Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Ppp1r18 | Rat | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | PPP1R18 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of PPP1R18 mRNA | CTD | PMID:22079256 | Ppp1r18 | Rat | 1,2-dimethylhydrazine | increases expression | ISO | Ppp1r18 (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in increased expression of PPP1R18 mRNA | CTD | PMID:22206623 | Ppp1r18 | Rat | 17beta-estradiol | multiple interactions | ISO | PPP1R18 (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in increased expression of PPP1R18 mRNA | CTD | PMID:30165855 | Ppp1r18 | Rat | 17beta-estradiol | decreases expression | ISO | Ppp1r18 (Mus musculus) | 6480464 | Estradiol results in decreased expression of PPP1R18 mRNA | CTD | PMID:39298647 | Ppp1r18 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of PPP1R18 mRNA | CTD | PMID:34747641 | Ppp1r18 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of PPP1R18 mRNA | CTD | PMID:33387578 | Ppp1r18 | Rat | 2-hydroxypropanoic acid | increases expression | ISO | PPP1R18 (Homo sapiens) | 6480464 | Lactic Acid results in increased expression of PPP1R18 mRNA | CTD | PMID:30851411 | Ppp1r18 | Rat | 2-palmitoylglycerol | increases expression | ISO | PPP1R18 (Homo sapiens) | 6480464 | 2-palmitoylglycerol results in increased expression of PPP1R18 mRNA | CTD | PMID:37199045 | Ppp1r18 | Rat | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | PPP1R18 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] more ... | CTD | PMID:28628672 | Ppp1r18 | Rat | 4,4'-diaminodiphenylmethane | increases expression | EXP | | 6480464 | 4,4'-diaminodiphenylmethane results in increased expression of PPP1R18 mRNA | CTD | PMID:25380136 | Ppp1r18 | Rat | 4,4'-sulfonyldiphenol | affects methylation | ISO | Ppp1r18 (Mus musculus) | 6480464 | bisphenol S affects the methylation of PPP1R18 gene | CTD | PMID:31683443 | Ppp1r18 | Rat | 5-aza-2'-deoxycytidine | affects expression | ISO | PPP1R18 (Homo sapiens) | 6480464 | Decitabine affects the expression of PPP1R18 mRNA | CTD | PMID:23300844 | Ppp1r18 | Rat | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of PPP1R18 mRNA | CTD | PMID:24780913 | Ppp1r18 | Rat | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of PPP1R18 mRNA | CTD | PMID:31881176 | Ppp1r18 | Rat | acrylamide | increases expression | ISO | PPP1R18 (Homo sapiens) | 6480464 | Acrylamide results in increased expression of PPP1R18 mRNA | CTD | PMID:32763439 | Ppp1r18 | Rat | aflatoxin B1 | affects expression | ISO | PPP1R18 (Homo sapiens) | 6480464 | Aflatoxin B1 affects the expression of PPP1R18 protein | CTD | PMID:20106945 | Ppp1r18 | Rat | aflatoxin B1 | increases expression | ISO | PPP1R18 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of PPP1R18 mRNA | CTD | PMID:27153756 | Ppp1r18 | Rat | all-trans-retinoic acid | increases expression | ISO | PPP1R18 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of PPP1R18 mRNA | CTD | PMID:23724009|PMID:33167477 | Ppp1r18 | Rat | alpha-Zearalanol | increases expression | EXP | | 6480464 | Zeranol results in increased expression of PPP1R18 mRNA | CTD | PMID:35163327 | Ppp1r18 | Rat | arsane | multiple interactions | ISO | PPP1R18 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Ppp1r18 | Rat | arsenic atom | multiple interactions | ISO | PPP1R18 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Ppp1r18 | Rat | avobenzone | increases expression | ISO | PPP1R18 (Homo sapiens) | 6480464 | avobenzone results in increased expression of PPP1R18 mRNA | CTD | PMID:31016361 | Ppp1r18 | Rat | azathioprine | increases expression | ISO | PPP1R18 (Homo sapiens) | 6480464 | Azathioprine results in increased expression of PPP1R18 mRNA | CTD | PMID:22623647 | Ppp1r18 | Rat | benzo[a]pyrene | increases expression | ISO | PPP1R18 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of PPP1R18 mRNA | CTD | PMID:26238291|PMID:32234424 | Ppp1r18 | Rat | benzo[a]pyrene | decreases methylation | ISO | Ppp1r18 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased methylation of PPP1R18 promoter | CTD | PMID:27901495 | Ppp1r18 | Rat | benzo[a]pyrene | increases methylation | ISO | PPP1R18 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of PPP1R18 3' UTR; Benzo(a)pyrene results in increased methylation of more ... | CTD | PMID:27901495 | Ppp1r18 | Rat | beta-lapachone | increases expression | ISO | PPP1R18 (Homo sapiens) | 6480464 | beta-lapachone results in increased expression of PPP1R18 mRNA | CTD | PMID:38218311 | Ppp1r18 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of PPP1R18 mRNA | CTD | PMID:25181051 | Ppp1r18 | Rat | bisphenol A | decreases expression | ISO | PPP1R18 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of PPP1R18 mRNA; bisphenol A results in decreased expression more ... | CTD | PMID:29275510|PMID:34186270 | Ppp1r18 | Rat | bisphenol AF | increases expression | ISO | PPP1R18 (Homo sapiens) | 6480464 | bisphenol AF results in increased expression of PPP1R18 protein | CTD | PMID:34186270 | Ppp1r18 | Rat | Bisphenol B | increases expression | ISO | PPP1R18 (Homo sapiens) | 6480464 | bisphenol B results in increased expression of PPP1R18 protein | CTD | PMID:34186270 | Ppp1r18 | Rat | bisphenol F | multiple interactions | ISO | PPP1R18 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] more ... | CTD | PMID:28628672 | Ppp1r18 | Rat | bisphenol F | increases expression | ISO | PPP1R18 (Homo sapiens) | 6480464 | bisphenol F results in increased expression of PPP1R18 protein | CTD | PMID:34186270 | Ppp1r18 | Rat | cadmium atom | multiple interactions | EXP | | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PPP1R18 more ... | CTD | PMID:39012411 | Ppp1r18 | Rat | cadmium atom | multiple interactions | ISO | Ppp1r18 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PPP1R18 more ... | CTD | PMID:37236586 | Ppp1r18 | Rat | cadmium dichloride | decreases expression | EXP | | 6480464 | Cadmium Chloride results in decreased expression of PPP1R18 mRNA | CTD | PMID:33453195 | Ppp1r18 | Rat | cadmium dichloride | multiple interactions | EXP | | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PPP1R18 more ... | CTD | PMID:39012411 | Ppp1r18 | Rat | cadmium dichloride | multiple interactions | ISO | Ppp1r18 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PPP1R18 more ... | CTD | PMID:37236586 | Ppp1r18 | Rat | cadmium dichloride | increases expression | ISO | PPP1R18 (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of PPP1R18 mRNA | CTD | PMID:38568856 | Ppp1r18 | Rat | caffeine | decreases phosphorylation | ISO | PPP1R18 (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of PPP1R18 protein | CTD | PMID:35688186 | Ppp1r18 | Rat | carbon nanotube | increases expression | ISO | Ppp1r18 (Mus musculus) | 6480464 | Nanotubes, Carbon analog results in increased expression of PPP1R18 mRNA | CTD | PMID:25554681 | Ppp1r18 | Rat | chlorpyrifos | increases expression | ISO | Ppp1r18 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of PPP1R18 mRNA | CTD | PMID:37019170 | Ppp1r18 | Rat | cisplatin | decreases expression | EXP | | 6480464 | Cisplatin results in decreased expression of PPP1R18 mRNA | CTD | PMID:22023808 | Ppp1r18 | Rat | cisplatin | affects expression | ISO | PPP1R18 (Homo sapiens) | 6480464 | Cisplatin affects the expression of PPP1R18 mRNA | CTD | PMID:23300844 | Ppp1r18 | Rat | copper atom | multiple interactions | ISO | PPP1R18 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in increased expression of PPP1R18 mRNA | CTD | PMID:20971185 | Ppp1r18 | Rat | copper(0) | multiple interactions | ISO | PPP1R18 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in increased expression of PPP1R18 mRNA | CTD | PMID:20971185 | Ppp1r18 | Rat | copper(II) chloride | increases expression | ISO | PPP1R18 (Homo sapiens) | 6480464 | cupric chloride results in increased