Dock7 (dedicator of cytokinesis 7) - Rat Genome Database

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Gene: Dock7 (dedicator of cytokinesis 7) Rattus norvegicus
Analyze
Symbol: Dock7
Name: dedicator of cytokinesis 7
RGD ID: 1309790
Description: Predicted to enable GTPase activator activity; guanyl-nucleotide exchange factor activity; and small GTPase binding activity. Predicted to be involved in several processes, including Rac protein signal transduction; negative regulation of cold-induced thermogenesis; and nervous system development. Predicted to act upstream of or within hematopoietic progenitor cell differentiation and pigmentation. Predicted to be part of COP9 signalosome. Predicted to be active in neuromuscular junction. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 23. Orthologous to human DOCK7 (dedicator of cytokinesis 7); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: dedicator of cytokinesis protein 7; LOC313388; MGC189434
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85118,714,863 - 118,898,362 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5118,714,863 - 118,898,335 (-)EnsemblGRCr8
mRatBN7.25113,599,371 - 113,782,871 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5113,600,198 - 113,782,813 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5116,173,874 - 116,331,721 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05117,899,210 - 118,057,047 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05117,961,741 - 118,119,584 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05117,595,194 - 117,780,844 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5117,596,136 - 117,780,777 (-)Ensemblrn6Rnor6.0
Rnor_5.05121,536,701 - 121,718,634 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45119,377,149 - 119,535,973 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5112,163,983 - 112,318,639 (-)NCBICelera
Cytogenetic Map5q33NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,4'-trichlorobiphenyl  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
aflatoxin M1  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
amphetamine  (EXP)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsenite(3-)  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
beta-lapachone  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butanal  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP)
caffeine  (ISO)
CGP 52608  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
diethylstilbestrol  (ISO)
dorsomorphin  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
enzyme inhibitor  (ISO)
flutamide  (EXP)
FR900359  (ISO)
gallic acid  (ISO)
hexadecanoic acid  (ISO)
indometacin  (ISO)
ivermectin  (ISO)
lovastatin  (ISO)
mercury dibromide  (ISO)
methapyrilene  (EXP)
methimazole  (EXP)
methylmercury chloride  (ISO)
p-chloromercuribenzoic acid  (ISO)
paracetamol  (EXP,ISO)
PCB138  (ISO)
perfluorooctanoic acid  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
sulfadimethoxine  (EXP)
thapsigargin  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
warfarin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Altered thermogenesis and impaired bone remodeling in Misty mice. Motyl KJ, etal., J Bone Miner Res. 2013 Sep;28(9):1885-97. doi: 10.1002/jbmr.1943.
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:2379821   PMID:12477932   PMID:16982419   PMID:18426980   PMID:18850735   PMID:21423176   PMID:22158624   PMID:22475431   PMID:22842144   PMID:24029230   PMID:27018747   PMID:31505169  


Genomics

Comparative Map Data
Dock7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85118,714,863 - 118,898,362 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5118,714,863 - 118,898,335 (-)EnsemblGRCr8
mRatBN7.25113,599,371 - 113,782,871 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5113,600,198 - 113,782,813 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5116,173,874 - 116,331,721 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05117,899,210 - 118,057,047 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05117,961,741 - 118,119,584 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05117,595,194 - 117,780,844 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5117,596,136 - 117,780,777 (-)Ensemblrn6Rnor6.0
Rnor_5.05121,536,701 - 121,718,634 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45119,377,149 - 119,535,973 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5112,163,983 - 112,318,639 (-)NCBICelera
Cytogenetic Map5q33NCBI
DOCK7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38162,454,726 - 62,688,386 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl162,454,298 - 62,688,464 (-)Ensemblhg38GRCh38
GRCh37162,920,397 - 63,154,057 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36162,692,985 - 62,926,557 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34162,632,417 - 62,865,990NCBI
Celera161,209,606 - 61,442,836 (-)NCBICelera
Cytogenetic Map1p31.3NCBI
HuRef161,032,437 - 61,265,993 (-)NCBIHuRef
CHM1_1163,035,730 - 63,269,026 (-)NCBICHM1_1
T2T-CHM13v2.0162,333,313 - 62,566,591 (-)NCBIT2T-CHM13v2.0
Dock7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39498,824,669 - 99,019,190 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl498,824,908 - 99,009,152 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38498,936,659 - 99,130,953 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl498,936,671 - 99,120,915 (-)Ensemblmm10GRCm38
MGSCv37498,603,356 - 98,787,606 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36498,428,693 - 98,612,878 (-)NCBIMGSCv36mm8
Celera497,303,728 - 97,492,465 (-)NCBICelera
Cytogenetic Map4C6NCBI
cM Map445.6NCBI
Dock7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542327,044,341 - 27,233,710 (+)Ensembl
ChiLan1.0NW_00495542327,043,621 - 27,233,710 (+)NCBIChiLan1.0ChiLan1.0
DOCK7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21164,163,998 - 164,396,907 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11163,313,398 - 163,546,558 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0161,713,217 - 61,946,371 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1163,528,826 - 63,760,513 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl163,529,227 - 63,740,970 (-)EnsemblpanPan2panpan1.1
DOCK7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1547,435,209 - 47,653,312 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl547,462,224 - 47,653,163 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha547,495,341 - 47,714,450 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0547,618,819 - 47,837,750 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl547,618,797 - 47,837,603 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1547,574,121 - 47,792,708 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0547,519,806 - 47,739,083 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0547,782,016 - 48,001,146 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Dock7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505875,846,153 - 76,038,630 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936692162,390 - 353,721 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936692161,979 - 354,028 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DOCK7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6149,748,036 - 149,972,168 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.16149,745,375 - 149,971,853 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26138,013,920 - 138,172,803 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DOCK7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12070,371,775 - 70,599,311 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2070,372,534 - 70,598,614 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603346,854,700 - 47,083,061 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dock7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474231,189,852 - 31,390,478 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474231,189,890 - 31,390,284 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Dock7
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1155,405,171 - 55,575,642 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Dock7
1018 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:366
Count of miRNA genes:190
Interacting mature miRNAs:227
Transcripts:ENSRNOT00000011405, ENSRNOT00000065112
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357396Bw44Body weight QTL 444.19body mass (VT:0001259)body weight (CMO:0000012)573779642118779642Rat
1331796Thshl2Thyroid stimulating hormone level QTL 22.3blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)5102105698152749382Rat
2303586Gluco52Glucose level QTL 522blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)5100826632145826632Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)544924861153890773Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5116702075161702075Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)538207390136631402Rat
1298070Scl18Serum cholesterol level QTL 183.7blood LDL cholesterol amount (VT:0000181)calculated plasma low density lipoprotein cholesterol level (CMO:0001245)584630798129630798Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)599905133172190305Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)548523123134369373Rat
