Symbol:
Actbl2
Name:
actin, beta-like 2
RGD ID:
1309504
Description:
Predicted to enable protein kinase binding activity. Predicted to be a structural constituent of postsynaptic actin cytoskeleton. Predicted to be involved in axonogenesis and cell motility. Predicted to be part of NuA4 histone acetyltransferase complex. Predicted to be active in several cellular components, including actin filament; axon; and glutamatergic synapse. Orthologous to human ACTBL2 (actin beta like 2); INTERACTS WITH aconitine; alpha-Zearalanol; bisphenol A.
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Previously known as:
beta-actin-like protein 2; LOC294732; RGD1309504; similar to cytoplasmic beta-actin
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
ACTBL2 (actin beta like 2) HGNC
Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):
Actbl2 (actin, beta-like 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Actbl2 (actin beta like 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
ACTBL2 (actin beta like 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
ACTBL2 (actin beta like 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Actbl2 (actin beta like 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
ACTBL2 (actin beta like 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
ACTBL2 (actin beta like 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Actbl2 (actin beta like 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Rattus rattus (black rat):
Actbl2 (actin beta like 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Other homologs 2
Homo sapiens (human):
ACTB (actin beta) HGNC
OrthoDB
Homo sapiens (human):
ACTG1 (actin gamma 1) HGNC
OrthoDB
Alliance orthologs 3
Mus musculus (house mouse):
Actbl2 (actin, beta-like 2)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Homo sapiens (human):
ACTBL2 (actin beta like 2)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):
ACT1
Alliance
DIOPT (Hieranoid|InParanoid|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):
ACT1
Alliance
DIOPT (Hieranoid|InParanoid|OrthoFinder|OrthoInspector|PhylomeDB|SonicParanoid)
Drosophila melanogaster (fruit fly):
Act57B
Alliance
DIOPT (Ensembl Compara|PhylomeDB|SonicParanoid)
Drosophila melanogaster (fruit fly):
Act5C
Alliance
DIOPT (PANTHER|PhylomeDB|SonicParanoid)
Drosophila melanogaster (fruit fly):
Act79B
Alliance
DIOPT (Ensembl Compara|PhylomeDB|SonicParanoid)
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 2 44,591,391 - 44,594,138 (+) NCBI GRCr8 GRCr8 GRCr8 GRCr8 Ensembl 2 44,591,391 - 44,594,138 (+) Ensembl GRCr8 mRatBN7.2 2 42,858,020 - 42,860,767 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 2 42,858,020 - 42,860,767 (+) Ensembl mRatBN7.2 UTH_Rnor_SHR_Utx 2 49,977,431 - 49,980,178 (+) NCBI UTH_Rnor_SHR_Utx UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 2 48,035,889 - 48,038,636 (+) NCBI UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 2 42,887,407 - 42,890,154 (+) NCBI UTH_Rnor_WKY_Bbb_1.0 UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 2 42,829,413 - 42,832,160 (+) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 2 42,829,413 - 42,832,160 (+) Ensembl rn6 Rnor6.0 Rnor_5.0 2 61,878,230 - 61,880,977 (+) NCBI Rnor_5.0 Rnor_5.0 rn5 RGSC_v3.4 2 42,585,717 - 42,588,464 (+) NCBI RGSC_v3.4 RGSC_v3.4 rn4 Celera 2 38,649,115 - 38,651,862 (+) NCBI Celera RGSC_v3.1 2 42,506,171 - 42,507,348 (+) NCBI Cytogenetic Map 2 q14 NCBI
JBrowse:
Only show annotations with direct experimental evidence (0 objects hidden)
Actbl2 Rat (-)-epigallocatechin 3-gallate increases expression ISO ACTBL2 (Homo sapiens) 6480464 epigallocatechin gallate results in increased expression of ACTBL2 protein CTD PMID:31195006 Actbl2 Rat 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene multiple interactions ISO Actbl2 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Actbl2 Rat 17beta-estradiol affects expression ISO ACTBL2 (Homo sapiens) 6480464 Estradiol affects the expression of ACTBL2 mRNA CTD PMID:22574217 Actbl2 Rat 17beta-estradiol multiple interactions ISO ACTBL2 (Homo sapiens) 6480464 [Estradiol co-treated with TGFB1 protein] results in increased expression of ACTBL2 mRNA CTD PMID:30165855 Actbl2 Rat 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Actbl2 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Actbl2 Rat 2,2',4,4'-Tetrabromodiphenyl ether decreases expression ISO ACTBL2 (Homo sapiens) 6480464 2,2',4,4'-tetrabromodiphenyl ether results in decreased expression of ACTBL2 protein CTD PMID:31675489 Actbl2 Rat 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO Actbl2 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Actbl2 Rat 2,4,4'-trichlorobiphenyl multiple interactions ISO Actbl2 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Actbl2 Rat 2,4,6-tribromophenol decreases expression ISO ACTBL2 (Homo sapiens) 6480464 2,4,6-tribromophenol results in decreased expression of ACTBL2 mRNA CTD PMID:31675489 Actbl2 Rat 2,6-dimethoxyphenol multiple interactions ISO ACTBL2 (Homo sapiens) 6480464 [Furaldehyde co-treated with pyrogallol 1,3-dimethyl ether] results in increased expression of ACTBL2 protein; [pyrogallol 1,3-dimethyl more ... CTD PMID:38598786 Actbl2 Rat 2-hydroxypropanoic acid decreases expression ISO ACTBL2 (Homo sapiens) 6480464 Lactic Acid results in decreased expression of ACTBL2 mRNA CTD PMID:30851411 Actbl2 Rat 3,3',5,5'-tetrabromobisphenol A decreases expression ISO ACTBL2 (Homo sapiens) 6480464 tetrabromobisphenol A results in decreased expression of ACTBL2 protein CTD PMID:31675489 Actbl2 Rat aconitine increases expression EXP 6480464 Aconitine results in increased expression of ACTBL2 protein CTD PMID:33236894 Actbl2 Rat alpha-Zearalanol decreases expression EXP 6480464 Zeranol results in decreased expression of ACTBL2 mRNA CTD PMID:35163327 Actbl2 Rat alpha-Zearalanol multiple interactions EXP 6480464 [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of ACTBL2 mRNA CTD PMID:35163327 Actbl2 Rat arsenite(3-) decreases expression ISO Actbl2 (Mus musculus) 6480464 arsenite results in decreased expression of ACTBL2 protein CTD PMID:37955338 Actbl2 Rat benzatropine increases expression ISO ACTBL2 (Homo sapiens) 6480464 Benztropine results in increased expression of ACTBL2 protein CTD PMID:34122009 Actbl2 Rat benzo[a]pyrene decreases methylation ISO ACTBL2 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased methylation of ACTBL2 promoter CTD PMID:27901495 Actbl2 Rat benzo[a]pyrene increases expression ISO ACTBL2 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased expression of ACTBL2 mRNA CTD PMID:32234424 Actbl2 Rat benzo[a]pyrene decreases methylation ISO Actbl2 (Mus musculus) 6480464 Benzo(a)pyrene results in decreased methylation of ACTBL2 exon CTD PMID:27901495 Actbl2 Rat bis(2-ethylhexyl) phthalate increases expression ISO ACTBL2 (Homo sapiens) 6480464 Diethylhexyl Phthalate results in increased expression of ACTBL2 mRNA CTD PMID:31163220 Actbl2 Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of ACTBL2 mRNA; bisphenol A results in decreased expression more ... CTD PMID:25181051|PMID:32145629 Actbl2 Rat bisphenol A decreases expression ISO ACTBL2 (Homo sapiens) 6480464 bisphenol A results in decreased expression of ACTBL2 protein CTD PMID:31675489 Actbl2 Rat bisphenol A multiple interactions ISO ACTBL2 (Homo sapiens) 6480464 [[ginger extract results in increased abundance of Oils, Volatile] which co-treated with bisphenol A] affects more ... CTD PMID:31629898|PMID:33376534 Actbl2 Rat bisphenol A increases methylation ISO Actbl2 (Mus musculus) 6480464 bisphenol A results in increased methylation of ACTBL2 promoter CTD PMID:27312807 Actbl2 Rat bisphenol A decreases methylation ISO Actbl2 (Mus musculus) 6480464 bisphenol A results in decreased methylation of ACTBL2 promoter CTD PMID:27312807 Actbl2 Rat cadmium dichloride increases expression ISO ACTBL2 (Homo sapiens) 6480464 Cadmium Chloride results in increased expression of ACTBL2 protein CTD PMID:24527689 Actbl2 Rat caffeine increases expression ISO ACTBL2 (Homo sapiens) 6480464 Caffeine results in increased expression of ACTBL2 protein CTD PMID:31195006 Actbl2 Rat clozapine increases expression ISO ACTBL2 (Homo sapiens) 6480464 Clozapine results in