Exo1 (exonuclease 1) - Rat Genome Database

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Gene: Exo1 (exonuclease 1) Rattus norvegicus
Analyze
Symbol: Exo1
Name: exonuclease 1
RGD ID: 1309465
Description: Predicted to enable DNA binding activity; DNA nuclease activity; and chromatin binding activity. Predicted to be involved in DNA recombination; DNA strand resection involved in replication fork processing; and mismatch repair. Predicted to act upstream of or within humoral immune response mediated by circulating immunoglobulin; isotype switching; and somatic hypermutation of immunoglobulin genes. Predicted to be located in nuclear body and plasma membrane. Predicted to be active in nucleus. Orthologous to human EXO1 (exonuclease 1); PARTICIPATES IN homologous recombination pathway of double-strand break repair; mismatch repair pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC305000
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81390,341,947 - 90,366,861 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1390,342,018 - 90,366,861 (+)EnsemblGRCr8
mRatBN7.21387,809,725 - 87,834,654 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1387,809,810 - 87,834,654 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1390,302,568 - 90,327,416 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01391,702,852 - 91,727,700 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01388,880,238 - 88,905,108 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01393,936,989 - 93,962,749 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1393,939,022 - 93,960,342 (+)Ensemblrn6Rnor6.0
Rnor_5.01398,401,025 - 98,427,400 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41391,619,024 - 91,644,366 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1387,401,444 - 87,426,359 (+)NCBICelera
RGSC_v3.11391,809,937 - 91,831,012 (+)NCBI
Cytogenetic Map13q24NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-dexrazoxane  (ISO)
(-)-demecolcine  (ISO)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4,4'-trichlorobiphenyl  (ISO)
2,4-diaminotoluene  (ISO)
2-methylcholine  (ISO)
2-palmitoylglycerol  (ISO)
3-methylcholanthrene  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrolein  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
amiodarone  (ISO)
atrazine  (ISO)
azathioprine  (ISO)
barium sulfate  (EXP)
belinostat  (ISO)
benzalkonium chloride  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
beta-lapachone  (ISO)
biphenyl-4-amine  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
Butylbenzyl phthalate  (ISO)
cadmium dichloride  (EXP,ISO)
calcitriol  (ISO)
cannabidiol  (ISO)
carbon nanotube  (ISO)
cefaloridine  (EXP)
ceric oxide  (EXP)
chlorpyrifos  (ISO)
choline  (ISO)
chromium(6+)  (ISO)
cisplatin  (EXP,ISO)
cobalt dichloride  (EXP,ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
coumestrol  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
desferrioxamine B  (ISO)
diallyl disulfide  (EXP)
dibutyl phthalate  (ISO)
diethyl maleate  (EXP)
dioxygen  (ISO)
doxorubicin  (EXP,ISO)
endosulfan  (ISO)
Enterolactone  (ISO)
ethyl methanesulfonate  (ISO)
flumequine  (ISO)
folic acid  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
furan  (EXP)
glyphosate  (ISO)
idarubicin  (ISO)
kenpaullone  (EXP)
L-methionine  (ISO)
Lasiocarpine  (ISO)
lead(0)  (ISO)
lucanthone  (ISO)
MeIQx  (ISO)
methyl methanesulfonate  (ISO)
miconazole  (ISO)
ochratoxin A  (EXP)
okadaic acid  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
palbociclib  (ISO)
paracetamol  (ISO)
PCB138  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
phosphoramide mustard  (EXP)
picoxystrobin  (ISO)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (ISO)
resveratrol  (EXP,ISO)
rotenone  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP,ISO)
succimer  (ISO)
tebufenpyrad  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
thapsigargin  (ISO)
thiram  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
tributylstannane  (EXP)
triclosan  (ISO)
trimellitic anhydride  (ISO)
troglitazone  (ISO)
valproic acid  (ISO)
vincristine  (ISO)
VX nerve agent  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nuclear body  (IEA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IBA,IEA,ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Regulation of homologous recombination in eukaryotes. Heyer WD, etal., Annu Rev Genet. 2010;44:113-39. doi: 10.1146/annurev-genet-051710-150955.
3. The Rat Genome Database curation tool suite: a set of optimized software tools enabling efficient acquisition, organization, and presentation of biological data. Laulederkind SJ, etal., Database (Oxford). 2011 Feb 14;2011:bar002. Print 2011.
4. Mechanisms and functions of DNA mismatch repair. Li GM Cell Res. 2008 Jan;18(1):85-98.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:9788596   PMID:10364235   PMID:10608837   PMID:11429708   PMID:11809771   PMID:11842105   PMID:14636568   PMID:14676842   PMID:14716311  


Genomics

Comparative Map Data
Exo1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81390,341,947 - 90,366,861 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1390,342,018 - 90,366,861 (+)EnsemblGRCr8
mRatBN7.21387,809,725 - 87,834,654 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1387,809,810 - 87,834,654 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1390,302,568 - 90,327,416 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01391,702,852 - 91,727,700 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01388,880,238 - 88,905,108 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01393,936,989 - 93,962,749 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1393,939,022 - 93,960,342 (+)Ensemblrn6Rnor6.0
Rnor_5.01398,401,025 - 98,427,400 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41391,619,024 - 91,644,366 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1387,401,444 - 87,426,359 (+)NCBICelera
RGSC_v3.11391,809,937 - 91,831,012 (+)NCBI
Cytogenetic Map13q24NCBI
EXO1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381241,847,986 - 241,889,939 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1241,847,967 - 241,895,148 (+)Ensemblhg38GRCh38
GRCh371242,011,506 - 242,053,241 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361240,078,158 - 240,119,671 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341238,337,575 - 238,379,088NCBI
Celera1215,267,055 - 215,308,778 (+)NCBICelera
Cytogenetic Map1q43NCBI
HuRef1212,470,280 - 212,512,011 (+)NCBIHuRef
CHM1_11243,284,062 - 243,325,806 (+)NCBICHM1_1
T2T-CHM13v2.01241,253,764 - 241,301,952 (+)NCBIT2T-CHM13v2.0
Exo1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391175,708,334 - 175,738,962 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1175,708,147 - 175,741,055 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381175,880,768 - 175,911,396 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1175,880,581 - 175,913,489 (+)Ensemblmm10GRCm38
MGSCv371177,810,909 - 177,841,527 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361177,717,473 - 177,745,968 (+)NCBIMGSCv36mm8
Celera1182,960,192 - 182,991,063 (+)NCBICelera
Cytogenetic Map1H4NCBI
cM Map181.9NCBI
Exo1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540610,245,886 - 10,275,522 (-)Ensembl
ChiLan1.0NW_00495540610,248,981 - 10,276,207 (-)NCBIChiLan1.0ChiLan1.0
EXO1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v217,257,728 - 7,299,702 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan117,480,934 - 7,522,838 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01217,410,175 - 217,451,982 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11222,389,684 - 222,431,556 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1222,389,684 - 222,431,556 (+)EnsemblpanPan2panpan1.1
EXO1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1733,237,124 - 33,268,835 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl733,237,593 - 33,268,254 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha732,715,899 - 32,747,606 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0733,063,694 - 33,095,420 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl733,064,115 - 33,094,883 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1732,898,615 - 32,930,322 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0732,921,322 - 32,953,099 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0733,172,357 - 33,204,106 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Exo1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934446,119,726 - 46,144,065 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365268,570,488 - 8,627,004 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EXO1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1015,317,581 - 15,359,839 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11015,317,555 - 15,360,593 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21017,632,191 - 17,673,665 (+)NCBISscrofa10.2Sscrofa10.2susScr3
EXO1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12578,934,337 - 78,976,346 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2578,934,459 - 78,976,219 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605581,071,662 - 81,113,887 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Exo1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462477112,215,957 - 12,230,908 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Exo1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11054,392,262 - 54,415,618 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Exo1
185 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:757
Count of miRNA genes:302
Interacting mature miRNAs:394
Transcripts:ENSRNOT00000005314
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
738027Lnnr6Liver neoplastic nodule remodeling QTL 63.3liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)1365613454109350286Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1321120177109350286Rat
7387280Uae43Urinary albumin excretion QTL 435.690.4174urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1368983334109350286Rat
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134863963493639634Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1367635937109350286Rat
1576318Schws5Schwannoma susceptibility QTL 50.0351nervous system integrity trait (VT:0010566)post-insult time to trigeminal nerve neurilemmoma formation (CMO:0002019)1364497900109350286Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1311081740103588154Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1338975045103588154Rat
8655951Rf63Renal function QTL 6312.2blood urea nitrogen amount (VT:0005265)plasma urea nitrogen level (CMO:0000586)1371610804109350286Rat
4889606Gluco63Glucose level QTL 632.860.003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1383286150109350286Rat
8655959Pur32Proteinuria QTL 328.4urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)137298450699745408Rat
1302791Stl29Serum triglyceride level QTL 293.30.0011blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)138933312992500981Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1367635937109350286Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1364375743109350286Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131103588154Rat
724564Uae11Urinary albumin excretion QTL 115.7urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)134735425894285672Rat
2293341Glom15Glomerulus QTL 159.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1367635937109350286Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 10 65 162 88 87 56 81 56 6 330 176 11 141 75 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000088204   ⟹   ENSRNOP00000073202
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1390,342,018 - 90,366,861 (+)Ensembl
mRatBN7.2 Ensembl1387,809,810 - 87,834,654 (+)Ensembl
Rnor_6.0 Ensembl1393,939,022 - 93,960,342 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000110373   ⟹   ENSRNOP00000084933
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1390,342,313 - 90,366,861 (+)Ensembl
mRatBN7.2 Ensembl1387,809,810 - 87,834,654 (+)Ensembl
RefSeq Acc Id: NM_001107198   ⟹   NP_001100668
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81390,342,018 - 90,366,861 (+)NCBI
mRatBN7.21387,809,810 - 87,834,654 (+)NCBI
Rnor_6.01393,936,989 - 93,962,749 (+)NCBI
Rnor_5.01398,401,025 - 98,427,400 (+)NCBI
RGSC_v3.41391,619,024 - 91,644,366 (+)RGD
Celera1387,401,444 - 87,426,359 (+)RGD
Sequence:
RefSeq Acc Id: XM_039090805   ⟹   XP_038946733
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81390,341,947 - 90,364,629 (+)NCBI
mRatBN7.21387,809,725 - 87,833,711 (+)NCBI
RefSeq Acc Id: XM_039090806   ⟹   XP_038946734
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81390,341,948 - 90,364,629 (+)NCBI
mRatBN7.21387,809,725 - 87,833,711 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001100668 (Get FASTA)   NCBI Sequence Viewer  
  XP_038946733 (Get FASTA)   NCBI Sequence Viewer  
  XP_038946734 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL94776 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000073202
  ENSRNOP00000073202.2
  ENSRNOP00000084933
  ENSRNOP00000084933.1
RefSeq Acc Id: NP_001100668   ⟸   NM_001107198
- Sequence:
Ensembl Acc Id: ENSRNOP00000073202   ⟸   ENSRNOT00000088204
RefSeq Acc Id: XP_038946733   ⟸   XM_039090805
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K4W8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038946734   ⟸   XM_039090806
- Peptide Label: isoform X2
- UniProtKB: A0A8I6A158 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000084933   ⟸   ENSRNOT00000110373
Protein Domains
XPG N-terminal   XPG-I

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K4W8-F1-model_v2 AlphaFold A0A0G2K4W8 1-836 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309465 AgrOrtholog
BioCyc Gene G2FUF-17216 BioCyc
Ensembl Genes ENSRNOG00000056209 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000088204 ENTREZGENE
  ENSRNOT00000088204.3 UniProtKB/TrEMBL
  ENSRNOT00000110373 ENTREZGENE
  ENSRNOT00000110373.2 UniProtKB/TrEMBL
Gene3D-CATH 5' to 3' exonuclease, C-terminal subdomain UniProtKB/TrEMBL
  5'-nuclease UniProtKB/TrEMBL
InterPro 5-3_exonuclease_C_sf UniProtKB/TrEMBL
  EXO1_H3TH UniProtKB/TrEMBL
  HhH2 UniProtKB/TrEMBL
  PIN-like_EXO1 UniProtKB/TrEMBL
  PIN_domain-like UniProtKB/TrEMBL
  XPG/Rad2 UniProtKB/TrEMBL
  XPG/RAD2_endonuclease UniProtKB/TrEMBL
  XPG_CS UniProtKB/TrEMBL
  XPG_DNA_repair_N UniProtKB/TrEMBL
KEGG Report rno:305000 UniProtKB/TrEMBL
NCBI Gene 305000 ENTREZGENE
PANTHER PTHR11081 UniProtKB/TrEMBL
  PTHR11081:SF8 UniProtKB/TrEMBL
Pfam XPG_I UniProtKB/TrEMBL
  XPG_N UniProtKB/TrEMBL
PhenoGen Exo1 PhenoGen
PRINTS XPGRADSUPER UniProtKB/TrEMBL
PROSITE XPG_1 UniProtKB/TrEMBL
  XPG_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000056209 RatGTEx
SMART HhH2 UniProtKB/TrEMBL
  XPGI UniProtKB/TrEMBL
  XPGN UniProtKB/TrEMBL
Superfamily-SCOP 5_3_exo_C UniProtKB/TrEMBL
  SSF88723 UniProtKB/TrEMBL
UniProt A0A0G2K4W8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A158 ENTREZGENE, UniProtKB/TrEMBL
  A6JGC0_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Exo1  exonuclease 1   Exo1_predicted  exonuclease 1 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Exo1_predicted  exonuclease 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED