Lztr1 (leucine zipper like post translational regulator 1) - Rat Genome Database

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Gene: Lztr1 (leucine zipper like post translational regulator 1) Rattus norvegicus
Analyze
Symbol: Lztr1
Name: leucine zipper like post translational regulator 1
RGD ID: 1309100
Description: Predicted to enable small GTPase binding activity. Predicted to be involved in negative regulation of Ras protein signal transduction and protein ubiquitination. Predicted to be located in recycling endosome membrane. Predicted to be part of Cul3-RING ubiquitin ligase complex. Predicted to be active in Golgi apparatus. Human ortholog(s) of this gene implicated in several diseases, including Noonan syndrome (multiple); glioblastoma; hepatocellular carcinoma; neurilemmoma; and schwannomatosis (multiple). Orthologous to human LZTR1 (leucine zipper like post translational regulator 1); INTERACTS WITH 6-propyl-2-thiouracil; endosulfan; methimazole.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: leucine-zipper-like transcription regulator 1; leucine-zipper-like transcriptional regulator 1; leucine-zipper-like transcriptional regulator, 1; LOC360745
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81196,991,956 - 97,008,127 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1196,991,590 - 97,007,851 (-)EnsemblGRCr8
mRatBN7.21183,487,717 - 83,503,896 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1183,487,717 - 83,503,633 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1192,215,468 - 92,231,027 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01184,876,627 - 84,892,186 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01183,930,235 - 83,945,794 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01187,381,638 - 87,397,849 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1187,381,899 - 87,397,498 (+)Ensemblrn6Rnor6.0
Rnor_5.01190,432,972 - 90,449,143 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41185,479,494 - 85,495,053 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1182,256,659 - 82,272,218 (-)NCBICelera
RGSC_v3.11185,520,301 - 85,542,781 (-)NCBI
Cytogenetic Map11q23NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. A novel pretherapeutic gene expression-based risk score for treatment guidance in gastric cancer. Bauer L, etal., Ann Oncol. 2018 Jan 1;29(1):127-132. doi: 10.1093/annonc/mdx685.
2. A mosaic pattern of INI1/SMARCB1 protein expression distinguishes Schwannomatosis and NF2-associated peripheral schwannomas from solitary peripheral schwannomas and NF2-associated vestibular schwannomas. Caltabiano R, etal., Childs Nerv Syst. 2017 Jun;33(6):933-940. doi: 10.1007/s00381-017-3340-2. Epub 2017 Apr 1.
3. Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma. Cancer Genome Atlas Research Network. Electronic address: wheeler@bcm.edu and Cancer Genome Atlas Research Network, Cell. 2017 Jun 15;169(7):1327-1341.e23. doi: 10.1016/j.cell.2017.05.046.
4. RIT1 oncoproteins escape LZTR1-mediated proteolysis. Castel P, etal., Science. 2019 Mar 15;363(6432):1226-1230. doi: 10.1126/science.aav1444.
5. Providing more evidence on LZTR1 variants in Noonan syndrome patients. Chinton J, etal., Am J Med Genet A. 2020 Feb;182(2):409-414. doi: 10.1002/ajmg.a.61445. Epub 2019 Dec 11.
6. The integrated landscape of driver genomic alterations in glioblastoma. Frattini V, etal., Nat Genet. 2013 Oct;45(10):1141-9. doi: 10.1038/ng.2734. Epub 2013 Aug 5.
7. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
8. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
9. LZTR1-Related Hypertrophic Cardiomyopathy Without Typical Noonan Syndrome Features. Jenkins J, etal., Circ Genom Precis Med. 2020 Apr;13(2):e002690. doi: 10.1161/CIRCGEN.119.002690. Epub 2020 Jan 31.
10. Targeted next-generation sequencing for differential diagnosis of neurofibromatosis type 2, schwannomatosis, and meningiomatosis. Louvrier C, etal., Neuro Oncol. 2018 Jun 18;20(7):917-929. doi: 10.1093/neuonc/noy009.
11. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
12. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
13. Germline loss-of-function mutations in LZTR1 predispose to an inherited disorder of multiple schwannomas. Piotrowski A, etal., Nat Genet. 2014 Feb;46(2):182-7. doi: 10.1038/ng.2855. Epub 2013 Dec 22.
14. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
15. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
16. The Noonan Syndrome Gene Lztr1 Controls Cardiovascular Function by Regulating Vesicular Trafficking. Sewduth RN, etal., Circ Res. 2020 May 8;126(10):1379-1393. doi: 10.1161/CIRCRESAHA.119.315730. Epub 2020 Mar 16.
17. Mutations in LZTR1 add to the complex heterogeneity of schwannomatosis. Smith MJ, etal., Neurology. 2015 Jan 13;84(2):141-7. doi: 10.1212/WNL.0000000000001129. Epub 2014 Dec 5.
Additional References at PubMed
PMID:12477932   PMID:16356934   PMID:30442762   PMID:30442766   PMID:31904090  


Genomics

Comparative Map Data
Lztr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81196,991,956 - 97,008,127 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1196,991,590 - 97,007,851 (-)EnsemblGRCr8
mRatBN7.21183,487,717 - 83,503,896 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1183,487,717 - 83,503,633 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1192,215,468 - 92,231,027 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01184,876,627 - 84,892,186 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01183,930,235 - 83,945,794 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01187,381,638 - 87,397,849 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1187,381,899 - 87,397,498 (+)Ensemblrn6Rnor6.0
Rnor_5.01190,432,972 - 90,449,143 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41185,479,494 - 85,495,053 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1182,256,659 - 82,272,218 (-)NCBICelera
RGSC_v3.11185,520,301 - 85,542,781 (-)NCBI
Cytogenetic Map11q23NCBI
LZTR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382220,982,297 - 20,999,032 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2220,982,223 - 20,999,035 (+)Ensemblhg38GRCh38
GRCh372221,336,586 - 21,353,321 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362219,666,558 - 19,683,326 (+)NCBIBuild 36Build 36hg18NCBI36
Build 342219,661,209 - 19,677,879NCBI
Celera224,827,905 - 4,844,645 (+)NCBICelera
Cytogenetic Map22q11.21NCBI
HuRef224,604,854 - 4,621,598 (+)NCBIHuRef
CHM1_12221,336,755 - 21,353,527 (+)NCBICHM1_1
T2T-CHM13v2.02221,391,107 - 21,407,823 (+)NCBIT2T-CHM13v2.0
Lztr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391617,326,124 - 17,344,197 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1617,326,552 - 17,344,197 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381617,508,260 - 17,526,333 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1617,508,688 - 17,526,333 (+)Ensemblmm10GRCm38
MGSCv371617,509,064 - 17,526,423 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361617,422,534 - 17,439,893 (+)NCBIMGSCv36mm8
Celera1618,082,040 - 18,099,435 (+)NCBICelera
Cytogenetic Map16A3NCBI
cM Map1610.85NCBI
Lztr1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544219,315,427 - 19,333,522 (-)Ensembl
ChiLan1.0NW_00495544219,315,427 - 19,333,361 (-)NCBIChiLan1.0ChiLan1.0
LZTR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22330,688,368 - 30,705,824 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12233,237,296 - 33,254,762 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0223,206,019 - 3,223,050 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12219,695,348 - 19,713,007 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2219,695,228 - 19,713,007 (+)EnsemblpanPan2panpan1.1
LZTR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12630,501,793 - 30,519,698 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2630,503,071 - 30,519,611 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2630,460,228 - 30,477,473 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02631,910,805 - 31,928,017 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2631,910,811 - 31,943,250 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12629,956,683 - 29,973,831 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02629,580,661 - 29,597,796 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02630,669,630 - 30,686,843 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Lztr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118140,230,562 - 140,248,621 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366192,505,542 - 2,523,500 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366192,505,300 - 2,523,500 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LZTR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1450,576,624 - 50,590,397 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11450,576,413 - 50,590,397 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21454,025,428 - 54,038,534 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103222956
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1194,917,381 - 4,935,174 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl194,904,050 - 4,918,224 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
ChlSab1.1 Ensembl194,918,360 - 4,933,439 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660852,034,445 - 2,052,891 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lztr1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624945691,059 - 709,564 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624945691,063 - 709,599 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Lztr1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v142,761,289 - 2,777,631 (+)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:114
Count of miRNA genes:91
Interacting mature miRNAs:97
Transcripts:ENSRNOT00000002554
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)117385089499753367Rat
4889859Pur28Proteinuria QTL 2819.50.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)115892833699753367Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)116796218499753367Rat
631506Bp104Blood pressure QTL 1042.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)117330831599753367Rat
7411658Foco27Food consumption QTL 2716.20.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)116985594399753367Rat
1549848Bvd6Brain ventricular dilatation QTL 63.10.0001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)117961851999753367Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 92 59 6 356 192 11 142 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000002554   ⟹   ENSRNOP00000002554
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1196,991,590 - 97,007,851 (-)Ensembl
mRatBN7.2 Ensembl1183,487,717 - 83,503,633 (-)Ensembl
Rnor_6.0 Ensembl1187,381,899 - 87,397,498 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000101549   ⟹   ENSRNOP00000082766
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1196,992,293 - 97,007,851 (-)Ensembl
mRatBN7.2 Ensembl1183,487,717 - 83,503,633 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000109441   ⟹   ENSRNOP00000076809
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1196,992,293 - 97,007,851 (-)Ensembl
mRatBN7.2 Ensembl1183,487,717 - 83,503,633 (-)Ensembl
RefSeq Acc Id: NM_001108326   ⟹   NP_001101796
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81196,992,292 - 97,007,851 (-)NCBI
mRatBN7.21183,488,053 - 83,503,612 (-)NCBI
Rnor_6.01187,381,954 - 87,397,513 (+)NCBI
Rnor_5.01190,432,972 - 90,449,143 (+)NCBI
RGSC_v3.41185,479,494 - 85,495,053 (-)RGD
Celera1182,256,659 - 82,272,218 (-)RGD
Sequence:
RefSeq Acc Id: XM_006248707   ⟹   XP_006248769
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81196,991,956 - 97,008,127 (-)NCBI
mRatBN7.21183,487,717 - 83,503,896 (-)NCBI
Rnor_6.01187,381,638 - 87,397,849 (+)NCBI
Rnor_5.01190,432,972 - 90,449,143 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039088534   ⟹   XP_038944462
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81196,991,956 - 97,007,212 (-)NCBI
mRatBN7.21183,487,717 - 83,502,978 (-)NCBI
RefSeq Acc Id: XM_063270661   ⟹   XP_063126731
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81196,991,956 - 97,003,841 (-)NCBI
RefSeq Acc Id: NP_001101796   ⟸   NM_001108326
- UniProtKB: B5DFI4 (UniProtKB/TrEMBL),   A6JSL5 (UniProtKB/TrEMBL),   A0A8I5Y0T3 (UniProtKB/TrEMBL),   F7FP96 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006248769   ⟸   XM_006248707
- Peptide Label: isoform X1
- UniProtKB: A0A8I5Y0T3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000002554   ⟸   ENSRNOT00000002554
RefSeq Acc Id: XP_038944462   ⟸   XM_039088534
- Peptide Label: isoform X2
- UniProtKB: A0A8I5Y0T3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000076809   ⟸   ENSRNOT00000109441
Ensembl Acc Id: ENSRNOP00000082766   ⟸   ENSRNOT00000101549
RefSeq Acc Id: XP_063126731   ⟸   XM_063270661
- Peptide Label: isoform X2
- UniProtKB: A0A8I5Y0T3 (UniProtKB/TrEMBL)
Protein Domains
BTB

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B5DFI4-F1-model_v2 AlphaFold B5DFI4 1-837 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698319
Promoter ID:EPDNEW_R8843
Type:initiation region
Name:Lztr1_1
Description:leucine-zipper-like transcription regulator 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01187,381,929 - 87,381,989EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309100 AgrOrtholog
BioCyc Gene G2FUF-20591 BioCyc
Ensembl Genes ENSRNOG00000001870 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000002554 ENTREZGENE
  ENSRNOT00000002554.8 UniProtKB/TrEMBL
  ENSRNOT00000101549 ENTREZGENE
  ENSRNOT00000101549.2 UniProtKB/TrEMBL
  ENSRNOT00000109441.2 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.420 UniProtKB/TrEMBL
  2.120.10.80 UniProtKB/TrEMBL
  Potassium Channel Kv1.1, Chain A UniProtKB/TrEMBL
InterPro BTB/POZ-like UniProtKB/TrEMBL
  BTB/POZ_fold UniProtKB/TrEMBL
  Gal_Oxase/kelch_b-propeller UniProtKB/TrEMBL
  Kelch-typ_b-propeller UniProtKB/TrEMBL
  Kelch_1 UniProtKB/TrEMBL
  LZTR1/Attractin UniProtKB/TrEMBL
KEGG Report rno:360745 UniProtKB/TrEMBL
NCBI Gene 360745 ENTREZGENE
PANTHER LEUCINE-ZIPPER-LIKE TRANSCRIPTIONAL REGULATOR 1 UniProtKB/TrEMBL
  LEUCINE-ZIPPER-LIKE TRANSCRIPTIONAL REGULATOR 1 UniProtKB/TrEMBL
Pfam BTB UniProtKB/TrEMBL
  Kelch_1 UniProtKB/TrEMBL
  Kelch_KLHDC2_KLHL20_DRC7 UniProtKB/TrEMBL
PhenoGen Lztr1 PhenoGen
PROSITE BTB UniProtKB/TrEMBL
RatGTEx ENSRNOG00000001870 RatGTEx
SMART BTB UniProtKB/TrEMBL
  Kelch UniProtKB/TrEMBL
Superfamily-SCOP BTB/POZ_fold UniProtKB/TrEMBL
  SSF117281 UniProtKB/TrEMBL
  SSF50965 UniProtKB/TrEMBL
UniProt A0A8I5Y0T3 ENTREZGENE, UniProtKB/TrEMBL
  A0ABZ3NNP9_RAT UniProtKB/TrEMBL
  A6JSL5 ENTREZGENE, UniProtKB/TrEMBL
  B5DFI4 ENTREZGENE
  F7FP96 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A8I5ZVJ5 UniProtKB/TrEMBL
  B5DFI4 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-04-18 Lztr1  leucine zipper like post translational regulator 1  Lztr1  leucine-zipper-like transcription regulator 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-23 Lztr1  leucine-zipper-like transcription regulator 1  Lztr1  leucine-zipper-like transcriptional regulator, 1   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Lztr1  leucine-zipper-like transcriptional regulator, 1   Lztr1_predicted  leucine-zipper-like transcriptional regulator, 1 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Lztr1_predicted  leucine-zipper-like transcriptional regulator, 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED