C19h16orf74 (similar to human chromosome 16 open reading frame 74) - Rat Genome Database

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Gene: C19h16orf74 (similar to human chromosome 16 open reading frame 74) Rattus norvegicus
Analyze
Symbol: C19h16orf74
Name: similar to human chromosome 16 open reading frame 74
RGD ID: 1309651
Description: Orthologous to human C16orf74 (chromosome 16 open reading frame 74); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC361424; RGD1309651; similar to 1190005I06Rik protein; uncharacterized protein C16orf74 homolog
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81965,568,997 - 65,594,994 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1965,568,997 - 65,595,460 (-)EnsemblGRCr8
mRatBN7.21948,660,288 - 48,686,287 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1948,660,288 - 48,686,349 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1955,454,519 - 55,480,536 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01956,135,287 - 56,161,286 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01958,349,131 - 58,375,582 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01954,184,554 - 54,210,872 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1954,184,946 - 54,210,515 (-)Ensemblrn6Rnor6.0
Rnor_5.01964,906,438 - 64,931,464 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41950,963,265 - 50,989,667 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1947,913,225 - 47,939,423 (-)NCBICelera
RGSC_v3.11950,968,145 - 50,994,344 (-)NCBI
Cytogenetic Map19q12NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
C19h16orf74
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81965,568,997 - 65,594,994 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1965,568,997 - 65,595,460 (-)EnsemblGRCr8
mRatBN7.21948,660,288 - 48,686,287 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1948,660,288 - 48,686,349 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1955,454,519 - 55,480,536 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01956,135,287 - 56,161,286 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01958,349,131 - 58,375,582 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01954,184,554 - 54,210,872 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1954,184,946 - 54,210,515 (-)Ensemblrn6Rnor6.0
Rnor_5.01964,906,438 - 64,931,464 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41950,963,265 - 50,989,667 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1947,913,225 - 47,939,423 (-)NCBICelera
RGSC_v3.11950,968,145 - 50,994,344 (-)NCBI
Cytogenetic Map19q12NCBI
C16orf74
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381685,707,517 - 85,751,096 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1685,690,084 - 85,751,129 (-)Ensemblhg38GRCh38
GRCh371685,741,123 - 85,784,702 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361684,298,624 - 84,342,190 (-)NCBIBuild 36Build 36hg18NCBI36
Celera1670,044,265 - 70,087,824 (-)NCBICelera
Cytogenetic Map16q24.1NCBI
HuRef1671,483,238 - 71,526,434 (-)NCBIHuRef
CHM1_11687,152,497 - 87,196,246 (-)NCBICHM1_1
T2T-CHM13v2.01691,773,042 - 91,816,616 (-)NCBIT2T-CHM13v2.0
1190005I06Rik
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398121,335,341 - 121,361,129 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8121,335,341 - 121,374,371 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm388120,608,602 - 120,634,390 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8120,608,602 - 120,647,632 (-)Ensemblmm10GRCm38
MGSCv378123,132,502 - 123,158,282 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv368123,494,579 - 123,520,359 (-)NCBIMGSCv36mm8
MGSCv368120,639,707 - 120,665,625 (-)NCBIMGSCv36mm8
Celera8124,824,261 - 124,844,288 (-)NCBICelera
Cytogenetic Map8E1NCBI
cM Map869.92NCBI
CUNH16orf74
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955541824,183 - 843,420 (-)Ensembl
ChiLan1.0NW_004955541824,381 - 843,420 (-)NCBIChiLan1.0ChiLan1.0
C18H16orf74
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21895,457,645 - 95,501,855 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan116101,374,921 - 101,419,111 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01666,374,434 - 66,418,478 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11685,711,556 - 85,755,671 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1685,694,710 - 85,755,671 (-)EnsemblpanPan2panpan1.1
C5H16orf74
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1566,945,022 - 66,969,301 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl566,947,136 - 66,979,907 (+)EnsemblcanFam3CanFam3.1
CUNH16orf74
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934926,976,740 - 26,998,629 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366412,696,184 - 2,752,057 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366412,730,252 - 2,752,176 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
C6H16orf74
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl63,166,929 - 3,217,327 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.163,156,781 - 3,211,165 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.263,490,493 - 3,520,510 (+)NCBISscrofa10.2Sscrofa10.2susScr3
C5H16orf74
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1571,114,015 - 71,158,207 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660474,581,633 - 4,626,465 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
CUNH16orf74
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247462,124,160 - 2,141,567 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247462,119,090 - 2,144,239 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
C17H16orf74
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11740,249,493 - 40,276,018 (-)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:66
Count of miRNA genes:62
Interacting mature miRNAs:66
Transcripts:ENSRNOT00000023721
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631840Niddm38Non-insulin dependent diabetes mellitus QTL 383.86blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)191032907674246245Rat
724546Kidm3Kidney mass QTL 33.1kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)194622677874246245Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)193236531174246245Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)193628974246245Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)192409397369093973Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191083361874246245Rat
2303628Vencon9Ventilatory control QTL 90.005respiration trait (VT:0001943)minute ventilation (CMO:0000132)192318858668188586Rat
2313395Anxrr26Anxiety related response QTL 26aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)194438513474246245Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)193253961574246245Rat
5135224Leukc1Leukocyte quantity QTL 1eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)196124916174246245Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)193177788874246245Rat
1554318Bmd5Bone mineral density QTL 512.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)192318858668188586Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19219431774246245Rat
1549835Tcas7Tongue tumor susceptibility QTL 70.001tongue integrity trait (VT:0010553)squamous cell carcinoma of the head and neck tumor number (CMO:0001876)194172254674246245Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19219431774246245Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 66 155 83 82 51 85 51 6 338 184 11 128 79 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000023721   ⟹   ENSRNOP00000023721
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1965,568,997 - 65,594,994 (-)Ensembl
mRatBN7.2 Ensembl1948,660,288 - 48,686,349 (-)Ensembl
Rnor_6.0 Ensembl1954,184,946 - 54,210,515 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000148710   ⟹   ENSRNOP00000102540
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1965,568,997 - 65,595,460 (-)Ensembl
RefSeq Acc Id: NM_001400990   ⟹   NP_001387919
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81965,568,997 - 65,594,994 (-)NCBI
mRatBN7.21948,660,288 - 48,686,287 (-)NCBI
RefSeq Acc Id: XM_063278148   ⟹   XP_063134218
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81965,568,997 - 65,578,585 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001387919 (Get FASTA)   NCBI Sequence Viewer  
  XP_063134218 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL92704 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000023721.7
  ENSRNOP00000102540.1
Ensembl Acc Id: ENSRNOP00000023721   ⟸   ENSRNOT00000023721
RefSeq Acc Id: NP_001387919   ⟸   NM_001400990
- UniProtKB: D3ZSX5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063134218   ⟸   XM_063278148
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000102540   ⟸   ENSRNOT00000148710

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZSX5-F1-model_v2 AlphaFold D3ZSX5 1-111 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701200
Promoter ID:EPDNEW_R11718
Type:single initiation site
Name:RGD1309651_1
Description:similar to 1190005I06Rik protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01954,210,551 - 54,210,611EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309651 AgrOrtholog
BioCyc Gene G2FUF-5475 BioCyc
Ensembl Genes ENSRNOG00000017646 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000023721.8 UniProtKB/TrEMBL
  ENSRNOT00000148710.1 UniProtKB/TrEMBL
InterPro DUF4597 UniProtKB/TrEMBL
NCBI Gene 361424 ENTREZGENE
PANTHER PTHR37455 UniProtKB/TrEMBL
  SIMILAR TO 1190005I06RIK PROTEIN UniProtKB/TrEMBL
Pfam DUF4597 UniProtKB/TrEMBL
PhenoGen C19h16orf74 PhenoGen
RatGTEx ENSRNOG00000017646 RatGTEx
UniProt A0ABK0LN97_RAT UniProtKB/TrEMBL
  D3ZSX5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 C19h16orf74   similar to human chromosome 16 open reading frame 74  RGD1309651  similar to 1190005I06Rik protein  Symbol and Name Changed 1299863 APPROVED
2008-04-30 RGD1309651  similar to 1190005I06Rik protein   RGD1309651_predicted  similar to 1190005I06Rik protein (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-20 RGD1309651_predicted  similar to 1190005I06Rik protein (predicted)  LOC361424_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC361424_predicted  similar to 1190005I06Rik protein (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL