NECTIN3 (nectin cell adhesion molecule 3) - Rat Genome Database

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Gene: NECTIN3 (nectin cell adhesion molecule 3) Sus scrofa
Analyze
Symbol: NECTIN3
Name: nectin cell adhesion molecule 3
RGD ID: 14275541
Description: ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN cell adhesion (ortholog); cell-cell adhesion (ortholog); fertilization (ortholog); ASSOCIATED WITH cataract (ortholog); genetic disease (ortholog); Teratozoospermia (ortholog); FOUND IN axon (ortholog); dendrite (ortholog); hippocampal mossy fiber to CA3 synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: nectin-3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13148,452,309 - 148,579,052 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113148,448,581 - 148,578,920 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213158,456,487 - 158,604,357 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
NECTIN3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13148,452,309 - 148,579,052 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113148,448,581 - 148,578,920 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213158,456,487 - 158,604,357 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NECTIN3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383111,071,816 - 111,194,170 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3111,070,071 - 111,275,563 (+)EnsemblGRCh38hg38GRCh38
GRCh373110,790,663 - 110,913,017 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363112,273,555 - 112,335,752 (+)NCBINCBI36Build 36hg18NCBI36
Build 343112,273,554 - 112,335,752NCBI
Celera3109,190,329 - 109,252,381 (+)NCBICelera
Cytogenetic Map3q13.13NCBI
HuRef3108,164,840 - 108,287,207 (+)NCBIHuRef
CHM1_13110,754,866 - 110,877,275 (+)NCBICHM1_1
T2T-CHM13v2.03113,792,242 - 113,914,605 (+)NCBIT2T-CHM13v2.0
Nectin3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391646,208,028 - 46,318,898 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1646,208,069 - 46,318,888 (-)EnsemblGRCm39 Ensembl
GRCm381646,387,665 - 46,498,535 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1646,387,706 - 46,498,525 (-)EnsemblGRCm38mm10GRCm38
MGSCv371646,395,118 - 46,497,080 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361646,314,342 - 46,416,301 (-)NCBIMGSCv36mm8
Celera1646,777,549 - 46,846,805 (-)NCBICelera
Cytogenetic Map16B5NCBI
cM Map1630.48NCBI
Nectin3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81167,825,296 - 67,931,999 (+)NCBIGRCr8
mRatBN7.21154,362,712 - 54,469,351 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1154,364,487 - 54,462,519 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1163,127,098 - 63,232,154 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01155,788,938 - 55,893,999 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01154,896,828 - 55,001,808 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01157,897,879 - 57,995,193 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1157,897,879 - 57,993,548 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01162,049,050 - 62,146,379 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41155,843,801 - 55,940,634 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11155,901,379 - 55,946,114 (+)NCBI
Celera1153,897,883 - 53,994,695 (+)NCBICelera
Cytogenetic Map11q21NCBI
Nectin3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542711,606,909 - 11,724,004 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542711,639,942 - 11,731,910 (+)NCBIChiLan1.0ChiLan1.0
NECTIN3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22109,075,028 - 109,205,819 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13109,079,806 - 109,210,597 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03108,223,380 - 108,354,079 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13115,148,481 - 115,278,563 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3115,148,481 - 115,270,507 (+)Ensemblpanpan1.1panPan2
NECTIN3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13315,868,813 - 16,173,158 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3315,911,411 - 15,933,307 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3315,973,728 - 16,274,980 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03316,032,718 - 16,154,568 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.13315,919,132 - 16,220,406 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03315,972,140 - 16,266,709 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03316,516,552 - 16,812,105 (+)NCBIUU_Cfam_GSD_1.0
Nectin3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602138,471,852 - 138,498,191 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493683486,226 - 109,684 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493683486,195 - 110,686 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NECTIN3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12269,597,729 - 69,719,397 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2269,598,895 - 69,719,343 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604196,776,500 - 96,905,043 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nectin3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473137,433,809 - 37,568,677 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473137,425,966 - 37,567,938 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in NECTIN3
2459 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 10 1 2 1 13 2
Low 3 1 4 2 10 3 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000013057   ⟹   ENSSSCP00000012713
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl13148,499,206 - 148,579,160 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000034662   ⟹   ENSSSCP00000029129
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl13148,452,309 - 148,579,052 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000055651   ⟹   ENSSSCP00000050589
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl13148,506,691 - 148,578,830 (-)Ensembl
RefSeq Acc Id: XM_021070394   ⟹   XP_020926053
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.113148,507,142 - 148,578,915 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021070395   ⟹   XP_020926054
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.113148,448,581 - 148,578,920 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020926054   ⟸   XM_021070395
- Peptide Label: isoform X2
- UniProtKB: A0A4X1U8F1 (UniProtKB/TrEMBL),   A0A8D0YAS4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020926053   ⟸   XM_021070394
- Peptide Label: isoform X1
- UniProtKB: A0A4X1U7U7 (UniProtKB/TrEMBL),   A0A287B3B5 (UniProtKB/TrEMBL),   A0A8D1LJM6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000029129   ⟸   ENSSSCT00000034662
RefSeq Acc Id: ENSSSCP00000050589   ⟸   ENSSSCT00000055651
RefSeq Acc Id: ENSSSCP00000012713   ⟸   ENSSSCT00000013057
Protein Domains
Ig-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000011933 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015016100 UniProtKB/TrEMBL
  ENSSSCG00025065687 UniProtKB/TrEMBL
  ENSSSCG00030074802 UniProtKB/TrEMBL
  ENSSSCG00035021063 UniProtKB/TrEMBL
  ENSSSCG00040064383 UniProtKB/TrEMBL
  ENSSSCG00045015869 UniProtKB/TrEMBL
  ENSSSCG00050016385 UniProtKB/TrEMBL
  ENSSSCG00055001928 UniProtKB/TrEMBL
  ENSSSCG00060028898 UniProtKB/TrEMBL
  ENSSSCG00065031737 UniProtKB/TrEMBL
  ENSSSCG00070014778 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000034662.4 UniProtKB/TrEMBL
  ENSSSCT00000055651 ENTREZGENE
  ENSSSCT00000055651.3 UniProtKB/TrEMBL
  ENSSSCT00015021374.1 UniProtKB/TrEMBL
  ENSSSCT00025090560.1 UniProtKB/TrEMBL
  ENSSSCT00025090761.1 UniProtKB/TrEMBL
  ENSSSCT00025090900.1 UniProtKB/TrEMBL
  ENSSSCT00030105102.1 UniProtKB/TrEMBL
  ENSSSCT00030105107.1 UniProtKB/TrEMBL
  ENSSSCT00030105119.1 UniProtKB/TrEMBL
  ENSSSCT00030105130.1 UniProtKB/TrEMBL
  ENSSSCT00035027458.1 UniProtKB/TrEMBL
  ENSSSCT00035027470.1 UniProtKB/TrEMBL
  ENSSSCT00035027477.1 UniProtKB/TrEMBL
  ENSSSCT00040088465.1 UniProtKB/TrEMBL
  ENSSSCT00040088590.1 UniProtKB/TrEMBL
  ENSSSCT00045027112.1 UniProtKB/TrEMBL
  ENSSSCT00045027177.1 UniProtKB/TrEMBL
  ENSSSCT00045027252.1 UniProtKB/TrEMBL
  ENSSSCT00050022407.1 UniProtKB/TrEMBL
  ENSSSCT00050022422.1 UniProtKB/TrEMBL
  ENSSSCT00055003661.1 UniProtKB/TrEMBL
  ENSSSCT00055003686.1 UniProtKB/TrEMBL
  ENSSSCT00060039067.1 UniProtKB/TrEMBL
  ENSSSCT00065042997.1 UniProtKB/TrEMBL
  ENSSSCT00065043014.1 UniProtKB/TrEMBL
  ENSSSCT00065043025.1 UniProtKB/TrEMBL
  ENSSSCT00070029020.1 UniProtKB/TrEMBL
  ENSSSCT00070029027.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro CD80_C2-set UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_V-set UniProtKB/TrEMBL
  IgC1_2_Nectin-3-4-like UniProtKB/TrEMBL
  Nectin-3 UniProtKB/TrEMBL
NCBI Gene NECTIN3 ENTREZGENE
PANTHER NECTIN-RELATED UniProtKB/TrEMBL
  PTHR23277:SF12 UniProtKB/TrEMBL
Pfam C2-set_2 UniProtKB/TrEMBL
  V-set UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/TrEMBL
SMART SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
UniProt A0A287B3B5 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1U7U7 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1U8F1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0YAS4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0Z4V2_PIG UniProtKB/TrEMBL
  A0A8D1LJM6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D2C4M6_PIG UniProtKB/TrEMBL
  K7GMN4_PIG UniProtKB/TrEMBL
VGNC ID VGNC:90663 ENTREZGENE