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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1309465 Species: Rattus norvegicus RGD Object: Gene Symbol: Exo1 Name: exonuclease 1

Acc ID: CHEBI:2504 Term: aflatoxin B1 Definition: An aflatoxin having a tetrahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene skeleton with oxygen functionality at positions 1, 4 and 11. CasRN: 1162-65-8 Chemical ID: MESH:D016604

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
affects expression	ISO	RGD:1319820	6480464	CTD	Aflatoxin B1 affects the expression of EXO1 protein	PMID:20106945
increases expression	ISO	RGD:1319820	6480464	CTD	Aflatoxin B1 results in increased expression of EXO1 mRNA	PMID:22100608