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Gene: Nxt1 (nuclear transport factor 2-like export factor 1) Rattus norvegicus

Analyze

Symbol:

Nxt1

Name:

nuclear transport factor 2-like export factor 1

RGD ID:

1309327

Description:

Predicted to enable small GTPase binding activity. Predicted to be involved in poly(A)+ mRNA export from nucleus. Predicted to act upstream of or within RNA export from nucleus and protein export from nucleus. Predicted to be located in nucleus. Predicted to be part of nuclear RNA export factor complex and nuclear pore central transport channel. Orthologous to human NXT1 (nuclear transport factor 2 like export factor 1); PARTICIPATES IN NXF1-NXT1 export pathway; influenza A pathway; mRNA decay pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC296219; NTF2-like export factor 1; NTF2-related export protein 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	156,562,121 - 156,565,043 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	156,560,556 - 156,565,996 (+)	Ensembl				GRCr8
mRatBN7.2	3	136,108,975 - 136,111,897 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	136,108,862 - 136,111,907 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	140,060,861 - 140,063,991 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	148,645,009 - 148,648,139 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	146,334,588 - 146,337,508 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	142,993,658 - 142,996,580 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	142,993,658 - 142,996,578 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	149,404,217 - 149,407,139 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	137,404,957 - 137,407,879 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	134,952,038 - 134,954,960 (+)	NCBI		Celera
RGSC_v3.1	3	137,310,467 - 137,313,449 (+)	NCBI
Cytogenetic Map	3	q41	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-demecolcine (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

2-hydroxypropanoic acid (ISO)

6-propyl-2-thiouracil (EXP)

afimoxifene (ISO)

aflatoxin B1 (ISO)

amitrole (EXP)

arsane (ISO)

arsenic atom (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP)

Butylbenzyl phthalate (ISO)

C60 fullerene (EXP)

cadmium dichloride (ISO)

carbon nanotube (ISO)

chloropicrin (ISO)

chlorpyrifos (ISO)

chromium(6+) (ISO)

cisplatin (ISO)

cyclosporin A (ISO)

dibutyl phthalate (ISO)

disodium selenite (ISO)

endosulfan (EXP)

epoxiconazole (ISO)

flutamide (EXP)

formaldehyde (ISO)

gentamycin (EXP)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

methimazole (EXP)

methylparaben (ISO)

nickel atom (ISO)

nitrates (ISO)

oxaliplatin (EXP)

paracetamol (EXP,ISO)

phenobarbital (ISO)

pirinixic acid (ISO)

rac-lactic acid (ISO)

sirolimus (ISO)

sodium arsenite (ISO)

sulfadimethoxine (EXP)

temozolomide (ISO)

tetrachloromethane (ISO)

thioacetamide (EXP)

topotecan (EXP)

triadimefon (EXP)

tungsten (ISO)

urethane (ISO)

valproic acid (ISO)

vincristine (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

mRNA export from nucleus (ISO)

mRNA transport (IEA)

nucleocytoplasmic transport (IEA)

poly(A)+ mRNA export from nucleus (IBA)

protein export from nucleus (ISO)

protein transport (IEA)

RNA export from nucleus (ISO)

Cellular Component

cytoplasm (IEA)

cytosol (ISO)

nuclear pore (ISO)

nuclear pore central transport channel (IBA)

nucleoplasm (ISO)

nucleus (IEA,ISO)

Molecular Function

protein binding (ISO)

small GTPase binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

influenza A pathway (IEA)

mRNA decay pathway (IEA)

NXF1-NXT1 export pathway (ISO)

ribosome biogenesis pathway (IEA)

RNA transport pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	Postage for the messenger: designating routes for nuclear mRNA export.	Natalizio BJ and Wente SR, Trends Cell Biol. 2013 Aug;23(8):365-73. doi: 10.1016/j.tcb.2013.03.006. Epub 2013 Apr 11.
5.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:10567585	PMID:11579093	PMID:12477932	PMID:35219094

Genomics

Comparative Map Data

Nxt1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	156,562,121 - 156,565,043 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	156,560,556 - 156,565,996 (+)	Ensembl				GRCr8
mRatBN7.2	3	136,108,975 - 136,111,897 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	136,108,862 - 136,111,907 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	140,060,861 - 140,063,991 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	148,645,009 - 148,648,139 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	146,334,588 - 146,337,508 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	142,993,658 - 142,996,580 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	142,993,658 - 142,996,578 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	149,404,217 - 149,407,139 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	137,404,957 - 137,407,879 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	134,952,038 - 134,954,960 (+)	NCBI		Celera
RGSC_v3.1	3	137,310,467 - 137,313,449 (+)	NCBI
Cytogenetic Map	3	q41	NCBI

NXT1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	20	23,350,791 - 23,354,771 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	20	23,350,767 - 23,354,771 (+)	Ensembl			hg38	GRCh38
GRCh37	20	23,331,428 - 23,335,408 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	20	23,279,373 - 23,283,408 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	20	23,279,372 - 23,283,408	NCBI
Celera	20	23,404,748 - 23,408,783 (+)	NCBI		Celera
Cytogenetic Map	20	p11.21	NCBI
HuRef	20	23,292,698 - 23,296,733 (+)	NCBI		HuRef
CHM1_1	20	23,331,839 - 23,335,874 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	20	23,410,333 - 23,414,313 (+)	NCBI		T2T-CHM13v2.0

Nxt1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	148,514,535 - 148,517,946 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	148,514,521 - 148,517,947 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	2	148,672,615 - 148,676,026 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	148,672,601 - 148,676,027 (+)	Ensembl			mm10	GRCm38
MGSCv37	2	148,498,351 - 148,501,762 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	2	148,364,083 - 148,367,464 (+)	NCBI		MGSCv36	mm8
Celera	2	149,940,706 - 149,944,117 (+)	NCBI		Celera
Cytogenetic Map	2	G3	NCBI
cM Map	2	73.53	NCBI

Nxt1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955415	30,366,993 - 30,369,688 (+)	Ensembl
ChiLan1.0	NW_004955415	30,366,993 - 30,369,688 (+)	NCBI	ChiLan1.0	ChiLan1.0

NXT1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	21	24,216,690 - 24,227,958 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	20	24,215,445 - 24,224,791 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	20	23,292,400 - 23,296,427 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	20	23,643,785 - 23,647,856 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	20	23,647,127 - 23,647,549 (+)	Ensembl			panPan2	panpan1.1

