Snx19 (sorting nexin 19) - Rat Genome Database

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Gene: Snx19 (sorting nexin 19) Rattus norvegicus
Analyze
Symbol: Snx19
Name: sorting nexin 19
RGD ID: 1309857
Description: Predicted to enable phosphatidylinositol binding activity. Predicted to be involved in exocytosis and protein transport. Predicted to act upstream of or within several processes, including chondrocyte differentiation; dense core granule maturation; and insulin secretion. Predicted to be located in cytoplasm. Orthologous to human SNX19 (sorting nexin 19); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC315478; sorting nexin-19
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8837,088,142 - 37,125,317 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl837,088,191 - 37,125,264 (+)EnsemblGRCr8
mRatBN7.2828,829,881 - 28,867,600 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl828,829,886 - 28,867,061 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx832,896,451 - 32,933,015 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0831,190,858 - 31,227,422 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0829,068,313 - 29,105,324 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0831,497,034 - 31,534,077 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl831,497,639 - 31,534,077 (+)Ensemblrn6Rnor6.0
Rnor_5.0831,526,141 - 31,563,756 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4830,149,376 - 30,186,285 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera830,300,004 - 30,336,519 (+)NCBICelera
RGSC_v3.1830,158,000 - 30,192,395 (+)NCBI
Cytogenetic Map8q13NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:19877062   PMID:24843546   PMID:25148684  


Genomics

Comparative Map Data
Snx19
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8837,088,142 - 37,125,317 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl837,088,191 - 37,125,264 (+)EnsemblGRCr8
mRatBN7.2828,829,881 - 28,867,600 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl828,829,886 - 28,867,061 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx832,896,451 - 32,933,015 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0831,190,858 - 31,227,422 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0829,068,313 - 29,105,324 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0831,497,034 - 31,534,077 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl831,497,639 - 31,534,077 (+)Ensemblrn6Rnor6.0
Rnor_5.0831,526,141 - 31,563,756 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4830,149,376 - 30,186,285 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera830,300,004 - 30,336,519 (+)NCBICelera
RGSC_v3.1830,158,000 - 30,192,395 (+)NCBI
Cytogenetic Map8q13NCBI
SNX19
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811130,866,250 - 130,916,479 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11130,866,250 - 130,916,479 (-)Ensemblhg38GRCh38
GRCh3711130,736,145 - 130,786,374 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611130,250,976 - 130,291,592 (-)NCBIBuild 36Build 36hg18NCBI36
Celera11127,914,643 - 127,955,264 (-)NCBICelera
Cytogenetic Map11q24.3-q25NCBI
HuRef11126,700,502 - 126,741,119 (-)NCBIHuRef
CHM1_111130,631,931 - 130,672,553 (-)NCBICHM1_1
T2T-CHM13v2.011130,901,996 - 130,952,245 (-)NCBIT2T-CHM13v2.0
Snx19
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39930,338,284 - 30,378,437 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl930,338,404 - 30,378,029 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38930,426,988 - 30,467,141 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl930,427,108 - 30,466,733 (+)Ensemblmm10GRCm38
MGSCv37930,234,914 - 30,274,311 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36930,176,896 - 30,216,287 (+)NCBIMGSCv36mm8
Celera927,687,735 - 27,727,331 (+)NCBICelera
Cytogenetic Map9A4NCBI
cM Map916.04NCBI
Snx19
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541231,747,760 - 31,791,044 (-)Ensembl
ChiLan1.0NW_00495541231,747,519 - 31,791,022 (-)NCBIChiLan1.0ChiLan1.0
SNX19
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29131,548,955 - 131,599,228 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111132,669,158 - 132,709,818 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011125,691,537 - 125,732,206 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111129,581,876 - 129,622,517 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11129,581,876 - 129,622,517 (-)EnsemblpanPan2panpan1.1
SNX19
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.154,044,597 - 4,085,438 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl54,045,097 - 4,084,363 (+)EnsemblcanFam3CanFam3.1
ROS_Cfam_1.054,005,551 - 4,046,279 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl54,005,541 - 4,046,264 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.154,041,102 - 4,081,805 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.054,048,129 - 4,089,041 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.054,075,351 - 4,116,069 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Snx19
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947112,871,560 - 112,921,032 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365721,529,262 - 1,571,144 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365721,529,329 - 1,567,991 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SNX19
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl957,510,486 - 57,558,339 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1957,509,186 - 57,558,361 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2963,780,727 - 63,829,824 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SNX19
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11121,927,660 - 121,968,101 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1121,930,165 - 121,968,075 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660434,134,817 - 4,175,289 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Snx19
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248125,329,460 - 5,381,593 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248125,328,091 - 5,381,537 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Snx19
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1826,245,228 - 26,279,882 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Snx19
229 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:640
Count of miRNA genes:279
Interacting mature miRNAs:371
Transcripts:ENSRNOT00000020041
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357398Slep3Serum leptin concentration QTL 33.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)81799410550763951Rat
1358896Bp262Blood pressure QTL 2622.89arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)835464071107982864Rat
2317030Wbc5White blood cell count QTL 53.210.005leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)81699464261994642Rat
12880044Am9Aortic mass QTL 90.007aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)81038254055382540Rat
631648Stl5Serum triglyceride level QTL 540.0003blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)83546407171842899Rat
2301416Bp315Blood pressure QTL 3150.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)81595227960952279Rat
631842Inf1Infertility severity QTL 14.10.001seminal gland mass (VT:0010524)seminal vesicle wet weight (CMO:0001603)83154366176543661Rat
2317032Ginf2Gastrointestinal inflammation QTL 23.210.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)81296416557964165Rat
2317036Livw3Liver weight QTL 32.430.01liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)81296416557964165Rat
1358907Cm40Cardiac mass QTL 401.89heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)835464071107982864Rat
1598824Memor4Memory QTL 42.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)81799386262252873Rat
12880023Bw184Body weight QTL 1840.001body mass (VT:0001259)body weight (CMO:0000012)81038254055382540Rat
2317051Aia18Adjuvant induced arthritis QTL 182.42joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)81699464261994642Rat
1358892Kidm26Kidney mass QTL 263.69kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)835464071107982864Rat
12880028Cm103Cardiac mass QTL 1030.02heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)81038254055382540Rat
1359021Bp271Blood pressure QTL 2711.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)83412590255607752Rat
2317048Ginf1Gastrointestinal inflammation QTL 13.520.005cecum mucosa thickness (VT:0010234)enterocolitis severity score (CMO:0002138)81296416557964165Rat
2302367Slep5Serum leptin concentration QTL 53.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)81799410550763951Rat
12880025Cm102Cardiac mass QTL 1020.044heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)81038254055382540Rat

Markers in Region
RH144420  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2828,867,326 - 28,867,477 (+)MAPPERmRatBN7.2
Rnor_6.0831,534,343 - 31,534,493NCBIRnor6.0
Rnor_5.0831,563,481 - 31,563,631UniSTSRnor5.0
RGSC_v3.4830,187,401 - 30,187,551UniSTSRGSC3.4
RGSC_v3.4830,186,551 - 30,186,701UniSTSRGSC3.4
Celera830,336,785 - 30,336,935UniSTS
RH 3.4 Map8246.1UniSTS
Cytogenetic Map8q13UniSTS
BE096949  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2828,862,915 - 28,863,073 (+)MAPPERmRatBN7.2
Rnor_6.0831,529,932 - 31,530,089NCBIRnor6.0
Rnor_5.0831,559,070 - 31,559,227UniSTSRnor5.0
RGSC_v3.4830,182,140 - 30,182,297UniSTSRGSC3.4
Celera830,332,374 - 30,332,531UniSTS
RH 3.4 Map8245.0UniSTS
Cytogenetic Map8q13UniSTS
AW529649  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2828,866,303 - 28,866,454 (+)MAPPERmRatBN7.2
Rnor_6.0831,533,320 - 31,533,470NCBIRnor6.0
Rnor_5.0831,562,458 - 31,562,608UniSTSRnor5.0
RGSC_v3.4830,185,528 - 30,185,678UniSTSRGSC3.4
Celera830,335,762 - 30,335,912UniSTS
RH 3.4 Map8244.1UniSTS
Cytogenetic Map8q13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 92 59 6 356 192 11 143 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000020041   ⟹   ENSRNOP00000020041
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl837,088,191 - 37,125,264 (+)Ensembl
mRatBN7.2 Ensembl828,830,529 - 28,867,061 (+)Ensembl
Rnor_6.0 Ensembl831,497,639 - 31,534,077 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000097104   ⟹   ENSRNOP00000089305
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl837,088,191 - 37,123,537 (+)Ensembl
mRatBN7.2 Ensembl828,829,886 - 28,865,280 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000114121   ⟹   ENSRNOP00000089870
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl828,829,901 - 28,865,681 (+)Ensembl
RefSeq Acc Id: NM_001108131   ⟹   NP_001101601
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8837,088,786 - 37,125,317 (+)NCBI
mRatBN7.2828,830,529 - 28,867,061 (+)NCBI
Rnor_6.0831,497,639 - 31,534,077 (+)NCBI
Rnor_5.0831,526,141 - 31,563,756 (+)NCBI
RGSC_v3.4830,149,376 - 30,186,285 (+)RGD
Celera830,300,004 - 30,336,519 (+)RGD
Sequence:
RefSeq Acc Id: XM_006242747   ⟹   XP_006242809
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8837,088,142 - 37,124,768 (+)NCBI
mRatBN7.2828,829,882 - 28,867,600 (+)NCBI
Rnor_6.0831,497,034 - 31,531,699 (+)NCBI
Rnor_5.0831,526,141 - 31,563,756 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063265353   ⟹   XP_063121423
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8837,094,449 - 37,124,768 (+)NCBI
RefSeq Acc Id: XR_005487808
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8837,088,142 - 37,095,991 (+)NCBI
mRatBN7.2828,829,881 - 28,867,600 (+)NCBI
RefSeq Acc Id: NP_001101601   ⟸   NM_001108131
- UniProtKB: A0A8I6ABN1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006242809   ⟸   XM_006242747
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000020041   ⟸   ENSRNOT00000020041
Ensembl Acc Id: ENSRNOP00000089305   ⟸   ENSRNOT00000097104
Ensembl Acc Id: ENSRNOP00000089870   ⟸   ENSRNOT00000114121
RefSeq Acc Id: XP_063121423   ⟸   XM_063265353
- Peptide Label: isoform X2
Protein Domains
PX   PXA

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZXB9-F1-model_v2 AlphaFold D3ZXB9 1-890 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309857 AgrOrtholog
BioCyc Gene G2FUF-31278 BioCyc
Ensembl Genes ENSRNOG00000014719 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000020041 ENTREZGENE
  ENSRNOT00000020041.8 UniProtKB/TrEMBL
  ENSRNOT00000097104.2 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1520.10 UniProtKB/TrEMBL
InterPro IPR001683 UniProtKB/TrEMBL
  Phox_assoc UniProtKB/TrEMBL
  PX_dom_sf UniProtKB/TrEMBL
  SNX19_PX UniProtKB/TrEMBL
  Sorting_nexin_C UniProtKB/TrEMBL
KEGG Report rno:315478 UniProtKB/TrEMBL
NCBI Gene 315478 ENTREZGENE
PANTHER PTHR22775:SF31 UniProtKB/TrEMBL
  SORTING NEXIN UniProtKB/TrEMBL
Pfam Nexin_C UniProtKB/TrEMBL
  PF00787 UniProtKB/TrEMBL
  PXA UniProtKB/TrEMBL
PhenoGen Snx19 PhenoGen
PROSITE PS50195 UniProtKB/TrEMBL
  PXA UniProtKB/TrEMBL
RatGTEx ENSRNOG00000014719 RatGTEx
SMART PXA UniProtKB/TrEMBL
  SM00312 UniProtKB/TrEMBL
Superfamily-SCOP 64268 UniProtKB/TrEMBL
UniProt A0A8I6ABN1 ENTREZGENE, UniProtKB/TrEMBL
  A6JYF1_RAT UniProtKB/TrEMBL
  D3ZXB9_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Snx19  sorting nexin 19   Snx19_predicted  sorting nexin 19 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Snx19_predicted  sorting nexin 19 (predicted)      Symbol and Name status set to approved 70820 APPROVED