increased expression of ACTBL2 protein CTD PMID:34122009 Actbl2 Rat DDE increases expression ISO ACTBL2 (Homo sapiens) 6480464 Dichlorodiphenyl Dichloroethylene results in increased expression of ACTBL2 mRNA CTD PMID:38568856 Actbl2 Rat decabromodiphenyl ether decreases expression ISO ACTBL2 (Homo sapiens) 6480464 decabromobiphenyl ether results in decreased expression of ACTBL2 protein CTD PMID:31675489 Actbl2 Rat deoxynivalenol decreases phosphorylation ISO Actbl2 (Mus musculus) 6480464 deoxynivalenol results in decreased phosphorylation of ACTBL2 protein CTD PMID:23352502 Actbl2 Rat diquat decreases expression ISO Actbl2 (Mus musculus) 6480464 Diquat results in decreased expression of ACTBL2 protein CTD PMID:36851058 Actbl2 Rat dopamine decreases expression ISO ACTBL2 (Homo sapiens) 6480464 Dopamine results in decreased expression of ACTBL2 protein CTD PMID:24675778 Actbl2 Rat furfural multiple interactions ISO ACTBL2 (Homo sapiens) 6480464 [Furaldehyde co-treated with pyrogallol 1,3-dimethyl ether] results in increased expression of ACTBL2 protein; [pyrogallol 1,3-dimethyl more ... CTD PMID:38598786 Actbl2 Rat genistein decreases expression ISO ACTBL2 (Homo sapiens) 6480464 Genistein results in decreased expression of ACTBL2 protein CTD PMID:20884965 Actbl2 Rat genistein multiple interactions ISO ACTBL2 (Homo sapiens) 6480464 ESR1 promotes the reaction [Genistein results in decreased expression of ACTBL2 protein] CTD PMID:20884965 Actbl2 Rat ivermectin decreases expression ISO ACTBL2 (Homo sapiens) 6480464 Ivermectin results in decreased expression of ACTBL2 protein CTD PMID:32959892 Actbl2 Rat methylisothiazolinone increases expression ISO ACTBL2 (Homo sapiens) 6480464 2-methyl-4-isothiazolin-3-one results in increased expression of ACTBL2 mRNA CTD PMID:31629900 Actbl2 Rat N-methyl-4-phenylpyridinium decreases expression ISO ACTBL2 (Homo sapiens) 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of ACTBL2 protein CTD PMID:24675778 Actbl2 Rat okadaic acid increases expression ISO ACTBL2 (Homo sapiens) 6480464 Okadaic Acid results in increased expression of ACTBL2 mRNA CTD PMID:38832940 Actbl2 Rat PCB138 multiple interactions ISO Actbl2 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Actbl2 Rat perfluorooctanoic acid multiple interactions EXP 6480464 [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of ACTBL2 mRNA CTD PMID:35163327 Actbl2 Rat phenol red multiple interactions ISO ACTBL2 (Homo sapiens) 6480464 [Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of ACTBL2 protein CTD PMID:31629898 Actbl2 Rat rac-lactic acid decreases expression ISO ACTBL2 (Homo sapiens) 6480464 Lactic Acid results in decreased expression of ACTBL2 mRNA CTD PMID:30851411 Actbl2 Rat resveratrol multiple interactions ISO ACTBL2 (Homo sapiens) 6480464 [Plant Extracts co-treated with Resveratrol] results in decreased expression of ACTBL2 mRNA CTD PMID:23557933 Actbl2 Rat sodium arsenite decreases expression ISO ACTBL2 (Homo sapiens) 6480464 sodium arsenite results in decreased expression of ACTBL2 mRNA CTD PMID:34032870|PMID:39719251 Actbl2 Rat sodium arsenite increases expression ISO ACTBL2 (Homo sapiens) 6480464 sodium arsenite results in increased expression of ACTBL2 protein CTD PMID:38228842 Actbl2 Rat sodium chloride multiple interactions ISO ACTBL2 (Homo sapiens) 6480464 [Sodium Chloride co-treated with Furaldehyde] results in increased expression of and affects the localization of more ... CTD PMID:38598786 Actbl2 Rat sodium fluoride decreases expression ISO Actbl2 (Mus musculus) 6480464 Sodium Fluoride results in decreased expression of ACTBL2 protein CTD PMID:27548804 Actbl2 Rat sotorasib multiple interactions ISO ACTBL2 (Homo sapiens) 6480464 [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ACTBL2 mRNA CTD PMID:36139627 Actbl2 Rat trametinib multiple interactions ISO ACTBL2 (Homo sapiens) 6480464 [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ACTBL2 mRNA CTD PMID:36139627 Actbl2 Rat zoledronic acid increases expression ISO ACTBL2 (Homo sapiens) 6480464 zoledronic acid results in increased expression of ACTBL2 mRNA CTD PMID:24714768 
