Nectin3 (nectin cell adhesion molecule 3) - Rat Genome Database

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Gene: Nectin3 (nectin cell adhesion molecule 3) Rattus norvegicus
Analyze
Symbol: Nectin3
Name: nectin cell adhesion molecule 3
RGD ID: 1309516
Description: Predicted to enable cell adhesion molecule binding activity and protein homodimerization activity. Predicted to be involved in establishment of protein localization to plasma membrane; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; and homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to act upstream of or within several processes, including camera-type eye morphogenesis; fertilization; and protein localization to cell junction. Located in axon and dendrite. Orthologous to human NECTIN3 (nectin cell adhesion molecule 3); INTERACTS WITH 1,3-dinitrobenzene; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC288124; nectin-3; poliovirus receptor-related 3; poliovirus receptor-related protein 3; Pvrl3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81167,825,296 - 67,931,999 (+)NCBIGRCr8
mRatBN7.21154,362,712 - 54,469,351 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1154,364,487 - 54,462,519 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1163,127,098 - 63,232,154 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01155,788,938 - 55,893,999 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01154,896,828 - 55,001,808 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01157,897,879 - 57,995,193 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1157,897,879 - 57,993,548 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01162,049,050 - 62,146,379 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41155,843,801 - 55,940,634 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11155,901,379 - 55,946,114 (+)NCBI
Celera1153,897,883 - 53,994,695 (+)NCBICelera
Cytogenetic Map11q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1,3-dinitrobenzene  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
8-Br-cAMP  (ISO)
acetamide  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
beta-naphthoflavone  (ISO)
bisphenol A  (EXP,ISO)
buspirone  (EXP)
cadmium atom  (ISO)
caffeine  (ISO)
chloroprene  (ISO)
choline  (ISO)
clofibric acid  (EXP)
cobalt dichloride  (EXP)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
decabromodiphenyl ether  (EXP)
diarsenic trioxide  (ISO)
dibenz[a,h]anthracene  (ISO)
dichloromethane  (EXP)
dicrotophos  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
ethanol  (ISO)
ethylbenzene  (EXP)
flutamide  (EXP)
folic acid  (ISO)
FR900359  (ISO)
glafenine  (EXP)
ketamine  (EXP)
L-methionine  (ISO)
leflunomide  (ISO)
lipopolysaccharide  (ISO)
N-nitrosodiethylamine  (EXP)
nefazodone  (EXP)
niclosamide  (ISO)
nimesulide  (EXP)
ouabain  (ISO)
oxaliplatin  (EXP)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
pirinixic acid  (ISO)
propiconazole  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
succimer  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
temozolomide  (ISO)
tetrachloromethane  (ISO)
thapsigargin  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
trichloroethene  (EXP)
triptonide  (ISO)
troglitazone  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Interneurite affinity is regulated by heterophilic nectin interactions in concert with the cadherin machinery. Togashi H, etal., J Cell Biol. 2006 Jul 3;174(1):141-51. Epub 2006 Jun 26.
Additional References at PubMed
PMID:10744716   PMID:11827984   PMID:12438620   PMID:12515806   PMID:12740392   PMID:12759359   PMID:12826663   PMID:15328010   PMID:15660130   PMID:15728677   PMID:16249236   PMID:22512338  
PMID:22902367   PMID:23073828   PMID:23533177   PMID:23990464   PMID:25232752   PMID:27044745   PMID:27217376   PMID:28176461  


Genomics

Comparative Map Data
Nectin3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81167,825,296 - 67,931,999 (+)NCBIGRCr8
mRatBN7.21154,362,712 - 54,469,351 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1154,364,487 - 54,462,519 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1163,127,098 - 63,232,154 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01155,788,938 - 55,893,999 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01154,896,828 - 55,001,808 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01157,897,879 - 57,995,193 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1157,897,879 - 57,993,548 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01162,049,050 - 62,146,379 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41155,843,801 - 55,940,634 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11155,901,379 - 55,946,114 (+)NCBI
Celera1153,897,883 - 53,994,695 (+)NCBICelera
Cytogenetic Map11q21NCBI
NECTIN3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383111,071,816 - 111,194,170 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3111,070,071 - 111,275,563 (+)EnsemblGRCh38hg38GRCh38
GRCh373110,790,663 - 110,913,017 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363112,273,555 - 112,335,752 (+)NCBINCBI36Build 36hg18NCBI36
Build 343112,273,554 - 112,335,752NCBI
Celera3109,190,329 - 109,252,381 (+)NCBICelera
Cytogenetic Map3q13.13NCBI
HuRef3108,164,840 - 108,287,207 (+)NCBIHuRef
CHM1_13110,754,866 - 110,877,275 (+)NCBICHM1_1
T2T-CHM13v2.03113,792,242 - 113,914,605 (+)NCBIT2T-CHM13v2.0
Nectin3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391646,208,028 - 46,318,898 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1646,208,069 - 46,318,888 (-)EnsemblGRCm39 Ensembl
GRCm381646,387,665 - 46,498,535 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1646,387,706 - 46,498,525 (-)EnsemblGRCm38mm10GRCm38
MGSCv371646,395,118 - 46,497,080 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361646,314,342 - 46,416,301 (-)NCBIMGSCv36mm8
Celera1646,777,549 - 46,846,805 (-)NCBICelera
Cytogenetic Map16B5NCBI
cM Map1630.48NCBI
Nectin3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542711,606,909 - 11,724,004 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542711,639,942 - 11,731,910 (+)NCBIChiLan1.0ChiLan1.0
NECTIN3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22109,075,028 - 109,205,819 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13109,079,806 - 109,210,597 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03108,223,380 - 108,354,079 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13115,148,481 - 115,278,563 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3115,148,481 - 115,270,507 (+)Ensemblpanpan1.1panPan2
NECTIN3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13315,868,813 - 16,173,158 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3315,911,411 - 15,933,307 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3315,973,728 - 16,274,980 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03316,032,718 - 16,154,568 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.13315,919,132 - 16,220,406 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03315,972,140 - 16,266,709 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03316,516,552 - 16,812,105 (+)NCBIUU_Cfam_GSD_1.0
Nectin3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602138,471,852 - 138,498,191 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493683486,226 - 109,684 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493683486,195 - 110,686 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NECTIN3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13148,452,309 - 148,579,052 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113148,448,581 - 148,578,920 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213158,456,487 - 158,604,357 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NECTIN3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12269,597,729 - 69,719,397 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2269,598,895 - 69,719,343 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604196,776,500 - 96,905,043 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nectin3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473137,433,809 - 37,568,677 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473137,425,966 - 37,567,938 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Nectin3
278 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:56
Count of miRNA genes:48
Interacting mature miRNAs:50
Transcripts:ENSRNOT00000002957
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)11169446234Rat
1558659Tescar1Testicular tumor resistance QTL 13.9testis integrity trait (VT:0010572)percentage of study population developing testis tumors during a period of time (CMO:0001261)11104193166113562Rat
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)112295940367959403Rat
8694376Bw156Body weight QTL 1562.250.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
9590313Scort20Serum corticosterone level QTL 206.510.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)112328045668280456Rat
9589032Epfw10Epididymal fat weight QTL 109.290.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)112328045668280456Rat
8694424Bw162Body weight QTL 1623.80.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112767241082846715Rat
1300130Rf20Renal function QTL 204.44kidney glomerulus integrity trait (VT:0010546)kidney glomerulus diameter (CMO:0001166)112952841860324829Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)112952841882566702Rat
2298551Neuinf10Neuroinflammation QTL 103.7nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)113123913478851519Rat
70180BpQTLcluster10Blood pressure QTL cluster 103.19arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)113491804179918041Rat
1300135Rf19Renal function QTL 193.38blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)114094618882566702Rat
2312566Glom20Glomerulus QTL 203.60.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)114428575982566702Rat
1581565Pur10Proteinuria QTL 100.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)114480331882846466Rat
1581572Uae35Urinary albumin excretion QTL 350.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)114480331882846466Rat
4889859Pur28Proteinuria QTL 2819.50.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)114545932375190161Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)115445753486241447Rat

Markers in Region
BF386882  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21154,420,167 - 54,420,318 (-)MAPPERmRatBN7.2
Rnor_6.01157,937,717 - 57,937,867NCBIRnor6.0
Rnor_5.01162,088,888 - 62,089,038UniSTSRnor5.0
RGSC_v3.41155,899,485 - 55,899,635UniSTSRGSC3.4
Celera1153,953,547 - 53,953,697UniSTS
RH 3.4 Map4581.7UniSTS
Cytogenetic Map11q21UniSTS
RH12011  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21154,408,037 - 54,408,162 (-)MAPPERmRatBN7.2
Rnor_6.01157,949,873 - 57,949,997NCBIRnor6.0
Rnor_5.01162,101,044 - 62,101,168UniSTSRnor5.0
RGSC_v3.41155,887,352 - 55,887,476UniSTSRGSC3.4
Celera1153,941,436 - 53,941,560UniSTS
Cytogenetic Map11q21UniSTS
RH133661  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21154,410,912 - 54,411,070 (-)MAPPERmRatBN7.2
Rnor_6.01157,946,965 - 57,947,122NCBIRnor6.0
Rnor_5.01162,098,136 - 62,098,293UniSTSRnor5.0
RGSC_v3.41155,890,227 - 55,890,384UniSTSRGSC3.4
Celera1153,944,311 - 53,944,468UniSTS
RH 3.4 Map4621.62UniSTS
Cytogenetic Map11q21UniSTS
BE111876  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21154,414,838 - 54,415,010 (-)MAPPERmRatBN7.2
Rnor_6.01157,943,025 - 57,943,196NCBIRnor6.0
Rnor_5.01162,094,196 - 62,094,367UniSTSRnor5.0
RGSC_v3.41155,894,153 - 55,894,324UniSTSRGSC3.4
Celera1153,948,237 - 53,948,408UniSTS
RH 3.4 Map4581.3UniSTS
Cytogenetic Map11q21UniSTS
RH137470  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21154,409,388 - 54,409,595 (-)MAPPERmRatBN7.2
Rnor_6.01157,948,440 - 57,948,646NCBIRnor6.0
Rnor_5.01162,099,611 - 62,099,817UniSTSRnor5.0
RGSC_v3.41155,888,703 - 55,888,909UniSTSRGSC3.4
Celera1153,942,787 - 53,942,993UniSTS
Cytogenetic Map11q21UniSTS
PVRL3__5617  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21154,407,959 - 54,408,539 (-)MAPPERmRatBN7.2
Rnor_6.01157,949,496 - 57,950,075NCBIRnor6.0
Rnor_5.01162,100,667 - 62,101,246UniSTSRnor5.0
RGSC_v3.41155,887,274 - 55,887,853UniSTSRGSC3.4
Celera1153,941,358 - 53,941,937UniSTS
Cytogenetic Map11q21UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 29 34 29 29 2 2 74 34 41 11 2
Low 14 23 12 19 12 6 8 1 6
Below cutoff 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001105883 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001399228 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006248338 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088189 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270397 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270398 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270399 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270400 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270401 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270402 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270403 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270404 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270405 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001840409 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001840410 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_358269 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH473967 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221474 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000002957   ⟹   ENSRNOP00000002957
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1154,364,487 - 54,420,390 (+)Ensembl
Rnor_6.0 Ensembl1157,897,879 - 57,993,548 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000102870   ⟹   ENSRNOP00000096764
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1154,364,487 - 54,462,519 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000115289   ⟹   ENSRNOP00000082293
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1154,364,487 - 54,410,018 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000119871   ⟹   ENSRNOP00000089435
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1154,408,640 - 54,461,316 (+)Ensembl
RefSeq Acc Id: NM_001105883   ⟹   NP_001099353
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81167,826,944 - 67,931,999 (+)NCBI
mRatBN7.21154,364,296 - 54,469,351 (+)NCBI
Rnor_6.01157,897,879 - 57,993,548 (-)NCBI
Rnor_5.01162,049,050 - 62,146,379 (-)NCBI
RGSC_v3.41155,843,801 - 55,940,634 (+)RGD
Celera1153,897,883 - 53,994,695 (+)RGD
Sequence:
RefSeq Acc Id: NM_001399228   ⟹   NP_001386157
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81167,826,944 - 67,876,731 (+)NCBI
mRatBN7.21154,364,296 - 54,414,083 (+)NCBI
RefSeq Acc Id: XM_039088189   ⟹   XP_038944117
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81167,825,300 - 67,871,452 (+)NCBI
mRatBN7.21154,362,712 - 54,413,560 (+)NCBI
RefSeq Acc Id: XM_063270397   ⟹   XP_063126467
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81167,825,300 - 67,881,282 (+)NCBI
RefSeq Acc Id: XM_063270398   ⟹   XP_063126468
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81167,825,300 - 67,881,282 (+)NCBI
RefSeq Acc Id: XM_063270399   ⟹   XP_063126469
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81167,825,300 - 67,931,228 (+)NCBI
RefSeq Acc Id: XM_063270400   ⟹   XP_063126470
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81167,825,300 - 67,931,228 (+)NCBI
RefSeq Acc Id: XM_063270401   ⟹   XP_063126471
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81167,825,296 - 67,871,452 (+)NCBI
RefSeq Acc Id: XM_063270402   ⟹   XP_063126472
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81167,826,920 - 67,881,282 (+)NCBI
RefSeq Acc Id: XM_063270403   ⟹   XP_063126473
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81167,848,089 - 67,871,452 (+)NCBI
RefSeq Acc Id: XM_063270404   ⟹   XP_063126474
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81167,825,331 - 67,883,033 (+)NCBI
RefSeq Acc Id: XM_063270405   ⟹   XP_063126475
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81167,827,476 - 67,871,452 (+)NCBI
RefSeq Acc Id: NP_001099353   ⟸   NM_001105883
- Peptide Label: isoform 2
- UniProtKB: A6IQW6 (UniProtKB/TrEMBL),   A0A8I6APZ5 (UniProtKB/TrEMBL),   A6IQW7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000002957   ⟸   ENSRNOT00000002957
RefSeq Acc Id: XP_038944117   ⟸   XM_039088189
- Peptide Label: isoform X1
- UniProtKB: D4A5C0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000082293   ⟸   ENSRNOT00000115289
RefSeq Acc Id: ENSRNOP00000089435   ⟸   ENSRNOT00000119871
RefSeq Acc Id: ENSRNOP00000096764   ⟸   ENSRNOT00000102870
RefSeq Acc Id: NP_001386157   ⟸   NM_001399228
- Peptide Label: isoform 1
- UniProtKB: A0A8I5ZU75 (UniProtKB/TrEMBL),   A6IQW8 (UniProtKB/TrEMBL),   D4A5C0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126471   ⟸   XM_063270401
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063126470   ⟸   XM_063270400
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063126469   ⟸   XM_063270399
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063126467   ⟸   XM_063270397
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063126468   ⟸   XM_063270398
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063126474   ⟸   XM_063270404
- Peptide Label: isoform X9
RefSeq Acc Id: XP_063126472   ⟸   XM_063270402
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063126475   ⟸   XM_063270405
- Peptide Label: isoform X10
RefSeq Acc Id: XP_063126473   ⟸   XM_063270403
- Peptide Label: isoform X8
Protein Domains
Ig-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A5C0-F1-model_v2 AlphaFold D4A5C0 1-509 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309516 AgrOrtholog
BioCyc Gene G2FUF-21398 BioCyc
Ensembl Genes ENSRNOG00000002176 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000002957.6 UniProtKB/TrEMBL
  ENSRNOT00000102870 ENTREZGENE
  ENSRNOT00000102870.1 UniProtKB/TrEMBL
  ENSRNOT00000115289 ENTREZGENE
  ENSRNOT00000115289.1 UniProtKB/TrEMBL
  ENSRNOT00000119871.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro CD80_C2-set UniProtKB/TrEMBL
  Ig-like UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_V-set UniProtKB/TrEMBL
  IgC1_2_Nectin-3-4-like UniProtKB/TrEMBL
  Nectin-3 UniProtKB/TrEMBL
KEGG Report rno:288124 UniProtKB/TrEMBL
NCBI Gene 288124 ENTREZGENE
PANTHER NECTIN-RELATED UniProtKB/TrEMBL
  PTHR23277:SF12 UniProtKB/TrEMBL
Pfam C2-set_2 UniProtKB/TrEMBL
  V-set UniProtKB/TrEMBL
PhenoGen Nectin3 PhenoGen
PROSITE IG_LIKE UniProtKB/TrEMBL
RatGTEx ENSRNOG00000002176 RatGTEx
SMART SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
UniProt A0A8I5ZU75 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ABQ5_RAT UniProtKB/TrEMBL
  A0A8I6APZ5 ENTREZGENE, UniProtKB/TrEMBL
  A6IQW6 ENTREZGENE, UniProtKB/TrEMBL
  A6IQW7 ENTREZGENE, UniProtKB/TrEMBL
  A6IQW8 ENTREZGENE, UniProtKB/TrEMBL
  D4A5C0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-17 Nectin3  nectin cell adhesion molecule 3  Pvrl3  poliovirus receptor-related 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Pvrl3  poliovirus receptor-related 3   Pvrl3_predicted  poliovirus receptor-related 3 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Pvrl3_predicted  poliovirus receptor-related 3 (predicted)      Symbol and Name status set to approved 70820 APPROVED