Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Teratozoospermia | | ISO | NECTIN3 (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:28689229 | |
|
Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Teratozoospermia | | ISO | NECTIN3 (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:28689229 | |
|
|
|
|
|
|
|
|
|
|
# | Reference Title | Reference Citation |
1. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
2. | Rat ISS GO annotations from MGI mouse gene data--August 2006 | MGD data from the GO Consortium |
3. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
4. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
5. | Interneurite affinity is regulated by heterophilic nectin interactions in concert with the cadherin machinery. | Togashi H, etal., J Cell Biol. 2006 Jul 3;174(1):141-51. Epub 2006 Jun 26. |
PMID:10744716 | PMID:11827984 | PMID:12438620 | PMID:12515806 | PMID:12740392 | PMID:12759359 | PMID:12826663 | PMID:15328010 | PMID:15660130 | PMID:15728677 | PMID:16249236 | PMID:22512338 |
PMID:22902367 | PMID:23073828 | PMID:23533177 | PMID:23990464 | PMID:25232752 | PMID:27044745 | PMID:27217376 | PMID:28176461 |
Nectin3 (Rattus norvegicus - Norway rat) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
NECTIN3 (Homo sapiens - human) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Nectin3 (Mus musculus - house mouse) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Nectin3 (Chinchilla lanigera - long-tailed chinchilla) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
NECTIN3 (Pan paniscus - bonobo/pygmy chimpanzee) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
NECTIN3 (Canis lupus familiaris - dog) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Nectin3 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
NECTIN3 (Sus scrofa - pig) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
NECTIN3 (Chlorocebus sabaeus - green monkey) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Nectin3 (Heterocephalus glaber - naked mole-rat) |
|
.
Variants in Nectin3
278 total Variants |
The detailed report is available here: | Full Report | CSV | TAB | Printer | ||||
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
The following QTLs overlap with this region. | Full Report | CSV | TAB | Printer | Gviewer |
BF386882 |
|
||||||||||||||||||||||||||||||||||||||||
RH12011 |
|
||||||||||||||||||||||||||||||||||||||||
RH133661 |
|
||||||||||||||||||||||||||||||||||||||||
BE111876 |
|
||||||||||||||||||||||||||||||||||||||||
RH137470 |
|
||||||||||||||||||||||||||||||||||||||||
PVRL3__5617 |
|
alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
High | |||||||||||||
Medium | 3 | 29 | 34 | 29 | 29 | 2 | 2 | 74 | 34 | 41 | 11 | 2 | |
Low | 14 | 23 | 12 | 19 | 12 | 6 | 8 | 1 | 6 | ||||
Below cutoff | 1 |
RefSeq Transcripts | NM_001105883 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
NM_001399228 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_006248338 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039088189 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063270397 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063270398 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063270399 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063270400 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063270401 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063270402 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063270403 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063270404 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063270405 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XR_001840409 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XR_001840410 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XR_358269 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
GenBank Nucleotide | CH473967 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
FQ221474 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
JAXUCZ010000011 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
RefSeq Acc Id: | ENSRNOT00000002957 ⟹ ENSRNOP00000002957 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
|
RefSeq Acc Id: | ENSRNOT00000102870 ⟹ ENSRNOP00000096764 | ||||||||
Type: | CODING | ||||||||
Position: |
|
RefSeq Acc Id: | ENSRNOT00000115289 ⟹ ENSRNOP00000082293 | ||||||||
Type: | CODING | ||||||||
Position: |
|
RefSeq Acc Id: | ENSRNOT00000119871 ⟹ ENSRNOP00000089435 | ||||||||
Type: | CODING | ||||||||
Position: |
|
RefSeq Acc Id: | NM_001105883 ⟹ NP_001099353 | ||||||||||||||||||||||||||||
RefSeq Status: | VALIDATED | ||||||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||||||
Position: |
|
||||||||||||||||||||||||||||
Sequence: |
RefSeq Acc Id: | NM_001399228 ⟹ NP_001386157 | ||||||||||||
RefSeq Status: | VALIDATED | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
|
RefSeq Acc Id: | XM_039088189 ⟹ XP_038944117 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
|
RefSeq Acc Id: | XM_063270397 ⟹ XP_063126467 | ||||||||
Type: | CODING | ||||||||
Position: |
|
RefSeq Acc Id: | XM_063270398 ⟹ XP_063126468 | ||||||||
Type: | CODING | ||||||||
Position: |
|
RefSeq Acc Id: | XM_063270399 ⟹ XP_063126469 | ||||||||
Type: | CODING | ||||||||
Position: |
|
RefSeq Acc Id: | XM_063270400 ⟹ XP_063126470 | ||||||||
Type: | CODING | ||||||||
Position: |
|
RefSeq Acc Id: | XM_063270401 ⟹ XP_063126471 | ||||||||
Type: | CODING | ||||||||
Position: |
|
RefSeq Acc Id: | XM_063270402 ⟹ XP_063126472 | ||||||||
Type: | CODING | ||||||||
Position: |
|
RefSeq Acc Id: | XM_063270403 ⟹ XP_063126473 | ||||||||
Type: | CODING | ||||||||
Position: |
|
RefSeq Acc Id: | XM_063270404 ⟹ XP_063126474 | ||||||||
Type: | CODING | ||||||||
Position: |
|
RefSeq Acc Id: | XM_063270405 ⟹ XP_063126475 | ||||||||
Type: | CODING | ||||||||
Position: |
|
Protein RefSeqs | NP_001099353 | (Get FASTA) | NCBI Sequence Viewer |
NP_001386157 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038944117 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063126467 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063126468 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063126469 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063126470 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063126471 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063126472 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063126473 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063126474 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063126475 | (Get FASTA) | NCBI Sequence Viewer | |
GenBank Protein | EDM11119 | (Get FASTA) | NCBI Sequence Viewer |
EDM11121 | (Get FASTA) | NCBI Sequence Viewer | |
Ensembl Protein | ENSRNOP00000002957.6 | ||
ENSRNOP00000082293 | |||
ENSRNOP00000082293.1 | |||
ENSRNOP00000089435.1 | |||
ENSRNOP00000096764 | |||
ENSRNOP00000096764.1 |
RefSeq Acc Id: | NP_001099353 ⟸ NM_001105883 |
- Peptide Label: | isoform 2 |
- UniProtKB: | A6IQW6 (UniProtKB/TrEMBL), A0A8I6APZ5 (UniProtKB/TrEMBL), A6IQW7 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | ENSRNOP00000002957 ⟸ ENSRNOT00000002957 |
