Ppp4r3b (protein phosphatase 4, regulatory subunit 3B) - Rat Genome Database

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Pathways
Gene: Ppp4r3b (protein phosphatase 4, regulatory subunit 3B) Rattus norvegicus
Analyze
Symbol: Ppp4r3b
Name: protein phosphatase 4, regulatory subunit 3B
RGD ID: 1309450
Description: Predicted to enable protein phosphatase activator activity. Predicted to be involved in DNA damage response and regulation of double-strand break repair. Predicted to act upstream of or within positive regulation of gluconeogenesis. Predicted to be located in chromatin; cytoplasm; and nucleus. Predicted to be part of protein phosphatase 4 complex. Predicted to be active in nucleoplasm. Orthologous to human PPP4R3B (protein phosphatase 4 regulatory subunit 3B); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC360993; RGD1309450; serine/threonine-protein phosphatase 4 regulatory subunit 3B; similar to KIAA2010 protein; SMEK homolog 2, suppressor of mek1; SMEK homolog 2, suppressor of mek1 (Dictyostelium); Smek2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Candidate Gene For: Scl59
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr814107,118,116 - 107,166,121 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl14107,118,131 - 107,166,134 (+)EnsemblGRCr8
mRatBN7.214102,917,043 - 102,965,210 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl14102,917,443 - 103,068,192 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx14107,252,365 - 107,300,140 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.014108,489,142 - 108,536,906 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.014104,961,558 - 105,009,324 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.014113,570,150 - 113,618,138 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl14113,570,150 - 113,618,138 (+)Ensemblrn6Rnor6.0
Rnor_5.014113,245,254 - 113,293,262 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.414110,170,267 - 110,219,298 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera14101,802,954 - 101,850,699 (+)NCBICelera
Cytogenetic Map14q22NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2-hydroxypropanoic acid  (ISO)
2-methylcholine  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
6-propyl-2-thiouracil  (EXP)
acrolein  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
alpha-pinene  (ISO)
amitrole  (EXP)
antirheumatic drug  (ISO)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
cycloheximide  (ISO)
cyclosporin A  (ISO)
decabromodiphenyl ether  (ISO)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
ethyl methanesulfonate  (ISO)
flutamide  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
gentamycin  (EXP)
hydrogen peroxide  (ISO)
Indeno[1,2,3-cd]pyrene  (ISO)
irinotecan  (ISO)
methimazole  (EXP)
methylmercury chloride  (ISO)
miconazole  (ISO)
nimesulide  (EXP)
ozone  (ISO)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
theophylline  (ISO)
titanium dioxide  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vincristine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
centrosome  (IEA,ISO)
chromatin  (IEA,ISO)
cytoplasm  (IEA,ISO)
nuclear speck  (IEA,ISO)
nucleoplasm  (IBA,IEA,ISO)
nucleus  (IEA,ISO)
protein phosphatase 4 complex  (IBA,IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Identification of SMEK2 as a candidate gene for regulation of responsiveness to dietary cholesterol in rats. Asahina M, etal., J Lipid Res. 2008 Aug 27.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:20876121   PMID:36810603  


Genomics

Comparative Map Data
Ppp4r3b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr814107,118,116 - 107,166,121 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl14107,118,131 - 107,166,134 (+)EnsemblGRCr8
mRatBN7.214102,917,043 - 102,965,210 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl14102,917,443 - 103,068,192 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx14107,252,365 - 107,300,140 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.014108,489,142 - 108,536,906 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.014104,961,558 - 105,009,324 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.014113,570,150 - 113,618,138 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl14113,570,150 - 113,618,138 (+)Ensemblrn6Rnor6.0
Rnor_5.014113,245,254 - 113,293,262 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.414110,170,267 - 110,219,298 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera14101,802,954 - 101,850,699 (+)NCBICelera
Cytogenetic Map14q22NCBI
PPP4R3B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38255,547,292 - 55,617,622 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl255,547,292 - 55,618,880 (-)Ensemblhg38GRCh38
GRCh37255,774,428 - 55,844,757 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36255,629,018 - 55,698,253 (-)NCBIBuild 36Build 36hg18NCBI36
Celera255,615,913 - 55,685,202 (-)NCBICelera
Cytogenetic Map2p16.1NCBI
HuRef255,510,771 - 55,579,889 (-)NCBIHuRef
CHM1_1255,706,132 - 55,775,348 (-)NCBICHM1_1
T2T-CHM13v2.0255,544,479 - 55,614,812 (-)NCBIT2T-CHM13v2.0
Ppp4r3b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391129,118,053 - 29,170,797 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1129,122,890 - 29,170,797 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381129,172,976 - 29,220,797 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1129,172,890 - 29,220,797 (+)Ensemblmm10GRCm38
MGSCv371129,072,907 - 29,120,797 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361129,072,996 - 29,119,136 (+)NCBIMGSCv36mm8
Celera1131,537,111 - 31,586,624 (+)NCBICelera
Cytogenetic Map11A3.3NCBI
cM Map1116.46NCBI
Ppp4r3b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542427,461,921 - 27,520,469 (+)Ensembl
ChiLan1.0NW_00495542427,461,919 - 27,520,649 (+)NCBIChiLan1.0ChiLan1.0
PPP4R3B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21270,697,304 - 70,817,053 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A70,704,786 - 70,820,013 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A55,699,379 - 55,775,193 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A56,842,926 - 56,914,393 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A56,842,926 - 56,914,393 (-)EnsemblpanPan2panpan1.1
PPP4R3B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11056,405,121 - 56,467,907 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1056,406,520 - 56,467,734 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1056,361,616 - 56,424,292 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01057,409,138 - 57,471,878 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1057,409,145 - 57,472,014 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11057,110,910 - 57,173,346 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01057,390,084 - 57,452,524 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01057,680,950 - 57,743,461 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ppp4r3b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629226,589,338 - 26,652,698 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364911,918,637 - 1,981,954 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364911,917,559 - 1,981,954 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PPP4R3B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl385,650,068 - 85,711,120 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1385,650,064 - 85,708,808 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2390,547,020 - 90,592,317 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PPP4R3B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11451,285,538 - 51,356,676 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1451,285,994 - 51,355,142 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604560,362,931 - 60,435,512 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ppp4r3b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248335,936,196 - 6,009,565 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Ppp4r3b
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11196,789,986 - 96,838,306 (+)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:312
Count of miRNA genes:179
Interacting mature miRNAs:233
Transcripts:ENSRNOT00000005170
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1462398852107398852Rat
1641900Alcrsp11Alcohol response QTL 11alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)1474255551109089856Rat
1582259Gluco23Glucose level QTL 233.10.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1474255551109089856Rat

Markers in Region
RH141724  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr814107,165,485 - 107,165,693 (+)Marker Load Pipeline
mRatBN7.214102,964,554 - 102,964,762 (+)MAPPERmRatBN7.2
Rnor_6.014113,617,503 - 113,617,710NCBIRnor6.0
Rnor_5.014113,292,607 - 113,292,814UniSTSRnor5.0
RGSC_v3.414110,218,663 - 110,218,870UniSTSRGSC3.4
Celera14101,850,064 - 101,850,271UniSTS
Cytogenetic Map14q22UniSTS
D3S4227  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.214102,964,261 - 102,964,409 (+)MAPPERmRatBN7.2
Rnor_6.014113,617,210 - 113,617,357NCBIRnor6.0
Rnor_5.014113,292,314 - 113,292,461UniSTSRnor5.0
RGSC_v3.414110,218,370 - 110,218,517UniSTSRGSC3.4
Celera14101,849,771 - 101,849,918UniSTS
Cytogenetic Map14q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000005170   ⟹   ENSRNOP00000005170
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl14107,118,692 - 107,166,134 (+)Ensembl
mRatBN7.2 Ensembl14102,917,443 - 103,068,192 (+)Ensembl
Rnor_6.0 Ensembl14113,570,150 - 113,618,138 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000166473   ⟹   ENSRNOP00000098685
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl14107,118,131 - 107,165,363 (+)Ensembl
RefSeq Acc Id: NM_001108367   ⟹   NP_001101837
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr814107,118,133 - 107,166,121 (+)NCBI
mRatBN7.214102,917,202 - 102,965,190 (+)NCBI
Rnor_6.014113,570,150 - 113,618,138 (+)NCBI
Rnor_5.014113,245,254 - 113,293,262 (+)NCBI
RGSC_v3.414110,170,267 - 110,219,298 (+)RGD
Celera14101,802,954 - 101,850,699 (+)RGD
Sequence:
RefSeq Acc Id: XR_005492993
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr814107,118,116 - 107,156,964 (+)NCBI
mRatBN7.214102,917,043 - 102,956,067 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001101837 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL98023 (Get FASTA)   NCBI Sequence Viewer  
  EDL98024 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000005170.5
  ENSRNOP00000098685
  ENSRNOP00000098685.1
RefSeq Acc Id: NP_001101837   ⟸   NM_001108367
- UniProtKB: D3ZCR4 (UniProtKB/TrEMBL),   A6JQA6 (UniProtKB/TrEMBL),   A6JQA8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000005170   ⟸   ENSRNOT00000005170
Ensembl Acc Id: ENSRNOP00000098685   ⟸   ENSRNOT00000166473
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZCR4-F1-model_v2 AlphaFold D3ZCR4 1-820 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699531
Promoter ID:EPDNEW_R10055
Type:multiple initiation site
Name:Ppp4r3b_1
Description:protein phosphatase 4, regulatory subunit 3B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.014113,570,160 - 113,570,220EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309450 AgrOrtholog
BioCyc Gene G2FUF-14656 BioCyc
Ensembl Genes ENSRNOG00000003712 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000005170.7 UniProtKB/TrEMBL
  ENSRNOT00000166473 ENTREZGENE
  ENSRNOT00000166473.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  DUF625 UniProtKB/TrEMBL
  EVH1_PP4R3 UniProtKB/TrEMBL
  PH_like_dom UniProtKB/TrEMBL
  PP4_regulatory_subunit_3 UniProtKB/TrEMBL
KEGG Report rno:360993 UniProtKB/TrEMBL
NCBI Gene 360993 ENTREZGENE
PANTHER ATP SYNTHASE GAMMA-RELATED UniProtKB/TrEMBL
  SERINE/THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 3B UniProtKB/TrEMBL
Pfam EVH1_PP4R3 UniProtKB/TrEMBL
  SMK-1 UniProtKB/TrEMBL
PhenoGen Ppp4r3b PhenoGen
RatGTEx ENSRNOG00000003712 RatGTEx
Superfamily-SCOP ARM-type_fold UniProtKB/TrEMBL
  PH domain-like UniProtKB/TrEMBL
UniProt A0ABK0L3P9_RAT UniProtKB/TrEMBL
  A6JQA6 ENTREZGENE, UniProtKB/TrEMBL
  A6JQA8 ENTREZGENE, UniProtKB/TrEMBL
  D3ZCR4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-07-01 Ppp4r3b  protein phosphatase 4, regulatory subunit 3B  Smek2  SMEK homolog 2, suppressor of mek1 (Dictyostelium)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-26 Smek2  SMEK homolog 2, suppressor of mek1 (Dictyostelium)  RGD1309450_predicted  similar to KIAA2010 protein (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 RGD1309450_predicted  similar to KIAA2010 protein (predicted)  LOC360993_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC360993_predicted  similar to KIAA2010 protein (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL