Lrrc49 (leucine rich repeat containing 49) - Rat Genome Database

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Pathways
Gene: Lrrc49 (leucine rich repeat containing 49) Rattus norvegicus
Analyze
Symbol: Lrrc49
Name: leucine rich repeat containing 49
RGD ID: 1309466
Description: Predicted to act upstream of or within cilium disassembly and microtubule polymerization. Predicted to be located in centriolar satellite. Orthologous to human LRRC49 (leucine rich repeat containing 49); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: leucine-rich repeat-containing protein 49; LOC300763; RGD1309466; similar to hypothetical protein FLJ20156
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8869,948,962 - 70,056,579 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl869,948,972 - 70,079,636 (-)EnsemblGRCr8
mRatBN7.2861,053,264 - 61,160,695 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl861,053,267 - 61,160,850 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx866,561,249 - 66,668,708 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0864,834,189 - 64,941,267 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0862,703,669 - 62,811,138 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0865,481,584 - 65,587,687 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl865,481,592 - 65,587,658 (-)Ensemblrn6Rnor6.0
Rnor_5.0865,233,813 - 65,339,662 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4864,524,550 - 64,631,904 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera860,480,044 - 60,587,218 (-)NCBICelera
RGSC_v3.1864,543,611 - 64,650,971 (-)NCBI
Cytogenetic Map8q24NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932  


Genomics

Comparative Map Data
Lrrc49
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8869,948,962 - 70,056,579 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl869,948,972 - 70,079,636 (-)EnsemblGRCr8
mRatBN7.2861,053,264 - 61,160,695 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl861,053,267 - 61,160,850 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx866,561,249 - 66,668,708 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0864,834,189 - 64,941,267 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0862,703,669 - 62,811,138 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0865,481,584 - 65,587,687 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl865,481,592 - 65,587,658 (-)Ensemblrn6Rnor6.0
Rnor_5.0865,233,813 - 65,339,662 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4864,524,550 - 64,631,904 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera860,480,044 - 60,587,218 (-)NCBICelera
RGSC_v3.1864,543,611 - 64,650,971 (-)NCBI
Cytogenetic Map8q24NCBI
LRRC49
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381570,853,378 - 71,053,658 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1570,853,239 - 71,053,658 (+)Ensemblhg38GRCh38
GRCh371571,145,717 - 71,345,997 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361568,972,041 - 69,129,490 (+)NCBIBuild 36Build 36hg18NCBI36
Celera1548,075,878 - 48,233,321 (+)NCBICelera
Cytogenetic Map15q23NCBI
HuRef1548,020,472 - 48,177,963 (+)NCBIHuRef
CHM1_11571,303,192 - 71,460,675 (+)NCBICHM1_1
T2T-CHM13v2.01568,676,342 - 68,876,951 (+)NCBIT2T-CHM13v2.0
Lrrc49
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39960,494,507 - 60,595,460 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl960,476,142 - 60,595,441 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38960,587,224 - 60,688,167 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl960,568,859 - 60,688,158 (-)Ensemblmm10GRCm38
MGSCv37960,435,036 - 60,535,941 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36960,385,246 - 60,485,917 (-)NCBIMGSCv36mm8
Celera957,812,803 - 57,913,421 (-)NCBICelera
Cytogenetic Map9BNCBI
cM Map932.75NCBI
Lrrc49
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554505,903,266 - 6,030,279 (-)Ensembl
ChiLan1.0NW_0049554505,903,345 - 6,030,279 (-)NCBIChiLan1.0ChiLan1.0
LRRC49
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21660,155,994 - 60,316,144 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11564,319,908 - 64,479,628 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01549,841,934 - 50,023,736 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11568,608,412 - 68,769,334 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1568,589,175 - 68,769,334 (+)EnsemblpanPan2panpan1.1
LRRC49
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13034,580,906 - 34,737,181 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3034,581,241 - 34,737,009 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3034,515,159 - 34,673,673 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03034,781,934 - 34,938,531 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3034,782,217 - 34,938,848 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13034,728,801 - 34,893,909 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03034,766,753 - 34,921,966 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03035,018,625 - 35,177,587 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Lrrc49
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640112,568,323 - 112,729,798 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647130,416,174 - 30,577,874 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647130,416,179 - 30,578,312 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LRRC49
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1168,544,421 - 168,700,891 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11168,553,361 - 168,711,739 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21186,834,369 - 186,981,844 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LRRC49
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12612,405,249 - 12,568,597 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2612,405,721 - 12,567,987 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666048128,921,019 - 129,151,558 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lrrc49
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247812,848,502 - 2,990,738 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247812,848,567 - 3,007,102 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Lrrc49
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1854,881,283 - 54,987,753 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Lrrc49
484 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:88
Count of miRNA genes:68
Interacting mature miRNAs:80
Transcripts:ENSRNOT00000016491
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298065Scl16Serum cholesterol level QTL 163.8blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)83975280384752803Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)849849908118871671Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)839106363103375781Rat
1298079Activ2Activity QTL 29.50.000001voluntary movement trait (VT:0003491)rearing measurement (CMO:0001515)85076395195763951Rat
11556286Cm81Cardiac mass QTL 810.01heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)83910625884106258Rat
70161Bp62Blood pressure QTL 622.90.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)85158969999045312Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)839106363103375781Rat
61464Niddm11Non-insulin dependent diabetes mellitus QTL 113.10.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)84447792689477926Rat
4889938Bss89Bone structure and strength QTL 893.8tibia size trait (VT:0100001)tibia cortical bone volume (CMO:0001725)85899169791341052Rat
1578755Pur5Proteinuria QTL 53.30.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)839106258103375958Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)861019838121662124Rat
2313088Bss75Bone structure and strength QTL 753.10.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)83910625891341052Rat
8662823Vetf5Vascular elastic tissue fragility QTL 51.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)863404444108404444Rat
1358896Bp262Blood pressure QTL 2622.89arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)835464071107982864Rat
731182Uae24Urinary albumin excretion QTL 246.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)84754141992541419Rat
61353Bp35Blood pressure QTL 350.001arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)83910625884106258Rat
631842Inf1Infertility severity QTL 14.10.001seminal gland mass (VT:0010524)seminal vesicle wet weight (CMO:0001603)83154366176543661Rat
1331769Rf39Renal function QTL 393.871urine output (VT:0003620)timed urine volume (CMO:0000260)850763951107970527Rat
1359033Bp273Blood pressure QTL 273arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83910625884106258Rat
1358906Bp253Blood pressure QTL 25340.0004arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)84961020494610204Rat
61358Bp39Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)84444783789447837Rat
1358907Cm40Cardiac mass QTL 401.89heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)835464071107982864Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)855428333127966348Rat
2316950Scl66Serum cholesterol level QTL 664.1blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)839106363114525825Rat
1582254Kidm31Kidney mass QTL 313kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)84924517894245178Rat
724540Uae8Urinary albumin excretion QTL 85urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)839106258103375958Rat
10402857Bp380Blood pressure QTL 3800.95arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)862848139107848139Rat
1358892Kidm26Kidney mass QTL 263.69kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)835464071107982864Rat
1582243Bw66Body weight QTL 663.40.0048body mass (VT:0001259)body weight (CMO:0000012)84924517894245178Rat
5684973Bss100Bone structure and strength QTL 1004.7tibia area (VT:1000281)tibia area measurement (CMO:0001382)85899169791341052Rat
61373Mcs4Mammary carcinoma susceptibility QTL 41.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)84447504389475043Rat
1300177Cm2Cardiac mass QTL 23.65heart mass (VT:0007028)heart weight (CMO:0000017)863141536109261840Rat
2313057Bss76Bone structure and strength QTL 7630.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)83910625891341052Rat
12879878Bw183Body weight QTL 1830.001body mass (VT:0001259)body weight (CMO:0000012)862848139107848139Rat
1549908Neudeg1Neurodegradation QTL 15.50nervous system integrity trait (VT:0010566)logarithm of the ratio of the lesioned side motor neuron count to contralateral side motor neuron count (CMO:0001986)858337123103337123Rat
12879879Cm99Cardiac mass QTL 990.001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)862848139107848139Rat
1331804Cm30Cardiac mass QTL 303.77443heart mass (VT:0007028)heart wet weight (CMO:0000069)862970527107970527Rat
2313067Bss77Bone structure and strength QTL 773.10.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)83910625891341052Rat
12879880Cm100Cardiac mass QTL 1000.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)862848139107848139Rat
12879881Cm101Cardiac mass QTL 1010.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)862848139107848139Rat
12879882Am8Aortic mass QTL 80.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)862848139107848139Rat
12879883Kidm65Kidney mass QTL 650.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)862848139107848139Rat
71120Niddm21Non-insulin dependent diabetes mellitus QTL 213.73blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)866992095111992095Rat
1358912Bw51Body weight QTL 512.95body mass (VT:0001259)body weight (CMO:0000012)860248093105248093Rat
2313086Bss60Bone structure and strength QTL 604.10.0001tibia length (VT:0004357)tibia length (CMO:0000450)85899169791341052Rat
2293697Bmd39Bone mineral density QTL 39femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)862848139107848139Rat
631648Stl5Serum triglyceride level QTL 540.0003blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)83546407171842899Rat
1331837Bw23Body weight QTL 234.190.00007body mass (VT:0001259)body weight (CMO:0000012)855428416107963099Rat
1331838Niddm61Non-insulin dependent diabetes mellitus QTL 613.530.0004blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)862963099107963099Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)870041301121080908Rat
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)868690349119799881Rat
2313046Bss78Bone structure and strength QTL 783.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)83910625891341052Rat
631664Hcar3Hepatocarcinoma resistance QTL 32.90.0005liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)862982864107982864Rat
2301402Bp316Blood pressure QTL 3160.005arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)862848139107848139Rat

Markers in Region
D8Rat184  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8870,041,409 - 70,041,571 (+)Marker Load Pipeline
mRatBN7.2861,145,771 - 61,145,933 (+)MAPPERmRatBN7.2
Rnor_6.0865,572,904 - 65,573,065NCBIRnor6.0
Rnor_5.0865,325,139 - 65,325,300UniSTSRnor5.0
RGSC_v3.4864,617,023 - 64,617,185RGDRGSC3.4
RGSC_v3.4864,617,024 - 64,617,185UniSTSRGSC3.4
Celera860,572,500 - 60,572,661UniSTS
RGSC_v3.1864,636,077 - 64,636,239RGD
SHRSP x BN Map843.6499UniSTS
SHRSP x BN Map843.6499RGD
Cytogenetic Map8q24UniSTS
D8Rat185  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8869,997,375 - 69,997,602 (+)Marker Load Pipeline
mRatBN7.2861,101,680 - 61,101,909 (+)MAPPERmRatBN7.2
Rnor_6.0865,528,892 - 65,529,118NCBIRnor6.0
Rnor_5.0865,281,152 - 65,281,378UniSTSRnor5.0
RGSC_v3.4864,572,921 - 64,573,148RGDRGSC3.4
RGSC_v3.4864,572,922 - 64,573,148UniSTSRGSC3.4
Celera860,528,540 - 60,528,766UniSTS
RGSC_v3.1864,591,975 - 64,592,202RGD
SHRSP x BN Map843.6499UniSTS
SHRSP x BN Map843.6499RGD
Cytogenetic Map8q24UniSTS
RH133570  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2861,161,189 - 61,161,372 (+)MAPPERmRatBN7.2
Rnor_6.0865,587,922 - 65,588,104NCBIRnor6.0
Rnor_5.0865,340,157 - 65,340,339UniSTSRnor5.0
RGSC_v3.4864,632,399 - 64,632,581UniSTSRGSC3.4
Celera860,587,713 - 60,587,895UniSTS
Cytogenetic Map8q24UniSTS
RH133846  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2861,053,443 - 61,053,632 (+)MAPPERmRatBN7.2
Rnor_6.0865,481,764 - 65,481,952NCBIRnor6.0
Rnor_5.0865,233,993 - 65,234,181UniSTSRnor5.0
RGSC_v3.4864,524,730 - 64,524,918UniSTSRGSC3.4
Celera860,480,224 - 60,480,412UniSTS
RH 3.4 Map8723.8UniSTS
Cytogenetic Map8q24UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 80 59 6 344 180 11 143 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001134469 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001436458 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001436459 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001436460 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_199174 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006243202 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006243204 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017595562 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265143 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265144 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265145 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265146 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265147 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265148 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265149 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265150 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265151 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC160848 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473975 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ211943 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000016491   ⟹   ENSRNOP00000016491
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl869,948,972 - 70,056,333 (-)Ensembl
mRatBN7.2 Ensembl861,053,272 - 61,160,695 (-)Ensembl
Rnor_6.0 Ensembl865,481,592 - 65,587,427 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000091982   ⟹   ENSRNOP00000074741
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl869,948,972 - 70,056,080 (-)Ensembl
mRatBN7.2 Ensembl861,053,272 - 61,160,243 (-)Ensembl
Rnor_6.0 Ensembl865,481,613 - 65,587,658 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000109644   ⟹   ENSRNOP00000097055
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl869,948,972 - 70,056,080 (-)Ensembl
mRatBN7.2 Ensembl861,053,267 - 61,160,850 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000119955   ⟹   ENSRNOP00000077361
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl869,948,972 - 70,079,636 (-)Ensembl
mRatBN7.2 Ensembl861,053,272 - 61,160,695 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000132362   ⟹   ENSRNOP00000105989
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl869,948,972 - 70,056,333 (-)Ensembl
RefSeq Acc Id: NM_001134469   ⟹   NP_001127941
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8869,948,964 - 70,056,333 (-)NCBI
mRatBN7.2861,053,264 - 61,160,695 (-)NCBI
Rnor_6.0865,481,584 - 65,587,427 (-)NCBI
Rnor_5.0865,233,813 - 65,339,662 (-)NCBI
RGSC_v3.4864,524,550 - 64,631,904 (-)RGD
Celera860,480,044 - 60,587,218 (-)RGD
Sequence:
RefSeq Acc Id: XM_063265143   ⟹   XP_063121213
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8869,948,962 - 70,056,382 (-)NCBI
RefSeq Acc Id: XM_063265144   ⟹   XP_063121214
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8869,948,962 - 70,055,927 (-)NCBI
RefSeq Acc Id: XM_063265145   ⟹   XP_063121215
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8869,948,962 - 70,056,383 (-)NCBI
RefSeq Acc Id: XM_063265146   ⟹   XP_063121216
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8869,948,962 - 70,055,951 (-)NCBI
RefSeq Acc Id: XM_063265147   ⟹   XP_063121217
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8869,948,962 - 70,056,383 (-)NCBI
RefSeq Acc Id: XM_063265148   ⟹   XP_063121218
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8869,948,962 - 70,055,915 (-)NCBI
RefSeq Acc Id: XM_063265149   ⟹   XP_063121219
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8869,948,962 - 70,056,579 (-)NCBI
RefSeq Acc Id: XM_063265150   ⟹   XP_063121220
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8869,948,962 - 70,055,633 (-)NCBI
RefSeq Acc Id: XM_063265151   ⟹   XP_063121221
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8869,948,962 - 70,053,474 (-)NCBI
RefSeq Acc Id: XM_063265152   ⟹   XP_063121222
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8869,948,963 - 70,037,424 (-)NCBI
RefSeq Acc Id: NP_001127941   ⟸   NM_001134469
- UniProtKB: B1H239 (UniProtKB/TrEMBL),   A0A8I5ZJG3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000016491   ⟸   ENSRNOT00000016491
Ensembl Acc Id: ENSRNOP00000074741   ⟸   ENSRNOT00000091982
Ensembl Acc Id: ENSRNOP00000097055   ⟸   ENSRNOT00000109644
Ensembl Acc Id: ENSRNOP00000077361   ⟸   ENSRNOT00000119955
RefSeq Acc Id: XP_063121219   ⟸   XM_063265149
- Peptide Label: isoform X7
- UniProtKB: A0A8I5ZJG3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063121217   ⟸   XM_063265147
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063121215   ⟸   XM_063265145
- Peptide Label: isoform X3
- UniProtKB: A0A8I5ZJG3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063121213   ⟸   XM_063265143
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063121216   ⟸   XM_063265146
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063121214   ⟸   XM_063265144
- Peptide Label: isoform X2
- UniProtKB: A0A0G2K8U5 (UniProtKB/TrEMBL),   A0A8I5ZJG3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063121218   ⟸   XM_063265148
- Peptide Label: isoform X6
- UniProtKB: A0A8I5ZJG3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063121220   ⟸   XM_063265150
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063121221   ⟸   XM_063265151
- Peptide Label: isoform X8
- UniProtKB: A0A8I6AQS1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063121222   ⟸   XM_063265152
- Peptide Label: isoform X8
- UniProtKB: A0A8I6AQS1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000105989   ⟸   ENSRNOT00000132362

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K8U5-F1-model_v2 AlphaFold A0A0G2K8U5 1-752 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696050
Promoter ID:EPDNEW_R6569
Type:multiple initiation site
Name:Lrrc49_1
Description:leucine rich repeat containing 49
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0865,587,575 - 65,587,635EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309466 AgrOrtholog
BioCyc Gene G2FUF-30214 BioCyc
Ensembl Genes ENSRNOG00000012015 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000016491 ENTREZGENE
  ENSRNOT00000016491.6 UniProtKB/TrEMBL
  ENSRNOT00000091982 ENTREZGENE
  ENSRNOT00000091982.3 UniProtKB/TrEMBL
  ENSRNOT00000109644 ENTREZGENE
  ENSRNOT00000109644.2 UniProtKB/TrEMBL
  ENSRNOT00000119955 ENTREZGENE
  ENSRNOT00000119955.2 UniProtKB/TrEMBL
  ENSRNOT00000132362 ENTREZGENE
  ENSRNOT00000132362.1 UniProtKB/TrEMBL
Gene3D-CATH 3.80.10.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:8363379 IMAGE-MGC_LOAD
InterPro Cilia_flagella_integrity UniProtKB/TrEMBL
  L_dom-like UniProtKB/TrEMBL
  Leu-rich_rpt UniProtKB/TrEMBL
  Leu-rich_rpt_4 UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/TrEMBL
KEGG Report rno:300763 UniProtKB/TrEMBL
MGC_CLONE MGC:187588 IMAGE-MGC_LOAD
NCBI Gene 300763 ENTREZGENE
PANTHER LEUCINE-RICH REPEAT-CONTAINING PROTEIN 49 UniProtKB/TrEMBL
  PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED UniProtKB/TrEMBL
Pfam LRR_4 UniProtKB/TrEMBL
  LRR_9 UniProtKB/TrEMBL
PhenoGen Lrrc49 PhenoGen
PROSITE LRR UniProtKB/TrEMBL
RatGTEx ENSRNOG00000012015 RatGTEx
SMART LRR_SD22 UniProtKB/TrEMBL
  LRR_TYP UniProtKB/TrEMBL
Superfamily-SCOP L domain-like UniProtKB/TrEMBL
  Outer arm dynein light chain 1 UniProtKB/TrEMBL
UniProt A0A0G2K8U5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZJG3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AQS1 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LQB1_RAT UniProtKB/TrEMBL
  B1H239 ENTREZGENE, UniProtKB/TrEMBL
  F7FG58 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Lrrc49  leucine rich repeat containing 49   Lrrc49_predicted  leucine rich repeat containing 49 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Lrrc49_predicted  leucine rich repeat containing 49 (predicted)  RGD1309466_predicted  similar to hypothetical protein FLJ20156 (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-20 RGD1309466_predicted  similar to hypothetical protein FLJ20156 (predicted)  LOC300763_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC300763_predicted  similar to hypothetical protein FLJ20156 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL