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Gene: Bora (bora, aurora kinase A activator) Rattus norvegicus

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Symbol:

Bora

Name:

bora, aurora kinase A activator

RGD ID:

1309522

Description:

Predicted to enable protein kinase binding activity. Predicted to be involved in regulation of mitotic nuclear division; regulation of mitotic spindle organization; and regulation of protein localization. Predicted to be located in meiotic spindle. Predicted to be active in cytoplasm and nucleus. Orthologous to human BORA (BORA aurora kinase A activator); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; acetamide.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

aurora borealis; LOC306102; RGD1309522; similar to hypothetical protein FLJ22624

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	BORA (BORA aurora kinase A activator)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Bora (bora, aurora kinase A activator)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Bora (BORA aurora kinase A activator)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	BORA (BORA aurora kinase A activator)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	BORA (BORA aurora kinase A activator)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Bora (BORA aurora kinase A activator)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	BORA (BORA aurora kinase A activator)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	BORA (BORA aurora kinase A activator)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Bora (BORA aurora kinase A activator)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Bora (BORA aurora kinase A activator)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Bora (bora, aurora kinase A activator)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	BORA (BORA aurora kinase A activator)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	bora (bora aurora kinase A activator)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	bora	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|OrthoInspector\|PANTHER)
Drosophila melanogaster (fruit fly):	bora	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	spat-1	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	bora	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	82,205,467 - 82,243,499 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	15	82,205,697 - 82,244,052 (+)	Ensembl				GRCr8
mRatBN7.2	15	75,797,624 - 75,835,599 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	75,797,891 - 75,821,322 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	15	79,780,918 - 79,805,541 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	15	80,857,536 - 80,882,159 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	15	77,805,079 - 77,829,702 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	15	83,442,217 - 83,463,737 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	83,442,144 - 83,463,717 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	15	86,953,333 - 86,975,601 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	15	82,829,209 - 82,852,061 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	15	75,035,699 - 75,061,119 (+)	NCBI		Celera
RGSC_v3.1	15	82,844,988 - 82,867,842 (+)	NCBI
Cytogenetic Map	15	q21	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

(1->4)-beta-D-glucan (ISO)

1,1-dichloroethene (ISO)

1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2,4,4'-trichlorobiphenyl (ISO)

3,3',4,4',5-pentachlorobiphenyl (EXP)

5-aza-2'-deoxycytidine (ISO)

5-fluorouracil (ISO)

acetamide (EXP)

acrolein (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

alpha-pinene (ISO)

amphotericin B (ISO)

arsane (ISO)

arsenic atom (ISO)

azathioprine (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bis(2-chloroethyl) sulfide (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

Butylbenzyl phthalate (ISO)

cadmium dichloride (EXP)

caffeine (ISO)

cannabidiol (ISO)

chlorpyrifos (ISO)

chromium(6+) (ISO)

cisplatin (ISO)

clobetasol (ISO)

copper(II) sulfate (ISO)

coumestrol (ISO)

cyclosporin A (ISO)

cytarabine (ISO)

dicrotophos (ISO)

epoxiconazole (ISO)

formaldehyde (ISO)

gentamycin (EXP)

hydroquinone (ISO)

hydroxyurea (ISO)

Lasiocarpine (ISO)

lead(0) (ISO)

N-Nitrosopyrrolidine (ISO)

okadaic acid (ISO)

oxcarbazepine (EXP)

ozone (ISO)

palbociclib (ISO)

paracetamol (EXP,ISO)

PCB138 (ISO)

perfluorononanoic acid (ISO)

perfluorooctane-1-sulfonic acid (ISO)

phenobarbital (ISO)

potassium chromate (ISO)

quercetin (ISO)

resveratrol (ISO)

riddelliine (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sulforaphane (ISO)

sunitinib (ISO)

tert-butyl hydroperoxide (ISO)

tetrachloromethane (ISO)

thioacetamide (EXP)

topotecan (ISO)

trichloroethene (EXP)

triphenyl phosphate (ISO)

trovafloxacin (ISO)

valproic acid (ISO)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell division (IEA)

regulation of mitotic nuclear division (IBA,IEA,ISO,ISS)

regulation of mitotic spindle organization (IBA,IEA,ISO,ISS)

regulation of protein localization (IEA,ISO,ISS)

Cellular Component

cytoplasm (IBA)

meiotic spindle (ISO)

nucleus (IBA)

Molecular Function

protein binding (ISO)

protein kinase binding (IBA,IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
4.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:15489334	PMID:16890155	PMID:18521620	PMID:18615013	PMID:23610072

Genomics

Comparative Map Data

Bora
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	82,205,467 - 82,243,499 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	15	82,205,697 - 82,244,052 (+)	Ensembl				GRCr8
mRatBN7.2	15	75,797,624 - 75,835,599 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	75,797,891 - 75,821,322 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	15	79,780,918 - 79,805,541 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	15	80,857,536 - 80,882,159 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	15	77,805,079 - 77,829,702 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	15	83,442,217 - 83,463,737 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	83,442,144 - 83,463,717 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	15	86,953,333 - 86,975,601 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	15	82,829,209 - 82,852,061 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	15	75,035,699 - 75,061,119 (+)	NCBI		Celera
RGSC_v3.1	15	82,844,988 - 82,867,842 (+)	NCBI
Cytogenetic Map	15	q21	NCBI

BORA
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	13	72,727,923 - 72,756,196 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	13	72,727,749 - 72,756,198 (+)	Ensembl			hg38	GRCh38
GRCh37	13	73,302,061 - 73,330,334 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	13	72,200,043 - 72,228,329 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	13	54,200,530 - 54,228,790 (+)	NCBI		Celera
Cytogenetic Map	13	q21.33	NCBI
HuRef	13	53,999,585 - 54,027,635 (+)	NCBI		HuRef
CHM1_1	13	73,269,762 - 73,298,008 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	13	71,949,448 - 71,977,692 (+)	NCBI		T2T-CHM13v2.0

Bora
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	99,283,880 - 99,311,976 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	99,283,658 - 99,311,976 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	14	99,046,377 - 99,074,540 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	99,046,222 - 99,074,540 (+)	Ensembl			mm10	GRCm38
MGSCv37	14	99,445,596 - 99,473,326 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	14	97,929,511 - 97,957,241 (+)	NCBI		MGSCv36	mm8
Celera	14	97,720,752 - 97,749,866 (+)	NCBI		Celera
Cytogenetic Map	14	E2.2	NCBI
cM Map	14	49.23	NCBI

Bora
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955404	33,924,533 - 33,946,346 (-)	Ensembl
ChiLan1.0	NW_004955404	33,923,496 - 33,946,113 (-)	NCBI	ChiLan1.0	ChiLan1.0

BORA
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	14	74,307,848 - 74,337,454 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	13	72,899,069 - 72,927,715 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	13	53,956,913 - 53,985,355 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	13	72,733,006 - 72,761,432 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	13	72,733,006 - 72,761,432 (+)	Ensembl			panPan2	panpan1.1

BORA
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	22	26,880,351 - 26,906,226 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	22	26,879,933 - 26,906,278 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	22	26,735,652 - 26,762,114 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	22	27,211,177 - 27,237,646 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	22	27,211,198 - 27,237,661 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	22	26,873,278 - 26,899,746 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	22	26,912,735 - 26,939,190 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	22	26,984,118 - 27,010,590 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Bora
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	132,690,249 - 132,717,450 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936511	8,107,756 - 8,134,683 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936511	8,107,476 - 8,134,677 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

BORA
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	11	45,018,333 - 45,045,126 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	11	45,017,651 - 45,045,127 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	11	49,564,863 - 49,592,665 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

BORA
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	3	51,860,304 - 51,888,410 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	3	51,860,405 - 51,887,416 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666046	7,954,590 - 7,982,558 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Bora
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624751	27,789,093 - 27,815,445 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624751	27,788,754 - 27,814,986 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Bora
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	12	25,441,525 - 25,466,954 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Bora
188 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	29
Count of miRNA genes:	24
Interacting mature miRNAs:	27
Transcripts:	ENSRNOT00000039344
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1576315	Schws6	Schwannoma susceptibility QTL 6		0.0069	nervous system integrity trait (VT:0010566)	post-insult time of death (CMO:0002005)	15	60213984	105213984	Rat
1300144	Rf23	Renal function QTL 23	3.61		renal blood flow trait (VT:2000006)	absolute change in renal vascular resistance (CMO:0001900)	15	44806773	104695021	Rat
1549844	Bss7	Bone structure and strength QTL 7	6.4		femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	15	82194914	108192169	Rat
61477	Aia4	Adjuvant induced arthritis QTL 4	3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	15	62440892	97773284	Rat
2300326	Plaw1	Placental weight QTL 1	15	0.005	placenta mass (VT:0004257)	placenta wet weight (CMO:0002088)	15	74735564	106469153	Rat
70182	BpQTLcluster12	Blood pressure QTL cluster 12	3.53		arterial blood pressure trait (VT:2000000)	absolute change in mean arterial blood pressure (CMO:0000533)	15	72716871	101425383	Rat
152025253	Hrtrt24	Heart rate QTL 24	3.82		heart pumping trait (VT:2000009)		15	31855803	92671517	Rat
1582227	Gluco30	Glucose level QTL 30	3.6	0.0003	blood glucose amount (VT:0000188)	absolute change in blood glucose level area under curve (CMO:0002034)	15	43677244	88677244	Rat
1582228	Epfw3	Epididymal fat weight QTL 3	4.1	0.0002	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	15	43677244	88677244	Rat
631655	Bp126	Blood pressure QTL 126	4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	15	64571127	108192169	Rat
1578646	Bmd18	Bone mineral density QTL 18	5.2		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	15	25285835	104695021	Rat
1578647	Bmd17	Bone mineral density QTL 17	4		femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	15	25285835	104695021	Rat
61424	Scl1	Serum cholesterol level QTL 1	7.7	0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	15	19155762	87086765	Rat
1598828	Glom14	Glomerulus QTL 14	2.5		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	15	40463152	85463152	Rat
631516	Gluco31	Glucose level QTL 31	7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	15	72716871	101425383	Rat
2298549	Neuinf12	Neuroinflammation QTL 12	3.5		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	15	61710951	106710951	Rat
1331724	Bp223	Blood pressure QTL 223	3.53715		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	15	75928947	101425383	Rat
2317050	Aia24	Adjuvant induced arthritis QTL 24	2.06		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	15	59257087	104257087	Rat
1582242	Gluco28	Glucose level QTL 28	3.3	0.0008	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	15	43677244	88677244	Rat
2313080	Bss65	Bone structure and strength QTL 65	3.9	0.0001	long bone metaphysis morphology trait (VT:0000133)	tibia midshaft total cross-sectional area (CMO:0001715)	15	67399137	108192169	Rat
1582244	Bw79	Body weight QTL 79	4	0.0002	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	15	43677244	88677244	Rat
1578660	Bss19	Bone structure and strength QTL 19	4.3		femur morphology trait (VT:0000559)	bone trabecular cross-sectional area (CMO:0002311)	15	25285835	104695021	Rat
2317055	Aia10	Adjuvant induced arthritis QTL 10	3.41		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	15	82194914	108192169	Rat
1582214	Stl21	Serum triglyceride level QTL 21	3.1	0.022	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	15	43677244	88677244	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	66	162	91	90	59	90	59	6	351	189	11	141	79	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001013997	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017599714	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039093375	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039093376	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039093377	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005493734	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC088204	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473951	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000015	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000039344 ⟹ ENSRNOP00000035098

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	15	82,205,697 - 82,229,168 (+)	Ensembl
mRatBN7.2 Ensembl	15	75,797,891 - 75,821,322 (+)	Ensembl
Rnor_6.0 Ensembl	15	83,442,144 - 83,463,717 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000102440 ⟹ ENSRNOP00000083042

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	15	82,205,697 - 82,244,052 (+)	Ensembl
mRatBN7.2 Ensembl	15	75,797,891 - 75,821,322 (+)	Ensembl

RefSeq Acc Id:

NM_001013997 ⟹ NP_001014019

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	82,205,720 - 82,228,594 (+)	NCBI
mRatBN7.2	15	75,797,873 - 75,820,747 (+)	NCBI
Rnor_6.0	15	83,442,361 - 83,463,737 (+)	NCBI
Rnor_5.0	15	86,953,333 - 86,975,601 (+)	NCBI
RGSC_v3.4	15	82,829,209 - 82,852,061 (+)	RGD
Celera	15	75,035,699 - 75,061,119 (+)	RGD

Sequence:

show sequence

GCCTGCGGTGGGCCCTGCGGGGTGCTAGAACTTCCACGTTACCCACGAATGTCGGTACGTCCTC
CGTGGCCCCAGGCCTGGACTCCTGTCTCGAGTTGGACCGCTCTGGTTTCCTGGCTGCAGACGTG
CCTGTGCGCTCGCCTAGGTGTGAAGGGGAGCAGAGAGAGGGACGCCTGGAAGCTGAATGGTCGC
TGGAAGTGACGTCCCTGCTGGTACGGAGGGAGCCCGCTCAACTTTGGTCTTCCAAAATTTGCTT
CCTGGGCTATGGGAGATGTCAGCGAATTAAAAATGCAAATAACACCAGCAACTCCAGGAAGGAT
CCCTGTTTTAAATCCCTTTGAAAGTCCCAGTGATTATTCTAATCTCCATGAACAAACCCTTGCT
AGTCCTTCTGTCTTTAAGTCCACAAAACTACCAACTCCAGGGGAATTTAGGTGGTCTATTGATC
AGCTGGCTGTAATAAATCCTGTAGAAATAGACCCAGAGGAGATTCATCGTCAGGCTTCCTACTT
AAGTCTTTCTCGAATAGATAAAGATGTGGAAGACAAAAGACAAAAGGCCATTGAAGAGTTTTTT
ACTAAAGATGTCATTGTGCCCTCGCCCTGGACCGATCATGATGGAAAACAGCCTTCCGAGCTTC
ATCCCAGTAAATGCCTAACTAGCAATGGTGACTCTCCTGTTGGGAAAAAGCCGAGTCTCCCTTC
TCAGAAATGCAATGCTGCCTGCCAGACTCTGTTGTCTCTTCCTGTGGATTTTAATTTGGAAGCC
GTATTAGGAGACTACTTTAGAGCGGATGACTCTGTGGACCAATCTCCCGGGAACCTCAGTTCTT
CGTCTCTCAGGAGAAAGCTCTTTTTAGACGTGAATGGGAGCATCTCCGACTCCTTACCTTCAGC
TTCTCCCAGAAGTCCTCCCAACAGTGCCCGAGGATCTCTTGAGGGACAGTTTTCTTCCAGCCCC
ATTCAGAACAATGCAAAAAAGTACAGTTTGGGAAGCTTAACCACCAGCCCATCGGCTATCTGTT
CACCTACGTTCTCACCAATTGCACTTCAAGTAGGAAAGACACCACTGTCAGAGCACAGGAAGTT
TACATTTCATTCTCCTGAAGCTTCCTCTGGAGGAAGTTCTACTGGGATTGCTAATCCAAGCATC
AGGAGTCCATATATAGATGGCTGCTCACCAATTAAAAATTGGTCTCCTCGGGGACTCAGAGGTG
GTCCTCAGTATTTGTCGTCACTGATTCGGGTACCTTTTGCTCTTGAGACTCACAGTGAAGATGA
AGAAGACAACGTTTCCTCCACAGATGTGGCTGCACTGGGCACAAATGCTGTGGCAGCCCCCCTT
CAGCAGTTGGACTGTGAGCCTTTGGCTTGTGGCGACCCTTTCGTTGTCAGTGCCATGCCTGTCA
CTCAGAGTCAGTCTAGTACCTGTGAGAAAGACCTAGGGCTGCTGGGGGACTTTGAAAGTGAAAG
GGACCATGACACCGTGGATATGGTCGATCCGATAGACACAGCGGATGAAAGCACGTGGATAAAA
GAGCCCGTGGGTAATGGGAATTCACCCATGGCTGAGTTTGTGAGTGGAATTGCCTTCAGCATTG
AGAACTCCCACATGTGCATGTCACCTCTTGCAGAGAGCAGTGTTCTGCCCTGTGAAAGCAGTAA
TGTCCAGATGGACAGTGGCTATAACACACAGACTTGTGGAAGTAATATCACTGATATTGTTGGG
ACAGAAAGCTACTGCAAAGAAAATGTCACACAGTCCTTTGAAGCACAAATGAAACCTCAAGTTA
ATAACATAAAGCAAGATCACACTGTGCAGAGGTGTTGGATGAAAACTACAAGTCCATCTCAGTG
CAGCAGCCTGTAGTCTCAAGACCAAAGACTGCCACTCAATAGTCCCTGACGTATTTATAGGGGA
CTTCGAGTTAATGTGATGGTGATGGGGGTACCTGCTTCACATAATATGCCTAGTTCCCTCCTTA
ATGTGAAAAGCTGCAAAGGAAATTATGACAGGACCAGATGCTCCAAGTTGTTAAAGTACACATT
TATTTTTTAAAAATCAATAAATATTTTTATATTTGCAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039093375 ⟹ XP_038949303

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	82,205,467 - 82,228,594 (+)	NCBI
mRatBN7.2	15	75,797,624 - 75,820,747 (+)	NCBI

RefSeq Acc Id:

XM_039093376 ⟹ XP_038949304

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	82,205,467 - 82,243,499 (+)	NCBI
mRatBN7.2	15	75,797,624 - 75,835,599 (+)	NCBI

RefSeq Acc Id:

XM_039093377 ⟹ XP_038949305

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	82,220,874 - 82,228,594 (+)	NCBI
mRatBN7.2	15	75,807,883 - 75,820,747 (+)	NCBI

RefSeq Acc Id:

XR_005493734

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	82,205,467 - 82,224,113 (+)	NCBI
mRatBN7.2	15	75,797,624 - 75,816,752 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001014019	(Get FASTA)	NCBI Sequence Viewer
	XP_038949303	(Get FASTA)	NCBI Sequence Viewer
	XP_038949304	(Get FASTA)	NCBI Sequence Viewer
	XP_038949305	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH88204	(Get FASTA)	NCBI Sequence Viewer
	EDM02417	(Get FASTA)	NCBI Sequence Viewer
	EDM02418	(Get FASTA)	NCBI Sequence Viewer
	EDM02419	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000035098
	ENSRNOP00000035098.3
	ENSRNOP00000083042
GenBank Protein	Q5M864	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001014019 ⟸ NM_001013997

- UniProtKB:

Q5M864 (UniProtKB/Swiss-Prot), A6HU54 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MGDVSELKMQITPATPGRIPVLNPFESPSDYSNLHEQTLASPSVFKSTKLPTPGEFRWSIDQLA
VINPVEIDPEEIHRQASYLSLSRIDKDVEDKRQKAIEEFFTKDVIVPSPWTDHDGKQPSELHPS
KCLTSNGDSPVGKKPSLPSQKCNAACQTLLSLPVDFNLEAVLGDYFRADDSVDQSPGNLSSSSL
RRKLFLDVNGSISDSLPSASPRSPPNSARGSLEGQFSSSPIQNNAKKYSLGSLTTSPSAICSPT
FSPIALQVGKTPLSEHRKFTFHSPEASSGGSSTGIANPSIRSPYIDGCSPIKNWSPRGLRGGPQ
YLSSLIRVPFALETHSEDEEDNVSSTDVAALGTNAVAAPLQQLDCEPLACGDPFVVSAMPVTQS
QSSTCEKDLGLLGDFESERDHDTVDMVDPIDTADESTWIKEPVGNGNSPMAEFVSGIAFSIENS
HMCMSPLAESSVLPCESSNVQMDSGYNTQTCGSNITDIVGTESYCKENVTQSFEAQMKPQVNNI
KQDHTVQRCWMKTTSPSQCSSL

hide sequence

Ensembl Acc Id:

ENSRNOP00000035098 ⟸ ENSRNOT00000039344

RefSeq Acc Id:	XP_038949304 ⟸ XM_039093376
- Peptide Label:	isoform X2
- UniProtKB:	A6HU54 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038949303 ⟸ XM_039093375
- Peptide Label:	isoform X1
- UniProtKB:	Q5M864 (UniProtKB/Swiss-Prot), A6HU54 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038949305 ⟸ XM_039093377
- Peptide Label:	isoform X3

Ensembl Acc Id:

ENSRNOP00000083042 ⟸ ENSRNOT00000102440

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5M864-F1-model_v2	AlphaFold	Q5M864	1-534	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13699859

Promoter ID:

EPDNEW_R10383

Type:

initiation region

Name:

Bora_1

Description:

bora, aurora kinase A activator

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	15	83,442,387 - 83,442,447	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1309522	AgrOrtholog
BioCyc Gene	G2FUF-12789	BioCyc
Ensembl Genes	ENSRNOG00000024798	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000039344	ENTREZGENE
	ENSRNOT00000039344.5	UniProtKB/Swiss-Prot
	ENSRNOT00000102440	ENTREZGENE
IMAGE_CLONE	IMAGE:7380234	IMAGE-MGC_LOAD
InterPro	Aurora_borealis_protein	UniProtKB/Swiss-Prot
KEGG Report	rno:306102	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:108900	IMAGE-MGC_LOAD
NCBI Gene	306102	ENTREZGENE
PANTHER	PROTEIN AURORA BOREALIS	UniProtKB/Swiss-Prot
	PTHR14728	UniProtKB/Swiss-Prot
Pfam	BORA_N	UniProtKB/Swiss-Prot
PhenoGen	Bora	PhenoGen
PRINTS	AURORABORA	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000024798	RatGTEx
UniProt	A0A8I5ZVR5_RAT	UniProtKB/TrEMBL
	A6HU54	ENTREZGENE, UniProtKB/TrEMBL
	BORA_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2011-09-02	Bora	bora, aurora kinase A activator	RGD1309522	similar to hypothetical protein FLJ22624	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	RGD1309522	similar to hypothetical protein FLJ22624	RGD1309522_predicted	similar to hypothetical protein FLJ22624 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-20	RGD1309522_predicted	similar to hypothetical protein FLJ22624 (predicted)	LOC306102_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC306102_predicted	similar to hypothetical protein FLJ22624 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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