expression of PPP1R18 mRNA | CTD | PMID:38568856 | Ppp1r18 | Rat | Cuprizon | increases expression | EXP | | 6480464 | Cuprizone results in increased expression of PPP1R18 mRNA | CTD | PMID:26577399 | Ppp1r18 | Rat | cyclosporin A | increases expression | ISO | PPP1R18 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of PPP1R18 mRNA | CTD | PMID:20106945|PMID:21632981|PMID:25562108 | Ppp1r18 | Rat | cyclosporin A | decreases expression | ISO | PPP1R18 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of PPP1R18 mRNA | CTD | PMID:27989131 | Ppp1r18 | Rat | dexamethasone | multiple interactions | ISO | PPP1R18 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] more ... | CTD | PMID:28628672 | Ppp1r18 | Rat | doxorubicin | affects expression | ISO | PPP1R18 (Homo sapiens) | 6480464 | Doxorubicin affects the expression of PPP1R18 mRNA | CTD | PMID:29803840 | Ppp1r18 | Rat | FR900359 | affects phosphorylation | ISO | PPP1R18 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of PPP1R18 protein | CTD | PMID:37730182 | Ppp1r18 | Rat | fulvestrant | decreases methylation | ISO | PPP1R18 (Homo sapiens) | 6480464 | Fulvestrant results in decreased methylation of PPP1R18 gene | CTD | PMID:31601247 | Ppp1r18 | Rat | gallic acid | increases expression | ISO | PPP1R18 (Homo sapiens) | 6480464 | Gallic Acid results in increased expression of PPP1R18 mRNA | CTD | PMID:34408198 | Ppp1r18 | Rat | hydrogen peroxide | multiple interactions | ISO | Ppp1r18 (Mus musculus) | 6480464 | [Hydrogen Peroxide co-treated with N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride] results in increased phosphorylation of PPP1R18 protein | CTD | PMID:31494107 | Ppp1r18 | Rat | indometacin | multiple interactions | ISO | PPP1R18 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] more ... | CTD | PMID:28628672 | Ppp1r18 | Rat | iron dichloride | increases expression | ISO | PPP1R18 (Homo sapiens) | 6480464 | ferrous chloride results in increased expression of PPP1R18 mRNA | CTD | PMID:35984750 | Ppp1r18 | Rat | ivermectin | decreases expression | ISO | PPP1R18 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of PPP1R18 protein | CTD | PMID:32959892 | Ppp1r18 | Rat | ketamine | decreases expression | EXP | | 6480464 | Ketamine results in decreased expression of PPP1R18 mRNA | CTD | PMID:20080153 | Ppp1r18 | Rat | lead diacetate | increases expression | ISO | PPP1R18 (Homo sapiens) | 6480464 | lead acetate results in increased expression of PPP1R18 mRNA | CTD | PMID:38568856 | Ppp1r18 | Rat | manganese atom | multiple interactions | ISO | PPP1R18 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Ppp1r18 | Rat | manganese(0) | multiple interactions | ISO | PPP1R18 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Ppp1r18 | Rat | manganese(II) chloride | multiple interactions | ISO | PPP1R18 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Ppp1r18 | Rat | methidathion | increases expression | ISO | Ppp1r18 (Mus musculus) | 6480464 | methidathion results in increased expression of PPP1R18 mRNA | CTD | PMID:34813904 | Ppp1r18 | Rat | mono(2-ethylhexyl) phthalate | affects expression | ISO | Ppp1r18 (Mus musculus) | 6480464 | mono-(2-ethylhexyl)phthalate affects the expression of PPP1R18 mRNA | CTD | PMID:21195148 | Ppp1r18 | Rat | Monobutylphthalate | affects expression | ISO | Ppp1r18 (Mus musculus) | 6480464 | monobutyl phthalate affects the expression of PPP1R18 mRNA | CTD | PMID:21195148 | Ppp1r18 | Rat | N-nitrosodimethylamine | increases expression | EXP | | 6480464 | Dimethylnitrosamine results in increased expression of PPP1R18 mRNA | CTD | PMID:25380136 | Ppp1r18 | Rat | nickel atom | increases expression | ISO | PPP1R18 (Homo sapiens) | 6480464 | Nickel results in increased expression of PPP1R18 mRNA | CTD | PMID:24768652|PMID:25583101 | Ppp1r18 | Rat | nitrates | multiple interactions | ISO | Ppp1r18 (Mus musculus) | 6480464 | [Particulate Matter results in