Gene: Tmem185b (transmembrane protein 185B) Rattus norvegicus
Analyze
Symbol:
Tmem185b
Name:
transmembrane protein 185B
RGD ID:
1309602
Description:
Predicted to be located in membrane. Orthologous to human TMEM185B (transmembrane protein 185B); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
LOC304731; RGD1309602; similar to RIKEN cDNA 2500001K11
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 13 33,200,329 - 33,203,660 (+) NCBI GRCr8 GRCr8 GRCr8 GRCr8 Ensembl 13 33,198,929 - 33,204,091 (+) Ensembl GRCr8 mRatBN7.2 13 30,647,533 - 30,650,864 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 13 30,647,482 - 30,650,858 (+) Ensembl mRatBN7.2 UTH_Rnor_SHR_Utx 13 33,228,893 - 33,232,226 (+) NCBI UTH_Rnor_SHR_Utx UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 13 34,516,732 - 34,520,065 (+) NCBI UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 13 31,790,854 - 31,794,186 (+) NCBI UTH_Rnor_WKY_Bbb_1.0 UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 13 35,554,621 - 35,557,952 (+) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 13 35,554,964 - 35,556,016 (+) Ensembl rn6 Rnor6.0 Rnor_5.0 13 40,669,220 - 40,672,564 (+) NCBI Rnor_5.0 Rnor_5.0 rn5 RGSC_v3.4 13 32,276,974 - 32,279,005 (+) NCBI RGSC_v3.4 RGSC_v3.4 rn4 Celera 13 30,543,175 - 30,546,506 (+) NCBI Celera RGSC_v3.1 13 32,280,108 - 32,281,829 (+) NCBI Cytogenetic Map 13 q11 NCBI
JBrowse:
Only show annotations with direct experimental evidence (0 objects hidden)
Tmem185b Rat (+)-schisandrin B multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of TMEM185B mRNA] CTD PMID:31150632 Tmem185b Rat (S)-colchicine decreases expression ISO TMEM185B (Homo sapiens) 6480464 Colchicine results in decreased expression of TMEM185B mRNA CTD PMID:24211769 Tmem185b Rat 17beta-estradiol increases expression ISO TMEM185B (Homo sapiens) 6480464 Estradiol results in increased expression of TMEM185B mRNA CTD PMID:31614463 Tmem185b Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Tmem185b (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of TMEM185B mRNA CTD PMID:21570461|PMID:24680724 Tmem185b Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of TMEM185B mRNA CTD PMID:33387578 Tmem185b Rat 2,3,7,8-Tetrachlorodibenzofuran increases expression EXP 6480464 2,3,7,8-tetrachlorodibenzofuran results in increased expression of TMEM185B mRNA CTD PMID:32109520 Tmem185b Rat adenine decreases expression ISO TMEM185B (Homo sapiens) 6480464 Adenine results in decreased expression of TMEM185B mRNA CTD PMID:24211769 Tmem185b Rat aflatoxin B1 affects expression ISO TMEM185B (Homo sapiens) 6480464 Aflatoxin B1 affects the expression of TMEM185B protein CTD PMID:20106945 Tmem185b Rat all-trans-retinoic acid decreases expression ISO TMEM185B (Homo sapiens) 6480464 Tretinoin results in decreased expression of TMEM185B mRNA CTD PMID:33167477 Tmem185b Rat atrazine affects methylation EXP 6480464 Atrazine affects the methylation of TMEM185B gene CTD PMID:28931070 Tmem185b Rat avobenzone decreases expression ISO TMEM185B (Homo sapiens) 6480464 avobenzone results in decreased expression of TMEM185B mRNA CTD PMID:31016361 Tmem185b Rat benzene increases expression ISO Tmem185b (Mus musculus) 6480464 Benzene results in increased expression of TMEM185B mRNA CTD PMID:37084897 Tmem185b Rat benzo[a]pyrene increases expression ISO TMEM185B (Homo sapiens) 6480464 Benzo(a)pyrene results in increased expression of TMEM185B mRNA CTD PMID:20106945|PMID:21632981|PMID:32234424 Tmem185b Rat bisphenol A decreases methylation ISO Tmem185b (Mus musculus) 6480464 bisphenol A results in decreased methylation of TMEM185B promoter CTD PMID:27312807 Tmem185b Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of TMEM185B mRNA CTD PMID:30816183|PMID:32528016 Tmem185b Rat Butylbenzyl phthalate increases methylation ISO Tmem185b (Mus musculus) 6480464 butylbenzyl phthalate results in increased methylation of TMEM185B promoter CTD PMID:28392331 Tmem185b Rat carbon nanotube increases expression ISO Tmem185b (Mus musculus) 6480464 Nanotubes, Carbon results in increased expression of TMEM185B mRNA CTD PMID:25554681 Tmem185b Rat CGP 52608 multiple interactions ISO TMEM185B (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to TMEM185B gene] CTD PMID:28238834 Tmem185b Rat cisplatin decreases expression ISO TMEM185B (Homo sapiens) 6480464 Cisplatin results in decreased expression of TMEM185B mRNA CTD PMID:24211769 Tmem185b Rat cobalt dichloride decreases expression ISO TMEM185B (Homo sapiens) 6480464 cobaltous chloride results in decreased expression of TMEM185B mRNA CTD PMID:19320972 Tmem185b Rat cyclosporin A increases expression ISO TMEM185B (Homo sapiens) 6480464 Cyclosporine results in increased expression of TMEM185B mRNA CTD PMID:20106945|PMID:21632981 Tmem185b Rat DDE increases expression ISO TMEM185B (Homo sapiens) 6480464 Dichlorodiphenyl Dichloroethylene results in increased expression of TMEM185B mRNA CTD PMID:38568856 Tmem185b Rat dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of TMEM185B mRNA CTD PMID:21266533 Tmem185b Rat dibutyl phthalate decreases expression EXP 6480464 Dibutyl Phthalate results in decreased expression of TMEM185B mRNA CTD PMID:21266533 Tmem185b Rat dorsomorphin multiple interactions ISO TMEM185B (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... CTD PMID:27188386 Tmem185b Rat doxorubicin decreases expression ISO TMEM185B (Homo sapiens) 6480464 Doxorubicin results in decreased expression of TMEM185B mRNA CTD PMID:29803840 Tmem185b Rat endosulfan increases expression EXP 6480464 Endosulfan results in increased expression of TMEM185B mRNA CTD PMID:29391264 Tmem185b Rat ethyl methanesulfonate decreases expression ISO TMEM185B (Homo sapiens) 6480464 Ethyl Methanesulfonate results in decreased expression of TMEM185B mRNA CTD PMID:24211769 Tmem185b Rat ethyl methanesulfonate increases expression ISO TMEM185B (Homo sapiens) 6480464 Ethyl Methanesulfonate results in increased expression of TMEM185B mRNA CTD PMID:23649840 Tmem185b Rat etoposide decreases expression ISO TMEM185B (Homo sapiens) 6480464 Etoposide results in decreased expression of TMEM185B mRNA CTD PMID:24211769 Tmem185b Rat flutamide increases expression EXP 6480464 Flutamide results in increased expression of TMEM185B mRNA CTD PMID:24136188 Tmem185b Rat folic acid decreases expression ISO Tmem185b (Mus musculus) 6480464 Folic Acid results in decreased expression of TMEM185B mRNA CTD PMID:25629700 Tmem185b Rat GSK-J4 decreases expression ISO TMEM185B (Homo sapiens) 6480464 GSK-J4 results in decreased expression of TMEM185B mRNA CTD PMID:29301935 Tmem185b Rat hydrogen peroxide affects expression ISO TMEM185B (Homo sapiens) 6480464 Hydrogen Peroxide affects the expression of TMEM185B mRNA CTD PMID:20044591 Tmem185b Rat hydroxyurea decreases expression ISO TMEM185B (Homo sapiens) 6480464 Hydroxyurea results in decreased expression of TMEM185B mRNA CTD PMID:24211769 Tmem185b Rat inulin multiple interactions ISO Tmem185b (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of TMEM185B mRNA CTD PMID:36331819 Tmem185b Rat ketoconazole increases expression EXP 6480464 Ketoconazole results in increased expression of TMEM185B mRNA CTD PMID:36653537 Tmem185b Rat methyl methanesulfonate increases expression ISO TMEM185B (Homo sapiens) 6480464 Methyl Methanesulfonate results in increased expression of TMEM185B mRNA CTD PMID:23649840 Tmem185b Rat methyl methanesulfonate decreases expression ISO TMEM185B (Homo sapiens) 6480464 Methyl Methanesulfonate results in decreased expression of TMEM185B mRNA CTD PMID:24211769 Tmem185b Rat methylphenidate decreases expression ISO Tmem185b (Mus musculus) 6480464 Methylphenidate results in decreased expression of TMEM185B mRNA CTD PMID:22470460 Tmem185b Rat mitomycin C decreases expression ISO TMEM185B (Homo sapiens) 6480464 Mitomycin results in decreased expression of TMEM185B mRNA CTD PMID:24211769 Tmem185b Rat nickel atom increases expression ISO TMEM185B (Homo sapiens) 6480464 Nickel results in increased expression of TMEM185B mRNA CTD PMID:24768652|PMID:25583101 Tmem185b Rat paracetamol increases expression ISO TMEM185B (Homo sapiens) 6480464 Acetaminophen results in increased expression of TMEM185B mRNA CTD PMID:22230336 Tmem185b Rat paraquat increases expression EXP 6480464 Paraquat results in increased expression of TMEM185B mRNA CTD PMID:32680482 Tmem185b Rat perfluorooctane-1-sulfonic acid multiple interactions ISO Tmem185b (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of TMEM185B mRNA CTD PMID:36331819 Tmem185b Rat phenylmercury acetate decreases expression ISO TMEM185B (Homo sapiens) 6480464 Phenylmercuric Acetate results in decreased expression of TMEM185B mRNA CTD PMID:26272509 Tmem185b Rat phenylmercury acetate multiple interactions ISO TMEM185B (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... CTD PMID:27188386 Tmem185b Rat SB 431542 multiple interactions ISO TMEM185B (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... CTD PMID:27188386 Tmem185b Rat tetrachloromethane increases expression ISO Tmem185b (Mus musculus) 6480464 Carbon Tetrachloride results in increased expression of TMEM185B mRNA CTD PMID:27339419|PMID:31919559 Tmem185b Rat tetrachloromethane multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of TMEM185B mRNA] CTD PMID:31150632 Tmem185b Rat tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of TMEM185B mRNA CTD PMID:31150632 Tmem185b Rat thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of TMEM185B mRNA CTD PMID:34492290 Tmem185b Rat thiram decreases expression ISO TMEM185B (Homo sapiens) 6480464 Thiram results in decreased expression of TMEM185B mRNA CTD PMID:38568856 Tmem185b Rat titanium dioxide decreases expression ISO Tmem185b (Mus musculus) 6480464 titanium dioxide results in decreased expression of TMEM185B mRNA CTD PMID:29264374 Tmem185b Rat titanium dioxide decreases methylation ISO Tmem185b (Mus musculus) 6480464 titanium dioxide results in decreased methylation of TMEM185B promoter CTD PMID:35295148 Tmem185b Rat trichostatin A affects expression ISO TMEM185B (Homo sapiens) 6480464 trichostatin A affects the expression of TMEM185B mRNA CTD PMID:28542535 Tmem185b Rat urethane decreases expression ISO TMEM185B (Homo sapiens) 6480464 Urethane results in decreased expression of TMEM185B mRNA CTD PMID:28818685 Tmem185b Rat valproic acid increases methylation ISO TMEM185B (Homo sapiens) 6480464 Valproic Acid results in increased methylation of TMEM185B gene CTD PMID:29154799 Tmem185b Rat valproic acid decreases expression ISO TMEM185B (Homo sapiens) 6480464 Valproic Acid results in decreased expression of TMEM185B mRNA CTD PMID:26272509 Tmem185b Rat valproic acid affects expression ISO TMEM185B (Homo sapiens) 6480464 Valproic Acid affects the expression of TMEM185B mRNA CTD PMID:25979313 Tmem185b Rat vinclozolin increases expression EXP 6480464 vinclozolin results in increased expression of TMEM185B mRNA CTD PMID:23034163
References
Genomics
Comparative Map Data
Tmem185b (Rattus norvegicus - Norway rat)
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 13 33,200,329 - 33,203,660 (+) NCBI GRCr8 GRCr8 GRCr8 GRCr8 Ensembl 13 33,198,929 - 33,204,091 (+) Ensembl GRCr8 mRatBN7.2 13 30,647,533 - 30,650,864 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 13 30,647,482 - 30,650,858 (+) Ensembl mRatBN7.2 UTH_Rnor_SHR_Utx 13 33,228,893 - 33,232,226 (+) NCBI UTH_Rnor_SHR_Utx UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 13 34,516,732 - 34,520,065 (+) NCBI UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 13 31,790,854 - 31,794,186 (+) NCBI UTH_Rnor_WKY_Bbb_1.0 UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 13 35,554,621 - 35,557,952 (+) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 13 35,554,964 - 35,556,016 (+) Ensembl rn6 Rnor6.0 Rnor_5.0 13 40,669,220 - 40,672,564 (+) NCBI Rnor_5.0 Rnor_5.0 rn5 RGSC_v3.4 13 32,276,974 - 32,279,005 (+) NCBI RGSC_v3.4 RGSC_v3.4 rn4 Celera 13 30,543,175 - 30,546,506 (+) NCBI Celera RGSC_v3.1 13 32,280,108 - 32,281,829 (+) NCBI Cytogenetic Map 13 q11 NCBI
TMEM185B (Homo sapiens - human)
Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 2 120,217,479 - 120,223,400 (-) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 2 120,217,479 - 120,223,400 (-) Ensembl hg38 GRCh38 GRCh37 2 120,975,055 - 120,980,976 (-) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 2 120,695,324 - 120,697,454 (-) NCBI Build 36 Build 36 hg18 NCBI36 Celera 2 114,305,701 - 114,307,831 (-) NCBI Celera Cytogenetic Map 2 q14.2 NCBI HuRef 2 113,298,822 - 113,304,759 (-) NCBI HuRef CHM1_1 2 120,979,441 - 120,985,378 (-) NCBI CHM1_1 T2T-CHM13v2.0 2 120,652,239 - 120,658,160 (-) NCBI T2T-CHM13v2.0
Tmem185b (Mus musculus - house mouse)
Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 1 119,453,884 - 119,456,713 (+) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 1 119,453,890 - 119,456,713 (+) Ensembl GRCm39 Ensembl GRCm39 GRCm38 1 119,526,154 - 119,528,983 (+) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 1 119,526,160 - 119,528,983 (+) Ensembl mm10 GRCm38 MGSCv37 1 121,422,744 - 121,424,803 (+) NCBI MGSCv37 MGSCv37 mm9 NCBIm37 MGSCv36 1 121,353,713 - 121,355,772 (+) NCBI MGSCv36 mm8 Celera 1 122,184,964 - 122,187,094 (+) NCBI Celera Cytogenetic Map 1 E2.3 NCBI cM Map 1 52.31 NCBI
Tmem185b (Chinchilla lanigera - long-tailed chinchilla)
Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 NW_004955459 9,610,905 - 9,613,405 (+) NCBI ChiLan1.0 ChiLan1.0
TMEM185B (Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 13 22,219,290 - 22,225,355 (-) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 2B 22,238,267 - 22,240,349 (-) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 2B 7,149,925 - 7,155,857 (-) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 2B 120,725,913 - 120,731,687 (-) NCBI PanPan1.1 PanPan1.1 panPan2
TMEM185B (Canis lupus familiaris - dog)
Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 19 29,892,735 - 29,894,526 (+) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 19 30,149,219 - 30,151,009 (+) NCBI Dog10K_Boxer_Tasha Dog10K_Boxer_Tasha ROS_Cfam_1.0 19 31,268,313 - 31,270,107 (+) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl 19 31,268,280 - 31,270,103 (+) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 19 29,954,584 - 29,956,373 (+) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 19 30,123,872 - 30,125,662 (+) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 19 31,309,974 - 31,311,768 (+) NCBI UU_Cfam_GSD_1.0 UU_Cfam_GSD_1.0
Tmem185b (Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl HiC_Itri_2 NW_024405303 91,308,751 - 91,314,210 (-) NCBI HiC_Itri_2 SpeTri2.0 Ensembl NW_004936469 50,303,976 - 50,305,028 (+) Ensembl SpeTri2.0 Ensembl SpeTri2.0 NW_004936469 50,303,513 - 50,306,321 (+) NCBI SpeTri2.0 SpeTri2.0 SpeTri2.0
TMEM185B (Sus scrofa - pig)
Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl 15 31,141,126 - 31,142,181 (+) Ensembl susScr11 Sscrofa11.1 Sscrofa11.1 15 31,140,283 - 31,146,656 (+) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 15 36,617,474 - 36,619,775 (-) NCBI Sscrofa10.2 Sscrofa10.2 susScr3
TMEM185B (Chlorocebus sabaeus - green monkey)
Green Monkey Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChlSab1.1 10 10,068,817 - 10,070,996 (+) NCBI ChlSab1.1 ChlSab1.1 chlSab2 ChlSab1.1 Ensembl 10 10,069,244 - 10,070,296 (+) Ensembl ChlSab1.1 Ensembl chlSab2 Vervet-AGM Vero_WHO_p1.0 NW_023666061 12,616,649 - 12,619,722 (-) NCBI Vero_WHO_p1.0 Vero_WHO_p1.0
Tmem185b (Heterocephalus glaber - naked mole-rat)
Tmem185b (Rattus rattus - black rat)
miRNA Target Status (No longer updated)
Predicted Target Of
Count of predictions: 201 Count of miRNA genes: 155 Interacting mature miRNAs: 169 Transcripts: ENSRNOT00000072632 Prediction methods: Miranda Result types: miRGate_prediction