NXT1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	24	295,064 - 299,316 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	24	316,792 - 320,578 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	24	687,393 - 691,169 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
UMICH_Zoey_3.1	24	289,661 - 293,447 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	24	389,052 - 392,833 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	24	672,963 - 676,752 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Nxt1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	148,822,722 - 148,825,799 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936620	2,243,210 - 2,246,119 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936620	2,243,181 - 2,246,244 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NXT1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	17	30,338,391 - 30,341,628 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	17	30,338,379 - 30,341,629 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	17	34,427,323 - 34,430,564 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NXT1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	52,357,189 - 52,361,222 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	2	52,360,491 - 52,360,913 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666078	7,173,093 - 7,177,137 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Nxt1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624741	23,021,076 - 23,023,416 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624741	23,021,247 - 23,023,327 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Nxt1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	5	128,207,047 - 128,207,816 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Nxt1
9 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	40
Count of miRNA genes:	33
Interacting mature miRNAs:	39
Transcripts:	ENSRNOT00000006205
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
12879876	Bw182	Body weight QTL 182		0.003	body mass (VT:0001259)	body weight (CMO:0000012)	3	141555229	186555229	Rat
2301411	Bp320	Blood pressure QTL 320		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	141555229	186555229	Rat
1582233	Insul10	Insulin level QTL 10	5.4	0.0015	blood insulin amount (VT:0001560)	serum insulin level times blood glucose level (CMO:0002040)	3	133259579	178259579	Rat
12879872	Cm97	Cardiac mass QTL 97		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	141555229	186555229	Rat
12879873	Cm96	Cardiac mass QTL 96		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	3	141555229	186555229	Rat
1578653	Vnigr3	Vascular neointimal growth QTL 3	3.1		artery morphology trait (VT:0002191)	artery neointimal hyperplastic lesion area (CMO:0001414)	3	151075912	189428310	Rat
2302373	Gluco39	Glucose level QTL 39	5.01		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	3	129154923	182114333	Rat
12879874	Cm98	Cardiac mass QTL 98		0.005	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	3	141555229	186555229	Rat
12879875	Kidm64	Kidney mass QTL 64		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	141555229	186555229	Rat
70216	Cm14	Cardiac mass QTL 14	2.1		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	51581665	184004958	Rat
2292591	Esta4	Estrogen-induced thymic atrophy QTL 4			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	3	67641776	167835660	Rat
1578754	Stresp16	Stress response QTL 16	4	0.001	blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	3	133134628	178134628	Rat
1582213	Insul6	Insulin level QTL 6	3.7	0.0009	blood insulin amount (VT:0001560)	calculated serum insulin level (CMO:0000359)	3	155759447	189428310	Rat
1300173	Rf11	Renal function QTL 11	3.38		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	3	141508991	166376254	Rat
9589106	Insul23	Insulin level QTL 23	13.86	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	3	152055202	189428310	Rat
8694437	Bw167	Body weight QTL 167	22.46	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	3	112250810	157250810	Rat
10755461	Coatc16	Coat color QTL 16			coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	3	142898802	187898802	Rat
8662816	Vetf4	Vascular elastic tissue fragility QTL 4	4		renal artery integrity trait (VT:0010642)	number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)	3	79649560	177741895	Rat
1559282	Emca5	Estrogen-induced mammary cancer QTL 5	3.9		mammary gland integrity trait (VT:0010552)	percentage of study population developing mammary tumors during a period of time (CMO:0000948)	3	145335553	189428310	Rat
1354611	Despr2	Despair related QTL 2	3.03	0.0028	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	3	117537367	162537367	Rat
2303620	Vencon4	Ventilatory control QTL 4	3.9		respiration trait (VT:0001943)	tidal volume (CMO:0000222)	3	125116475	170116475	Rat
1582256	Insul9	Insulin level QTL 9	4.4	0.0016	blood insulin amount (VT:0001560)	absolute change in serum insulin level (CMO:0002038)	3	155759447	189428310	Rat
1576306	Schws3	Schwannoma susceptibility QTL 3		0.001	nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	3	139299381	184299381	Rat
5686842	Rf59	Renal function QTL 59			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	3	122395989	167395989	Rat
1300159	Kidm4	Kidney mass QTL 4	3.83		kidney mass (VT:0002707)	right kidney wet weight to body weight ratio (CMO:0001953)	3	141508991	177728348	Rat
2301971	Cm71	Cardiac mass QTL 71	4.63		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	3	131036586	176036586	Rat
631673	Iddm13	Insulin dependent diabetes mellitus QTL 13	1.3	0.663	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	3	137114333	182114333	Rat
1582248	Insul7	Insulin level QTL 7	3.9	0.0041	blood insulin amount (VT:0001560)	calculated serum insulin level (CMO:0000359)	3	155759447	189428310	Rat
2301970	Bw81	Body weight QTL 81	5.19		body mass (VT:0001259)	body weight (CMO:0000012)	3	131036586	176036586	Rat
1581546	Pur13	Proteinuria QTL 13	2.93	0.0335	urine total protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	3	98651826	167012663	Rat
1578666	Vnigr1	Vascular neointimal growth QTL 1	4.6		artery morphology trait (VT:0002191)	artery lumen area (CMO:0001409)	3	151075912	189428310	Rat
1578656	Vnigr2	Vascular neointimal growth QTL 2	4.2		artery morphology trait (VT:0002191)	lesioned artery residual lumen area (CMO:0001417)	3	151075912	189428310	Rat
12879871	Am7	Aortic mass QTL 7		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	3	141555229	186555229	Rat
631541	Bp81	Blood pressure QTL 81	4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	144575244	189428310	Rat
724532	Cm17	Cardiac mass QTL 17	2		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	3	116188400	161188400	Rat

Markers in Region

AA891920

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	136,111,498 - 136,111,707 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	142,996,182 - 142,996,390	NCBI	Rnor6.0
Rnor_5.0	3	149,406,741 - 149,406,949	UniSTS	Rnor5.0
RGSC_v3.4	3	137,407,481 - 137,407,689	UniSTS	RGSC3.4
Celera	3	134,954,562 - 134,954,770	UniSTS
RH 3.4 Map	3	1094.41	UniSTS
Cytogenetic Map	3	q41	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001106521	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC110699	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC167042	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474026	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ220038	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ227988	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ231864	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ233990	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000006205 ⟹ ENSRNOP00000006205

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	156,561,711 - 156,565,163 (+)	Ensembl
mRatBN7.2 Ensembl	3	136,108,862 - 136,111,907 (+)	Ensembl
Rnor_6.0 Ensembl	3	142,993,658 - 142,996,578 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000127431 ⟹ ENSRNOP00000110913

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	156,562,253 - 156,565,690 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000164872 ⟹ ENSRNOP00000106679

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	156,560,556 - 156,565,996 (+)	Ensembl

RefSeq Acc Id:

NM_001106521 ⟹ NP_001099991

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	156,562,121 - 156,565,043 (+)	NCBI
mRatBN7.2	3	136,108,975 - 136,111,897 (+)	NCBI
Rnor_6.0	3	142,993,658 - 142,996,580 (+)	NCBI
Rnor_5.0	3	149,404,217 - 149,407,139 (+)	NCBI
RGSC_v3.4	3	137,404,957 - 137,407,879 (+)	RGD
Celera	3	134,952,038 - 134,954,960 (+)	RGD

Sequence:

show sequence

CTAGGAGGAAGAGGAGAACAAGAGAGAAACTCTTCTGGCCCGGGACCGCGGCCCGGGCGGGACC
CGGGGCCGAGTCGCCTAGGCGACGTTGACCGAGACCGAGCAGTCACTGGATCCCTAAGGAGGCG
GCATTCTGGCAGAGGCCTCTGGCAGCAGACCCAGAGATGGCATCAGTAGATTTCAAGACCTATG
TGGACCAGGCCTGCAGAGCTGCAGAGGAATTTGTCAACGTCTACTACACTACTATGGATAATCG
GCGGCGGCTGCTGTCTCGCCTGTACATGGGCACGGCCACTTTAGTATGGAATGGAAATGCCGTT
TCGGGACAAGAATCCTTGAGTGAGTTTTTTGAGATGTTGCCTTCCAGTGAGTTCCAAATCAACG
TGGTAGACTGCCAGCCTGTTCATGATGAAGCTACGCCAAGCCAGACCACGGTCCTTGTGGTCAT
CTGTGGAACAGTGAAATTTGAGGGCAACAAACAGCGGGACTTCAACCAGAACTTCATCCTGACT
GCTCAGGCGTCACCCAGTAACACAGTGTGGAAGATAGCGAGTGACTGCTTCCGCTTCCAGGACT
GGGCCAGCTAGTGGGGGTGACAAAGGCAGCTTGGCTTTAGCCAAGCTCTGCAGAGAAATGCCAG
TCTCAAATCTCAGGACGTGGAGAACACTAGTTCATTTTTGTTGTCACAGCAGCACTGCAAACTG
GATGTTCGACTCCTAGAAACCCCTTTCCTGGTTATATACTGGTTTGTCATAGTTGCCTTTTAAA
AGTAGTAAACTTTCTATTTTTCTACTTACTCAGTAGAGAACCTGTTTCTGGAAATTGACAAATA
AATATGCTGCTTCTCTGCCTAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001099991	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI67042	(Get FASTA)	NCBI Sequence Viewer
	EDL95097	(Get FASTA)	NCBI Sequence Viewer
	EDL95098	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000006205
	ENSRNOP00000006205.4
	ENSRNOP00000106679.1
	ENSRNOP00000110913.1

RefSeq Acc Id:	NP_001099991 ⟸ NM_001106521
- UniProtKB:	B2RZ65 (UniProtKB/TrEMBL), F7EK82 (UniProtKB/TrEMBL)
- Sequence:	show sequence MASVDFKTYVDQACRAAEEFVNVYYTTMDNRRRLLSRLYMGTATLVWNGNAVSGQESLSEFFEM LPSSEFQINVVDCQPVHDEATPSQTTVLVVICGTVKFEGNKQRDFNQNFILTAQASPSNTVWKI ASDCFRFQDWAS hide sequence

Ensembl Acc Id:

ENSRNOP00000006205 ⟸ ENSRNOT00000006205

Ensembl Acc Id:

ENSRNOP00000110913 ⟸ ENSRNOT00000127431

Ensembl Acc Id:

ENSRNOP00000106679 ⟸ ENSRNOT00000164872

Protein Domains

NTF2

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-B2RZ65-F1-model_v2	AlphaFold	B2RZ65	1-140	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13692496

Promoter ID:

EPDNEW_R3021

Type:

initiation region

Name:

Nxt1_1

Description:

nuclear transport factor 2-like export factor 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	3	142,993,643 - 142,993,703	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1309327	AgrOrtholog
BioCyc Gene	G2FUF-47500	BioCyc
Ensembl Genes	ENSRNOG00000004700	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000006205	ENTREZGENE
	ENSRNOT00000006205.9	UniProtKB/TrEMBL
	ENSRNOT00000127431.1	UniProtKB/TrEMBL
	ENSRNOT00000164872.1	UniProtKB/TrEMBL
Gene3D-CATH	3.10.450.50	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7444530	IMAGE-MGC_LOAD
InterPro	NTF2	UniProtKB/TrEMBL
	NTF2-like_dom	UniProtKB/TrEMBL
	NTF2/Mtr2	UniProtKB/TrEMBL
	Nuclear_transport_factor_2_euk	UniProtKB/TrEMBL
KEGG Report	rno:296219	UniProtKB/TrEMBL
MGC_CLONE	MGC:189309	IMAGE-MGC_LOAD
NCBI Gene	296219	ENTREZGENE
PANTHER	PTHR12612	UniProtKB/TrEMBL
Pfam	NTF2	UniProtKB/TrEMBL
PhenoGen	Nxt1	PhenoGen
PROSITE	NTF2_DOMAIN	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000004700	RatGTEx
Superfamily-SCOP	SSF54427	UniProtKB/TrEMBL
UniProt	B2RZ65	ENTREZGENE, UniProtKB/TrEMBL
	F7EK82	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2014-05-21	Nxt1	nuclear transport factor 2-like export factor 1	Nxt1	NTF2-like export factor 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-09-09	Nxt1	NTF2-like export factor 1	Nxt1	NTF2-related export protein 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Nxt1	NTF2-related export protein 1	Nxt1_predicted	NTF2-related export protein 1 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Nxt1_predicted	NTF2-related export protein 1 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

RGD Manual Annotations

Imported Annotations - KEGG (archival)

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RGD Manual Annotations

Imported Annotations - KEGG (archival)