increased abundance of Nitrates] which results in increased expression of PPP1R18 more ... | CTD | PMID:35964746 | Ppp1r18 | Rat | okadaic acid | increases expression | ISO | PPP1R18 (Homo sapiens) | 6480464 | Okadaic Acid results in increased expression of PPP1R18 mRNA | CTD | PMID:38832940 | Ppp1r18 | Rat | paracetamol | decreases expression | ISO | PPP1R18 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of PPP1R18 mRNA | CTD | PMID:21420995 | Ppp1r18 | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of PPP1R18 mRNA | CTD | PMID:33387578 | Ppp1r18 | Rat | paracetamol | increases expression | ISO | PPP1R18 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of PPP1R18 mRNA | CTD | PMID:22230336 | Ppp1r18 | Rat | pentachlorophenol | increases expression | ISO | Ppp1r18 (Mus musculus) | 6480464 | Pentachlorophenol results in increased expression of PPP1R18 mRNA | CTD | PMID:23892564 | Ppp1r18 | Rat | potassium chromate | multiple interactions | ISO | PPP1R18 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of PPP1R18 mRNA | CTD | PMID:22079256 | Ppp1r18 | Rat | potassium chromate | increases expression | ISO | PPP1R18 (Homo sapiens) | 6480464 | potassium chromate(VI) results in increased expression of PPP1R18 mRNA | CTD | PMID:22079256 | Ppp1r18 | Rat | quercetin | increases expression | ISO | PPP1R18 (Homo sapiens) | 6480464 | Quercetin results in increased expression of PPP1R18 mRNA | CTD | PMID:21632981 | Ppp1r18 | Rat | rac-lactic acid | increases expression | ISO | PPP1R18 (Homo sapiens) | 6480464 | Lactic Acid results in increased expression of PPP1R18 mRNA | CTD | PMID:30851411 | Ppp1r18 | Rat | resveratrol | multiple interactions | ISO | PPP1R18 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of PPP1R18 mRNA | CTD | PMID:23557933 | Ppp1r18 | Rat | sodium arsenite | increases expression | ISO | PPP1R18 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of PPP1R18 mRNA | CTD | PMID:29301061|PMID:38568856 | Ppp1r18 | Rat | sodium arsenite | multiple interactions | ISO | PPP1R18 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Ppp1r18 | Rat | Soman | increases expression | EXP | | 6480464 | Soman results in increased expression of PPP1R18 mRNA | CTD | PMID:19281266 | Ppp1r18 | Rat | sunitinib | decreases expression | ISO | PPP1R18 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of PPP1R18 mRNA | CTD | PMID:31533062 | Ppp1r18 | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of PPP1R18 mRNA | CTD | PMID:34492290 | Ppp1r18 | Rat | thiram | increases expression | ISO | PPP1R18 (Homo sapiens) | 6480464 | Thiram results in increased expression of PPP1R18 mRNA | CTD | PMID:38568856 | Ppp1r18 | Rat | triclosan | increases methylation | ISO | PPP1R18 (Homo sapiens) | 6480464 | Triclosan results in increased methylation of PPP1R18 gene | CTD | PMID:34523531 | Ppp1r18 | Rat | triphenyl phosphate | affects expression | ISO | PPP1R18 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of PPP1R18 mRNA | CTD | PMID:37042841 | Ppp1r18 | Rat | triptonide | increases expression | ISO | Ppp1r18 (Mus musculus) | 6480464 | triptonide results in increased expression of PPP1R18 mRNA | CTD | PMID:33045310 | Ppp1r18 | Rat | tris(2-butoxyethyl) phosphate | affects expression | ISO | PPP1R18 (Homo sapiens) | 6480464 | tris(2-butoxyethyl) phosphate affects the expression of PPP1R18 mRNA | CTD | PMID:29024780 | Ppp1r18 | Rat | vinclozolin | affects expression | EXP | | 6480464 | vinclozolin affects the expression of PPP1R18 mRNA | CTD | PMID:19015723 | Ppp1r18 | Rat | zinc atom | multiple interactions | ISO | PPP1R18 (Homo sapiens) | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of PPP1R18 mRNA | CTD | PMID:18593933 | Ppp1r18 | Rat | zinc(0) | multiple interactions | ISO | PPP1R18 (Homo sapiens) | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of PPP1R18 mRNA | CTD | PMID:18593933 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