2302381Bw84Body weight QTL 844.47body mass (VT:0001259)body mass index (BMI) (CMO:0000105)573779642118779642Rat
1357402Bw46Body weight QTL 464.47body mass (VT:0001259)body mass index (BMI) (CMO:0000105)573779642118779642Rat
1298077Bp157Blood pressure QTL 157arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5114474223121056531Rat
7411582Foco3Food consumption QTL 37.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)592583776137583776Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)565089051166764498Rat
1598859Cm66Cardiac mass QTL 662heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)584630798129630798Rat
7207486Bss109Bone structure and strength QTL 109femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)5112142946157142946Rat
7207481Bss106Bone structure and strength QTL 1067.9femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5112142946157142946Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5110770739155770739Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)551657967166600247Rat
1549838Bss4Bone structure and strength QTL 49.2femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)5112142946157142946Rat
1582212Livw2Liver weight QTL 23.50.0004liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)5104018576124314782Rat
7411564Bw135Body weight QTL 1350.001body mass (VT:0001259)body weight gain (CMO:0000420)592583776137583776Rat
8657050Bw146Body weight QTL 14619.840.001body mass (VT:0001259)body weight gain (CMO:0000420)598972960143972960Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555124766172190305Rat
7411601Foco12Food consumption QTL 1219.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)592583776137583776Rat
2303618Vencon1Ventilatory control QTL 13.8respiration trait (VT:0001943)oxygen consumption (CMO:0002169)5100826632145826632Rat
2317056Wbc3White blood cell count QTL 32.510.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)5111236572156236572Rat
1598846Bp293Blood pressure QTL 2933.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)584630798129630798Rat
7394710Emca12Estrogen-induced mammary cancer QTL 12mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)594034903139034903Rat
1598847Cm62Cardiac mass QTL 623.4heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5114131300159131300Rat
1358909Kidm25Kidney mass QTL 251.87kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)595062526133270832Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)560601597137492949Rat
7207488Bss110Bone structure and strength QTL 18.4femur strength trait (VT:0010010)femur stiffness (CMO:0001674)5112142946157142946Rat
8694441Bw169Body weight QTL 16917.610.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)5116702075161702075Rat
7207491Bss112Bone structure and strength QTL 1127femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)5112142946157142946Rat
8694389Bw160Body weight QTL 1606.170.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)5116702075161702075Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)536460764136631402Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)574335621156302135Rat
1600362Mcs19Mammary carcinoma susceptibility QTL 192.5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)582032155127032155Rat
8694198Abfw3Abdominal fat weight QTL 316.130.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)5116702075161702075Rat
1298086Bp156Blood pressure QTL 156arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)589369373134369373Rat
2306971Anxrr21Anxiety related response QTL 219.47fear/anxiety-related behavior trait (VT:1000241)number of entries into a discrete space in an experimental apparatus (CMO:0000960)570969494136328156Rat
1298089Scl14Serum cholesterol level QTL 145.80.0004blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5114131300159131300Rat
1358895Bp254Blood pressure QTL 2543.60.0003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)597492524133270832Rat
2312671Scl64Serum cholesterol level QTL 640.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)573779642118779642Rat
6903316Bw113Body weight QTL 11320.0103body mass (VT:0001259)body weight (CMO:0000012)592881678137881678Rat
1358889Bp261Blood pressure QTL 2612.86arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)595062526133270832Rat
1358187Emca1Estrogen-induced mammary cancer QTL 14.4mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)5104262817153890625Rat

Markers in Region
RH131293  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr85118,826,103 - 118,826,321 (+)Marker Load Pipeline
mRatBN7.25113,710,616 - 113,710,834 (+)MAPPERmRatBN7.2
Rnor_6.05117,706,380 - 117,706,597NCBIRnor6.0
Rnor_5.05121,647,177 - 121,647,394UniSTSRnor5.0
RGSC_v3.45119,487,264 - 119,487,481UniSTSRGSC3.4
Celera5112,271,625 - 112,271,842UniSTS
RH 3.4 Map5789.9UniSTS
Cytogenetic Map5q33UniSTS
RH129449  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr85118,819,021 - 118,820,003 (+)Marker Load Pipeline
mRatBN7.25113,703,534 - 113,704,516 (+)MAPPERmRatBN7.2
Rnor_6.05117,699,298 - 117,700,279NCBIRnor6.0
Rnor_5.05121,640,095 - 121,641,076UniSTSRnor5.0
RGSC_v3.45119,480,182 - 119,481,163UniSTSRGSC3.4
Celera5112,264,404 - 112,265,524UniSTS
RH 3.4 Map5793.0UniSTS
Cytogenetic Map5q33UniSTS
BF386383  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr85118,731,054 - 118,731,252 (+)Marker Load Pipeline
mRatBN7.25113,615,563 - 113,615,761 (+)MAPPERmRatBN7.2
Rnor_6.05117,611,502 - 117,611,699NCBIRnor6.0
Rnor_5.05121,553,009 - 121,553,206UniSTSRnor5.0
RGSC_v3.45119,392,515 - 119,392,712UniSTSRGSC3.4
Celera5112,179,347 - 112,179,544UniSTS
RH 3.4 Map5793.0UniSTS
Cytogenetic Map5q33UniSTS
RH135495  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25113,703,231 - 113,703,328 (+)MAPPERmRatBN7.2
Rnor_6.05117,698,995 - 117,699,091NCBIRnor6.0
Rnor_5.05121,639,792 - 121,639,888UniSTSRnor5.0
RGSC_v3.45119,479,879 - 119,479,975UniSTSRGSC3.4
Celera5112,264,101 - 112,264,197UniSTS
Cytogenetic Map5q33UniSTS
AL009364  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25113,751,250 - 113,751,399 (+)MAPPERmRatBN7.2
Rnor_6.05117,746,911 - 117,747,059NCBIRnor6.0
Rnor_5.05121,687,790 - 121,687,938UniSTSRnor5.0
Celera5112,312,261 - 112,312,409UniSTS
Cytogenetic Map5q33UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 90 59 6 354 190 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001415885 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001415886 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006238429 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008763869 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008763870 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287643 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287644 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287645 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287646 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287647 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287648 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287649 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287650 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287651 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC167079 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ124295 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000011405   ⟹   ENSRNOP00000011405
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5118,718,027 - 118,873,120 (-)Ensembl
mRatBN7.2 Ensembl5113,602,535 - 113,757,622 (-)Ensembl
Rnor_6.0 Ensembl5117,596,136 - 117,754,571 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000065112   ⟹   ENSRNOP00000063286
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5118,714,863 - 118,898,335 (-)Ensembl
mRatBN7.2 Ensembl5113,600,198 - 113,757,927 (-)Ensembl
Rnor_6.0 Ensembl5117,596,138 - 117,612,123 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000081971   ⟹   ENSRNOP00000072637
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5118,714,863 - 118,898,335 (-)Ensembl
mRatBN7.2 Ensembl5113,600,198 - 113,782,813 (-)Ensembl
Rnor_6.0 Ensembl5117,596,341 - 117,780,777 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000100273   ⟹   ENSRNOP00000089895
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5118,714,863 - 118,898,335 (-)Ensembl
mRatBN7.2 Ensembl5113,602,535 - 113,757,716 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000156393   ⟹   ENSRNOP00000098970
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5118,714,863 - 118,898,335 (-)Ensembl
RefSeq Acc Id: NM_001415885   ⟹   NP_001402814
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85118,714,863 - 118,898,335 (-)NCBI
mRatBN7.25113,599,371 - 113,782,841 (-)NCBI
RefSeq Acc Id: NM_001415886   ⟹   NP_001402815
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85118,714,863 - 118,898,335 (-)NCBI
mRatBN7.25113,599,371 - 113,782,841 (-)NCBI
RefSeq Acc Id: XM_063287643   ⟹   XP_063143713
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85118,715,690 - 118,898,337 (-)NCBI
RefSeq Acc Id: XM_063287644   ⟹   XP_063143714
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85118,715,690 - 118,898,337 (-)NCBI
RefSeq Acc Id: XM_063287645   ⟹   XP_063143715
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85118,715,690 - 118,898,337 (-)NCBI
RefSeq Acc Id: XM_063287646   ⟹   XP_063143716
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85118,715,690 - 118,898,337 (-)NCBI
RefSeq Acc Id: XM_063287647   ⟹   XP_063143717
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85118,715,690 - 118,898,362 (-)NCBI
RefSeq Acc Id: XM_063287648   ⟹   XP_063143718
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85118,755,192 - 118,898,337 (-)NCBI
RefSeq Acc Id: XM_063287649   ⟹   XP_063143719
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85118,715,690 - 118,781,368 (-)NCBI
RefSeq Acc Id: XM_063287650   ⟹   XP_063143720
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85118,801,786 - 118,898,337 (-)NCBI
RefSeq Acc Id: XM_063287651   ⟹   XP_063143721
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85118,715,690 - 118,898,337 (-)NCBI
Ensembl Acc Id: ENSRNOP00000063286   ⟸   ENSRNOT00000065112
Ensembl Acc Id: ENSRNOP00000072637   ⟸   ENSRNOT00000081971
Ensembl Acc Id: ENSRNOP00000011405   ⟸   ENSRNOT00000011405
Ensembl Acc Id: ENSRNOP00000089895   ⟸   ENSRNOT00000100273
RefSeq Acc Id: NP_001402815   ⟸   NM_001415886
- Peptide Label: isoform 2
- UniProtKB: F6PUC8 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001402814   ⟸   NM_001415885
- Peptide Label: isoform 1
- UniProtKB: A0A0G2K3H2 (UniProtKB/TrEMBL),   A0A8I6ACL2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063143717   ⟸   XM_063287647
- Peptide Label: isoform X5
- UniProtKB: A0A8I6ACL2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063143721   ⟸   XM_063287651
- Peptide Label: isoform X9
- UniProtKB: F6PUC8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063143716   ⟸   XM_063287646
- Peptide Label: isoform X4
- UniProtKB: F6PUC8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063143714   ⟸   XM_063287644
- Peptide Label: isoform X2
- UniProtKB: F6PUC8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063143715   ⟸   XM_063287645
- Peptide Label: isoform X3
- UniProtKB: F6PUC8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063143713   ⟸   XM_063287643
- Peptide Label: isoform X1
- UniProtKB: A0A8I6ACL2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063143719   ⟸   XM_063287649
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063143718   ⟸   XM_063287648
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063143720   ⟸   XM_063287650
- Peptide Label: isoform X8
Ensembl Acc Id: ENSRNOP00000098970   ⟸   ENSRNOT00000156393
Protein Domains
C2 DOCK-type   DOCKER

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K3H2-F1-model_v2 AlphaFold A0A0G2K3H2 1-2129 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693860
Promoter ID:EPDNEW_R4379
Type:initiation region
Name:Dock7_1
Description:dedicator of cytokinesis 7
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05117,780,792 - 117,780,852EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309790 AgrOrtholog
BioCyc Gene G2FUF-40581 BioCyc
Ensembl Genes ENSRNOG00000008298 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000011405.10 UniProtKB/TrEMBL
  ENSRNOT00000065112 ENTREZGENE
  ENSRNOT00000065112.4 UniProtKB/TrEMBL
  ENSRNOT00000081971 ENTREZGENE
  ENSRNOT00000081971.3 UniProtKB/TrEMBL
  ENSRNOT00000100273 ENTREZGENE
  ENSRNOT00000100273.2 UniProtKB/TrEMBL
  ENSRNOT00000156393 ENTREZGENE
  ENSRNOT00000156393.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.58.740 UniProtKB/TrEMBL
  1.25.40.410 UniProtKB/TrEMBL
  2.60.40.150 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7317229 IMAGE-MGC_LOAD
InterPro C2_Dock-C UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  DHR-2 UniProtKB/TrEMBL
  DOCK UniProtKB/TrEMBL
  DOCK-C2 UniProtKB/TrEMBL
  DOCK_C/D_N UniProtKB/TrEMBL
  DOCK_C_lobe_A UniProtKB/TrEMBL
  DOCK_C_lobe_C UniProtKB/TrEMBL
  DOCKER_Lobe_A UniProtKB/TrEMBL
  DOCKER_Lobe_B UniProtKB/TrEMBL
  DOCKER_Lobe_C UniProtKB/TrEMBL
MGC_CLONE MGC:189434 IMAGE-MGC_LOAD
NCBI Gene 313388 ENTREZGENE
PANTHER DEDICATOR OF CYTOKINESIS PROTEIN 7 UniProtKB/TrEMBL
  PTHR23317 UniProtKB/TrEMBL
Pfam Ded_cyto UniProtKB/TrEMBL
  DHR-2_Lobe_B UniProtKB/TrEMBL
  DHR-2_Lobe_C UniProtKB/TrEMBL
  DOCK-C2 UniProtKB/TrEMBL
  DUF3398 UniProtKB/TrEMBL
PhenoGen Dock7 PhenoGen
PROSITE DHR_1 UniProtKB/TrEMBL
  DHR_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000008298 RatGTEx
UniProt A0A0G2K3H2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ACL2 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0KWW4_RAT UniProtKB/TrEMBL
  B2RZA1_RAT UniProtKB/TrEMBL
  F1LRS2_RAT UniProtKB/TrEMBL
  F6PUC8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Dock7  dedicator of cytokinesis 7  Dock7_predicted  dedicator of cytokinesis 7 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Dock7_predicted  dedicator of cytokinesis 7 (predicted)      Symbol and Name status set to approved 70820 APPROVED