RefSeq Acc Id: | XP_038944117 ⟸ XM_039088189 |
- Peptide Label: | isoform X1 |
- UniProtKB: | D4A5C0 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | ENSRNOP00000082293 ⟸ ENSRNOT00000115289 |
RefSeq Acc Id: | ENSRNOP00000089435 ⟸ ENSRNOT00000119871 |
RefSeq Acc Id: | ENSRNOP00000096764 ⟸ ENSRNOT00000102870 |
RefSeq Acc Id: | NP_001386157 ⟸ NM_001399228 |
- Peptide Label: | isoform 1 |
- UniProtKB: | A0A8I5ZU75 (UniProtKB/TrEMBL), A6IQW8 (UniProtKB/TrEMBL), D4A5C0 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | XP_063126471 ⟸ XM_063270401 |
- Peptide Label: | isoform X6 |
RefSeq Acc Id: | XP_063126470 ⟸ XM_063270400 |
- Peptide Label: | isoform X5 |
RefSeq Acc Id: | XP_063126469 ⟸ XM_063270399 |
- Peptide Label: | isoform X4 |
RefSeq Acc Id: | XP_063126467 ⟸ XM_063270397 |
- Peptide Label: | isoform X2 |
RefSeq Acc Id: | XP_063126468 ⟸ XM_063270398 |
- Peptide Label: | isoform X3 |
RefSeq Acc Id: | XP_063126474 ⟸ XM_063270404 |
- Peptide Label: | isoform X9 |
RefSeq Acc Id: | XP_063126472 ⟸ XM_063270402 |
- Peptide Label: | isoform X7 |
RefSeq Acc Id: | XP_063126475 ⟸ XM_063270405 |
- Peptide Label: | isoform X10 |
RefSeq Acc Id: | XP_063126473 ⟸ XM_063270403 |
- Peptide Label: | isoform X8 |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-D4A5C0-F1-model_v2 | AlphaFold | D4A5C0 | 1-509 | view protein structure |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
Database | Acc Id | Source(s) |
AGR Gene | RGD:1309516 | AgrOrtholog |
BioCyc Gene | G2FUF-21398 | BioCyc |
Ensembl Genes | ENSRNOG00000002176 | Ensembl, ENTREZGENE, UniProtKB/TrEMBL |
Ensembl Transcript | ENSRNOT00000002957.6 | UniProtKB/TrEMBL |
ENSRNOT00000102870 | ENTREZGENE | |
ENSRNOT00000102870.1 | UniProtKB/TrEMBL | |
ENSRNOT00000115289 | ENTREZGENE | |
ENSRNOT00000115289.1 | UniProtKB/TrEMBL | |
ENSRNOT00000119871.1 | UniProtKB/TrEMBL | |
Gene3D-CATH | 2.60.40.10 | UniProtKB/TrEMBL |
InterPro | CD80_C2-set | UniProtKB/TrEMBL |
Ig-like | UniProtKB/TrEMBL | |
Ig-like_dom_sf | UniProtKB/TrEMBL | |
Ig-like_fold | UniProtKB/TrEMBL | |
Ig_sub | UniProtKB/TrEMBL | |
Ig_V-set | UniProtKB/TrEMBL | |
IgC1_2_Nectin-3-4-like | UniProtKB/TrEMBL | |
Nectin-3 | UniProtKB/TrEMBL | |
KEGG Report | rno:288124 | UniProtKB/TrEMBL |
NCBI Gene | 288124 | ENTREZGENE |
PANTHER | NECTIN-RELATED | UniProtKB/TrEMBL |
PTHR23277:SF12 | UniProtKB/TrEMBL | |
Pfam | C2-set_2 | UniProtKB/TrEMBL |
V-set | UniProtKB/TrEMBL | |
PhenoGen | Nectin3 | PhenoGen |
PROSITE | IG_LIKE | UniProtKB/TrEMBL |
RatGTEx | ENSRNOG00000002176 | RatGTEx |
SMART | SM00409 | UniProtKB/TrEMBL |
Superfamily-SCOP | SSF48726 | UniProtKB/TrEMBL |
UniProt | A0A8I5ZU75 | ENTREZGENE, UniProtKB/TrEMBL |
A0A8I6ABQ5_RAT | UniProtKB/TrEMBL | |
A0A8I6APZ5 | ENTREZGENE, UniProtKB/TrEMBL | |
A6IQW6 | ENTREZGENE, UniProtKB/TrEMBL | |
A6IQW7 | ENTREZGENE, UniProtKB/TrEMBL | |
A6IQW8 | ENTREZGENE, UniProtKB/TrEMBL | |
D4A5C0 | ENTREZGENE, UniProtKB/TrEMBL |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
---|---|---|---|---|---|---|---|
2016-02-17 | Nectin3 | nectin cell adhesion molecule 3 | Pvrl3 | poliovirus receptor-related 3 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2008-04-30 | Pvrl3 | poliovirus receptor-related 3 | Pvrl3_predicted | poliovirus receptor-related 3 (predicted) | 'predicted' is removed | 2292626 | APPROVED |
2005-01-12 | Pvrl3_predicted | poliovirus receptor-related 3 (predicted) | Symbol and Name status set to approved | 70820 | APPROVED |