI
Rnor_5.08131,153,584 - 131,164,784 (+)NCBI
RGSC_v3.48127,657,734 - 127,669,201 (+)RGD
Celera8121,684,379 - 121,695,727 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001012128 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAB36812 (Get FASTA)   NCBI Sequence Viewer  
  AAH88185 (Get FASTA)   NCBI Sequence Viewer  
  EDL76785 (Get FASTA)   NCBI Sequence Viewer  
  EDL76786 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000109569
  ENSRNOP00000109569.1
RefSeq Acc Id: NP_001012128   ⟸   NM_001012128
- UniProtKB: Q5M881 (UniProtKB/TrEMBL),   F7FKJ4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000042236   ⟸   ENSRNOT00000040625
Ensembl Acc Id: ENSRNOP00000109569   ⟸   ENSRNOT00000168577
Protein Domains
C2H2-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5M881-F1-model_v2 AlphaFold Q5M881 1-524 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696399
Promoter ID:EPDNEW_R6924
Type:multiple initiation site
Name:Zfp105_1
Description:zinc finger protein 105
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.08131,998,773 - 131,998,833EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309905 AgrOrtholog
BioCyc Gene G2FUF-28629 BioCyc
Ensembl Genes ENSRNOG00000032919 Ensembl
  ENSRNOG00000079667 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000168577 ENTREZGENE
  ENSRNOT00000168577.1 UniProtKB/TrEMBL
Gene3D-CATH Classic Zinc Finger UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7097617 IMAGE-MGC_LOAD
  IMAGE:7367875 IMAGE-MGC_LOAD
InterPro Znf_C2H2/integrase_DNA-bd UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
KEGG Report rno:316096 UniProtKB/TrEMBL
MGC_CLONE MGC:108847 IMAGE-MGC_LOAD
  MGC:93706 IMAGE-MGC_LOAD
NCBI Gene 316096 ENTREZGENE
PANTHER ZINC FINGER AND SCAN DOMAIN-CONTAINING UniProtKB/TrEMBL
  ZINC FINGER PROTEIN ZFP2 UniProtKB/TrEMBL
Pfam zf-C2H2 UniProtKB/TrEMBL
PhenoGen Zfp105 PhenoGen
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000032919 RatGTEx
  ENSRNOG00000079667 RatGTEx
SMART ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF57667 UniProtKB/TrEMBL
UniProt A0ABK0LWY9_RAT UniProtKB/TrEMBL
  F7FKJ4 ENTREZGENE, UniProtKB/TrEMBL
  Q5M881 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Zfp105  zinc finger protein 105  Zfp105_predicted  zinc finger protein 105 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Zfp105_predicted  zinc finger protein 105 (predicted)      Symbol and Name status set to approved 70820 APPROVED