Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Nol8 | Rat | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of NOL8 mRNA] | CTD | PMID:31150632 | Nol8 | Rat | (-)-alpha-phellandrene | decreases expression | ISO | NOL8 (Homo sapiens) | 6480464 | alpha phellandrene results in decreased expression of NOL8 mRNA | CTD | PMID:25075043 | Nol8 | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Nol8 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of NOL8 mRNA | CTD | PMID:36331819 | Nol8 | Rat | 1,2-dimethylhydrazine | increases expression | ISO | Nol8 (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in increased expression of NOL8 mRNA | CTD | PMID:22206623 | Nol8 | Rat | 17alpha-ethynylestradiol | increases expression | ISO | Nol8 (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of NOL8 mRNA | CTD | PMID:17942748 | Nol8 | Rat | 17alpha-ethynylestradiol | multiple interactions | ISO | Nol8 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of NOL8 mRNA | CTD | PMID:17942748 | Nol8 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Nol8 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of NOL8 mRNA | CTD | PMID:17942748 | Nol8 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of NOL8 mRNA | CTD | PMID:33387578 | Nol8 | Rat | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2,4-dinitrotoluene affects the expression of NOL8 mRNA | CTD | PMID:21346803 | Nol8 | Rat | 2-methylcholine | affects expression | ISO | NOL8 (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of NOL8 mRNA | CTD | PMID:21179406 | Nol8 | Rat | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | NOL8 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] more ... | CTD | PMID:28628672 | Nol8 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | Nol8 (Mus musculus) | 6480464 | bisphenol S results in increased expression of NOL8 mRNA | CTD | PMID:39298647 | Nol8 | Rat | 4-amino-2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 4-amino-2,6-dinitrotoluene affects the expression of NOL8 mRNA | CTD | PMID:21346803 | Nol8 | Rat | 4-hydroxyphenyl retinamide | decreases expression | ISO | Nol8 (Mus musculus) | 6480464 | Fenretinide results in decreased expression of NOL8 mRNA | CTD | PMID:28973697 | Nol8 | Rat | acrolein | multiple interactions | ISO | NOL8 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of more ... | CTD | PMID:32699268 | Nol8 | Rat | aflatoxin B1 | increases expression | ISO | Nol8 (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of NOL8 mRNA | CTD | PMID:19770486 | Nol8 | Rat | all-trans-retinoic acid | increases expression | EXP | | 6480464 | Tretinoin results in increased expression of NOL8 mRNA | CTD | PMID:20488242 | Nol8 | Rat | alpha-phellandrene | decreases expression | ISO | NOL8 (Homo sapiens) | 6480464 | alpha phellandrene results in decreased expression of NOL8 mRNA | CTD | PMID:25075043 | Nol8 | Rat | alpha-pinene | multiple interactions | ISO | NOL8 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of more ... | CTD | PMID:32699268 | Nol8 | Rat | antirheumatic drug | decreases expression | ISO | NOL8 (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of NOL8 mRNA | CTD | PMID:24449571 | Nol8 | Rat | arsane | multiple interactions | ISO | NOL8 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Nol8 | Rat | arsenic atom | multiple interactions | ISO | NOL8 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Nol8 | Rat | beta-lapachone | decreases expression | ISO | NOL8 (Homo sapiens) | 6480464 | beta-lapachone results in decreased expression of NOL8 mRNA | CTD | PMID:38218311 | Nol8 | Rat | bis(2-ethylhexyl) phthalate | increases expression | ISO | Nol8 (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in increased expression of NOL8 mRNA | CTD | PMID:34319233 | Nol8 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of NOL8 mRNA | CTD | PMID:25181051|PMID:30816183|PMID:32528016|PMID:34947998 | Nol8 | Rat | bisphenol A | multiple interactions | ISO | NOL8 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] more ... | CTD | PMID:28628672 | Nol8 | Rat | bisphenol F | multiple interactions | ISO | NOL8 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] more ... | CTD | PMID:28628672 | Nol8 | Rat | bromobenzene | increases expression | EXP | | 6480464 | bromobenzene results in increased expression of NOL8 mRNA | CTD | PMID:32479839 | Nol8 | Rat | cadmium atom | multiple interactions | ISO | Nol8 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of NOL8 more ... | CTD | PMID:37236586 | Nol8 | Rat | cadmium dichloride | decreases methylation | EXP | | 6480464 | Cadmium Chloride results in decreased methylation of NOL8 promoter | CTD | PMID:22457795 | Nol8 | Rat | cadmium dichloride | multiple interactions | ISO | Nol8 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of NOL8 more ... | CTD | PMID:37236586 | Nol8 | Rat | cadmium dichloride | decreases expression | ISO | NOL8 (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of NOL8 mRNA | CTD | PMID:38568856 | Nol8 | Rat | cadmium dichloride | increases expression | ISO | NOL8 (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of NOL8 mRNA | CTD | PMID:26472689 | Nol8 | Rat | cadmium dichloride | decreases expression | ISO | Nol8 (Mus musculus) | 6480464 | Cadmium Chloride results in decreased expression of NOL8 mRNA | CTD | PMID:24982889 | Nol8 | Rat | caffeine | affects phosphorylation | ISO | NOL8 (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of NOL8 protein | CTD | PMID:35688186 | Nol8 | Rat | CGP 52608 | multiple interactions | ISO | NOL8 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to NOL8 gene] | CTD | PMID:28238834 | Nol8 | Rat | chlorpyrifos | decreases expression | ISO | Nol8 (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of NOL8 mRNA | CTD | PMID:37019170 | Nol8 | Rat | chromium(6+) | affects expression | ISO | Nol8 (Mus musculus) | 6480464 | chromium hexavalent ion affects the expression of NOL8 mRNA | CTD | PMID:28472532 | Nol8 | Rat | cisplatin | multiple interactions | ISO | NOL8 (Homo sapiens) | 6480464 | [Piroxicam co-treated with Cisplatin] results in decreased expression of NOL8 mRNA | CTD | PMID:21858171 | Nol8 | Rat | clofibric acid | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of NOL8 mRNA | CTD | PMID:17602206 | Nol8 | Rat | coumarin | increases expression | EXP | | 6480464 | coumarin results in increased expression of NOL8 mRNA | CTD | PMID:18480146 | Nol8 | Rat | coumarin | decreases phosphorylation | ISO | NOL8 (Homo sapiens) | 6480464 | coumarin results in decreased phosphorylation of NOL8 protein | CTD | PMID:35688186 | Nol8 | Rat | cyclosporin A | increases expression | ISO | NOL8 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of NOL8 mRNA | CTD | PMID:20106945|PMID:25562108|PMID:27989131 | Nol8 | Rat | DDE | increases expression | ISO | NOL8 (Homo sapiens) | 6480464 | Dichlorodiphenyl Dichloroethylene results in increased expression of NOL8 mRNA | CTD | PMID:38568856 | Nol8 | Rat | dexamethasone | multiple interactions | ISO | NOL8 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] more ... | CTD | PMID:28628672 | Nol8 | Rat | dibutyl phthalate | increases expression | EXP | | 6480464 | Dibutyl Phthalate results in increased expression of NOL8 mRNA | CTD | PMID:21266533 | Nol8 | Rat | dicrotophos | decreases expression | ISO | NOL8 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of NOL8 mRNA | CTD | PMID:28302478 | Nol8 | Rat | diethylstilbestrol | decreases expression | ISO | NOL8 (Homo sapiens) | 6480464 | Diethylstilbestrol results in decreased expression of NOL8 mRNA | CTD | PMID:36621641 | Nol8 | Rat | doxorubicin | decreases expression | ISO | NOL8 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of NOL8 mRNA | CTD | PMID:29803840 | Nol8 | Rat | elemental selenium | multiple interactions | ISO | NOL8 (Homo sapiens) | 6480464 | [Selenium co-treated with Vitamin E] results in decreased expression of NOL8 mRNA | CTD | PMID:19244175 | Nol8 | Rat | elemental selenium | decreases expression | ISO | NOL8 (Homo sapiens) | 6480464 | Selenium results in decreased expression of NOL8 mRNA | CTD | PMID:19244175 | Nol8 | Rat | enzyme inhibitor | multiple interactions | ISO | NOL8 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation more ... | CTD | PMID:23301498 | Nol8 | Rat | fluoranthene | multiple interactions | ISO | Nol8 (Mus musculus) | 6480464 | [1-methylanthracene co-treated with fluoranthene] results in increased expression of NOL8 mRNA | CTD | PMID:28329830 | Nol8 | Rat | FR900359 | affects phosphorylation | ISO | NOL8 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of NOL8 protein | CTD | PMID:37730182 | Nol8 | Rat | furan | increases expression | EXP | | 6480464 | furan results in increased expression of NOL8 mRNA | CTD | PMID:26194646 | Nol8 | Rat | hexadecanoic acid | increases phosphorylation | ISO | NOL8 (Homo sapiens) | 6480464 | Palmitic Acid results in increased phosphorylation of NOL8 protein | CTD | PMID:28073184 | Nol8 | Rat | hydrogen peroxide | affects expression | ISO | NOL8 (Homo sapiens) | 6480464 | Hydrogen Peroxide affects the expression of NOL8 mRNA | CTD | PMID:20044591|PMID:21179406 | Nol8 | Rat | indometacin | multiple interactions | ISO | NOL8 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] more ... | CTD | PMID:28628672 | Nol8 | Rat | manganese atom | multiple interactions | ISO | NOL8 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Nol8 | Rat | manganese(0) | multiple interactions | ISO | NOL8 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Nol8 | Rat | manganese(II) chloride | multiple interactions | ISO | NOL8 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Nol8 | Rat | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of NOL8 mRNA | CTD | PMID:17602206 | Nol8 | Rat | ozone | multiple interactions | ISO | NOL8 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of more ... | CTD | PMID:32699268 | Nol8 | Rat | ozone | multiple interactions | ISO | Nol8 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which results in increased expression of NOL8 more ... | CTD | PMID:27106289 | Nol8 | Rat | paracetamol | decreases expression | ISO | NOL8 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of NOL8 mRNA | CTD | PMID:21420995 | Nol8 | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of NOL8 mRNA | CTD | PMID:33387578 | Nol8 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Nol8 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of NOL8 mRNA | CTD | PMID:36331819 | Nol8 | Rat | phenobarbital | affects expression | ISO | NOL8 (Homo sapiens) | 6480464 | Phenobarbital affects the expression of NOL8 mRNA | CTD | PMID:19159669 | Nol8 | Rat | phenobarbital | affects expression | ISO | Nol8 (Mus musculus) | 6480464 | Phenobarbital affects the expression of NOL8 mRNA | CTD | PMID:23091169 | Nol8 | Rat | piroxicam | multiple interactions | ISO | NOL8 (Homo sapiens) | 6480464 | [Piroxicam co-treated with Cisplatin] results in decreased expression of NOL8 mRNA | CTD | PMID:21858171 | Nol8 | Rat | propiconazole | increases expression | ISO | Nol8 (Mus musculus) | 6480464 | propiconazole results in increased expression of NOL8 mRNA | CTD | PMID:21278054 | Nol8 | Rat | Salinomycin | decreases expression | ISO | NOL8 (Homo sapiens) | 6480464 | salinomycin results in decreased expression of NOL8 mRNA | CTD | PMID:19682730 | Nol8 | Rat | selenium atom | multiple interactions | ISO | NOL8 (Homo sapiens) | 6480464 | [Selenium co-treated with Vitamin E] results in decreased expression of NOL8 mRNA | CTD | PMID:19244175 | Nol8 | Rat | selenium atom | decreases expression | ISO | NOL8 (Homo sapiens) | 6480464 | Selenium results in decreased expression of NOL8 mRNA | CTD | PMID:19244175 | Nol8 | Rat | silicon dioxide | increases expression | ISO | Nol8 (Mus musculus) | 6480464 | Silicon Dioxide results in increased expression of NOL8 mRNA | CTD | PMID:23221170 | Nol8 | Rat | sodium arsenite | decreases expression | ISO | NOL8 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of NOL8 mRNA | CTD | PMID:38568856 | Nol8 | Rat | sodium arsenite | multiple interactions | ISO | NOL8 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Nol8 | Rat | sodium dichromate | increases expression | EXP | | 6480464 | sodium bichromate results in increased expression of NOL8 mRNA | CTD | PMID:25993096 | Nol8 | Rat | tacrolimus hydrate | increases expression | ISO | Nol8 (Mus musculus) | 6480464 | Tacrolimus results in increased expression of NOL8 mRNA | CTD | PMID:25270620 | Nol8 | Rat | tetrachloromethane | increases expression | ISO | Nol8 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of NOL8 mRNA | CTD | PMID:27339419|PMID:31919559 | Nol8 | Rat | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of NOL8 mRNA | CTD | PMID:30723492|PMID:31150632 | Nol8 | Rat | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of NOL8 mRNA] | CTD | PMID:31150632 | Nol8 | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of NOL8 mRNA | CTD | PMID:23411599|PMID:34492290 | Nol8 | Rat | triphenyl phosphate | decreases expression | EXP | | 6480464 | triphenyl phosphate results in decreased expression of NOL8 mRNA | CTD | PMID:30589522 | Nol8 | Rat | triphenyl phosphate | affects expression | ISO | NOL8 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of NOL8 mRNA | CTD | PMID:37042841 | Nol8 | Rat | troglitazone | decreases expression | ISO | Nol8 (Mus musculus) | 6480464 | troglitazone results in decreased expression of NOL8 mRNA | CTD | PMID:28973697 | Nol8 | Rat | valproic acid | affects expression | ISO | NOL8 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of NOL8 mRNA | CTD | PMID:25979313 | Nol8 | Rat | vitamin E | multiple interactions | ISO | NOL8 (Homo sapiens) | 6480464 | [Selenium co-treated with Vitamin E] results in decreased expression of NOL8 mRNA | CTD | PMID:19244175 | Nol8 | Rat | vitamin E | decreases expression | ISO | NOL8 (Homo sapiens) | 6480464 | Vitamin E results in decreased expression of NOL8 mRNA | CTD | PMID:19244175 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















