Dym (dymeclin) - Rat Genome Database

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Gene: Dym (dymeclin) Rattus norvegicus
Analyze
Symbol: Dym
Name: dymeclin
RGD ID: 1309111
Description: Predicted to enable enzyme binding activity. Predicted to be involved in Golgi organization and bone development. Predicted to be located in cytoplasm. Predicted to be active in Golgi apparatus. Human ortholog(s) of this gene implicated in Dyggve-Melchior-Clausen disease; Smith-McCort dysplasia 1; and osteochondrodysplasia. Orthologous to human DYM (dymeclin); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; bis(2-chloroethyl) sulfide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC291433; RGD1309111; similar to RIKEN cDNA 4933427L07
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81870,879,835 - 71,176,006 (+)NCBIGRCr8
mRatBN7.21868,605,131 - 68,900,905 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1868,605,185 - 68,900,903 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1870,718,041 - 71,013,638 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01871,386,410 - 71,683,811 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01869,244,060 - 69,539,675 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01870,996,074 - 71,313,033 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1870,996,044 - 71,313,084 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01870,178,416 - 70,449,688 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41871,889,053 - 72,188,251 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11871,962,174 - 72,261,226 (+)NCBI
Celera1866,780,263 - 67,073,707 (+)NCBICelera
Cytogenetic Map18q12.2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
DymRatosteochondrodysplasia  ISODYM (Homo sapiens)1598787 RGD 
1 to 9 of 9 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
DymRatchromosome 18q deletion syndrome  ISODYM (Homo sapiens)8554872ClinVar Annotator: match by term: Monosomy 18q and deletion 18qClinVarPMID:31690835
DymRatconnective tissue disease  ISODYM (Homo sapiens)8554872ClinVar more ...ClinVarPMID:25741868 and PMID:28492532
DymRatDyggve-Melchior-Clausen disease  ISODYM (Homo sapiens)8554872ClinVar Annotator: match by term: Dyggve-Melchior-Clausen syndromeClinVarPMID:12161821 more ...
DymRatgenetic disease  ISODYM (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:12491225 more ...
DymRatintellectual disability  ISODYM (Homo sapiens)8554872ClinVar Annotator: match by term: Intellectual disabilityClinVar 
DymRatprostate cancer  ISODYM (Homo sapiens)8554872ClinVar Annotator: match by term: Malignant tumor of prostateClinVarPMID:23265383
DymRatschizophrenia  ISODYM (Homo sapiens)8554872ClinVar Annotator: match by term: SchizophreniaClinVar 
DymRatSmith-McCort dysplasia  ISODYM (Homo sapiens)8554872ClinVar Annotator: match by term: Smith-McCort dysplasiaClinVarPMID:25741868 and PMID:28492532
DymRatSmith-McCort dysplasia 1  ISODYM (Homo sapiens)8554872ClinVar more ...ClinVarPMID:12491225 more ...
1 to 9 of 9 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
DymRatDyggve-Melchior-Clausen disease  ISODYM (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTD 
DymRatSmith-McCort dysplasia  ISODYM (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTD 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
DymRatSmith-McCort dysplasia  ISSDym (Mus musculus)13592920 MouseDO 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
DymRatDyggve-Melchior-Clausen disease  ISODYM (Homo sapiens)7240710 OMIM 
DymRatSmith-McCort dysplasia 1  ISODYM (Homo sapiens)7240710 OMIM 

1 to 20 of 62 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
DymRat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISODym (Mus musculus)6480464[Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of DYM mRNACTDPMID:16214954
DymRat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of DYM mRNACTDPMID:33387578 and PMID:34747641
DymRat2,3,7,8-tetrachlorodibenzodioxine affects expressionISODym (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of DYM mRNACTDPMID:21570461
DymRat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of DYM mRNACTDPMID:21215274 and PMID:32109520
DymRat2,3,7,8-tetrachlorodibenzodioxine increases expressionISODym (Mus musculus)6480464Tetrachlorodibenzodioxin results in increased expression of DYM mRNACTDPMID:18796159
DymRat2,3,7,8-Tetrachlorodibenzofuran decreases expressionEXP 64804642 more ...CTDPMID:32109520
DymRataflatoxin B1 affects expressionISODYM (Homo sapiens)6480464Aflatoxin B1 affects the expression of DYM proteinCTDPMID:20106945
DymRataflatoxin B1 increases methylationISODYM (Homo sapiens)6480464Aflatoxin B1 results in increased methylation of DYM intronCTDPMID:30157460
DymRataflatoxin B1 decreases expressionISODym (Mus musculus)6480464Aflatoxin B1 results in decreased expression of DYM mRNACTDPMID:19770486
DymRatall-trans-retinoic acid decreases expressionISODYM (Homo sapiens)6480464Tretinoin results in decreased expression of DYM mRNACTDPMID:33167477
DymRataristolochic acid A decreases expressionISODYM (Homo sapiens)6480464aristolochic acid I results in decreased expression of DYM mRNACTDPMID:33212167
DymRatarsane affects methylationISODYM (Homo sapiens)6480464Arsenic affects the methylation of DYM geneCTDPMID:25304211
DymRatarsenic atom affects methylationISODYM (Homo sapiens)6480464Arsenic affects the methylation of DYM geneCTDPMID:25304211
DymRatbenzo[a]pyrene decreases expressionISODym (Mus musculus)6480464Benzo(a)pyrene results in decreased expression of DYM mRNACTDPMID:19770486 and PMID:21715664
DymRatbenzo[a]pyrene affects methylationISODYM (Homo sapiens)6480464Benzo(a)pyrene affects the methylation of DYM promoterCTDPMID:27901495
DymRatbenzo[a]pyrene increases methylationISODym (Mus musculus)6480464Benzo(a)pyrene results in increased methylation of DYM intronCTDPMID:27901495
DymRatbenzo[a]pyrene decreases expressionISODYM (Homo sapiens)6480464Benzo(a)pyrene results in decreased expression of DYM mRNACTDPMID:20064835 more ...
DymRatbenzo[e]pyrene increases methylationISODYM (Homo sapiens)6480464benzo(e)pyrene results in increased methylation of DYM intronCTDPMID:30157460
DymRatbis(2-chloroethyl) sulfide affects expressionEXP 6480464Mustard Gas affects the expression of DYM mRNACTDPMID:15651846
DymRatbisphenol A increases expressionEXP 6480464bisphenol A results in increased expression of DYM mRNACTDPMID:25181051

1 to 20 of 62 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
DymRatbiological_process  ND 159840712/2006: no relevant rat dataRGD 
DymRatbone development involved_inISSUniProtKB:Q7RTS91600115GO_REF:0000024UniProtGO_REF:0000024
DymRatbone development involved_inISODYM (Homo sapiens)1624291 PMID:21280149RGDPMID:21280149
DymRatGolgi organization involved_inISSUniProtKB:Q7RTS91600115GO_REF:0000024UniProtGO_REF:0000024
DymRatGolgi organization involved_inIBAPANTHER:PTN000307154 and UniProtKB:Q7RTS91600115GO_REF:0000033GO_CentralGO_REF:0000033
DymRatGolgi organization involved_inISODYM (Homo sapiens)1624291 PMID:21280149RGDPMID:21280149

Cellular Component
1 to 13 of 13 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
DymRatcytoplasm located_inISSUniProtKB:Q7RTS91600115GO_REF:0000024UniProtGO_REF:0000024
DymRatcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
DymRatcytoplasm located_inIEAUniProtKB-SubCell:SL-00861600115GO_REF:0000044UniProtGO_REF:0000044
DymRatcytoplasm located_inISODYM (Homo sapiens)1624291 PMID:21280149RGDPMID:21280149
DymRatGolgi apparatus located_inIEAUniProtKB-KW:KW-03331600115GO_REF:0000043UniProtGO_REF:0000043
DymRatGolgi apparatus located_inIEAUniProtKB-SubCell:SL-01321600115GO_REF:0000044UniProtGO_REF:0000044
DymRatGolgi apparatus is_active_inIBAPANTHER:PTN000307154 and UniProtKB:Q7RTS91600115GO_REF:0000033GO_CentralGO_REF:0000033
DymRatGolgi apparatus located_inISSUniProtKB:Q7RTS91600115GO_REF:0000024UniProtGO_REF:0000024
DymRatGolgi apparatus located_inIEAUniProtKB:A0A6Q8PF81 and ensembl:ENSP000005016941600115GO_REF:0000107EnsemblGO_REF:0000107
DymRatGolgi apparatus located_inISODYM (Homo sapiens)1624291 PMID:21280149RGDPMID:21280149
DymRatGolgi apparatus located_inISODYM (Homo sapiens) more ...1624291 RGDGO_REF:0000052
DymRatmembrane located_inIEAUniProtKB-SubCell:SL-01621600115GO_REF:0000044UniProtGO_REF:0000044
DymRatmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
1 to 13 of 13 rows

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
DymRatenzyme binding enablesISODYM (Homo sapiens)1624291UniProtKB:P23284 and PMID:21280149RGDPMID:21280149
DymRatprotein binding enablesISODYM (Homo sapiens)1624291UniProtKB:P23284 more ...RGDPMID:21280149


#
Reference Title
Reference Citation
1. Mental retardation and abnormal skeletal development (Dyggve-Melchior-Clausen dysplasia) due to mutations in a novel, evolutionarily conserved gene. Cohn DH, etal., Am J Hum Genet. 2003 Feb;72(2):419-28. Epub 2002 Dec 16.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
PMID:12477932   PMID:21280149  



Dym
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81870,879,835 - 71,176,006 (+)NCBIGRCr8
mRatBN7.21868,605,131 - 68,900,905 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1868,605,185 - 68,900,903 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1870,718,041 - 71,013,638 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01871,386,410 - 71,683,811 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01869,244,060 - 69,539,675 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01870,996,074 - 71,313,033 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1870,996,044 - 71,313,084 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01870,178,416 - 70,449,688 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41871,889,053 - 72,188,251 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11871,962,174 - 72,261,226 (+)NCBI
Celera1866,780,263 - 67,073,707 (+)NCBICelera
Cytogenetic Map18q12.2NCBI
DYM
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381849,036,387 - 49,460,645 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1849,036,387 - 49,461,347 (-)EnsemblGRCh38hg38GRCh38
GRCh371846,562,757 - 46,987,015 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361844,824,170 - 45,241,077 (-)NCBINCBI36Build 36hg18NCBI36
Build 341844,824,169 - 45,241,077NCBI
Celera1843,423,709 - 43,842,456 (-)NCBICelera
Cytogenetic Map18q21.1NCBI
HuRef1843,422,918 - 43,840,755 (-)NCBIHuRef
CHM1_11846,565,142 - 46,982,392 (-)NCBICHM1_1
T2T-CHM13v2.01849,231,816 - 49,658,383 (-)NCBIT2T-CHM13v2.0
Dym
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391875,151,772 - 75,420,037 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1875,151,852 - 75,420,035 (+)EnsemblGRCm39 Ensembl
GRCm381875,018,699 - 75,286,966 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1875,018,781 - 75,286,964 (+)EnsemblGRCm38mm10GRCm38
MGSCv371875,178,426 - 75,446,620 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361875,144,137 - 75,412,331 (+)NCBIMGSCv36mm8
Celera1876,242,337 - 76,521,558 (+)NCBICelera
Cytogenetic Map18E3NCBI
cM Map1850.97NCBI
Dym
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540234,150,783 - 34,542,507 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540234,150,783 - 34,541,944 (-)NCBIChiLan1.0ChiLan1.0
DYM
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21766,578,224 - 66,989,529 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11852,268,524 - 52,682,132 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01842,427,493 - 42,842,450 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11845,780,831 - 46,179,616 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1845,783,379 - 46,162,835 (-)Ensemblpanpan1.1panPan2
DYM
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1779,286,558 - 79,629,451 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl779,286,614 - 79,629,043 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha778,691,499 - 79,034,045 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0779,353,467 - 79,696,604 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl779,353,400 - 79,697,033 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1779,068,269 - 79,410,974 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0779,098,408 - 79,441,226 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0779,383,285 - 79,726,463 (+)NCBIUU_Cfam_GSD_1.0
Dym
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494438,237,505 - 38,575,582 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649713,476,326 - 13,818,059 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649713,476,376 - 13,816,515 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DYM
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl198,638,339 - 99,024,642 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1198,642,506 - 99,024,664 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21108,216,906 - 108,352,210 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DYM
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11831,513,665 - 31,902,064 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1831,513,735 - 31,901,811 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660505,734,433 - 6,137,618 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dym
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477812,541,566 - 12,977,314 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477812,541,566 - 12,977,319 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Dym
1973 total Variants


Assembly: mRatBN7.2

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain Variant Page
18 68733177 68733178 G A snv SHRSP/A3NCrl (2019NG), SHRSP/A3NCrl (2019) View more Information


Assembly: Rnor_6.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain Variant Page
18 71136068 71136069 G A snv F344/NRrrc (MCW) View more Information
18 71145511 71145512 G A snv SHRSP/A3NCrl (2019) View more Information

Predicted Target Of
Summary Value
Count of predictions:282
Count of miRNA genes:129
Interacting mature miRNAs:137
Transcripts:ENSRNOT00000024950, ENSRNOT00000066336
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 46 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1331733Bp233Blood pressure QTL 2333.97196arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182479697779788953Rat
12904069Cm123Cardiac mass QTL 1230.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)185253976376104388Rat
12904070Cm124Cardiac mass QTL 1240.01heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)185253976376104388Rat
2303584Gluco55Glucose level QTL 552blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)184852004483828827Rat
12904071Am18Aortic mass QTL 180.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)185253976376104388Rat
12904067Cm122Cardiac mass QTL 1220.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)185253976376104388Rat
61384Bp48Blood pressure QTL 4819.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)186062231177209844Rat
1331741Bp232Blood pressure QTL 2323.59112arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)182137289383213037Rat
2301417Bp319Blood pressure QTL 3190.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)185253976376104388Rat
1298072Cia26Collagen induced arthritis QTL 263.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)185470976983828827Rat

1 to 10 of 46 rows
D18Rat83  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81870,906,674 - 70,906,819 (+)Marker Load Pipeline
mRatBN7.21868,631,562 - 68,631,709 (+)MAPPERmRatBN7.2
Rnor_6.01871,028,936 - 71,029,080NCBIRnor6.0
Rnor_5.01870,165,216 - 70,165,360UniSTSRnor5.0
RGSC_v3.41871,916,282 - 71,916,427RGDRGSC3.4
RGSC_v3.41871,916,283 - 71,916,427UniSTSRGSC3.4
RGSC_v3.11871,989,396 - 71,989,686RGD
Celera1866,806,536 - 66,806,680UniSTS
SHRSP x BN Map1843.2499UniSTS
SHRSP x BN Map1843.2499RGD
Cytogenetic Map18q12.3UniSTS
RH134522  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21868,900,668 - 68,900,857 (+)MAPPERmRatBN7.2
Rnor_6.01871,312,797 - 71,312,985NCBIRnor6.0
Rnor_5.01870,449,452 - 70,449,640UniSTSRnor5.0
RGSC_v3.41872,188,015 - 72,188,203UniSTSRGSC3.4
Celera1867,073,471 - 67,073,659UniSTS
RH 3.4 Map18710.5UniSTS
Cytogenetic Map18q12.3UniSTS
RH143452  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21868,725,014 - 68,725,137 (+)MAPPERmRatBN7.2
Rnor_6.01871,137,349 - 71,137,471NCBIRnor6.0
Rnor_5.01870,273,614 - 70,273,736UniSTSRnor5.0
RGSC_v3.41872,011,886 - 72,012,008UniSTSRGSC3.4
Celera1866,897,029 - 66,897,151UniSTS
RH 3.4 Map18710.4UniSTS
Cytogenetic Map18q12.3UniSTS
G47243  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21868,817,139 - 68,817,391 (+)MAPPERmRatBN7.2
Rnor_6.01871,229,437 - 71,229,686NCBIRnor6.0
Rnor_5.01870,365,890 - 70,366,139UniSTSRnor5.0
RGSC_v3.41872,104,065 - 72,104,314UniSTSRGSC3.4
Celera1866,989,187 - 66,989,436UniSTS
Cytogenetic Map18q12.3UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31


1 to 22 of 22 rows
RefSeq Transcripts NM_001106133 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008772103 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600877 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600878 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600879 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600880 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600881 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039096637 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039096638 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277161 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277162 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277164 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277165 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC098944 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC168151 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB712341 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CO558582 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DV722630 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EV765460 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 22 of 22 rows

Ensembl Acc Id: ENSRNOT00000024950   ⟹   ENSRNOP00000024950
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1868,605,226 - 68,900,898 (+)Ensembl
Rnor_6.0 Ensembl1870,996,044 - 71,313,084 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000066336   ⟹   ENSRNOP00000060744
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1868,605,202 - 68,900,903 (+)Ensembl
Rnor_6.0 Ensembl1870,996,140 - 71,313,031 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000110740   ⟹   ENSRNOP00000081467
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1868,605,185 - 68,900,863 (+)Ensembl
RefSeq Acc Id: NM_001106133   ⟹   NP_001099603
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81870,880,332 - 71,176,006 (+)NCBI
mRatBN7.21868,605,202 - 68,900,905 (+)NCBI
Rnor_6.01870,996,140 - 71,313,033 (+)NCBI
Rnor_5.01870,178,416 - 70,449,688 (+)NCBI
RGSC_v3.41871,889,053 - 72,188,251 (+)RGD
Celera1866,780,263 - 67,073,707 (+)RGD
Sequence:
RefSeq Acc Id: XM_008772103   ⟹   XP_008770325
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81870,879,835 - 71,176,006 (+)NCBI
mRatBN7.21868,605,138 - 68,900,905 (+)NCBI
Rnor_6.01870,996,076 - 71,313,033 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017600877   ⟹   XP_017456366
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81870,879,835 - 71,176,006 (+)NCBI
mRatBN7.21868,605,134 - 68,900,905 (+)NCBI
Rnor_6.01870,996,074 - 71,313,033 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017600878   ⟹   XP_017456367
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81870,880,624 - 71,176,006 (+)NCBI
mRatBN7.21868,605,481 - 68,900,905 (+)NCBI
Rnor_6.01870,996,382 - 71,313,033 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017600879   ⟹   XP_017456368
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81870,879,835 - 71,176,006 (+)NCBI
mRatBN7.21868,605,135 - 68,900,905 (+)NCBI
Rnor_6.01870,996,075 - 71,313,033 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017600880   ⟹   XP_017456369
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81870,879,835 - 71,176,006 (+)NCBI
mRatBN7.21868,605,136 - 68,900,905 (+)NCBI
Rnor_6.01870,996,075 - 71,313,033 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039096637   ⟹   XP_038952565
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81870,879,835 - 71,176,006 (+)NCBI
mRatBN7.21868,605,131 - 68,900,905 (+)NCBI
RefSeq Acc Id: XM_039096638   ⟹   XP_038952566
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81870,879,835 - 71,176,006 (+)NCBI
mRatBN7.21868,605,135 - 68,900,905 (+)NCBI
RefSeq Acc Id: XM_063277161   ⟹   XP_063133231
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81870,879,835 - 71,176,006 (+)NCBI
RefSeq Acc Id: XM_063277162   ⟹   XP_063133232
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81870,879,835 - 71,176,006 (+)NCBI
RefSeq Acc Id: XM_063277164   ⟹   XP_063133234
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81870,879,835 - 71,176,006 (+)NCBI
RefSeq Acc Id: XM_063277165   ⟹   XP_063133235
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81870,879,835 - 71,176,006 (+)NCBI
RefSeq Acc Id: XM_063277166   ⟹   XP_063133236
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81870,879,835 - 71,176,006 (+)NCBI
1 to 5 of 16 rows
1 to 5 of 16 rows
RefSeq Acc Id: NP_001099603   ⟸   NM_001106133
- UniProtKB: D3ZP27 (UniProtKB/TrEMBL),   A6KRI1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008770325   ⟸   XM_008772103
- Peptide Label: isoform X5
- UniProtKB: A0A0H2UHP8 (UniProtKB/TrEMBL),   A6KRI0 (UniProtKB/TrEMBL),   A6KRI1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017456366   ⟸   XM_017600877
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017456369   ⟸   XM_017600880
- Peptide Label: isoform X3
- UniProtKB: B4F766 (UniProtKB/Swiss-Prot),   A6KRI1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017456368   ⟸   XM_017600879
- Peptide Label: isoform X2
- Sequence:

Name Modeler Protein Id AA Range Protein Structure
AF-B4F766-F1-model_v2 AlphaFold B4F766 1-674 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13700871
Promoter ID:EPDNEW_R11393
Type:initiation region
Name:Dym_1
Description:dymeclin
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01870,996,132 - 70,996,192EPDNEW


1 to 21 of 21 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-6987 BioCyc
Ensembl Genes ENSRNOG00000018425 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000024950 ENTREZGENE
  ENSRNOT00000024950.8 UniProtKB/Swiss-Prot
  ENSRNOT00000066336 ENTREZGENE
  ENSRNOT00000110740 ENTREZGENE
  ENSRNOT00000152426 ENTREZGENE
InterPro Dymeclin UniProtKB/Swiss-Prot
NCBI Gene 291433 ENTREZGENE
PANTHER DYMECLIN UniProtKB/Swiss-Prot
  PTHR12895 UniProtKB/Swiss-Prot
Pfam Dymeclin UniProtKB/Swiss-Prot
PhenoGen Dym PhenoGen
RatGTEx ENSRNOG00000018425 RatGTEx
UniProt A0A0H2UHP8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6G5Z6 ENTREZGENE, UniProtKB/TrEMBL
  A6KRI0 ENTREZGENE, UniProtKB/TrEMBL
  A6KRI1 ENTREZGENE, UniProtKB/TrEMBL
  B4F766 ENTREZGENE
  D3ZP27 ENTREZGENE, UniProtKB/TrEMBL
  DYM_RAT UniProtKB/Swiss-Prot
1 to 21 of 21 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Dym  dymeclin   Dym_predicted  dymeclin (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Dym_predicted  dymeclin (predicted)  RGD1309111_predicted  similar to RIKEN cDNA 4933427L07 (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-20 RGD1309111_predicted  similar to RIKEN cDNA 4933427L07 (predicted)  LOC291433_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC291433_predicted  similar to RIKEN cDNA 4933427L07 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL