Srsf3 (serine and arginine rich splicing factor 3) - Rat Genome Database

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Gene: Srsf3 (serine and arginine rich splicing factor 3) Rattus norvegicus
Analyze
Symbol: Srsf3
Name: serine and arginine rich splicing factor 3
RGD ID: 1309233
Description: Enables sequence-specific mRNA binding activity. Predicted to be involved in mRNA export from nucleus; primary miRNA processing; and regulation of alternative mRNA splicing, via spliceosome. Predicted to act upstream of or within cellular response to leukemia inhibitory factor. Predicted to be located in cytoplasm and nucleus. Predicted to be active in nuclear speck. Orthologous to human SRSF3 (serine and arginine rich splicing factor 3); PARTICIPATES IN spliceosome pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC361814; serine/arginine-rich splicing factor 3; Sfrs3; splicing factor, arginine/serine-rich 3; splicing factor, arginine/serine-rich 3 (SRp20)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8207,093,529 - 7,103,517 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl207,093,565 - 7,103,516 (+)EnsemblGRCr8
mRatBN7.2207,091,928 - 7,101,860 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl207,091,910 - 7,101,078 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx207,803,145 - 7,813,066 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0207,165,002 - 7,174,923 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0207,639,798 - 7,649,730 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0206,288,285 - 6,298,218 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl206,288,267 - 6,298,213 (+)Ensemblrn6Rnor6.0
Rnor_5.0208,534,919 - 8,544,852 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4207,316,649 - 7,326,580 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera208,643,622 - 8,653,553 (+)NCBICelera
RGSC_v3.1207,316,875 - 7,326,807 (+)NCBI
Cytogenetic Map20p12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
14-Deoxy-11,12-didehydroandrographolide  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,6-dimethoxyphenol  (ISO)
2-amino-2-deoxy-D-glucopyranose  (ISO)
3',5'-cyclic UMP  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,3',5-triiodo-L-thyronine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (EXP,ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucosamine  (ISO)
all-trans-retinoic acid  (ISO)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-D-glucosamine  (ISO)
bisphenol A  (EXP,ISO)
buspirone  (EXP)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
cadmium sulfate  (ISO)
carbon nanotube  (ISO)
cisplatin  (ISO)
cocaine  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
curcumin  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
decabromodiphenyl ether  (ISO)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
dioxygen  (ISO)
diquat  (ISO)
disodium selenite  (ISO)
diuron  (ISO)
dorsomorphin  (ISO)
enzyme inhibitor  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
ethylisopropylamiloride  (ISO)
flutamide  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
furfural  (ISO)
gentamycin  (EXP)
glyphosate  (ISO)
gold atom  (ISO)
gold(0)  (ISO)
hydrogen peroxide  (ISO)
ivermectin  (ISO)
lead(0)  (ISO)
lithium atom  (ISO)
lithium hydride  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
methylparaben  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nitrates  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
pentachlorophenol  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pinosylvin  (ISO)
pirinixic acid  (ISO)
piroxicam  (ISO)
quercetin  (ISO)
raloxifene  (EXP)
resveratrol  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium chloride  (ISO)
sodium dichromate  (ISO)
succimer  (ISO)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
tamibarotene  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (ISO)
thapsigargin  (ISO)
theophylline  (ISO)
thioacetamide  (EXP)
trans-pinosylvin  (ISO)
trichloroethene  (EXP,ISO)
triptonide  (ISO)
trovafloxacin  (EXP)
tungsten  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vincristine  (ISO)
Yessotoxin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
nuclear speck  (IBA,IEA,ISO)
nucleoplasm  (IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Differentially expressed genes after peripheral nerve injury. Gillen C, etal., J Neurosci Res. 1995 Oct 1;42(2):159-71.
3. Alterations in expression pattern of splicing factors in epithelial ovarian cancer and its clinical impact. Iborra S, etal., Int J Gynecol Cancer. 2013 Jul;23(6):990-6. doi: 10.1097/IGC.0b013e31829783e3.
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
7. Serine arginine splicing factor 3 is involved in enhanced splicing of glucose-6-phosphate dehydrogenase RNA in response to nutrients and hormones in liver. Walsh CM, etal., J Biol Chem. 2013 Jan 25;288(4):2816-28. doi: 10.1074/jbc.M112.410803. Epub 2012 Dec 11.
8. Increased expression of splicing factor SRp20 mRNA in bipolar disorder patients. Watanuki T, etal., J Affect Disord. 2008 Sep;110(1-2):62-9. doi: 10.1016/j.jad.2008.01.003. Epub 2008 Feb 20.
Additional References at PubMed
PMID:17022104   PMID:20439489   PMID:22658674   PMID:22681889   PMID:26876937   PMID:28984244   PMID:31505169  


Genomics

Comparative Map Data
Srsf3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8207,093,529 - 7,103,517 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl207,093,565 - 7,103,516 (+)EnsemblGRCr8
mRatBN7.2207,091,928 - 7,101,860 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl207,091,910 - 7,101,078 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx207,803,145 - 7,813,066 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0207,165,002 - 7,174,923 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0207,639,798 - 7,649,730 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0206,288,285 - 6,298,218 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl206,288,267 - 6,298,213 (+)Ensemblrn6Rnor6.0
Rnor_5.0208,534,919 - 8,544,852 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4207,316,649 - 7,326,580 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera208,643,622 - 8,653,553 (+)NCBICelera
RGSC_v3.1207,316,875 - 7,326,807 (+)NCBI
Cytogenetic Map20p12NCBI
SRSF3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38636,594,362 - 36,605,600 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl636,593,787 - 36,605,911 (+)Ensemblhg38GRCh38
GRCh37636,562,139 - 36,573,377 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36636,670,144 - 36,679,187 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34636,670,143 - 36,679,187NCBI
Celera638,117,136 - 38,127,290 (+)NCBICelera
Cytogenetic Map6p21.31-p21.2NCBI
HuRef636,280,649 - 36,290,802 (+)NCBIHuRef
CHM1_1636,563,858 - 36,574,011 (+)NCBICHM1_1
T2T-CHM13v2.0636,415,006 - 36,426,242 (+)NCBIT2T-CHM13v2.0
Srsf3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391729,251,634 - 29,262,346 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1729,251,602 - 29,262,347 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381729,032,660 - 29,043,372 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1729,032,628 - 29,043,373 (+)Ensemblmm10GRCm38
MGSCv371729,169,618 - 29,180,311 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361728,760,340 - 28,771,033 (+)NCBIMGSCv36mm8
Celera1729,589,503 - 29,600,185 (+)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1715.03NCBI
Srsf3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554376,306,151 - 6,314,332 (-)Ensembl
ChiLan1.0NW_0049554376,306,151 - 6,314,332 (-)NCBIChiLan1.0ChiLan1.0
SRSF3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2551,063,055 - 51,072,341 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1646,932,631 - 46,941,830 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0636,157,321 - 36,165,896 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1637,352,484 - 37,362,196 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl637,352,484 - 37,362,195 (+)EnsemblpanPan2panpan1.1
SRSF3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1125,677,879 - 5,686,220 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl125,677,907 - 5,684,446 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha125,696,947 - 5,705,330 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0126,026,006 - 6,034,386 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl126,026,034 - 6,035,139 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1125,681,309 - 5,689,692 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0125,760,111 - 5,768,487 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0125,858,304 - 5,866,684 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Srsf3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494641,160,749 - 41,169,819 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647622,790,411 - 22,799,452 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647622,790,411 - 22,799,498 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SRSF3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl732,289,480 - 32,298,580 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1732,289,464 - 32,298,652 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2737,191,583 - 37,199,370 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SRSF3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11735,535,900 - 35,544,852 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604436,534,264 - 36,542,771 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Srsf3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475421,163,232 - 21,171,058 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462475421,163,232 - 21,171,122 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Srsf3
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1184,826,929 - 4,836,602 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Srsf3
56 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:273
Count of miRNA genes:166
Interacting mature miRNAs:217
Transcripts:ENSRNOT00000000627
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4889610Pancm3Pancreatic morphology QTL 33.750.001pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)20418947649189476Rat
2317057Aia27Adjuvant induced arthritis QTL 272.83joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)20126925056Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20133724594Rat
7387283Uae44Urinary albumin excretion QTL 440.1712urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)20126128279Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600300Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20153308346533083Rat
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124164241Rat
1558640Prcs2Prostate cancer susceptibility QTL 23.3prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)20134066551Rat
1331772Cdexp2CD45RC expression in CD8 T cells QTL 25.7CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)20362632310078622Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129193376Rat
4889857Pur27Proteinuria QTL 2712.20.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20127341128Rat
1300152Bp195Blood pressure QTL 1953.46arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2036263239244918Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129193376Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129193376Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129193376Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129193376Rat
61432Cia1Collagen induced arthritis QTL 1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)20114100378Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127341128Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127341128Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578510Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600300Rat

Markers in Region
RH130376  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2207,101,566 - 7,101,746 (+)MAPPERmRatBN7.2
Rnor_6.0206,297,925 - 6,298,104NCBIRnor6.0
Rnor_5.0208,544,559 - 8,544,738UniSTSRnor5.0
RGSC_v3.4207,326,292 - 7,326,471UniSTSRGSC3.4
Celera208,653,260 - 8,653,439UniSTS
RH 3.4 Map2076.99UniSTS
Cytogenetic Map20p12UniSTS
BE117632  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2207,100,848 - 7,101,013 (+)MAPPERmRatBN7.2
Rnor_6.0206,297,207 - 6,297,371NCBIRnor6.0
Rnor_5.0208,543,841 - 8,544,005UniSTSRnor5.0
RGSC_v3.4207,325,574 - 7,325,738UniSTSRGSC3.4
Celera208,652,542 - 8,652,706UniSTS
RH 3.4 Map2078.1UniSTS
Cytogenetic Map20p12UniSTS
SFRS3_1875  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21472,183,836 - 72,184,468 (+)MAPPERmRatBN7.2
mRatBN7.2207,100,330 - 7,100,942 (+)MAPPERmRatBN7.2
Rnor_6.0206,296,689 - 6,297,300NCBIRnor6.0
Rnor_6.01476,915,830 - 76,916,461NCBIRnor6.0
Rnor_5.0208,543,323 - 8,543,934UniSTSRnor5.0
Rnor_5.01476,900,222 - 76,900,853UniSTSRnor5.0
RGSC_v3.41477,415,088 - 77,415,719UniSTSRGSC3.4
RGSC_v3.4207,325,056 - 7,325,667UniSTSRGSC3.4
Celera208,652,024 - 8,652,635UniSTS
Celera1471,136,127 - 71,136,758UniSTS
Cytogenetic Map20p12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000000627   ⟹   ENSRNOP00000000627
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl206,288,267 - 6,298,213 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000092645
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl206,288,267 - 6,295,943 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000092663   ⟹   ENSRNOP00000075828
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl207,091,910 - 7,100,268 (+)Ensembl
Rnor_6.0 Ensembl206,288,267 - 6,296,790 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000095830   ⟹   ENSRNOP00000086649
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl207,091,990 - 7,100,268 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000117194   ⟹   ENSRNOP00000085609
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl207,093,565 - 7,103,516 (+)Ensembl
mRatBN7.2 Ensembl207,091,910 - 7,101,078 (+)Ensembl
RefSeq Acc Id: NM_001047907   ⟹   NP_001041372
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8207,093,585 - 7,103,517 (+)NCBI
mRatBN7.2207,091,928 - 7,101,860 (+)NCBI
Rnor_6.0206,288,285 - 6,298,218 (+)NCBI
Rnor_5.0208,534,919 - 8,544,852 (+)NCBI
RGSC_v3.4207,316,649 - 7,326,580 (+)RGD
Celera208,643,622 - 8,653,553 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063279228   ⟹   XP_063135298
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8207,093,529 - 7,100,796 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001041372 (Get FASTA)   NCBI Sequence Viewer  
  XP_063135298 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein ABG37970 (Get FASTA)   NCBI Sequence Viewer  
  EDL96950 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000085609
  ENSRNOP00000085609.2
RefSeq Acc Id: NP_001041372   ⟸   NM_001047907
- UniProtKB: Q0ZFS8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000075828   ⟸   ENSRNOT00000092663
Ensembl Acc Id: ENSRNOP00000000627   ⟸   ENSRNOT00000000627
Ensembl Acc Id: ENSRNOP00000086649   ⟸   ENSRNOT00000095830
Ensembl Acc Id: ENSRNOP00000085609   ⟸   ENSRNOT00000117194
RefSeq Acc Id: XP_063135298   ⟸   XM_063279228
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A2L6 (UniProtKB/TrEMBL),   A6JJT3 (UniProtKB/TrEMBL),   A0A8I5ZSN8 (UniProtKB/TrEMBL)
Protein Domains
RRM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q0ZFS8-F1-model_v2 AlphaFold Q0ZFS8 1-164 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701439
Promoter ID:EPDNEW_R11963
Type:single initiation site
Name:Srsf3_1
Description:serine and arginine rich splicing factor 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0206,288,267 - 6,288,327EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309233 AgrOrtholog
BioCyc Gene G2FUF-4396 BioCyc
Ensembl Genes ENSRNOG00000000520 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000117194 ENTREZGENE
  ENSRNOT00000117194.2 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.330 UniProtKB/TrEMBL
InterPro Nucleotide-bd_a/b_plait_sf UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/TrEMBL
  RRM_RNP1 UniProtKB/TrEMBL
  SRSF UniProtKB/TrEMBL
KEGG Report rno:361814 UniProtKB/TrEMBL
NCBI Gene 361814 ENTREZGENE
PANTHER SERINE/ARGININE RICH SPLICING FACTOR UniProtKB/TrEMBL
Pfam RRM_1 UniProtKB/TrEMBL
PhenoGen Srsf3 PhenoGen
PROSITE RRM UniProtKB/TrEMBL
RatGTEx ENSRNOG00000000520 RatGTEx
SMART RRM UniProtKB/TrEMBL
Superfamily-SCOP SSF54928 UniProtKB/TrEMBL
UniProt A0A8I5ZSN8 ENTREZGENE
  A0A8I6A2L6 ENTREZGENE
  A0A8I6A2P1_RAT UniProtKB/TrEMBL
  A6JJT3 ENTREZGENE, UniProtKB/TrEMBL
  Q0ZFS8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-06-15 Srsf3  serine and arginine rich splicing factor 3  Srsf3  serine/arginine-rich splicing factor 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-08-01 Srsf3  serine/arginine-rich splicing factor 3  Sfrs3  splicing factor, arginine/serine-rich 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-07-22 Sfrs3  splicing factor, arginine/serine-rich 3  Srsf3  serine/arginine-rich splicing factor 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-07-13 Srsf3  serine/arginine-rich splicing factor 3  Sfrs3  splicing factor, arginine/serine-rich 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-09-20 Sfrs3  splicing factor, arginine/serine-rich 3  Srsf3  serine/arginine-rich splicing factor 3   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-09-14 Srsf3  serine/arginine-rich splicing factor 3   Sfrs3  splicing factor, arginine/serine-rich 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-11-04 Sfrs3  splicing factor, arginine/serine-rich 3  Sfrs3  splicing factor, arginine/serine-rich 3 (SRp20)   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Sfrs3  splicing factor, arginine/serine-rich 3 (SRp20)   Sfrs3_predicted  splicing factor, arginine/serine-rich 3 (SRp20) (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Sfrs3_predicted  splicing factor, arginine/serine-rich 3 (SRp20) (predicted)      Symbol and Name status set to approved 70820 APPROVED